Identification of HMOX-1-Targeting Natural Compounds in <i>Camellia nitidissima</i> Chi for NSCLC Therapy: Integrating Bioassay and In Silico Screening Approaches by Lingqiu Zhang, Fan Zhang, Haimei Liang, Xiangling Qin, Chunmei Liang, Manlu Zhong, Yuemi Mo, Jinling Xie, Xiaotao Hou, Jiagang Deng, Erwei Hao, Zhengcai Du

“…<b>Results:</b> The 95% F1 fraction from the extracts of <i>C. nitidissima</i> leaves exhibited the strongest anti-lung cancer activity, which could be significantly reversed by Ferrostatin-1. Furthermore, it induced typical ferroptosis-related structural damage in mitochondria, including shrinkage and a reduction in size, increased membrane density, and a reduction or even the disappearance of cristae structures. …”
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Unveiling polyoxometalate redox properties at the nanoscale by Volatron, Florence, Izzet, Guillaume, Vuillaume, Dominique,  Proust, Anna

“…They undergo successive, reversible, and highly adjustable mono- (or multi-) electronic reduction processes within a narrow range of potentials. …”
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Experimental Investigation on the Effects of Cutting Direction and Joint Spacing on the Cuttability Behaviour of a Conical Pick in Jointed Rock Mass by Han-Eol Kim, Min-Seong Kim, Wan-Kyu Yoo, Chang-Yong Kim

“…In parallel cutting, the joint plane acts as a barrier to side-crack propagation, leading to a further reduction in <i>FC</i>. The <i>FC</i> and specific energy (<i>SE</i>) were generally lower in parallel cutting than in perpendicular cutting. …”
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Simultaneous assessment of effects of variations in temperature and hydraulic retention time on membrane fouling in membrane bioreactors by Horieh Akbari, Hossein Hazrati, Abbas Nazmkhah, Hanieh Shokrkar

“…Ultimately, these changes led to reductions in both reversible and irreversible hydraulic resistances. …”
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Bovine colostrum-derived exosomes alleviate muscle degeneration by modulating gut microbiota and metabolic homeostasis in atrophy models by Minkyoung Kang, Bohyun Yun, Daye Mun, Sooah Kim, Kwangcheol Casey Jeong, Younghoon Kim, Sangnam Oh

“…These microbial changes were associated with a reduction in cholesterol levels in DEX-treated mice. …”
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Impact of Cochlear Trauma Degree and Localization on Intracochlear Electrocochleographic Recordings by David Bächinger, Merlin Schär, Ahmet Kunut, Rahel Bertschinger, Ivo Dobrev, Leanne Sijgers, Andreas H. Eckhard, Adrian Dalbert

“…Conclusions: These findings suggest that intracochlear ECochG can serve as a reliable intraoperative tool for detecting early and possibly reversible cochlear trauma, preventing more severe damage and aiding hearing preservation. …”
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Morphological change in an isolated population of red squirrels (Sciurus vulgaris) in Britain by Kim E. Chandler, Eloy Gálvez-López, Stuart Black, Andrew C. Kitchener, Kat Hamill, Bethan Roberts, Sean Doherty, Philip G. Cox

“…This effect was partially reversed following a reduction in supplementary feeding of peanuts. …”
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Honokiol protects against diabetic retinal microvascular injury via sirtuin 3-mediated mitochondrial fusion by Jiemei Shi, Jiemei Shi, Min Liu, Min Liu, Jiajie Zhao, Jiajie Zhao, Ye Tan, Chunhui Jiang, Chunhui Jiang

“…In vitro, HKL improved retinal capillary endothelial cell viability, decreased apoptosis, and reversed the HG-induced increased cellular oxidative stress and mitochondrial fragmentation. …”
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Loss of mitogen-activated protein kinase kinase kinase 4 (MAP3K4) reveals a requirement for MAPK signalling in mouse sex determination. by Debora Bogani, Pam Siggers, Rachel Brixey, Nick Warr, Sarah Beddow, Jessica Edwards, Debbie Williams, Dagmar Wilhelm, Peter Koopman, Richard A Flavell, Hongbo Chi, Harry Ostrer, Sara Wells, Michael Cheeseman, Andy Greenfield

“…Expression analysis of mutant XY gonads at the same stage also reveals a dramatic reduction in Sox9 and, crucially, Sry at the transcript and protein levels. …”
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S-ketamine alleviates depression-like behavior and hippocampal neuroplasticity in the offspring of mice that experience prenatal stress by Yan Zhang, Chu-Ke Wei, Ping Wang, Liu-Cheng Zheng, Yang Cheng, Zhen-Hua Ren, Yu-Hong Jin, Yu-You Yao, Huan-Zhong Liu

