Identification of HOXA9 methylation as an epigenetic biomarker predicting prognosis and guiding treatment choice in acute myeloid leukemia by Fei Xie, Ting-juan Zhang, Xin-long Zhang, Zi-jun Xu, Liang Qiao, Yun Wang, Yang-jing Zhao, Jun Qian, Jing-dong Zhou

“…However, very few studies determined the DNA methylation-mediated epigenetic regulation of the HOXA cluster genes in AML. …”
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An optimized data analytics pipeline for improving healthcare diagnosis using ensemble learning by Lomat Haider Chowdhury, Shaira Tabassum, Swakkhar Shatabda, Ashir Ahmed

“…However, the cost of healthcare diagnosis makes people indifferent to going through the process. …”
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Nutritional and General Awareness of Vitamin D Status among Adult Population in Sulaymaniyah Governorate, Kurdistan Region, Iraq: A Cross-Sectional Study by Reder Rafiq Mohammed Salih, Fadhluddin Nasruddin Shakor, Dalia Ardal Ali, Rafiq Mohammed Salih Rashid

“…In Iraq, vitamin D deficiency and inadequacy are highly prevalent. However, public knowledge on this problem is scarce. …”
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Association analysis of suicide risk assessed with Mini International Neuropsychiatric Interviews’ Suicidality Module in adolescents with non suicidal self injury disorder by Shuo Geng, Shuo Geng, Wen Zhang, Xiang Gao, Lele Qu, Xueping Zheng, Jian Sun, Mingdong Xu, Hua Lin, Xueyu Jia, Xu Zhang

“…ObjectiveMany adolescents with non suicidal self injury disorder have suicidal ideation. However, the specific characteristics of adolescents with NSSI-D that contribute to high suicide risk remain unclear. …”
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Inhaled corticosteroids' effect on COVID-19 patients: A systematic review and meta-analysis of randomized controlled trials by Yasra Badi, Mohamed Hammad, Abdelrahman G. Tawfik, Mona Muhe Eldeen Eshag, Mahmoud M. Elhady, Khaled Mohamed Ragab, Anas Zakarya Nourelden, Mohamed Hesham Gamal, Ahmed Hashem Fathallah

“…Our study showed a significant decrease in the LOS in ICS patients over placebo (MD = -1.52, 95% CI \[-2.77 to -0.28\], *p-value* = 0.02). …”
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Evaluating pre-processing and deep learning methods in medical imaging: Combined effectiveness across multiple modalities by Thien B. Nguyen-Tat, Tran Quang Hung, Pham Tien Nam, Vuong M. Ngo

“…Advanced computational techniques, particularly preprocessing methods and deep learning models, have demonstrated significant potential for improving medical image analysis. However, determining the optimal combination of these techniques across different types of medical images remains a challenge. …”
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Safety and accuracy of digitally supported primary and secondary urgent care telephone triage in England: an observational study using routine data by Vanashree Sexton, Catherine Grimley, Jeremy Dale, Helen Atherton, Gary Abel

“…., service provider 2, OR = 5.61; CI:3.36–9.36) and individual clinician (OR covering the 95% midrange = 16.15) conducting triage were the characteristics most greatly associated with this potential under-triage; p < 0.001 for all. …”
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Comprehensive genomic and transcriptomic profiling of pulmonary nodules in synchronous multiple primary lung cancer by Xingsheng Liu, Kun Qian, Lei Su, Xiaoru Tian, Xin Zhao, Tengteng Wang, Li Han, Zhenzhen Li, Peilong Zhang, Ruotian Wang, Baodong Liu, Yuanbo Li, Xiaogang Tan, Yi Zhang

“…Abstract Background Synchronous multiple primary lung cancer (sMPLC) exhibits distinct histopathological characteristics among pulmonary nodules. However, a comprehensive understanding of the somatic mutation landscape and transcriptome heterogeneity is lacking. …”
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An analysis of controlled human infection studies registered on ClinicalTrials.gov by James Wilkinson, Joshua Osowicki, Euzebiusz Jamrozik, Ian J Saldanha, Meta Roestenberg, Danny Toomey, Jupiter Adams-Phipps, John Pietro, Jake Littman, Steffen Kamenicek, Daniel Kaufman

“…In general, medium-sized, publicly funded trials tended to have more discrepancies in reporting, which may reflect the resources typically available to large, privately funded trials or the relative ease of reporting in smaller trials with fewer overall AEs. These results highlight the need to facilitate clear and consistent reporting in CHIS.PROSPERO registration number CRD42022330047.…”
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A comprehensive analysis of molecular characteristics of hot and cold tumor of gastric cancer by Chenxi Lv, Tianwei Chen, Jiangtao Li, Yuqiang Shan, Hong Zhou

