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9981
Targeting Cancer Cell Fate: Apoptosis, Autophagy, and Gold Nanoparticles in Treatment Strategies
Published 2025-06-01“…Apoptosis serves as the principal mechanism of programmed cell death, while autophagy offers a dualistic role—preserving survival under transient stress or contributing to cell death under sustained insult. …”
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9982
Microbial Food Safety and Antimicrobial Resistance in Foods: A Dual Threat to Public Health
Published 2025-07-01“…We further discuss the evolution of surveillance systems, regulatory policies, and antimicrobial stewardship programs (ASPs) designed to mitigate resistance across the food chain. …”
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9983
Sexual and gender-related violence against girls in sub-Saharan Africa: a need for effective interventions
Published 2024-10-01“…SGRV generates fear, anxiety, and depression and leads to multiple adverse outcomes; its pervasive nature constitutes a significant public health crisis; the need for effective interventions is evident as currently applied programs have known limitations, and 1 in 3 women still suffer gender-based violence in their lifetime. …”
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9984
Critical Roles of Balanced T Helper 9 Cells and Regulatory T Cells in Allergic Airway Inflammation and Tumor Immunity
Published 2021-01-01“…When counteracted by different classes of pathogens, naïve CD4+T cells undergo programmed differentiation into distinct types of Th cells. …”
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9985
The role of transglutaminase 2 in regulation of the balance between autophagy and apoptosis in tumor cells
Published 2023-12-01“…In normal tissue, cellular homeostasis is largely driven by two catabolic pathways: apoptosis and autophagy. Apoptosis, or programmed cell death, is regulated by pro-apoptotic factors, and promotes the removal of problematic cells. …”
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9986
Assessment of genotoxicity biomarkers in neotropical fish species from streams of the Ivinhema River basin located in sugarcane cultivation areas
Published 2024-11-01“…These results contribute to the generation of data and information that can be used for public hearing requests that aim to discuss and review many aspects of legislation regarding agricultural activities around streams, as well as the need for restoration and management programs in these areas in order to conserve biodiversity.…”
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9987
The Association Among Bipolar Disorder, Mitochondrial Dysfunction, and Reactive Oxygen Species
Published 2025-03-01“…Mitochondria play crucial roles in maintaining calcium balance, regulating apoptosis (programmed cell death), supporting cellular signaling, influencing cell metabolism, and synthesizing reactive oxygen species (ROS). …”
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9988
Identifying key factors influencing maize stalk lodging resistance through wind tunnel simulations with machine learning algorithms
Published 2025-06-01“…Through extensive field experiments and literature review, we identified and measured 74 phenotypic traits encompassing plant morphology, biomass, and anatomical characteristics in maize plants. …”
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9989
LAG-3: from molecular functions to clinical applications
Published 2020-10-01“…Inhibitory coreceptors, including programmed cell death 1 (PD-1) and cytotoxic T lymphocyte antigen 4 (CTLA-4), serve as critical checkpoints in restricting immune responses against self-tissues and tumor cells. …”
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9990
Implementation of intentionally structured psychosocial through folk games and traditional sports in elementary school students
Published 2024-11-01“… This study aimed to examine the impact of intentionally structured psychosocial programs through folk games and traditional sports on elementary school students. …”
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9991
T lymphocyte-targeted immune checkpoint modulation in glioma
Published 2020-05-01“…Although initial clinical results in patients with glioblastoma (GBM) were disappointing, recently published results have demonstrated a potential survival benefit in patients with recurrent GBM treated with neoadjuvant programmed cell death protein 1 blockade. While these findings necessitate verification in subsequent studies, they support the possibility of achieving clinical meaningful immune responses in malignant primary brain tumors including GBM, a disease in dire need of additional therapeutic options. …”
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9992
Mammographic Screening as a Tool for Cardiovascular Risk Assessing. Part 1. Breast Arterial Calcification: Pathomorphology, Prevalence and Risk Factors
Published 2019-05-01“…The prevalence of BAC (data from cancer screening programs) is about 12.7%, and it increases with age to 50% in 80-year-old women. …”
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9993
Role of mass spectrometry-based serum proteomics signatures in predicting clinical outcomes and toxicity in patients with cancer treated with immunotherapy
Published 2022-03-01“…In addition, the predictive ability of current biomarkers such as programmed death-ligand 1 (PD-L1) remains unreliable and establishing better potential candidate markers is of great importance in selecting patients who would benefit from immunotherapy. …”
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9994
The Effect of Diaphragmatic Breathing as a Complementary Therapeutic Strategy in Stress of Children and Teenagers 6–18 Years Old
Published 2025-01-01“…Objective: The goal of the review is to evaluate the effectiveness of DB as complementary therapy in the stress of the pediatric population (6–18 years old). …”
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9995
Tourism Management System in Mongolia: the Case of Gorkhi-Terelj National Park
Published 2022-06-01“…Training opportunities in Mongolian tourism sector are limited also by lack of professional training institutions with training programs prepared on the basis of existing training needs. …”
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9996
Humanitarian Cooperation in Sport on Space of the CIS as an Integration Factor
Published 2018-04-01“…Many programs of regional cooperation of Russia and the CIS countries in the field of physical culture and sport have found reflection in work. …”
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9997
Electronic Medical Record Inaccuracies: Multicenter Analysis of Challenges with Modified Lung Cancer Screening Criteria
Published 2020-01-01“…We performed a multicenter review of all individuals referred to three LCS programs from 2012 to 2015. …”
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9998
Guided Education and the Fundamentals of Arthroscopy Surgery Training (FAST) Workstation Improve Surgical Resident Knot-tying Skills
Published 2025-06-01“…Information from this study can be used by residency programs to ensure the proficiency of their trainees.…”
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9999
Farmers knowledge, attitude, and practices towards compliance with beef safety standard practices in Uganda
Published 2025-07-01“…The study recommends that the government and development partners undertake a review of the Meat and Disease Act to implement stringent penalties for non-compliance and to enhance the enforcement of beef safety regulations. …”
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10000
Genetic drivers of tumor microenvironment and immunotherapy resistance in non-small cell lung cancer: the role of KEAP1, SMARCA4, and PTEN mutations
Published 2025-08-01“…The presence of these mutations is associated with poor outcomes, independent of tumor mutational burden or programmed death-ligand 1 expression, and their co-occurrence, particularly with KRAS and STK11, further compounds resistance. …”
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