Efficacy of Trimebutine Maleate (Trimedat®) in the Treatment of Patients with Functional Dyspepsia: Results of the “TREND” Observational Study by S. S. Kardasheva, I. M. Kartavenko, N. B. Maksimova, E. Yu. Yurieva, I. R. Popova, Ch. S. Pavlov, V. T. Ivashkin

“…The treatment was performed using trimebutine (Trimedat®) in a standard dosage of 200 mg × 3 times a day for 28 days.Results. In the group under study, 45 (45 %), 3 (3 %) and 52 (52 %) patients suffered from epigastric pain syndrome (EPS), postprandial distress syndrome (PPDS) and a combination of both syndromes, respectively. …”
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Reaching the Peripheral Regional Growth Centre by Jörgen Gren

“…Indeed, it seems as if infrastructure investments under the Structural Funds have actually been quite successful in reducing the gap between core and periphery. …”
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Bruton’s tyrosine kinase inhibition re-sensitizes multidrug-resistant DLBCL tumors driven by BCL10 gain-of-function mutants to venetoclax by Caroline A. Coughlin, Dhanvantri Chahar, Marianna Lekakis, Abdessamad A. Youssfi, Lingxiao Li, Evan Roberts, Natalia Campos Gallego, Claude-Henry Volmar, Ola Landgren, Shaun Brothers, Anthony J. Griswold, Catalina Amador, Daniel Bilbao, Francesco Maura, Jonathan H. Schatz

“…Up-regulation of anti-apoptotic genes increases mitochondrial membrane potential, underlying multidrug resistance. Increased expression of BCL2, BCL2L1 (BCL-XL), and BCL2A1 (BFL1) drives resistance to venetoclax, but expression can be overcome by the potent non-covalent BTK inhibitor pirtobrutinib. …”
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A multitasking ant system for multi-depot pick-up and delivery location routing problem with time window by Haoyuan Lv, Ruochen Liu, Jianxia Li

“…They are powerless to simultaneously explore the solution spaces of multiple routing tasks under different location schemes. Furthermore, ignoring the potential general knowledge among different schemes leads to redundant optimization. …”
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Kinetic, Equilibrium and thermodynamic studies on the biosorption of Cd(II) from aqueous solutions by the leaf biomass of <i>Calotropis procera</i> – ‘Sodom apple’ by Babalola J Oyebamiji, LC Overah, Adesola Babarinde, Vincent O Oninla, A Olatunde

“…The calculated thermodynamic parameters (ΔG° -4.846 kJmol-1, ΔH° 10.60 kJmol-1 and ΔS° 0.052 kJK-1mol1) showed that the biosorption of Cd (II) is feasible, spontaneous, endothermic and highly disordered in nature under the experimental conditions. These findings indicate that the leaf of Calotropis procera could be employed in the removal of Cd (II) from industrial effluents. …”
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Altered resting-state cerebral blood flow and its relationship with molecular architecture in tremor dominant Parkinson’s disease by Shangpei Wang, Yajie Cai, Yibin Zhao, Yongqiang Yu, Xianwen Chen, Longsheng Wang

“…Background: The resting-state cerebral blood flow (CBF) alterations in Parkinson’s disease (PD) patients and tremor-dominant (TD) subtype have been explored. However, the underlying molecular architecture correlated with the altered CBF remains unknown. …”
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Risk Factors and Prevention of Upper Gastrointestinal Complications Associated with Nonsteroidal Anti-Inflammatory Drugs by N. V. Bakulina, S. V. Tikhonov, K. A. Nagornova

“…Esomeprazole has a number of pharmacokinetic advantages — a large area under the pharmacokinetic curve, the ability to inhibit CYP4502C19, which determines the high efficiency of therapy in fast and ultrafast metabolizers. …”
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TEACHING AND ASSESSING INDEPENDENT LISTENING IN AN ONLINE COURSE FOR TRANSLATION MAJORS by Olga G. Kvasova, Nataliia K. Liamzina, Roksoliana I. Radchuk, Yulia I. Trykashna

“…Logs/journals/portfolios belong to alternative assessments, which are still innovative and under-researched in language pedagogy, although reflecting the much-welcomed shift from assessment of learning towards assessment for learning.  …”
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Machine Learning Applications to Dust Storms: A Meta-Analysis by Reem K. Alshammari, Omer Alrwais, Mehmet Sabih Aksoy

“…It aims to compare the applied models and the types of data used in the literature under study. Given that the location of a dust storm event is essential, the properties of dust storms are discussed in relation to the region. …”
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Quantifying the sources and health risks of groundwater nitrate via dual NO isotopes and Monte Carlo simulations in a developed planting-breeding area by Jianwei Liu, Shuo Qiao, Shilong Zhao, Hui Chen, Yong Wu, Donghao Li, Ping Liu, Ling Li

