Genetic gradual reduction of OGT activity unveils the essential role of O-GlcNAc in the mouse embryo. by Sara Formichetti, Agnieszka Sadowska, Michela Ascolani, Julia Hansen, Kerstin Ganter, Christophe Lancrin, Neil Humphreys, Mathieu Boulard

“…The reversible glycosylation of nuclear and cytoplasmic proteins (O-GlcNAcylation) is catalyzed by a single enzyme, namely O-GlcNAc transferase (OGT). …”
Get full text

Electrochemical Reduction of CO2 in a Zero‐Gap Electrolyzer Cell on a Metal Molecular Electrocatalyst by Simphiwe L. Ndlangamandla, Shankara G. Radhakrishnan

“…Electrochemical reduction of CO2 (ECR) on transition metal‐containing porphyrin systems often leads to carbon monoxide. …”
Get full text

Investigating the Associations Between Hmga2 Overexpression, R-Loop Reduction, and Bone Loss in Aging Mice by Yangyang Cao, Yantong Wang, Dengsheng Xia

Get full text

Revisiting Abnormalities of Ventricular Depolarization: Redefining Phenotypes and Associated Outcomes Using Tree‐Based Dimensionality Reduction by Mehak Gurnani, Konstantinos Patlatzoglou, Joseph Barker, Derek Bivona, Libor Pastika, Ewa Sieliwonczyk, Boroumand Zeidaabadi, Paolo Inglese, Lara Curran, Ahran D. Arnold, Declan O'Regan, Zachary Whinnett, Kenneth C. Bilchick, Nicholas S. Peters, Daniel B. Kramer, Jonathan W. Waks, Arunashis Sau, Fu Siong Ng

Get full text

Single-Cell RNA Transcriptomics and Multi-omics Analyses Reveal the Clinical Effects of Acupuncture on Methadone Reduction by Yiming Chen, Baochao Fan, Jingchun Zeng, Yutian Zou, Chenyang Tao, Chen Chen, Peiming Zhang, Jian Liang, Fangfang Qi, Hailin Tang, Liming Lu

“…After 8 weeks of intervention, 84% of patients in the acupuncture group achieved ≥20% reduction in methadone dosage, compared to 39% in the sham-acupuncture group (P < 0.01). …”
Get full text

Prediction of heterogeneous nucleation condensation effect on the surface of respiratory coal dust and test of dust reduction test by Hanyi LIN, Liang YUAN, Bingyou JIANG, Yuqian ZHANG, Yifan WANG, Haoyu WANG

Get full text

0.003°/h bias instability of honeycomb disk resonator gyroscope achieved by mode reversal combined mode deflection control method by Liangqian Chen, Qingsong Li, Tongqiao Miao, Peng Wang, Xuhui Zhang, Yang Zhang, Xuezhong Wu, Dingbang Xiao

“…Experimental results demonstrate that compared with the traditional force-to-rebalance mode, the new method achieves a 595 times reduction in bias variation during −40 °C to +60 °C temperature cycles and a 6.3 times reduction in bias instability at room temperature. …”
Get full text

Evaluation of the Effect of Reverse Curve of Spee in Nickel Titanium (NiTi) Wire with and Without Torque on Lower Incisors: A Clinical Study by Yash K. Shekatkar, MV Ashith, Sunil Muddiah, Rainee Solanki, Neelutpal Bora, K. PT Haneesh, Ranjan Bhat

“…There was a significant reduction in proclination of the incisors using 200 pretorqued reverse curve NiTi wire when compared with the conventional reverse curve NiTi.…”
Get full text

Fouling of Reverse Osmosis (RO) and Nanofiltration (NF) Membranes by Low Molecular Weight Organic Compounds (LMWOCs), Part 2: Countermeasures and Applications by Yasushi Maeda

Get full text

Carbon ion stimulation therapy reverses iron deposits and microglia driven neuroinflammation and induces cognitive improvement in an Alzheimer’s disease mouse model by Won-Seok Lee, Toshiaki Kokubo, Younshick Choi, Tsuyoshi Hamano, Alexander Zaboronok, Takaaki Ishikawa, Oh-Dae Kwon, EunHo Kim, Jong-Ki Kim

Get full text

A Case of Closed Pilon Fracture Resulting in Soft-Tissue Necrosis and Treated with Reverse Sural Artery Flap and Circular External Fixation by Ryu Igaki, Tomohiro Yasuda, Yuki Samejima, Yuko Irie, Yuto Murakami, Taisuke Yoneya, Shinsuke Takagi, Keikichi Kawasaki, Koji Kanzaki

