Assessing clenbuterol’s modulation of metabolic and inflammatory pathways in Nile tilapia (Oreochromas niloticous) fed high fat diet by Aya G. Rashwan, Doaa H. Assar, Abdallah S. Salah, Muyassar H. Abualreesh, Shimaa M. R. Salem, Norah Althobaiti, Zizy I. Elbialy

“…Nevertheless, clenbuterol supplementation significantly reversed the aforementioned findings induced by HFD. …”
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Effects of long-term pioglitazone treatment on peripheral and central markers of aging. by Eric M Blalock, Jeremiah T Phelps, Tristano Pancani, James L Searcy, Katie L Anderson, John C Gant, Jelena Popovic, Margarita G Avdiushko, Don A Cohen, Kuey-Chu Chen, Nada M Porter, Olivier Thibault

“…Starting at 3 months or 17 months of age, male rats were treated for 4-5 months with either a control or a PIO-containing diet (final dose approximately 2.3 mg/kg body weight/day). A significant reduction in the Ca(2+)-dependent afterhyperpolarization was seen in the aged animals, with no significant change in long-term potentiation maintenance or learning and memory performance. …”
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Intravitreal Faricimab for Previously Treated Neovascular Age-Related Macular Degeneration by Hang A, Ngo T, Virk JS, Moussa K, Moshiri A, Emami-Naeini P, Park SS

“…The benefit of faricimab on CST reduction may be diminished in eyes previously treated with multiple different types of anti-VEGF therapy.Keywords: anti-VEGF therapy, intravitreal therapy, real-world experience, central subfield thickness, optical coherence tomography…”
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Exercise enhances cardiomyocyte mitochondrial homeostasis to alleviate left ventricular dysfunction in pressure overload induced remodelling by Zhichao Ma, Yanling Cen, Weiwei Xun, Caiying Mou, Junwen Yu, Yarui Hu, Chen Liu, Jun Sun, Rui Bi, Yanli Qiu, Mingchao Ding, Li Jin

“…Overexpression of ndufb10 reversed pathological hypertrophy, mitochondrial autophagy, mitochondrial dysfunction, and cardiomyocyte apoptosis in vitro. …”
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Myricetin protects against doxorubicin-induced acute kidney injury in rats by mitigating oxidative damage and apoptotic response by Muhammed Talha Karadogan, Betul Cicek, Kagan Tolga Cinisli, Ali Sefa Mendil, Mustafa Ozkaraca, Furkan Yilmaz, Halis Suleyman

“…Furthermore, MYC demonstrated antioxidant properties by reversing the increase in MDA, TOS, and MPO levels and the decrease in GSH, GPx, and TAS levels caused by DOX (p < 0.05). …”
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Exploring the Characteristics of Atoxigenic <i>Aspergillus flavus</i> Isolates and Their Biocontrol Impact on Soil Fungal Communities by Yanyan Zhang, Wanning Wang, Chenggui Piao, Wenjin Li, Peter J. Cotty, Shihua Shan, Usman Rasheed, Quirico Migheli, Qing Kong

“…The results showed a reduction in the population density of harmful fungi, such as <i>Fusarium</i> spp. (66.18%) and <i>Plectosphaerella</i> spp. (79.90%), but an increase in the density of <i>Nothopassalora personata</i>. …”
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Iodine-131 induces ferroptosis and synergizes with sulfasalazine in differentiated thyroid cancer cells via suppressing SLC7A11 by Li Ling, Jinhe Zhang, Xiao Zhang, Peiqi Wang, Mingjun Ma, Bingling Yin

“…Ferrostatin-1 (Fer-1) reversed the cell viability and colony formation ability inhibited by 131I. 131I led to an elevation in the levels of malondialdehyde (MDA), reactive oxygen species (ROS), and lipid peroxidation. …”
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Implementation of a goal-directed Care Bundle for intracerebral hemorrhage: Results of embedded process evaluation in the INTERACT3 trial. by Menglu Ouyang, Anila Anjum, Francisca Gonzalez Mc Cawley, Mohammad Wasay, Lu Ma, Xin Hu, Xiaoying Chen, Alejandra Malavera, Xi Li, Paula Muñoz Venturelli, H Asita de Silva, Nguyen Huy Thang, Kolawole W Wahab, Jeyaraj D Pandian, Octavio M Pontes-Neto, Carlos Abanto, Venessa Cano-Nigenda, Antonio Arauz, Chao You, Stephen Jan, Lili Song, Craig S Anderson, Hueiming Liu, INTERACT3 Investigators

“…The third, stepped-wedge, cluster-randomized, Intensive Care Bundle with Blood Pressure Reduction in Acute Cerebral Hemorrhage Trial (INTERACT3), has shown that a goal-directed multi-faceted Care Bundle incorporating protocols for the management of physiological variables was safe and effective for improving functional recovery in a broad range of patients with acute intracerebral hemorrhage (ICH). …”
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RETRACTED: Evaluation of post-COVID mortality risk in cases classified as severe acute respiratory syndrome in Brazil: a longitudinal study for medium and long term by Nádia Cristina Pinheiro Rodrigues, Mônica Kramer de Noronha Andrade

“…After one year, the effect was reversed, showing an increased risk of death for those vaccinated. …”
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MicroRNA-Based Delivery Systems for Chronic Neuropathic Pain Treatment in Dorsal Root Ganglion by Stefan Jackson, Maria Rosa Gigliobianco, Cristina Casadidio, Piera Di Martino, Roberta Censi