“…However, the contribution of N fertilizer may be underestimated because it has undergone a long-term applied history and have progressively accumulated in the soil, and then promoted the entry of groundwater under frequent rainfall and irrigation practices. …”
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Iron(III) edta-accelerated growth of gold/silver core/shell nanoparticles for wide-range colorimetric detection of hydrogen peroxide by Mahdi Hemmati, Amir Hossein Q. Selakjan, Forough Ghasemi

“…This characteristic was exploited to measure different concentrations of H2O2. Under well-optimized conditions, various concentrations of H2O2 ranging from 1.0 to 50 µΜ have shown an acceptable linear relationship with different colors and, with a limit of detection (LOD) of 230 nM. …”
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Implementation of patient-centred care: which organisational determinants matter from decision maker’s perspective? Results from a qualitative interview study across various health... by Lena Ansmann, Holger Pfaff, Kira Isabel Hower, Vera Vennedey, Hendrik Ansgar Hillen, Ludwig Kuntz, Stephanie Stock

“…Objectives Health and social care systems, organisations and providers are under pressure to organise care around patients’ needs with constrained resources. …”
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Infertility and Social Issue Have the Most Significant Impact on Health-Related Quality of Life Among Polycystic Ovarian Syndrome Women in South India by L. Hariprasath, D. Selvakumar, V. Dharani, K. K. Durgalakshmi, V. G. Abilash, T. S. Gopenath, S. Nishu

“…Settings and Design: A total of 126 females in the first phase and 356 females in the second phase between the age group of 18–40 years characterised under the Rotterdam criteria were selected for the study. …”
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Effect of laser and light emitting diode bleaching techniques on micro-leakage of dental composite postoperatively using two different bonding systems by Shalaw S. Jawhar, Bassam K. Amin

“…When the scores of micro-leakage of the six subgroups were compared, the differences among the groups were found to be statistically significant (p < 0.001). there was no significant difference found between the adhesive systems after treatment with the same bleaching techniques. Conclusion: Under the conditions of this study, micro-leakage of composite resin restorations differs according to the bleaching techniques used with no significant difference was found between the adhesive systems, and restorations post bleaching procedure was necessitate replacing by the clinician due adverse effects on tooth restoration interface. …”
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CHURCH RESPONSE TO SECURITY CHALLENGES IN THE 21ST CENTURY: THE NIGERIAN EXPERIENCE by Oyebode Paul Jegede, Abare Yunuwa Kallah

“…The study discovered that no nation can develop where lives and properties are constantly under threat. The paper also recommended that church leaders should use their pulpits to promote awareness among members of the Church on the need for security of their lives and loved ones and the society at large. …”
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Evaluation of conditioning temperature and retention time on Enterococcus faecium inactivation, vitamin stability, metabolizable energy, and amino acid digestibility by J.I. Vargas, W.J. Pacheco, L.M. Almeida, C.W. Starkey, E. Monu

“…In contrast, water-soluble vitamins were stable under varying conditioning temperatures and retention times. …”
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A Global Bibliometric Analysis of Loneliness During the COVID-19 Pandemic: Future research and policy implications by Trinh Thi Xuan Nguyen, Sumeet Lal, Yoshihiko Kadoya

“… Introduction: Under the profound impacts of the COVID-19 pandemic, loneliness has become a major public health concern worldwide. …”
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Uncovering the genetic basis of milk production traits in Mexican Holstein cattle based on individual markers and genomic windows. by José G Cortes-Hernández, Adriana García-Ruiz, Francisco Peñagaricano, Hugo H Montaldo, Felipe J Ruiz-López

“…The most significant regions were associated with two or more phenotypic traits, such as one region on chromosome 14 that harbors the DGAT1, EXOSC4, PPP1R16A, and FOXH1 genes, which affect all the traits under study. In general, the utilization of genomic windows resulted in a greater proportion of genetic variance explained by milk production traits.…”
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Donor age contributes more to the rheological properties of stored red blood cells than donor sex and biological age distribution by Olga Mykhailova, Mackenzie Brandon-Coatham, Sanaz Hemmatibardehshahi, Mahsa Yazdanbakhsh, Carly Olafson, Qi-Long Yi, Tamir Kanias, Jason P. Acker

“…Teen O-RBCs, particularly from males, had higher elongation indices, both under isotonic conditions and in the presence of an increasing osmotic gradient. …”
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Networking Salt Inducible Kinase 1 Regulatory Perturbations on Type 2 Diabetes- Breast Cancer Co-Morbidity Associated Molecular Bridge by Durrani I.A., John P., Bhatti A.

“…Type 2 diabetes mellitus (T2DM) is associated with a 16% elevated risk of breast cancer (BC). However, the underlying molecular mechanisms are yet to be fully understood. …”
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