PRICING EMPLOYEE STOCK OPTION USING TRINOMIAL TREE METHOD by Donny Citra Lesmana, Reza Tri Ahmad Ramadhan, Siti Nurjanah, Vanaya Syahira Dharmawan

“…This study explores the Employee Stock Option (ESO) model proposed by Liao and Lyuu, which provides a robust framework for addressing critical factors such as dilution, early exercise, and employee forfeiture rates. …”
Get full text

Modeling of various life processes of <i>Juniperus excelsa</i> M. Bieb to determine optimal growing conditions in the southern coast of Crimea, Russia by A. V. Pashtetsky, O. A. Ilnitsky

“…Modeling and smoothing of two‐dimensional data was carried out using the least squares method, robust locally weighted regression and a mathematical model of stepwise regression analysis.Results. …”
Get full text

T lymphocyte-targeted immune checkpoint modulation in glioma by Mark Gilbert, William James Kelly, Amber Jin Giles

“…Although initial clinical results in patients with glioblastoma (GBM) were disappointing, recently published results have demonstrated a potential survival benefit in patients with recurrent GBM treated with neoadjuvant programmed cell death protein 1 blockade. While these findings necessitate verification in subsequent studies, they support the possibility of achieving clinical meaningful immune responses in malignant primary brain tumors including GBM, a disease in dire need of additional therapeutic options. …”
Get full text

Overview of Computational Toxicology Methods Applied in Drug and Green Chemical Discovery by Jose I. Bueso-Bordils, Gerardo M. Antón-Fos, Rafael Martín-Algarra, Pedro A. Alemán-López

“…It is advantageous to perform virtual predictions as early as possible in drug development processes, even before a molecule is synthesized. …”
Get full text

Le port romain du quartier de Saint-Lupien à Rezé/Ratiatum (Loire-Atlantique) : origine et évolution by Jimmy Mouchard, David Guitton, Martial Monteil, Xavier Favreau, Nicolas Ménez, Matthieu Yacger

“…These structures, which served as docks along the riverbank of the main river bed, present a mixed framework, consisting of wood and stone, specifically a very elaborate and robust oak frame, including half-timbered facades and significant dry-stone filling. …”
Get full text

Velocity-Constraint Kalman Filtering for Enhanced Bubble Tracking in Motion-Compensated Ultrasound Localization Microscopy by Yifei Zhu, Lingyin Jiang, Qi Zhang, Jun Yin, Bingze Du, Guofeng Zhang, Haijun Zhang, Bo Ding, Han Lin, Honghui Xue, Xiasheng Guo, Xiao-Yang Zhang, Jing-Ning Zhu, Dong Zhang, Juan Tu, Ning Gu

“…More important, to effectively suppress the impact of physiological movements in moving organs like kidneys, this algorithm fulfilled subpixel displacement vector identification through parabolic fitting and expedited motion compensation via dynamic programming-based cross-correlation search. The results indicated that this advanced vc-Kalman method substantially boosted both the robustness and accuracy of ULM imaging, thereby opening more opportunities for clinical applications of super-resolution ULM technology.…”
Get full text

Childhood predictors of charitable giving and helping across 22 countries in the Global Flourishing Study by Julia S. Nakamura, Robert D. Woodberry, Dorota Weziak-Bialowolska, Laura D. Kubzansky, Koichiro Shiba, R. Noah Padgett, Byron R. Johnson, Tyler J. VanderWeele

Get full text

Calculating Required Purification Effort to Turn Source Water Into Drinking Water Using an Adapted CCME Water Quality Index by André van denDoel, Geert H. vanKollenburg, Thomas D. N. vanRemmen, Joanne A. deJonge, Geert J. Postma, Gerjen H. Tinnevelt, Gerard J. Stroomberg, Lutgarde M. C. Buydens, Jeroen J. Jansen

“…Our WQI compares measured contaminant concentrations in source water to drinking water guidelines and any exceedance is weighted by a measure of the resilience of that contaminant to the treatment processes, which is not possible in the CCME WQI. Furthermore, it accommodates for varying sampling frequencies that are characteristic of the ongoing monitoring program. …”
Get full text

Interventions to Improve Connectedness, Belonging, and Engagement in Secondary Schools: A Systematic Review and Meta-Analysis by Caleb Anson Davies, Reinie Cordier, Pamela Graham, David Littlefair, Renée Speyer, Diego Melo

“…Overall, interventions significantly improved connectedness, belonging, and engagement (Hedges’ <i>g</i> = 1.056, within-group; 0.642, between-group). Multi-tier programs yielded the largest effects (0.781), with ecological (0.613) and environmental (0.636) approaches; behavioural and intrapersonal strategies were non-significant, possibly due to the small sample sizes. …”
Get full text