“…However, the direct delivery of these nucleotides has been challenging due to limitations such as rapid clearance, degradation, and reduction in half-life. Therefore, safe and efficient carrier vehicles are fundamental for microRNA delivery. …”
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Investigation of SARS-CoV-2 infection in dogs and cats of humans diagnosed with COVID-19 in Rio de Janeiro, Brazil. by Guilherme Amaral Calvet, Sandro Antonio Pereira, Maria Ogrzewalska, Alex Pauvolid-Corrêa, Paola Cristina Resende, Wagner de Souza Tassinari, Anielle de Pina Costa, Lucas Oliveira Keidel, Alice Sampaio Barreto da Rocha, Michele Fernanda Borges da Silva, Shanna Araujo Dos Santos, Ana Beatriz Machado Lima, Isabella Campos Vargas de Moraes, Artur Augusto Velho Mendes Junior, Thiago das Chagas Souza, Ezequias Batista Martins, Renato Orsini Ornellas, Maria Lopes Corrêa, Isabela Maria da Silva Antonio, Lusiele Guaraldo, Fernando do Couto Motta, Patrícia Brasil, Marilda Mendonça Siqueira, Isabella Dib Ferreira Gremião, Rodrigo Caldas Menezes

“…Additionally, blood samples were collected for laboratory analysis, and plaque reduction neutralization test (PRNT90) to investigate specific SARS-CoV-2 antibodies.…”
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Chemopreventive effects of vitamins in oral cancer by Dikshita Mehta, Leena Selvamary, Ramesh Kumar, Sujatha Anandan

“…The primary clinical outcome assessed was the reduction or elimination of premalignant lesions, particularly leukoplakia, which was reported in 90% of the trials. …”
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Enhanced rational protein engineering to reduce viscosity in high-concentration IgG1 antibody solutions by Tyler J. Lefevre, Jenna G. Caldwell, Austin Gallegos, Qun Du, Erin Houston, Gilad Kaplan, Reza Esfandiary

“…Several molecular-level challenges hinder the development of high concentration antibody drug products, including high viscosity caused by reversible self-association (RSA). Here, we take an enhanced rational design approach to reduce RSA via protein engineering. …”
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RNASET2 Deficiency Induces Hepatocellular Carcinoma Metastasis through Cholesterol‐Triggered MET Activation by Yanquan Xu, Yu Chen, Jiangang Zhang, Jingchun Wang, Shuai Yang, Huakan Zhao, Lei Wu, Juan Lei, Yu Zhou, Jin Peng, Lu Jiang, Qian Chen, Rong Xin, Jianyun Zhou, Yongsheng Li

“…However, the deficiency of RNASET2‐induced HCC metastasis can be reversed by blocking MET with shRNA or savolitinib. …”
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Targeting Zfp36 to combat cardiac hypertrophy: Insights into ferroptosis pathways by Mingyu Zhang, Xiaoxiang Guan, Zheng Dong, Chenxu Yang, Chao Xiong, Wenzheng Cheng, Aijing Shang, Yaru Liu, Xiaofei Guo, Bowen Zhang, Bo Zhang, Saidi Jin, Wenyi Qi, Berezhnova Tatjana Alexandrovna, Yuan Jiang, Zhimin Du, Chaoqian Xu

“…Methods and results Single‐cell sequencing analysis demonstrated a reduction in Zfp36 expression associated with cardiac hypertrophy. …”
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Sauchinone Ameliorates Senescence Through Reducing Mitochondrial ROS Production by Myeong Uk Kuk, Yun Haeng Lee, Duyeol Kim, Kyeong Seon Lee, Ji Ho Park, Jee Hee Yoon, Yoo Jin Lee, Byeonghyeon So, Minseon Kim, Hyung Wook Kwon, Youngjoo Byun, Ki Yong Lee, Joon Tae Park

“…Strategies to limit mitochondrial ROS production are considered important for reversing senescence, but effective approaches to reduce them have not yet been developed. …”
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Mitochondria targeted nanoparticles for the treatment of mitochondrial dysfunction-associated brain disorders by Amy Claire Buck, Amy Claire Buck, Gerald J. Maarman, Admire Dube, Soraya Bardien, Soraya Bardien, Soraya Bardien

“…All the NPs showed improved mitochondrial functioning including a reduction in reactive oxygen species (ROS) production, an improvement in overall mitochondrial respiration and a reversal of toxin-induced mitochondrial damage. …”
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The Mycobacterium ulcerans toxin mycolactone causes destructive Sec61-dependent loss of the endothelial glycocalyx and vessel basement membrane to drive skin necrosis by Louise Tzung-Harn Hsieh, Belinda S Hall, Jane Newcombe, Tom A Mendum, Sonia Santana Varela, Yagnesh Umrania, Michael J Deery, Wei Q Shi, Josué Diaz-Delgado, Francisco J Salguero, Rachel E Simmonds

“…Remarkably, exogenous addition of laminin-511 reduced endothelial cell rounding, restored cell attachment and reversed the defective migration caused by mycolactone. …”
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Optimization by Hydrogen Plasma Treatment of a-CH and Hydrogen/Nitrogen-Assisted a-CH Layers for SAW Sensors by Veronica Satulu, Mihai Paunica, Simona Brajnicov, Sorin Vizireanu, Gheorghe Dinescu, Bogdana Mitu, Cristian Viespe

“…The sensors demonstrated a reversible response to H₂S gas within 8 to 20 ppm concentration ranges, effectively detecting these levels. …”
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Global burden and cross-country inequalities in gallbladder and biliary tract cancer (1990–2021) with projections to 2050: insights from the global burden of disease study 2021 by Diya Xie, Fengmin Liu, Daosen Zhou, Qiang Zhu, Fangting Xiao, Kun Zhang

“…Unexpected polar reversal of gender differences warrants further attention.…”
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