Conventional and neuropsychological criteria for mild cognitive impairment show similar prognostic value for dementia across 12 years in a non-clinical setting by Simone Galati, Michele Rossi, Federica Del Signore, Giulia Locatelli, Antonio Guaita, Elena Rolandi

“…Abstract Making early and informative diagnoses of mild cognitive impairment (MCI) is highly important for planning timely and appropriate interventions aimed at dementia risk reduction. However, there is currently no agreement on the MCI criteria, leading to wide heterogeneity in the prognosis of MCI patients and high reversion rates. …”
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HBIM-Based Multicriteria Method for Assessing Internal Insulation in Heritage Buildings by Angelo Massafra, Luca Mattioli, Iuliia Kozlova, Cecilia Mazzoli, Giorgia Predari, Riccardo Gulli

“…The methodology, tested on a building located in Bologna (Italy), allows for assessing internal insulation systems with varying thermophysical properties and performance characteristics, and evaluating how they affect space- and wall-level key performance indicators, including condensation risk, energy efficiency improvement, and usable space reduction. The research was conducted under the Horizon Europe HERIT4AGES project, which aims to develop reversible, innovative insulation panels fabricated from local and recycled materials for historic building retrofitting.…”
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Hippocampal gene expression changes associated with sequential behavioral training in a temporal lobe epilepsy rat model by Rudhab Bahabry, Silvienne Sint Jago, Rebecca M. Hauser, Jonathan Harmon, Leah Dinah Sheppard, Bellafaith Oyassan, Farah D. Lubin

“…Quantitative PCR (qPCR) analysis revealed an increase in BDNF, dFosB, Tet2, and Tet3 expression in the epilepsy-SBT group compared to control-SBT, while there was a reduction in Npas4 and Egr4 expression. Immunohistochemistry (IHC) showed that in epileptic animals, performing SBT reversed the loss of 5-hydroxymethylcytosine (5-hmC) in the dorsal hippocampus compared to that seen in home-caged (HC) epileptic animals, and this reversal was neuron-driven. …”
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Ocean acidification trends and carbonate system dynamics across the North Atlantic subpolar gyre water masses during 2009–2019 by D. Curbelo-Hernández, F. F. Pérez, M. González-Dávila, S. V. Gladyshev, A. G. González, D. González-Santana, A. Velo, A. Sokov, J. M. Santana-Casiano

“…The ocean acidification (OA) patterns and the reduction in the saturation state of calcite (<span class="inline-formula">Ω_Ca</span>) and aragonite (<span class="inline-formula">Ω_Arag</span>) in response to the increasing anthropogenic CO<span class="inline-formula">₂</span> (<span class="inline-formula"><i>C</i>_ant</span>) were assessed within the Irminger, Iceland, and Rockall basins during a poorly assessed decade in which the physical patterns reversed in comparison with previous well-known periods. …”
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Palmitoylation regulates epidermal homeostasis and hair follicle differentiation. by Pleasantine Mill, Angela W S Lee, Yuko Fukata, Ryouhei Tsutsumi, Masaki Fukata, Margaret Keighren, Rebecca M Porter, Lisa McKie, Ian Smyth, Ian J Jackson

“…Unlike other lipid modifications, palmitoylation is reversible and thus often regulates dynamic protein interactions. …”
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Altered Respiratory Physiology in Obesity by Krishnan Parameswaran, David C Todd, Mark Soth

“…Whether obesity contributes to asthma and airway hyper-responsiveness is uncertain. Weight reduction and physical activity are effective means of reversing the respiratory complications of obesity.…”
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The TIP60-CD44 Axis Modulates Colorectal Cancer Stemness by Asad Mohammad, Sudhakar Jha

“…Mechanistically, the reduction of TIP60 resulted in a decrease in <i>CD44</i> expression, a critical marker for cancer stem cells (CSCs). …”
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Brivaracetam to Treat Partial Onset Seizures in Adults by Dustin Latimer, David Le, Evan Falgoust, Patrick Ingraffia, Alaa Abd-Elsayed, Elyse M. Cornett, Rupin Singh, JooHee Choi, Giustino Varrassi, Adam M. Kaye, Alan D. Kaye, Latha Ganti

“…A meta-analysis in 2016 showed that brivaracetam as adjunctive therapy was statically significant in its reduction of adults with drug-refractory seizure frequency.^1^ The most commonly reported adverse effects that patients who were taking brivaracetam experienced were somnolence, headache, and dizziness. …”
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Tomosyn inhibits synaptic vesicle priming in Caenorhabditis elegans. by Elena O Gracheva, Anna O Burdina, Andrea M Holgado, Martine Berthelot-Grosjean, Brian D Ackley, Gayla Hadwiger, Michael L Nonet, Robby M Weimer, Janet E Richmond

