Results of the ORION open comparative randomized trial: evaluation of efficacy of the Russian drugs Altevir and Phosphogliv in combined treatment of chronic hepatitis C by V. T. Ivashkin, M. V. Mayevskaya, P. O. Bogomolov, I. G. Nikitin, A. O. Buyeverov, A. V. Lapshin

“…Overall 80 out-patients over 18 years of age with the diagnosis of CHC confirmed by laboratory and instrumental methods have been included in original study. Patients in group A (n=40) prior to onset of AVT received phosphogliv intravenously (iv) 2,5 g 5 infusions per week for 4 wks, in the subsequent 4 wks it was applied iv on a background of AVT by Altevir® and ribavirin. …”
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Potential of albumin dialysis at terminal liver failure in patients with chronic liver diseases by O. E. Nikiforova, Ye. N. Bessonova, O. M. Lesnyak, O. A. Stroganova

“…Overall 65 patients with chronic terminal liver diseases of Child–Pugh B and C classes have been included in original study. The first (main group) included 25 patients, that received albumin dialysis in addition to traditional drug therapy. …”
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Application of ursodeoxycholic acid at non-alcoholic and alcohol-induced steatohepatitis by Ye. A. Fedos’ina, M. V. Mayevskaya

“…To cite the literature data, confirming efficacy of ursodeoxycholic acid (UDCA) at alcoholic and non-alcoholic steatohepatitis (NASH).Original positions. Prevalence of liver steatosis as pathomorphologic substrate of various liver diseases is quite high, however the special attention is given to patients with signs of inflammation and fibrosis, i.e. with confirmed alcohol-induced and non-alcoholic steatohepatitis. …”
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Genetic differentiation and historical dynamics of the endemic species Rheum pumilum on the Qinghai-Tibetan Plateau inferred from phylogeography implications by Shuliang Liu, Jianxin Gao, Bo Xiao, Wenjie Guo, Qiushi Yu, Ailan Wang, Weiwei Li

“…The involvement of Rh. kialense and Rh. sublanceolatum in the origin and gene introgression of Rh. pumilum is suggested, possibly as maternal ancestors of closely related haplotypes. …”
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Sierra Espuña (Librillos, 2023) by Miguel Ángel González Espinosa

“…In the lower part, we can see the Protected Landscape of the Barrancos de Gebas: the Algeciras reservoir (1995), which collects water from the ravine of the same name, between the Sierras de La Muela and del Cura. …”
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Coronil effectively inhibits the interaction of clinically relevant Omicron mutants of SARS-CoV-2 spike proteins with human ACE2 receptor by Acharya Balkrishna, Rishabh Dev, Sandeep Kumar, Anurag Varshney

“…Background: Accumulating evidence suggests that the receptor binding domain (RBD) of the SARS-CoV-2 Omicron variant has several times more binding affinity to the human angiotensin-converting enzyme 2 (ACE2) receptor compared to the RBD of the original Covid-19 strain. This increased binding affinity of the Omicron variant is responsible for its increased internalization and infectivity. …”
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Temporospatial Variation, Chemical Composition, and Source Resolution of PM2.5 in the Southeastern Taiwan Island by Chung-Shin Yuan, Jun-Hao Ceng, Po-Hsuan Yen, Kuan-Chen Chiang, Yu-Lun Tseng, Kwok-Wai Wong, Ming-Shiou Jeng

“…Trajectory simulation indicated that high PM2.5 concentrations were mostly originated from North and Central China, Japan islands, and Korea Peninsula. …”
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Levels, Chemical Compositions, and Sources of PM2.5 of Rural and Urban Area under the Impact of Wheat Harvest by Zhiyong Li, Ziyuan Yue, Dingyuan Yang, Lei Wang, Xin Wang, Zhenxin Li, Yutong Wang, Lan Chen, Songtao Guo, Jinsong Yao, Xiao Lou, Xiaolin Xu, Jinye Wei

“…Additionally, we found high geo-accumulation index (Igeo) values for crustal elements at both sampling sites, indicating that the dust emissions originated from the WH. Between DWH and AWH, the share of soil dust in the PM2.5 decreased from 21.3% to 7.98% and from 9.40% to 6.75% at ARS and UA, respectively. …”
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Assessment of in vitro skin permeation and accumulation of phenolic acids from honey and honey-based pharmaceutical formulations by Anna Nowak, Anna Muzykiewicz-Szymańska, Magdalena Perużyńska, Edyta Kucharska, Łukasz Kucharski, Karolina Jakubczyk, Paulina Niedźwiedzka-Rystwej, Justyna Stefanowicz-Hajduk, Marek Droździk, Juraj Majtan

“…This study aimed to identify and quantify phenolic acids in four Polish honey samples of different botanical origins (heather, buckwheat, linden and rapeseed) and to assess for the first time the permeation of the identified phenolic acids through the skin and their accumulation after the application of pure honey samples, as well as honey-based hydrogel and emulsion formulations. …”
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Prevalence of malocclusion and orthodontic treatment need in a sample of 12-15-year-old kurdish schoolchildren in Ranyia district by Zana Qadir Omer, Hashem Omer Karim

