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  1. 9561

    Effects of breeding activity on durum wheat traits breed in Italy during the 20th century by Luigi Cattivelli, Natale Di Fonzo, Anna Maria Mastrangelo, Loredana Matteu, Pasquale De Vita

    Published 2007-12-01
    “…Italy is the first world producer of pasta from durum wheat (Triticum durum Desf.) and an intense breeding activity has been conducted over the last century to support the long tradition of pasta making. This manuscript reviews the results achieved through the Italian breeding programs over last century. …”
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  2. 9562

    Survey of Distributed Computing Frameworks for Supporting Big Data Analysis by Xudong Sun, Yulin He, Dingming Wu, Joshua Zhexue Huang

    Published 2023-06-01
    “…In this paper, we review MapReduce-type distributed computing frameworks that are currently used in handling big data and discuss their problems when conducting big data analysis. …”
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  3. 9563

    Genetic and molecular insights in oral squamous cell carcinoma therapy - Advancing the horizon by Prathiksha Srikanthan, Suresh Malakondaiah, Iadalin Ryntathiang, Mukesh Kumar Dharmalingam Jothinathan

    Published 2024-09-01
    “…This editorial aims to review the current genetic and molecular data of OSCC treatment with an emphasis on the Programmed cell death protein 1 (PD-1)/ligand PD-L1 pathway and novel biomarkers. …”
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  4. 9564

    Exploring the Revolutionary Impact of YAP Pathways on Physical and Rehabilitation Medicine by Carmelo Pirri

    Published 2025-01-01
    “…YAP is known for its capacity to perceive and translate mechanical signals into specific transcriptional programs within cells. This insight has opened up new perspectives on how physical and rehabilitation medicine may exert its beneficial effects. …”
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  5. 9565

    Emerging Ferroptosis Involvement in Amyotrophic Lateral Sclerosis Pathogenesis: Neuroprotective Activity of Polyphenols by Annamaria Russo, Stefano Putaggio, Ester Tellone, Antonella Calderaro, Santa Cirmi, Giuseppina Laganà, Silvana Ficarra, Davide Barreca, Giuseppe Tancredi Patanè

    Published 2025-03-01
    “…Indeed, many pathways implicated in the disease are hallmarks of ferroptosis, a recently discovered type of iron-dependent programmed cell death characterized by increased reactive oxygen species (ROS) and lipid peroxidation. …”
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  6. 9566

    NLRP3 inflammasome and pyroptosis: implications in inflammation and multisystem disorders by Xiaodi Li, Zhiyuan Zhang, Yang Han, Mianzhi Zhang

    Published 2025-08-01
    “…Pyroptosis is a form of programmed cell death that plays a crucial role in immune responses and inflammatory processes. …”
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  7. 9567

    Two cases of adult-onset de novo immunoglobulin A vasculitis with nephritis: Post-Covishield (ChAdOx1 nCoV-19; Oxford–Astra Zeneca) vaccination by Vijoy Kumar Jha, Ramanjit Singh Akal, Debasish Mahapatra, S Harikrishnan, Gurpreet Kaur Walia

    Published 2022-01-01
    “…With the ongoing worldwide COVID-19 vaccination programs, new-onset glomerular disease and relapse of the preexisting glomerular disease have been reported after COVID-19 vaccines administration. …”
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    Article
  8. 9568

    Predictive biomarkers for targeted therapy in daily anatomic pathology for ovarian tumors by Niti Sureka, Sufian Zaheer

    Published 2025-06-01
    “…Emerging biomarkers like programmed death-ligand 1 (PD-L1) expression and angiogenesis markers such as VEGF further enhance therapeutic strategies, paving the way for combination treatments in refractory and relapsed cases. …”
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  9. 9569

    Recent advances on gene-related DNA methylation in cancer diagnosis, prognosis, and treatment: a clinical perspective by Alessandro Lavoro, Daria Ricci, Giuseppe Gattuso, Federica Longo, Graziana Spoto, Anastasia Cristina Venera Vitale, Maria Chiara Giuliana, Luca Falzone, Massimo Libra, Saverio Candido

    Published 2025-05-01
    “…Abstract Recent advances in screening programs and the development of innovative therapeutic strategies have significantly improved the clinical outcomes of cancer patients. …”
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  10. 9570

    The generation of novel epialleles in plants: the prospective behind re-shaping the epigenome by Alessio Baldini, Filippo Battaglia, Giorgio Perrella

    Published 2025-03-01
    “…The promising results obtained by altering the expression state of targets involved in flowering time and abiotic stress resistance are crucial not only for elucidating the molecular interactions that underly chromatin dynamics, but also for future applications in breeding programs as an alternative route to genetic manipulation towards the achievement of higher quality crops particularly in terms of nutritional properties, yield and tolerance.…”
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  11. 9571