Evaluating Inter-Rater Reliability: Transitioning to a Single Rater for Marking Modified Essay Questions in Undergraduate Medical Education by Shahid Hassan, Malanashita Ganeson, Ismail Abdul Sattar Burud

“…Current study explores the possibility of assigning a single assessor to mark the students' performances in MEQ based on statistically drawn evidence in the clinical phase of the MBBS program at a private medical school in Malaysia. …”
Get full text

Integrating human biomonitoring exposure data into a primary care morbidity database: a feasibility study by Pieter Jansen, Elly Den Hond, Katleen De Brouwere, Endale Alemayehu Ali, Hamid Yimam Hassen, Ilona Gabaret, Gijs Van Pottelbergh

“…However, with PFAS data from more than 10,000 residents available soon, more robust studies will be possible with this new method. …”
Get full text

Innovative aspects of customer relationship management in an ecosystem marketing environment by O. V. Godina, L. S. Maksimenko, Yu. V. Alekseenko, D. A. Kolominskaya

“…Examining the specifics of ecosystem marketing makes it possible to develop effective customer relationship management tools and a robust foundation for cultivating customer loyalty. …”
Get full text

Healthcare Personnel Opinion and their Implementation Obstacles Regarding the Standard Precautions in Hemodialysis Unit by Salwa ElBadry, Mervat A. Ghaleb, Nesreen A. M. Abou Zeid

“… Context: Hemodialysis HD patients, as well as the dialysis staff, are vulnerable to contracting health-care-associated infections (HAIs) due to frequent and prolonged exposure to many possible contaminants in the dialysis environment. …”
Get full text

Reliable protein–protein docking with AlphaFold, Rosetta, and replica exchange by Ameya Harmalkar, Sergey Lyskov, Jeffrey J Gray

Get full text

Development of ELISAs for diagnosis of acute typhoid fever in Nigerian children. by Jiin Felgner, Aarti Jain, Rie Nakajima, Li Liang, Algis Jasinskas, Eduardo Gotuzzo, Joseph M Vinetz, Fabio Miyajima, Munir Pirmohamed, Fatimah Hassan-Hanga, Dominic Umoru, Binta Wudil Jibir, Safiya Gambo, Kudirat Olateju, Philip L Felgner, Stephen Obaro, D Huw Davies

“…Improved serodiagnostic tests for typhoid fever (TF) are needed for surveillance, to facilitate patient management, curb antibiotic resistance, and inform public health programs. To address this need, IgA, IgM and IgG ELISAs using Salmonella enterica serovar Typhi (S. …”
Get full text

An innovative hematopoietic stem cell gene therapy approach benefits CLN1 disease in the mouse model by Marco Peviani, Sabyasachi Das, Janki Patel, Odella Jno‐Charles, Rajesh Kumar, Ana Zguro, Tyler D Mathews, Paolo Cabras, Rita Milazzo, Eleonora Cavalca, Valentina Poletti, Alessandra Biffi

Get full text

Insight into interplay between PANoptosis and autophagy: novel therapeutics in ischemic stroke by He-Yan Tian, Yun-Xing Lei, Jing-Tao Zhou, Long-Jun Liu, Tong Yang, Yue Zhou, Jin-Wen Ge, Jin-Wen Ge, Chen Xu, Zhi-Gang Mei

“…PANoptosis is a novelly defined mode of programmed cell death that involves the activation of multiple cellular death pathways, including pyroptosis, apoptosis, and necroptosis, triggering robust inflammatory reactions. …”
Get full text

Thalamic oscillatory dysrhythmia and disrupted functional connectivity in thalamocortical loops in perinatal stroke by Anton Rogachov, Helen L. Carlson, Amanda Robertson, Trish Domi, Adam Kirton, Nomazulu Dlamini

Get full text

Invited review: Management of genetic defects in dairy cattle populations by John B. Cole, Christine F. Baes, Sophie A.E. Eaglen, Thomas J. Lawlor, Christian Maltecca, M. Sofía Ortega, Paul M. VanRaden

Get full text

TrBot: A Turkish Deep Learning Chatbot Utilizing Seq2Seq Model by Bilal Babayigit, Habibelahi Rahmani, Mohammed Abubaker

“…The development of TrBot has significant implications, offering potential benefits in areas such as customer support, language learning, and other fields that require robust Turkish conversational capabilities. This study demonstrates that with adequate data and appropriate modeling techniques, it is possible to create effective conversational agents for complex languages like Turkish, paving the way for further advancements in this domain.…”
Get full text