IFN-γ reprograms cardiac microvascular endothelial cells to mediate doxorubicin transport and influences the sensitivity of mice to doxorubicin-induced cardiotoxicity by Haoyu Ji, Wenya Ma, Xu Liu, Hongyang Chen, Yining Liu, Zhongyu Ren, Daohong Yin, Ao Cai, Zizhen Zhang, Xin Wang, Wei Huang, Leping Shi, Yanan Tian, Yang Yu, Xiuxiu Wang, Yang Li, Yu Liu, Benzhi Cai

“…DIC-insensitive mice displayed preserved ejection fractions, lower DOX levels in cardiac tissues and higher levels in the serum. …”
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Rapid literature mapping on the recent use of machine learning for wildlife imagery by Nakagawa, Shinichi, Lagisz, Malgorzata, Francis, Roxane, Tam, Jessica, Li, Xun, Elphinstone, Andrew, Jordan, Neil R., O'Brien, Justine K., Pitcher, Benjamin J., Van Sluys, Monique, Sowmya, Arcot, Kingsford, Richard T.

“…There were relatively few collaborations across countries. Given the power of machine learning, we recommend increasing collaboration and sharing approaches to utilise increasing amounts of wildlife imagery more rapidly and transform and improve understanding of wildlife behaviour and conservation. …”
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Early Postoperative Safety of Total Hip Arthroplasty in Systemic Lupus Erythematosus Patients by YANG Xingdong, YU Muyang, XU Yiming, ZHU Wei, HU Mingwei, WENG Xisheng, FENG Bin

“…After propensity score matching, 163 cases from SLE and control groups were included for analysis. (1) Regarding medical complications, compared with control group, SLE group showed significant differences in osteoporosis, respiratory system disorders, gastrointestinal diseases, urinary system disorders, hematologic abnormalities, and secondary or concomitant rheumatic diseases (all P < 0.05). (2) In terms of preoperative laboratory tests, SLE group had lower platelet counts, absolute lymphocyte counts, hemoglobin levels, hematocrit, albumin levels, blood glucose levels, and activated partial thromboplastin times than control group, while C-reactive protein, erythrocyte sedimentation rate, and D-dimer levels were higher (all P < 0.05). (3) Regarding surgical-related indicators, a higher proportion of patients in SLE group had an ASA grade > 2 (15.95% vs. 3.07%, P < 0.001), but intraoperative blood loss was significantly smaller [324.7 (200.0, 500.0) mL vs. 421.8 (200.0, 500.0) mL, P=0.005]. (4) In terms of complications, SLE group exhibited a significantly higher incidence of major complications than control group (8.59% vs. 1.23%, P=0.005), with a relative risk of 1.081 (95% CI: 1.028-1.136). …”
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Impact of donor CYP3A5 genotype on pharmacokinetics of tacrolimus in South African paediatric liver transplant patients by C Wheeler, C Masimirembwa, B Mthembu, J Botha, J Scholefield, J Fabian

“…During the first 15 days post-transplant, we found that children who received grafts from donor CYP3A5 expressors (CYP3A5*1/*1 and *1/*3) had significantly lower mean tacrolimus CDRs compared with those who received grafts from donor CYP3A5 non-expressors (*3/*3); the recipients of CYP3A5 expressor grafts therefore require higher doses of oral tacrolimus to achieve the same therapeutic target range. …”
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Balancing selection at a wing pattern locus is associated with major shifts in genome-wide patterns of diversity and gene flow by Rodríguez de Cara, María Ángeles, Jay, Paul, Rougemont, Quentin, Chouteau, Mathieu, Whibley, Annabel, Huber, Barbara, Piron-Prunier, Florence, Ramos, Renato Rogner, Freitas, André V. L., Salazar, Camilo, Silva-Brandão, Karina Lucas, Torres, Tatiana Teixeira, Joron, Mathieu

“…By contrast, monomorphic populations of H. numata as well as its sister species and their ancestral lineages all show lower effective population sizes and genetic diversity, and higher levels of geographical structure across the continent. …”
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Role of 18F-PSMA-1007 PET/CT-derived quantitative volumetric tumor parameters in cytoreductive radical prostatectomy selection for patients with low-volume metastatic hormone-sensitive prostate cancer: a retrospective study by Junjie Fan, Ke Xu, Zhangdong Jiang, Chaosheng Gan, Hao Song, Guoqiang Gao, Guojing Wang, Qiyuan Kang, Liang Luo, Zhuonan Wang, Dalin He, XiaoYi Duan, Kaijie Wu

