Exploring the multi-targeted mechanism of Saikosaponin A in prostate cancer treatment: a network pharmacology and molecular docking approach by Genbao Zhu, Genbao Zhu, Genbao Zhu, Zhiming Jiang, Niuping Zhu, Niuping Zhu, Donghui Wang, Donghui Wang, Tianpeng Guo, Tianpeng Guo, Yiqing Meng, Yiqing Meng, Yi Zhu, Yi Zhu, Kemeng Tan, Mengxue Hu, Heng Tang, Xuannian Wang, Xuannian Wang

“…Finally, SSA also induced G1-phase blockade and apoptosis in PC3 cells, further highlighting its potential role in prostate cancer treatment.ConclusionThe present study revealed that SSA exerts anti-tumorigenic effects in prostate cancer by targeting multiple pathways, laying a theoretical reference for its use as a therapeutic candidate for prostate cancer.…”
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Implementation of a rapid host-protein diagnostic test for distinguishing bacterial and viral infections in adults presenting to urgent care centers: a pragmatic cohort study by Boaz Kalmovich, Daniella Rahamim-Cohen, Ilan Yehoshua, Sara Kivity, Noam Orvieto, Shirley Shapiro Ben David

“…Methods A pragmatic prospective cohort study. Physicians who ordered MMBV reported electronically (in real-time) whether they intended to prescribe antibiotics before ordering the test and upon UCC discharge whether MMBV aided in patient management. …”
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An intelligent lithology identification method for sandstone and mudstone strata and its applications: A case study of the Jurassic strata in the Lunnan area, Xinjiang, China by Ming CAI, Qingwen ZHOU, Cong YANG, Feng CHEN, Dong WU, Wang LIN, Chengguang ZHANG, Yuanjun ZHANG, Yuxin MIAO

“…Besides, these results can serve as a valuable reference for research on methods for fine-scale identification of complex lithologies.…”
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Hyssopus cuspidatus volatile oil: a potential treatment for steroid-resistant asthma via inhibition of neutrophil extracellular traps by Xu Wang, Hui-Ming Peng, Meng-Ru Zhang, Jing-Jing Li, Chuan-Peng Zhao, Ya-Li Zhang, Si-Yu Wang, Si-Ying Zhu, Jian-Kang Lu, Hai-Long Yin, Qiang Yin, Jin-Bo Fang

“…., a traditional Uyghur medicine, is known for its efficacy in treating inflammatory lung conditions such as asthma. However, the therapeutic impact and underlying mechanisms of Hyssopus cuspidatus Boriss.’s volatile oil (HVO) in SRA have not been fully elucidated. …”
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GIOS ONLINE PLATFORM AS A TOOL FOR OVERCOMING LEARNING LOSSES IN MATHEMATICS by Daryna V. Vasylieva, Tetiana L. Hodovaniuk

“…It is noted that in order to help their students overcome learning losses, teachers should either develop mathematics materials independently or use ready-made materials. …”
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Progress in prediction of photocatalytic CO2 reduction using machine learning approach: A mini review by Md Mohshin Ali, Md. Arif Hossen, Azrina Abd Aziz

“…Emerging Machine learning (ML) techniques have significantly improved the predictive performance and operational efficiency of photocatalytic systems. These models can handle extensive experimental datasets, optimize operational parameters, and provide insights into CO2 reduction (CO2R) mechanisms. …”
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Comparison of Birth Weights of Pre-Delivery Anemic and Non-Anemic Routine Iron Supplemented Pregnant Women by Tolga Atakul

“…There was no significant association between pre-delivery anemia and birth weight. However, the anemic women group was found to be slightly younger than non-anemic ones according to both criteria. …”
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Intestinal Microbiota in Patients with Chronic Heart Failure and Systolic Dysfunction by M. V. Fadeeva, A. V. Kudryavtseva, G. S. Krasnov, M. R. Skhirtladze, V. T. Ivashkin

“…No dependence of the intestinal microflora composition on the functional class of heart failure was observed. However, a correlation was revealed between the relative number of certain bacterial families and the severity of impaired contractile function, the level of the inflammatory marker and the biochemical marker of heart failure.Conclusions. …”
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Early Iron Age Pottery Technology of the Kazakh Uplands (Saryarqa) by Valeriy G. Loman

“…The investigated settlements of Central and North Kazakhstan are characterized by that they would mainly select similar raw material — medium-iron clays. However, the pottery paste recipes did differ: in North Kazakhstan, preference was given to medium-size mineral tempers, and to larger ones — in Central Kazakhstan. …”
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CAUSAL RELATIONSHIP AMONGST CORPORATE LONG-TERM FINANCING DECISIONS: EMPIRICAL EVIDENCE OF LISTED NIGERIAN MANUFACTURING FIRMS by Jeremiah Babajide OPALEKE