“…Background and objectives: In recent years, much attention has been focused on measuring the severity and prevalence of malocclusion and orthodontic treatment need worldwide,in particular, the aetiological importance of genetic factors has been reduced, considering that many malocclusions recognize a post-natal origin related to habits at early stages of life and trauma.This study aimed to determine the prevalence of malocclusion and to evaluate the need for orthodontic treatment in school going children in Ranyia district in Kurdistan region of Iraq. …”
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Comprehensive genomic and transcriptomic profiling of pulmonary nodules in synchronous multiple primary lung cancer by Xingsheng Liu, Kun Qian, Lei Su, Xiaoru Tian, Xin Zhao, Tengteng Wang, Li Han, Zhenzhen Li, Peilong Zhang, Ruotian Wang, Baodong Liu, Yuanbo Li, Xiaogang Tan, Yi Zhang

“…Methods We performed targeted DNA sequencing on tumor specimens and conducted bulk RNA transcriptome analysis on 53 multiple nodules originating from 26 lung cancer patients. The multiple nodules from the same patient was determined as major nodule and minor nodule. …”
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How Do Diabetes Models Measure Up? A Review of Diabetes Economic Models and ADA Guidelines by Lindsay Govan, Olivia Wu, Robert Lindsay, Andrew Briggs

“…Only unique models, and only the original papers were included in the review. If additional information was reported in subsequent or paired articles, then additional citations were included. …”
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Effects of Brackish Water with Different Sodium-Potassium Ratios on Soil Water-Salt Characteristics and Winter Wheat Growth by GAO Weiqiang, ZHANG Tibin, TONG Jiankang, LIU Zhenyuan, LIANG Qing, KUANG Yuxin, CHENG Yu, FENG Hao

“…[Methods] A pot experiment of winter wheat was carried out under the condition of rain-shielding. Deionized water was used as the control (CK). …”
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Generalising axion-like particle as the curvaton: sourcing primordial density perturbation and non-Gaussianities by Anish Ghoshal, Abhishek Naskar

“…Subsequently the ALP decays converting the isocurvature perturbations to adiabatic perturbations thereby acting as the origin of the primordial density perturbations. We identify the parameter space involving the axion decay constant $$f_{\phi }$$ f ϕ , scale of confinement $$\Lambda $$ Λ , ALP mass m and the masses of the fermions, $$m_u$$ m u and $$m_d$$ m d where it can satisfactorily behave as the curvaton and source the observed primordial density perturbation. …”
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Sub-seasonal Patterns of PM10 and Black Carbon in a Coastal City: A Case Study of Salé, Morocco by Anas Otmani, Abdeslam Lachhab, Abdelfettah Benchrif, Mounia Tahri, Mohamed Azougagh, Mohammed El Bouch, El Mahjoub Chakir

“…This observation, in conjunction with the identified disparities in BC levels between PM10 and PM2.5 fractions (BC2.5/BC10 ratio of 13 ± 4%), underscores the significance of accounting for particle size in appraising air quality. The primary origin of BC2.5 emissions was found to be traffic, making a substantial contribution to overall concentrations. …”
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The effect of bacterial overgrowth syndrome and bacterial translocation on the course of liver cirrhosis by M. S. Zharkova, M. V. Mayevskaya, V. T. Ivashkin

“…Overall 42 LC patients were included to original study (Child-Pugh class A – 15 patients, class B – 10, class C – 17). …”
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Long-term trends in the burden of multiple myeloma in China: a Joinpoint regression and age-period-cohort analysis based on GBD 2021 by Yanyu Zhang, Quanxin Su, Jiawen Yu, Xiuli Sun

“…PurposeMultiple myeloma (MM) is a hematologic malignancy originating from plasma cells with clinical manifestations such as hypercalcemia, cytopenias (most commonly anemia) and renal failure. …”
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Written monuments in old Prussian by Letas Palmaitis

“…Holzwescher from an older original, which may be dated to the beginning of the 14th century or even the end of the 13th century. …”
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Detection of Masses in Mammogram Images Based on the Enhanced RetinaNet Network With INbreast Dataset by Wang M, Liu R, Luttrell IV J, Zhang C, Xie J

“…Specifically, we introduced a novel modification to the network structure, where the feature map M5 is processed by the ReLU function prior to the original convolution kernel. This strategic adjustment was designed to prevent the loss of resolution for small mass features. …”
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Disorders of esophageal clearance in gastroesophageal reflux disease and option of their treatment by O. A. Storonova, A. S. Trukhmanov, N. L. Dzhahaya, V. T. Ivashkin

“…Overall 30 patients whose symptoms included heartburn (100%), burning chest pain (70%), belching (30%) were enrolled in original study. Of them 16 were women and 14 – men, mean age – 46,02 years (22 to 74 years). …”
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