“…Cox regression analyses revealed that cRP, lower whole-body PSMA-TV and the absence of NRLN metastases were associated with better PFS (all P < 0.05). …”
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Reproductive modes in populations of late-acting self-incompatible and self-compatible polyploid Ludwigia grandiflora subsp. hexapetala in western Europe by Stoeckel, Solenn, Becheler, Ronan, Portillo-Lemus, Luis, Harang, Marilyne, Besnard, Anne-Laure, Lassalle, Gilles, Causse-Védrines, Romain, Michon-Coudouel, Sophie, Park, Daniel J., Pope, Bernard J., Petit, Eric J., Barloy, Dominique

“…Within the 53 studied populations, the 13 short-styled populations had fewer effective alleles, lower observed heterozygosity, and higher inbreeding coefficients, linkage disequilibrium and estimates of selfing than what was found in long-styled populations. …”
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How mechanochemistry affects the composition and properties of disordered fluorite BaSnF4? by Mercadier, Briséïs, Legein, Christophe, Duttine, Mathieu, Body, Monique, Gutierrez, Ana Gabriela Porras, Leclerc, Sandrine, Lebedev, Oleg,  Masquelier, Christian, Dambournet, Damien

“…Such a hypothesis is supported by the occurrence of fluoride ions located within octahedral sites, which are likely to be bound to Sn(IV) resulting to their lower mobility as shown by 19F solid-state NMR. Overall, this work demonstrates that the interplay between the microstructure, composition and the transport properties of fluoride ion conductors is indeed complex, with many factors at play, including size, strain, defects or composition.…”
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Implementing adaptive e-learning for newborn care in Tanzania: an observational study of provider engagement and knowledge gains by Peter Andrew Meaney, Christine Lynn Joyce, Ambrose Agweyu, Joseph R Mwanga, Marc Berg, Adolfine Hokororo, Hanston Ndosi, Alex Dahlen, Theopista Jacob, Florence Salvatory Kalabamu, Rishi Mediratta, Boris Rozenfeld, Zachary Haines Smith, Neema Chami, Namala Mkopi, Castory Mwanga, Enock Diocles

“…Providers were often unaware of knowledge gaps, and lower baseline knowledge may decrease initial learning completion or activity. …”
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Phase I clinical trial testing the dose escalation and expansion of Pressurized IntraThoracic Hyperthermic Aerosol Cisplatin administration (PITHAC) for the management of pleural c... by Louis-Emmanuel Chriqui, Etienne Abdelnour-Berchtold, Edoardo Zanfrini, Severine Devesa-Perez, Michel Gonzalez, Thorsten Krueger, Kim Ellefsen, Alice Destaillats, David Bonnet, Martin Hübner, Hasna Bouchaab, Michal Bassani-Sternberg, Solange Peters, Sabrina Cavin, Jean Y Perentes

“…The primary endpoint is the maximal tolerated dose of cisplatin administered by PITHAC. …”
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Economic-productive analysis of a mixed cattle-bubaline model mixed model in the Northern region of Corrientes Province in Argentina by Pablo Maldonado-Vargas, Vanesa Guadalupe Mierke, Liliana Laura Pellerano, Guillermo Sebastián Grimaldi, Orlando Alberto Álvarez, Natalia Mercedes Vallejos, Margarita Rosa Itatí Romero, Francisco Daniel Romero, Alexis Sebastián Bandeo, Gonzalo Enrique Tuñón, José Luis Konrad

“…In this way, it will be possible to participate more actively in the formation of prices, partially reversing the power of the current market, focusing on adding value and receiving a price premium for what has been done, generating extra income in buffalo production systems as a livestock activity. …”
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Long-term trends and patterns in ultra-processed food consumption among Korean adults from 1998 to 2022 by Hyeseung Lee, Yesol Yim, Yerin Cho, Jiyeon Oh, Soeun Kim, Yejun Son, Hyesu Jo, Seohyun Hong, Masoud Rahmati, Hanseul Cho, Jiyoung Hwang, Dong Keon Yon

