TAp63γ is the primary isoform of TP63 for tumor suppression but not development by Xinbin Chen, Wenqiang Sun, Xiangmudong Kong, Xin Ming, Yanhong Zhang, Wensheng Yan, Shakur Mohibi, Mingyi Chen, Keith Mitchell, Jin Zhang

“…By contrast, ΔNp63α, which also contains an N-terminal activation domain but is different from that in TAp63, regulates a unique set of genes and functions as a master regulator for development of epidermis and other stratified epithelial tissues. However, the biological function of p63γ is largely unexplored. …”
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Gender-transformative HIV and SRHR programme approaches for adolescents and young people: a realist review to inform policy and programmes by Isolde Birdthistle, Annabelle Gourlay, Sagri Singh, Damilola Walker, Migena Mata

“…This bodes well for empowering strategies to achieve HIV and STI reduction targets among adolescents and young people, and broader SRH goals. However, most interventions prioritise individual rather than structural change; impeding their ‘gender transformative’ potential.…”
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Prevalence and associated factors of psychological distress among caregivers of children with malnutrition: a cross‑sectional study by Biazin Yenealem Mekuriaw, Berhanie Getnet, Endris Seid, Tadese Teferi, Amare Alemwork, Mastewal Aschale, Aklile Tsega

“…Studies have shown that psychological distress has an impact on infant growth and nutritional status. However, evidence regarding the relationship between psychological distress and child malnutrition is scarce. …”
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Accidental findings of maxillary sinuses in dental patients on CBCT images. A retrospective study by Fedil Andraws Yalda

“…The findings of the present study recommend a thorough interpretation of the whole volume CBCT scans, by an oral radiologist, to ensure a proper diagnosis as it might have an impact on the patient’s medical status and advice the referred practitioner about the findings which may affect the treatment plan accord[1]ingly. …”
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Breast cancer risk assessment based on a predictive model: evaluation of risk factors among Japanese women by Michiyo Yamada, Takashi Chishima, Takashi Ishikawa, Kazutaka Narui, Sadatoshi Sugae, Peter J. Tonellato, Itaru Endo

“…Abstract Background Each breast cancer (BC) risk factor has different effects on different populations. However, there are no well-studied and validated BC risk prediction models for Japanese women. …”
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Comparing Health Care Financing in Indonesia and Thailand from 1995-2010: What Lessons Could Be Learned? by Darius Erlangga, Lizheng Shi

“…**Results:** In comparing the health financing of the two countries, we found that Thailand initiated much earlier health systems reforms in order to achieve universal health coverage. Indonesia, while on the right track, has moved at a slower pace than Thailand. …”
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Association between exposure to perfluoroalkyl and polyfluoroalkyl substances with estimated glomerular filtration rate: Mediating role of serum albumin by Hua Fang, Huajing Chang, Danjing Chen, Wenxin Qiu, Jiangwang Fang, Yunli Wu, Xian-E. Peng

“…Background: Previous studies have demonstrated perfluoroalkyl and polyfluoroalkyl substances (PFAS) impact renal function, with albumin playing dominant role in their transport and accumulation. However, the mediating role of albumin in PFAS-induced renal impairment and the identification of sensitive populations remain uninvestigated. …”
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Association between Chinese visceral adiposity index and risk of new-onset hypertension in middle-aged and older adults with prediabetes: evidence from a large national cohort stud... by Lanlan Li, Lanlan Li, Linqiang Xi, Qianhui Wang

“…PurposeChinese Visceral Adiposity Index (CVAI) has been found significantly associated with hypertension in general and type-2 diabetes adults. However, the predictive value of CVAI for the incidence of hypertension in adults with prediabetes is unclear. …”
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Evaluation of three remineralizing agents on surface roughness of enamel. by Vian O. Majeed, Hemn M. Sarmamy, Rebin A. Mohammedamin

“…The results showed that both Group 4 (GC, MI paste) and Group 2 (Mouth wash) group had a significant effect on the surface roughness when compared to other two groups. However, the remineralizing effect of Group 1 (Kin toothpaste) and control group were not significant. …”
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Clinical outcomes after immune checkpoint inhibitor-associated acute kidney injury: a cohort study by Vin-Cent Wu, Ting-Ya Yang, Min-Hsiang Chuang, Hong-Min Lin, Heng-Chih Pan, Yun Chou, Jui-Yi Chen

“…Objectives Immune checkpoint inhibitors (ICPi) have significantly improved survival for patients with advanced cancers. However, the occurrence of ICPi-associated acute kidney injury (AKI) and its clinical impact remains unclear. …”
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Trends, gender, and racial disparities in patients with mortality due to paroxysmal tachycardia: A nationwide analysis from 1999-2020. by Aman Goyal, Humza Saeed, Saif Yamin, Abdullah, Wania Sultan, Muhammad Khubaib Arshad, Samia Aziz Sulaiman, Mah I Kan Changez, Gauranga Mahalwar