    Cheong Wa Dae: The Sustainability and Place-Making of a Cultural Landmark, Reflecting Its Role in History and Architecture by Ja-young Eunice Kim, Yong-hwan Shim

    Published 2025-01-01
    “…Programs were evaluated through the Sustainability Impact Assessment tool to measure their ecological, cultural, and socio-economic impacts. …”
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  12. 9572

    Unraveling the immunomodulatory role of TIM-3 in head and neck squamous cell carcinoma: implications for targeted therapy by Shuang Xu, Yang Luo, Yuzhu He, Yuxiang Chen, Fengfeng Qin, Wenjian Hu

    Published 2025-05-01
    “…With increased research in immunotherapy, antibodies against various immune checkpoints like programmed death receptor 1 (PD-1) and cytotoxic T-lymphocyte antigen 4 (CTLA-4) have been shown to be effective against a wide range of tumors. …”
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  13. 9573

    FACTORS THAT INFLUENCE THE DISTRIBUTION OF WILD TURKEYS IN MICHIGAN by Steven B. Chadwick

    Published 2005-01-01
    “…These limiting factors may be overcome in some portions of the state through habitat management programs that mitigate winter loss.…”
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  14. 9574

    Expert Consensus on Diagnosis and Molecular Testing Strategies for Non-Small-Cell Lung Cancer in India by Bivas Biswas, Trupti Pai, Nirmal Raut, Vidya Manur Narasimhamurthy, Bijal Kulkarni, Ashish Singh, Sunil Pasricha, Jayesh Deshmukh, Sewanti Limaye

    “…This review aims to establish expert consensus on biomarker testing for non-small-cell lung cancer (NSCLC) in India, evaluating diagnostic practices, adherence to international guidelines, and test utility and comparing clinically validated assays with laboratory-developed tests. …”
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  15. 9575

    Enhancing Emergency Cognitive Ability in College Students Under Emergencies: A Study of Influencing Factors and Hierarchical Relationships by Lei Chen, Hongxia Li

    Published 2024-11-01
    “…To fill the gap in understanding these relationships, we used grounded theory to identify 12 influencing factors through a literature review, case analysis, and interviews. The interpretive structural modeling (ISM) method categorized these factors into three levels: direct, key, and root factors. …”
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  16. 9576

    The Progress and Challenges of Implementing HLA Molecular Matching in Clinical Practice by Suzanne Bezstarosti, Sebastiaan Heidt

    Published 2025-08-01
    “…While many studies have shown the association between molecular mismatches and de novo donor-specific antibody formation, rejection and graft loss, evidence for prospective molecular matching in allocation is currently lacking, and the actual practical implementation and feasibility of molecular matching remains unclear. In this review the various potential applications of molecular matching in transplantation are discussed, including 1) organ allocation in deceased donor programs, 2) living donor selection, 3) increasing the transplantability of highly sensitized patients and 4) risk stratification to facilitate personalized immunosuppressive management, along with the challenges and gaps in current knowledge regarding these approaches. …”
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  17. 9577

    The role of stem cell-derived exosomes in regulating pyroptosis for disease therapy by Yilin Guo, Qiyin Liu, Jingjun Yang, Yan Gao, Ying Liu

    Published 2025-07-01
    “…Abstract Pyroptosis, a form of programmed cell death, is widely involved in the occurrence and development of various diseases. …”
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  18. 9578

    Information and communication technologies (icts) in the consolidation of the mango economy in the district of Ferkessédougou by Bi Marie Richard Nicétas ZOUHOULA, Ismaïla DOSSO, Céba Timothée KELY

    Published 2023-12-01
    “…As for data collection, it was based on a mixed technique which associated literature review with the use of reports on national agricultural programs for secondary information, direct observation in the field and individual interviews, for primary information. …”
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  19. 9579

    Choline in immunity: a key regulator of immune cell activation and function by Catarina Maia, Chin Wai Fung, Elsa Sanchez-Lopez

    Published 2025-08-01
    “…Immune cells, which must rapidly activate transcriptional, proteomic, and metabolic programs to fulfill their functional roles, depend on nutrient supply to generate the building blocks needed for the production of immune effectors. …”
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  20. 9580

    Asthma and obesity in children: what do we know? by G. A. Novik, E. G. Khaleva, S. G. Makarova, M. V. Zhdanova

    Published 2019-10-01
    “…The relationship of asthma and obesity can have both a genetic basis and can occur under the influence of a complex of pathogenic factors, and they can be especially important at the “early programming” stage. Obesity increases the risk of asthma development, and in patients with existing asthma due to a number of mechanisms it increases the severity or makes it difficult to achieve control of asthma. …”
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