“…At the cellular level, S-ketamine markedly enhanced neuroplasticity in the CA1 hippocampus: Golgi-Cox staining showed that S-ketamine alleviated the reduction of neuronal complexity and dendritic spine density; Transmission electron microscopy indicated that S-ketamine reversed synaptic morphology alterations. …”
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Astaxanthin mitigates diabetic cardiomyopathy and nephropathy in HF/HFr/STZ diabetic rats via modulating NOX4, fractalkine, Nrf2, and AP-1 pathways by Nesma M.E. Abo El-Nasr, Yosra A. Hussien, Marawan Abd El-Baset, Marwa E. Shabana, Dalia O. Saleh

“…ECG abnormalities were partially reversed, with enhancements in the QTc interval and ST segment height. …”
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Recovery of Male Siamese Fighting Fish (<i>Betta splendens</i>) After Overland Shipping by Karun Thongprajukaew, Saowalak Malawa, Sukanya Poolthajit, Nutt Nuntapong, Waraporn Hahor

“…Ornamental fish shipped by road or rail may spend days in transit without food, leading to a reduction in somatic growth after transportation and during acclimatization. …”
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Biochemical and Structural Characterization of Glyoxylate Reductase/Hydroxypyruvate Reductase from <i>Bacillus subtilis</i> by Thang Quyet Nguyen, Thai Huu Duong, Jin Kuk Yang, Wonchull Kang

“…D-2-hydroxyacid dehydrogenases (2HADHs) catalyze the reversible reaction of 2-ketocarboxylic acid to the corresponding (R)-2-hydroxycarboxylic acids using NAD(P)H cofactor. …”
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Prevotella copri-mediated caffeine metabolism involves ferroptosis of osteoblasts in osteoarthritis by Feng Li, Xin Wen, Pu Xue, Huiping Xu, Panyang Wu, Zhiming Xu, Xianwei Wang, Guofu Pi

“…Caffeine exposure is responsible for the reduction of bone mass and restrained osteoblast function. …”
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The Effects of Lipid Extracts from Microalgae <i>Chlorococcum amblystomatis</i> and <i>Nannochloropsis oceanica</i> on the Proteome of 3D-Cultured Fibroblasts Exposed to UVA Radiat... by Sinemyiz Atalay Ekiner, Agnieszka Gęgotek, Maria Rosário Domingues, Pedro Domingues, Elżbieta Skrzydlewska

“…The results revealed that both lipid extracts effectively reversed the UVA-perturbed proteomic profile of fibroblasts, highlighting their therapeutic potential in protecting the skin from UV radiation.…”
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The effect of intravesical Bacillus Calmette-Guerin (BCG) treatment on sperm parameters in non-muscle-invasive bladder cancer patients by Sergen Sahin, Ismail Ulus, Ibrahim Ogulcan Canitez, Serhat Yentur, Mustafa Zafer Temiz, Atilla Semercioz

“…Post-treatment evaluation indicated a significant reduction in sperm concentration, total sperm count, progressive motility, and normal morphology (p < 0.05), alongside a notable increase in the percentage of immotile sperm. …”
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Epimorphin alters the inhibitory effects of SOX9 on Mmp13 in activated hepatic stellate cells. by James Pritchett, Varinder S Athwal, Emma Harvey, Katherine Martin, Jessica Llewellyn, Philip Ireland, Alexander Nicolaides, Martin J Humphries, Nicoletta Bobola, Neil A Hanley, Karen Piper Hanley

“…Although potentially reversible, treatment remains limited. Understanding how ECM influences the pathogenesis of the disease may provide insight into novel therapeutic targets for the disease. …”
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Investigating the Iron Plating and Stripping of Anolytes for All-Iron Redox-Flow Batteries by Marius Engler, Michael Stich, Christoph Baumer, Andreas Bund

“…The investigations demonstrate that complexing agents exert a detrimental influence on the kinetics of plating/stripping reactions, resulting in diffusivity reduction, while favouring hydrogen evolution reaction (HER). …”
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FTO-mediated demethylation of MTUS1/ATIP1 promotes tumor progression in head and neck squamous cell carcinoma by Dongxiao Tang, Congyuan Cao, Wuguo Li, Anxun Wang

“…Nevertheless, the underlying mechanism responsible for the reduction of MTUS1/ATIP1 expression has not been investigated. …”
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MATHEMATICS THROUGH LANGUAGE AND LANGUAGE THROUGH MATHEMATICS: CONDENSATION TRANSCRIPTION AS A POINT OF SYMBIOSIS by Janice Hill

“… This paper explores the idea of condensation transcription—which is defined as the reduction of lengthy collections of lexical elements or mathematical descriptions into short forms—as the point where mathematics and language learning cross-influence one another notably. …”
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