“…<h4>Conclusions</h4>Our analysis showed a significant decrease in mortality from paroxysmal tachycardia since 1999, although there has been a slight increase in recent years. However, disparities remain, with higher AAMRs among men, NH Black or African Americans, and residents of non-metropolitan areas. …”
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Racial and ethnic disparities in longitudinal trajectories of cardiovascular risk factors in U.S. middle-aged and older adults. by Matthew E Dupre, Radha Dhingra, Hanzhang Xu, Scott M Lynch, Qing Yang, Cassie Ford, Michael D Green, Ying Xian, Ann Marie Navar, Eric D Peterson

“…<h4>Background</h4>Racial and ethnic disparities in cardiovascular disease (CVD) risk factors are well-documented. However, racial and ethnic differences in the longitudinal changes among multiple CVD risk factors are unknown.…”
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Analisis Metode Cosine Similarity Pada Aplikasi Ujian Online Otomatis (Studi Kasus JTI POLINEMA) by Eka Larasati Amalia, Angelita Justien Jumadi, Irsyad Arif Mashudi, Dimas Wahyu Wibowo

“…In order not to take a lot of time to correct student answers, the system has an assessment of the similarity of answers for the assessment. …”
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The association between pretransplant malignancy and post-transplant survival and cancer recurrence in bilateral lung transplantation: An analysis of 23,291 recipients by Wongi Woo, MD, Hye Sung Kim, MD, Ankit Bharat, MBBS, Young Kwang Chae, MD, PhD, MBA

“…Compared to those without pre-TM, patients with pre-TM had worse overall (hazard ratio [HR] 1.20, 95% confidence interval [CI] 1.12-1.29, p < 0.001) and post-TM-free survival (HR 1.32, 95% CI 1.24-1.41, p < 0.001). However, after adjusting for age, sex, and race through propensity score matching, the survival difference between the groups became nonsignificant (HR 1.05, 95% CI 0.97-1.13, p = 0.229). …”
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The efficacy of sodium-glucose transporter 2 inhibitors in patients with nonalcoholic fatty liver disease: A systematic review and meta-analysis by Hongsheng Li, Yanli Hou, Wenyong Xin, Lina Ding, Ying Yang, Yikun Zhang, Wenqi Wu, Zhibin Wang, Wenyu Ding

“…SGLT-2 inhibitors intervention was also associated with significant reductions in body weight (MD [95 % CI]; −2.72 kg [-3.49, −1.95], p < 0.00001) and BMI (MD [95 % CI]; −1.11 kg/m2 [-1.39, −0.82], p < 0.00001) and improvements in glycaemic indices, triglyceride (TG) and high-density lipoprotein cholesterol (HDL-C). However, no significant changes in total cholesterol (TC) or low-density lipoprotein cholesterol (LDL-C) were observed. …”
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Determinants of minimum meal frequency among children in Kumbungu District of Ghana: a cross-sectional study by Ambrose Atosona, Hidaya Abdul Wahab, Fuseini Alhassan, Mildred Donkoh, Michael Akenteng Wiafe, Clement Kubreziga Kubuga

“…Ensuring a child’s minimum meal frequency is met is critical for preventing malnutrition and improving nutrient intake. However, minimum meal frequency and its context-specific determinants among children in the Kumbungu District of Ghana are yet to be investigated. …”
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PTEN suppresses renal cell carcinoma proliferation and migration via inhibition of the PI3K/AKT pathway by Xu Xu, Yuan-Yue Tang, Xiaohong Liang, Wen Luo, Dong-Mei Jiang, Jie Chen

“…Objective This article was recruited to examine the PTEN’s role in managing the PI3K/AKT pathway and its impact on the RCC cell proliferation and migration. …”
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Assessing the impact on mode competitiveness of improvements of the Trans-Eurasian railway network by Seyed Mohseni, Edwin van Hassel, Thierry Vanelslander

“…It can be observed that also the transport on the Eurasian connection has been growing, especially by rail. However, by far the largest volumes of transport still happen by maritime transport. …”
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Profile of non-invasive physical health indicators associated with cognitive performance in Chinese older adults: evidence from the China Health and Retirement Longitudinal Study by Xiyu Wei, Chao Li, Dongyu Liu, Jieyi Chen, Yumeng Ju, Jin Liu, Bangshan Liu, Yan Zhang

“…Abstract Background Existing studies have indicated the potential role of non-invasive physical health indicators as an early detector of mild cognitive impairment (MCI) in older adults. …”
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Metatranscriptomes-based sequence similarity networks uncover genetic signatures within parasitic freshwater microbial eukaryotes by Arthur Monjot, Jérémy Rousseau, Lucie Bittner, Cécile Lepère

“…Their taxonomic and functional diversity are increasingly well described due to recent advances in sequencing technologies. However, the vast amount of data produced by -omics approaches require data-driven methodologies to make predictions about these microorganisms’ role within ecosystems. …”
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