“…The trio of capital investment, financing and dividend payout is the study’s dependent and controllable variables, which are measured by the sampled firms’ fixed assets; addition of equities and debts; and the declared dividend payments for the periods covered respectively. The data employed were of unbalanced panel that is purely secondary. …”
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Sex differences in the neuroinflammatory signaling pathway: effect of miRNAs on fatty acid synthesis in microglia by Haolin Zheng, Akiko Mizokami, Sergio Romera-Giner, Jaime Llera-Oyola, Yosuke Yamawaki, Tomomi Sano, Eijiro Jimi, Francisco García-García, Takashi Kanematsu

“…Recent studies have demonstrated that microglia, the primary innate immune cells in the brain, play a crucial role in AD development. Therefore, this study aimed to explore sex differences in microglial function, specifically focusing on the role of testosterone in miRNA-mediated regulation of microglial gene expression. …”
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Coupling effect of landscape patterns on the spatial and temporal distribution of ecosystem services: a case study in Harbin City, Northeast China by Yuxin Qi, Peixin Shen, Shu Ren, Tianyi Chen, Yuandong Hu

“…Abstract To secure the enduring the long-term growth of ecosystem services, the city of Harbin in northeastern China must prioritize the optimization of its landscape pattern. However, there is a dearth of studies pertaining to the geospatial repercussions of landscape patterns on ecosystem services. …”
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Comparison of Patent Foramen Ovale Sizing by Transesophageal Echocardiography and Balloon Sizing in Patients Undergoing Percutaneous Closure by Birgitte Carbuhn Larsen, MD, Martin Christian Harmsen, MD, Henrik Vase, MD, PhD, Jens Erik Nielsen-Kudsk, MD, DMSc, Asger Andersen, MD, PhD

“…However, a difference was observed between a small and large PFO shunt size. …”
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Double Cerclage In Cervical Insufficiency: A Single Tertiary Center Experience by Ismet Hortu, Cagdas Sahin, Orkun Ilgen, Mert Kazandi, Ali Akdemir, A. Mete Ergenoglu

“…Conclusion: Laparoscopic cervical cerclage during pregnancy could be a safe and effective treatment. However, sometimes it might not be enough and transvaginal cervical cerclage may be needed to strengthen cervical tension. …”
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Increased Risk of Influenza-Like Illness Clusters in Schools, Taiwan from 2011 to 2020: A Retrospective Study by Yu-Ching Chou, Fu-Huang Lin, Chi-Jeng Hsieh, Chia-Peng Yu

“…This study provides valuable insights into ILI cluster transmission patterns in Taiwan over a 10-year period and highlights the importance of long-term studies covering a wide geographic area as a means of understanding the implications of such patterns.…”
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Data analysis for performance index of plate heat exchanger filled by ionanofluid-oil: parallel versus counterflow by Ishrat Zahan, Rehena Nasrin, Nusrat Jahan Jakia

“…Innovations in this area significantly improve energy efficiency, reduce environmental impact, and enhance industrial processes. However, the ionanofluid significantly enhanced the thermal conductivity and heat transfer coefficient compared to conventional fluids. …”
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Kaempferol protects against high-salt-induced hypertension and vascular endothelial injury by inhibiting ferroptosis through the ATF4/ACSL4 pathway by Qiuer Liang, Minghao Chen, Guangtian Chen, Pengli Xu, Lai Kwan Lam, Pengcheng Xie, Ting Xie, Wanqing Tu, Tianhao Liu, Xiaopeng Peng, Haoyao Yuan, Liguo Chen, Ya Xiao

“…Kaempferol (Kae), a natural flavonol belonging to the flavonoid family, has demonstrated significant vascular protective effects in previous studies. However, its impact on high-salt-induced hypertensive vascular injury remains unclear. …”
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Improving The Performance of Big Data Databases by Nzar Abdulqadir Ali, Dashne Raouf Arif

“…In SQL (Structured Query Language) databases different algorithms are used for inserting and updating data, such as indexing, bulk insert and multiple updating. However, in NoSQL different algorithms are used for inserting and updating operations such as default-indexing, batch insert, multiple updating and pipeline aggregation. …”
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Effectiveness of aspirin in preventing deep vein thrombosis following proximal femoral fracture surgery in Japan by Takao Ohmori, Kazukiyo Toda, Takuya Taoka, Takeshi Ishihara, Yasuo Ito

“…Consequently, aspirin is not covered by insurance for the prevention of venous thrombosis. …”
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The library of Troškūnai monastery by Arvydas Pacevičius

“…The Library of the Troškūnai cloister was modern, as more than 90 percent of the collection consisted of 18th-century issues; on the other hand, it reflected the increasing role of books in Lithuanian society during this period. …”
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