“…However, at the ultrastructural level, we observe a concomitant increase in the number of plasma membrane-contacting vesicles in tom-1 mutant synapses, a phenotype reversed by neuronal expression of TOM-1. Priming defective unc-13 mutants show a dramatic reduction in plasma membrane-contacting vesicles, suggesting these vesicles largely represent the primed vesicle pool at the C. elegans neuromuscular junction. …”
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Cucurbita maxima Seeds Reduce Anxiety and Depression and Improve Memory by Shahana Wahid, Ali Alqahtani, Rafeeq Alam Khan

“…Motor skilled learning was assessed by stationary rod and rotarod apparatus. Reversed phase high-pressure liquid chromatography was used to determine biogenic amine levels. …”
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Recurrence of Postoperative Stress-Induced Cardiomyopathy Resulting from Status Epilepticus by Grant A. Miller, Yousef M. Ahmed, Nicki S. Tarant

“…Temporary reduction in ejection fraction (EF) resolves spontaneously. …”
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Changes in Polarity and Regeneration-Related Gene Expression in In Vitro Bone Marrow Mesenchymal Stem Cells in a Rheumatoid Arthritis Injury Model and Pharmacological Modulation by Muhammet Ocak

“…Results: As a result of the analyses, as expected, IL-1β and IL-6 caused a reduction in viability and an acceleration in cytotoxicity in human bone marrow stem cells imitating RA damage. …”
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Phagocytosis of mast cell granules results in decreased macrophage superoxide production by Bobby A. Shah, Yuai Li, Daniel J. Stechschulte, Kottarappat N. Dileepan

“…Co-incubation of macrophages with either intact MCGs or MCG-sonicate resulted in a dose-dependent inhibition of superoxide- mediated cytochrome c reduction. This inhibitory effect was evident within 5 min of incubation and with MCG-sonicate was completely reversed when macrophages were washed prior to activation with PMA. …”
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Unraveling reaction discrepancy and electrolyte stabilizing effects of auto‐oxygenated porphyrin catalysts in lithium–oxygen and lithium–air cells by Boran Kim, Hyunyoung Park, Hyun‐Soo Kim, Jun Seo Lee, Jongsoon Kim, Won‐Hee Ryu

“…However, the slow oxygen reduction and evolution reactions interfere with reversible cell operation during cycling. …”
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Cyclic Voltammetry Study of the Influence of Concentration of K3[Fe(CN)6] and Glucose on Glassy Carbon Electrode by Adella Fajaretta Gunawan, Arie Hardian, Anceu Murniati

“…GCE characterization utilized K3[Fe(CN)6] solutions (1 – 5 mM) in 0.2 M KCl and achieved an optimum scan rate of 75 mV/s within -1.5 to 1 V vs. Ag/AgCl. Reversible Fe2+/Fe3+ redox occurred at 1mM (ipa/ipc= 0.99), with the highest reduction peak at 5mM. …”
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Effect of ellagic acid on BDNF/PI3K/AKT-mediated signaling pathways in mouse models of depression by Aslı Bedel, Coskun Usta

“…Results: Sertraline and EA provided a reduction in immobility time in the tail suspension test when compared with the control group. …”
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Risk of Fatal Bleeding in Episodes of Major Bleeding with New Oral Anticoagulants and Vitamin K Antagonists: A Systematic Review and Meta-Analysis. by Joel Skaistis, Travis Tagami

“…<h4>Background</h4>The reversibility of new/novel oral anticoagulants (NOAC) is not well understood, whereas the reversal strategies for bleeding associated with vitamin k antagonists (VKA), such as warfarin, is well established. …”
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Paeoniflorin Ameliorates Hyperprolactinemia-Induced Inhibition of Osteoblastogenesis by Suppressing the NF-κB Signaling Pathway by Xiaohong Sun, Keda Zhu, Chengcheng Feng, Jie Zhu, Shuangshuang Chen, Wenkai Tang, Zhifang Wang, Long Xiao, Hong Li, Dechun Geng, Zhirong Wang

“…In addition, our findings proved that paeoniflorin increased the absorbance values of ALP-positive cells and the areas of alizarin red S (ARS) deposition compared to those in the prolactin group, suggesting that paeoniflorin reversed the PRL-induced reduction in osteoblast differentiation. …”
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Prevention of hypovolemic circulatory collapse by IL-6 activated Stat3. by Jeffrey A Alten, Ana Moran, Anna I Tsimelzon, Mary-Ann A Mastrangelo, Susan G Hilsenbeck, Valeria Poli, David J Tweardy

“…HCC in this model was accompanied by a 50% reduction in peak acceleration of aortic blood flow and cardiomyocyte apoptosis. …”
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Staurosporine Induces the Generation of Polyploid Giant Cancer Cells in Non-Small-Cell Lung Carcinoma A549 Cells by Alexander Glassmann, Carmen Carrillo Garcia, Viktor Janzen, Dominik Kraus, Nadine Veit, Jochen Winter, Rainer Probstmeier

“…Cultivation of A549 non-small-cell lung carcinoma (NSCLC) cells in the presence of staurosporine (SSP) leads to a reduction or a lack of proliferation in a concentration-dependent manner. …”
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