“…Immune “hot” tumor-related genes were identified, and their functional roles were validated through biological behavior analysis. …”
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A generative whole-brain segmentation model for positron emission tomography images by Wenbo Li, Zhenxing Huang, Hongyan Tang, Yaping Wu, Yunlong Gao, Jing Qin, Jianmin Yuan, Yang Yang, Yan Zhang, Na Zhang, Hairong Zheng, Dong Liang, Meiyun Wang, Zhanli Hu

“…Abstract Purpose Whole-brain segmentation via positron emission tomography (PET) imaging is crucial for advancing neuroscience research and clinical medicine, providing essential insights into biological metabolism and activity within different brain regions. However, the low resolution of PET images may have limited the segmentation accuracy of multiple brain structures. …”
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The prevalence and distribution of malaria in Mpumalanga Province before and during COVID-19 (2017 - 2022) by I Kleinhans, S Mahanjana, F Els, M Mabona, L A Pitso, G Malatje, G Kok, J Raman

“…South Africa (SA) has committed to eliminating malaria by 2028. However, the initial target was set for 2023. Additionally, the ongoing COVID-19 pandemic and the emergence of drug and insecticide resistance have been identified as potential stumbling blocks in the achievement of this goal. …”
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VICTIM OF AN OFFENCE: LEGAL AND ECONOMIC ANALYSIS IN AN INTERJURISDICTIONAL CONTEXT by Andrii Borovyk, Oleksandr Golovach, Oleksandr Shyra

“…Moreover, the study underscores the pivotal role of international legal instruments, such as the EU's Directive 2012/29/EU and the International Criminal Court's provisions, in promoting universal enhancement of victims' rights. …”
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Quantity and quality of napping to mitigate fatigue and sleepiness among nurses working long night shifts: a prospective observational study by Kazuhiro Watanabe, Inaho Shishido, Yoichi M. Ito, Rika Yano

“…Abstract Background Napping during night shifts is a countermeasure against fatigue and sleepiness, which both impact patient safety. However, there is insufficient evidence on how nurses nap, especially concerning their napping quality. …”
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Prevalence of cardiovascular symptoms in post-acute COVID-19 syndrome: a meta-analysis by Li-wei Huang, Hua-min Li, Bei He, Xiao-bo Wang, Qi-zhi Zhang, Wen-xing Peng

“…Emerging evidence indicates that COVID-19 may lead to post-acute COVID-19 syndrome (PACS) with cardiovascular implications, potentially driven by factors such as ACE2 interaction with viruses, systemic inflammation, and endothelial dysfunction. However, there remains a limited amount of research on the cardiovascular manifestations of PACS, which may delay the development of optimal treatment strategies for affected patients. …”
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Association between Air Pollution and Risk of Hospital Admission for Pediatric Pneumonia in a Tropical City, Kaohsiung, Taiwan by Peng-Huei Liu, Kuo-Chen Huang, Yu-Lun Tseng, I-Min Chiu, Hsiu-Yung Pan, Fu-Jen Cheng

“…Abstract Recent evidences have shown that particulate matter (PM) and other air pollutants are associated with pulmonary and systemic inflammation; however, the relationship between air pollutants and the risk of admission for pediatric pneumonia has not been well surveyed. …”
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Lifestyle risk factors for overweight and obesity among rural Indian adults: a community-based prospective cohort study by Rajesh Kumar Rai, Sabri Bromage, Jan-Walter De Neve, Anamitra Barik

“…India’s nutrition transition has led to an increased burden of overweight/obesity (body mass index of ≥23 kg/m2), driven by lifestyle factors like poor diet, inactivity, and substance use, prompting public health interventions. However, these interventions lack supporting evidence, especially in rural areas, hindering effective strategies for this population. …”
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Assessment of vegetation in Murchison falls national park five years after the completion of oil and gas exploration by Hindrah Akisiimire, William Tinzaara, Keneth Tumwebaze, Charles K.Twesigye

“…The results of vegetation relative abundance and diversity between oil pads and control areas were generally similar. However, the study observed some plant species such as Desert date (Balanites aegyptiaca) in control areas that were completely absent in oil pads. …”
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Potentially traumatic childbirth experience, childbirth-related post-traumatic stress disorder symptoms, and the parent-infant relationship in non-birthing parents by Rebecca Hunter, Leonardo De Pascalis, Kieran Anders, Pauline Slade

“…Non-birthing parents who experienced birth as potentially traumatic reported significantly higher CB-PTSD symptoms and felt a greater sense of invasion in relation to their infant. However, levels of warmth in the parent-infant relationship were not statistically different between the two groups. …”
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Community perceptions of community health worker effectiveness: Contributions to health behaviour change in an urban health district in South Africa by L S Thomas, Y Pillay, E Buch

“…Community health worker (CHW) programmes contribute towards strengthening adherence support, improving maternal and child health outcomes and providing support for social services. They play a valuable role in health behaviour change in vulnerable communities. …”
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