Suggested Topics within your search.
Suggested Topics within your search.
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9721
CHD1L in cancer and beyond: structure, oncogenic functions, and therapeutic potential
Published 2025-05-01“…Abstract Chromodomain Helicase DNA-binding protein 1-Like (CHD1L) is a chromatin remodeling enzyme increasingly recognized as an oncogenic factor promoting tumor progression and metastatic potential by orchestrating transcriptional programs that drive epithelial-mesenchymal transition (EMT), cytoskeletal remodeling, and metastatic dissemination. …”
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9722
Drought in Equity Initial Public Offers in Kenya: A Demand Perspective
Published 2025-03-01“…Security market promoters and regulators are called upon to review key concerns of investors specifically IPO market efficiency and quality of listing firms among others as well as devise programs to train and educate retail investors on assessing attractiveness of issue firm and investment strategies to adopt in IPO market. …”
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9723
Semantic Self-Regulation in Context of Teachers’ Experiences of Professional Identity Crisis
Published 2018-01-01“…The practical significance of the results is determined by the fact that they constitute the information basis for the development of individualized programs of psychological support of teachers in a situation of professional identity crisis.…”
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9724
The Impact of Heat Stress on Canola (<i>Brassica napus</i> L.) Yield, Oil, and Fatty Acid Profile
Published 2025-06-01“…The purpose of this literature review was to assess the impact of heat stress on canola while briefly evaluating other abiotic stresses, and to address the following research questions: (1) What is the impact of heat stress on canola yield?…”
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9725
The community health worker model for cardiovascular kidney metabolic syndrome: A new paradigm for high value care
Published 2025-03-01“…Access and adherence to prevention and therapeutic lifestyle change programs remain largely aspirational for many low resource and minority communities. …”
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9726
ACTIVITIES OF LEADING AMERICAN AND WESTERN EUROPEAN VOLUNTEER ORGANIZATIONS IN UKRAINE (2014–2024)
Published 2024-06-01“…However, until 2014, these organizations implemented programs related to environmental protection, entrepreneurship development, English language learning, etc. …”
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9727
The Three Paralogous MicroRNA Clusters in Development and Disease, miR-17-92, miR-106a-363, and miR-106b-25
Published 2016-01-01“…There is a fine balance between deregulation of normal developmental programs and tumor genesis. An increasing body of evidence suggests that altered expression of miRNAs is entailed in the pathogenesis of human cancers. …”
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9728
Use of phase angle as an indicator of overtraining in sport and physical training
Published 2024-11-01“…Its use in sports is rapidly expanding due to the valuable insights it offers, helping to better structure athletes’ diets and training programs, thereby optimizing their performance. In the context of sport, however, there is a consensus regarding the importance of proper interpretation of BIA-derived data, which cannot be limited to mere estimation of body composition. …”
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9729
On the presence of sustainable growth trends in the research sector in the RF territories
Published 2025-01-01“…The paper identifies the stability of the results of the functioning of the research sector in the territories of the federal districts of the Russian Federation.Materials and methods The paper is based on the study of the theoretical foundations for ensuring the effective work of the scientific sector, the review of advanced technological programs in Russia and the world, the justification of a system of quantitative criteria for an objective assessment of the functioning of fundamental science.Results and discussion. …”
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9730
Metaphorical Perceptions of the Concept of Sustainability Among Students of the Faculty of Health Sciences: “It Is Like a Domino Piece”
Published 2024-12-01“…In order for students to understand sustainability in depth, it may be recommended to review course programs and plan research.…”
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9731
The immune exhaustion paradox: activated functionality during chronic bacterial infections
Published 2024-12-01“… Co-inhibitory molecules, such as cytotoxic T-lymphocyte-associated protein 4 (CTLA-4) and programmed cell death protein 1 (PD-1), known as immune checkpoints, regulate the activity of T and myeloid cells during chronic viral infections and are well-established for their roles in cancer therapy. …”
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9732
Targeting CX3CR1 Signaling Dynamics: A Critical Determinant in the Temporal Regulation of Post-Stroke Neurorepair
Published 2025-07-01“…The CX3CR1/CX3CL1 signaling axis, highly expressed in microglia, acts as a key regulator. This review examines the spatiotemporal dynamics of the axis across the stroke process and its involvement in neural repair. …”
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9733
Strategic planning of zone one district 22 of Tehran based on the indicators of an elderly-friendly city
Published 2022-02-01“…According to the studies conducted, some of the needs of the elderly, including (medical centers, recreational programs, safety and security of the elderly) have not been taken into account in zone one of district 22.…”
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9734
Inter-Territorial Calculations for Identifying Imbalances and Problems in Health Insurance
Published 2025-06-01“…Regional compulsory health insurance funds provide citizens with free medical care as part of state healthcare programs. The article introduces an in-depth analysis of the revenue and expenditure budget structure of regional compulsory health insurance funds with a focus on the inter-territorial calculations. …”
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9735
La educación contable de calidad y sus retos para abordar los desafíos de un entorno cambiante
Published 2022-07-01“…From the above, there is a need to analyze how those who offer Public Accounting programs, and practicing professionals, are addressing the commitment to guarantee professional competence through quality education. …”
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9736
Regulatory landscape for pediatric hematology–oncology nursing in Brazil: document analysis of policies and regulations
Published 2025-06-01“…Qualitative analysis used both inductive and deductive approaches to identify themes. Results. The review included 25 documents: 11 regulatory, 11 governmental (including one national and two state plans), and three educational documents. …”
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9737
Central and territorial governmental institutions involved in health promotion for older people in European Union countries
Published 2022-03-01“…In the majority of analysed countries, the central government and municipalities are the main stakeholders responsible for providing funding for these programs. The operational level for the implementation of majority HP4OP is the local level. …”
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9738
Targeting of the SWI/SNF chromatin remodeling complex in cancer therapy
Published 2023-04-01“…Genes encoding protein subunits of SWI/ SNF remodeling complexes often mutate and/or change their expression in human tumors, affecting the expression programs of many genes during carcinogenesis, which is associated with the occurrence and progression of cancer. …”
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9739
Sorghum aphid/greenbug: current research and control strategies to accelerate the breeding of aphid-resistant sorghum
Published 2025-06-01“…However, the resistance genes of aphids and their mechanisms are still unclear, which poses a major challenge to breeding programs. This review synthesizes recent advances in understanding the interactions between sorghum and these two major aphid species, exploring topics such as aphid classification, quantitative trait locus (QTL) mapping of resistance genes, and the molecular mechanisms of sorghum-aphid interactions. …”
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9740
Dietary Interventions and Physical Activity as Crucial Factors in the Prevention and Treatment of Metabolic Dysfunction-Associated Steatotic Liver Disease
Published 2025-01-01“…Due to the ever-increasing number of patients, the long-term asymptomatic course of the disease, serious complications, and lack of preventive programs, as well as insufficient awareness of the disease among patients and doctors themselves, MASLD is a growing interdisciplinary problem and a real challenge for modern medicine. …”
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