“…In 2020–2022, ultra-processed foods had a higher proportion of calories from carbohydrates (62.12% vs. 58.81%) and fats (28.22% vs. 22.31%) but a lower proportion from protein (10.32% vs. 17.26%) compared to non-ultra-processed foods. …”
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Improved SED-fitting Assumptions Result in Inside-out Quenching at z ~ 0.5 and Quenching at All Radii Simultaneously at z ~ 1 by Alexander de la Vega, Susan A. Kassin, Camilla Pacifici, Stéphane Charlot, Emma Curtis-Lake, Jacopo Chevallard, Timothy M. Heckman, Anton M. Koekemoer, Weichen Wang

“…Their slopes are similar at all masses (0.06–0.08 dex kpc ^−1 ), and the normalizations for the quiescent galaxies are lower. Therefore, the sSFR profiles decline with time as quenching occurs at all radii simultaneously. …”
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Single-nucleotide polymorphisms in dizygotic twin ovine fetuses are associated with discordant responses to antenatal steroid therapy by Erin L. Fee, Haruo Usuda, Sean W. D. Carter, Hideyuki Ikeda, Tsukasa Takahashi, Yuki Takahashi, Yusaku Kumagai, Michael W. Clarke, Demelza J. Ireland, John P. Newnham, Masatoshi Saito, Sebastian E. Illanes, Binny Priya Sesurajan, Liang Shen, Mahesh A. Choolani, Gokce Oguz, Adaikalavan Ramasamy, Sara Ritchie, Andrew Ritchie, Alan H. Jobe, Matthew W. Kemp

“…These data suggest a potential heritable role in determining ANS responsiveness.…”
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Straw return combined with water-saving irrigation increases microbial necromass accumulation by accelerating microbial growth-turnover in Mollisols of paddy fields by Peng Chen, Junzeng Xu, Kechun Wang, Zhongxue Zhang, Zhaoqiang Zhou, Yawei Li, Tiecheng Li, Tangzhe Nie, Qi Wei, Linxian Liao

“…The CI-SR treatment strengthened microbial roles in Mollisols paddy fields by enhancing the net flux of microbial biomass formation, and consequently promoting the incorporation of greater amounts of microbial-derived C in the SOC pool.…”
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Incidence and temporal trends of out-of-hospital cardiac arrest in Shenzhen, China (2011–2018) by Hong Zhu, Junpeng Liu, Tianqi Yang, Yan Zhang, Yanjun Xu, Yunfeng Xu, Hao Wu, Li Li, Yufeng Luo, Cai Wen, Tao Yu

“…Conclusions: OHCA incidence in Shenzhen is lower than both domestic and international levels but increasing. …”
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Perbandingan Metode Supervised Machine Learning untuk Prediksi Prevalensi Stunting di Provinsi Jawa Timur by M Syauqi Haris, Ahsanun Naseh Khudori, Wahyu Teja Kusuma

“…The support vector regression method in this study has a lower error value, namely 0.91 for MAE and 1.30 for MSE. …”
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Lipids as key biomarkers in unravelling the pathophysiology of obesity-related metabolic dysregulation by Anis Adibah Osman, Siok-Fong Chin, Lay-Kek Teh, Noraidatulakma Abdullah, Nor Azian Abdul Murad, Rahman Jamal

“…A stepwise logistic regression revealed three metabolites associated with increased risk of obesity (14-methylheptadecanoic acid, 4′-apo-beta,psi-caroten-4'al and 6E,9E-octadecadienoic acid), and three with lower risk of obesity (19:0(11Me), 7,8-Dihydro-3b,6a-dihydroxy-alpha-ionol 9-[apiosyl-(1->6)-glucoside] and 4Z-Decenyl acetate). …”
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Sedentary Behavior and Its Association With Psychological Well-Being and Sleep Quality in Adolescents: Evidence from a Propensity Score Analysis by Zhang L, Zhao S, Zhao S, Zheng H, Ke Y, Yang W, Lei M

“…Participants with sedentary lifestyles exhibited higher scores on the GAD-7 (P< 0.001), PHQ-9 (P< 0.001), and PSQI (P< 0.001), along with lower self-esteem (SES, P=0.041) and social support (SSRS, P< 0.001) compared to their more active counterparts. …”
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Sistem Informasi Geografis Penyebaran Usaha Mikro Kecil Menengah (UMKM) di Kabupaten Majalengka by Muhammad Darul Husni Santoso, Ikbal Jamaludin, Evi Dewi Sri Mulyani

“…With the development of Micro, Small and Medium Enterprises (MSMEs) in Majalengka Regency, it can move the community's economy, especially in the lower sector, namely for micro small and medium businesses. …”
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