“…Tibial pilon fractures are difficult to treat due to articular comminution and soft-tissue injuries caused by high-energy trauma. Open reduction and internal fixation is a commonly used method of treatment. …”
Get full text

Bronchoscopic lung lavage and exogenous surfactant successfully reverse respiratory failure after severe chlorine exposure: A pediatric case report by Paola Papoff, Benedetto D'Agostino, Roberto Cicchetti, Antonella Bitti, Valentina Pennetta, Elena Caresta

Get full text

Reversing Pathology in an Aggravated Fabry Mouse Model Using Low-Dose Engineered Human Alpha-Galactosidase A AAV Gene Therapy by Wanida Ruangsiriluk, Mugdha Deshpande, Natalia Boukharov, Girija Rajarshi, Shreya Mukherji, Shipeng Yuan, Jennifer Wiseman, Nancy Chen, Eric Park, Hyelim Cho, Rizwana Islam

“…AAV gene therapy with Eng-C demonstrated significantly greater substrate reduction in the severe Fabry G3Stg/<i>Gla</i>KO mouse model across all affected tissues. …”
Get full text

Estrogen replacement therapy reverses spatial memory loss and pyramidal cell neurodegeneration in the prefrontal cortex of lead-exposed ovariectomized Wistar rats by Abiodun Shukrat Lasisi-Sholola, Sodiq Opeyemi Hammed, Richard Adedamola Ajike, Roland Eghoghosoa Akhigbe, Oladele Ayobami Afolabi

Get full text

Sex-Specific Patterns and Predictors of Reverse Left Ventricular Remodeling and Outcomes in STEMI Patients with LVEF ≤ 50% After Successful Primary Angioplasty by Bogdan-Flaviu Buz, Sergiu-Florin Arnautu, Mirela-Cleopatra Tomescu, Minodora Andor, Simina Crisan, Dan Gaita, Cristina Vacarescu, Constantin-Tudor Luca, Cristian Mornos, Dragos Cozma, Diana-Aurora Arnăutu

“…<b>Methods</b>: We enrolled 253 STEMI patients (91 women, 28%) and assessed echocardiographic parameters at baseline and six months. LV reverse remodeling was defined as a ≥15% reduction in LV end-diastolic volume (LVEDV). …”
Get full text

Microglial repopulation reverses radiation-induced cognitive dysfunction by restoring medial prefrontal cortex activity and modulating leukotriene-C4 synthesis by Yubo Hu, Zhe Li, Yafeng Zhu, Mengdan Xing, Xiaoru Xie, Panwu Zhao, Xin Cheng, Chuan Xiao, Yuting Xia, Jingru Wu, Yuan Luo, Ho Ko, Yamei Tang, Xiaojing Ye, Wei-Jye Lin

“…Radiaiton exposure also causes a significant reduction in microglial density within the mPFC, accompanied by morphological and transcriptional alterations in the remaining microglia. …”
Get full text

Reversed Effects of Intermittent Theta Burst Stimulation following Motor Training That Vary as a Function of Training-Induced Changes in Corticospinal Excitability by Tino Stöckel, Jeffery J. Summers, Mark R. Hinder

“…That means the expected LTP-like effects of iTBS are reversed following motor learning.…”
Get full text

Management of Risk Factors in the Rental Car Market by Aldona Jarašūnienė, Nijolė Batarlienė, Benediktas Šidlauskis

“…The purpose of this article is to examine the risk management of car rental and evaluate the impact of a 5–10-year-old car rental model with reverse logistics on risk reduction and business efficiency. …”
Get full text

Use of sacubitril/valsartan in non‐compaction cardiomyopathy: a case report by Marcely Gimenes Bonatto, Rodrigo Albanez, Vera Maria Cury Salemi, Lídia Zytynski Moura

Get full text

Silver carp muscle hydrolysate ameliorated atherosclerosis and liver injury in apoE-/- mice: the modulator effects on enterohepatic cholesterol metabolism by Kai Wang, Zixin Fu, Yuqing Tan, Hui Hong, Jianping Wu, Yongkang Luo

“…The mechanism analysis showed SCH down-regulated the expression of genes involved in lipoproteins production while up-regulated the expression of genes related to reverse cholesterol transport (RCT) in liver. Meanwhile, SCH remarkably promoted transintestinal cholesterol excretion (TICE) process in intestine, partly contributing to the reduction of blood lipids. …”
Get full text