Cumulative effects of natural and anthropogenic processes on groundwater chemistry of a small karst island—case study of Vis (Croatia) by Matko Patekar, Maja Briški, Josip Terzić, Zoran Nakić, Staša Borović

“…Consequently, in the last decade, occasional reductions for consumers occurred. Monitoring of in situ physicochemical parameters and groundwater sampling for chemical and isotopic analyses were conducted from 2020 to 2023 at deep borewells, shallow dug wells, and springs. …”
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Guanylate cyclase promotes osseointegration by inhibiting oxidative stress and inflammation in aged rats with iron overload by Zhou-Shan Tao, Cai-Liang Shen

“…The observed effects were concomitant with reductions in bone metabolism, oxidative stress, and inflammation. …”
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UP-FRONT TRIPLE COMBINATION THERAPY FOR PULMONARY ARTERIAL HYPERTENSION ASSOCIATED WITH SYSTEMIC SCLEROSIS: A CASE REPORT by A. V. Volkov, N. N. Yudkina, E. V. Nikolaeva, I. A. Kurmukov

“…Thirty-month therapy resulted in a reversal of FC from IV to II, relieved the signs of right ventricular failure, complete right ventricular reverse remodeling and subnormalization of hemodynamic parameters. …”
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Gibberellin Is Involved in Inhibition of Cucumber Growth and Nitrogen Uptake at Suboptimal Root-Zone Temperatures. by Longqiang Bai, Huihui Deng, Xiaocui Zhang, Xianchang Yu, Yansu Li

“…Exposure of cucumber seedlings to a Tr of 16°C led to a significant reduction in root growth, and this inhibitory effect was reversed by exogenous application of GA. …”
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Early daratumumab therapy improves renal outcomes in newly diagnosed patients with myeloma admitted with kidney injury by E. Bridget Kim, Jack E. Malespini, Matthew Lei, Samuel S. Han, Cole W. Minsky, Andrew R. Branagan, Elizabeth K. O’Donnell, Diana Cirstea, Noopur S. Raje, Andrew J. Yee

“…Of 17 patients, 15 (88%) achieved sFLC reduction ≤500 mg/L after 1 cycle of treatment. The median time to sFLC reduction ≤500 mg/L was 14.5 days (95% CI, 9-49). …”
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Fumarprotocetraric acid and geraniin were identified as novel inhibitors of human respiratory syncytial virus infection in vitro by Chao Wang, Chao Wang, Yi-Man Huang, Yi-Man Huang, Jun Zhao, Jun Zhao, Yi-Ming Bai, Yi-Ming Bai, Cai-Qin Yan, Cai-Qin Yan, Guan-Hua Du, Guan-Hua Du, Li-Shu Zheng, Li-Shu Zheng, Ai-Lin Liu, Ai-Lin Liu

“…The antiviral effect of fumarprotocetraric acid (FUM) and geraniin (GE) were confirmed by Real-time reverse transcription quantitative PCR (Real-time RT-PCR), plaque reduction test, immunofluorescence assay, and Western blot analysis. …”
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A strain of Lactobacillus plantarum from piglet intestines enhances the anti-PoRV effect via the STING-IFN-I pathway by Anqi Sun, Xin Shan, Ruihan Liu, Zhengxu Tang, Jingshu Huang, Shihan Zhang, Lihong Bian, Yumeng Shi, Zixuan Liu, Jingtao Hu, Chunfeng Wang

“…Consistent findings were observed in intestinal tissues of LP1-protected mice with STING pathway activation correlating with reduction in viral titers. Crucially, STING inhibitor (C-170) administration could reverse LP1-mediated antiviral effects. …”
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Astaxanthin ameliorates benzalkonium chloride–induced dry eye disease through suppressing inflammation and oxidative stress via Keap1‐Nrf2/HO‐1 signaling pathways by Ziyu Liu, Yaqiong Li, Jiayu Bao, Siyuan Li, Ya Wen, Peng Zhang, Jun Feng, Yinghui Wang, Lei Tian, Ying Jie

“…Results Network pharmacology suggests that AST may alleviate DED by influencing oxidation–reduction signaling pathways and reducing oxidative stress provoked by BAC. …”
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Knockdown of lncRNA XR_877193.1 suppresses ferroptosis and promotes osteogenic differentiation via the PI3K/AKT signaling pathway in SONFH by Yang Huixia, Ding Ning, Qing Shi, Hao Yinju, Zhao Cilin, Wu Kai, Li Guizhong, Zhang Huiping, Ma Shengchao, Bai Zhigang, Jiang Yideng

“…Importantly, the ferroptosis inhibitor ferrostatin-1 (Fer-1) effectively reverses Dex-induced ferroptosis in MC3T3-E1 cells. …”
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Study of the effect of the herbal composition SR2004 on hemoglobin A1c, fasting blood glucose, and lipids in patients with type 2 diabetes mellitus by Sumit Chatterji, Dov Fogel

“…At 12 weeks, HbA1c reduced from 9.0% to 7.1% (22%; p < 0.0001), mean blood glucose decreased from 211 mg/dL to 133 mg/dL (37% reduction; p < 0.0001), mean total cholesterol to 185 mg/dL (13% reduction; p < 0.01) and mean serum triglycerides to160 mg/dL (a reduction of 40% from baseline; p < 0.001). …”
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The impact of digital industries on carbon emission in China: Input-output and structural decomposition analysis by Yuke Li, Jing Wu, Xiaodong Pei, Qianting Zhu

“…The results show that: (1) embodied carbon emissions of DI show an upward trend, and the indirect carbon emissions are much higher than the direct carbon emissions; (2) the structural effects of DI contribute to a total reduction of -45.68 Mt in China's carbon emissions, but the structural effects of DI on embodied carbon emissions show significant regional heterogeneity, and the carbon emissions in Jiangsu, Shanghai, Hubei, and other provinces have obvious changes; (3) the structural effects of DI primarily affect carbon emissions in the industrial and service sectors, in the early stage, the structural effects of DI led to an increase in the carbon emissions of the industrial sectors and a decrease in the service sectors, however, in recent years, the trend reversed; (4) based on the development level of DI and the structural effects of DI on carbon emissions in each industry, 30 provinces, autonomous regions, and municipalities in China can be classified into five categories, and tailored emission reduction strategies should be implemented in different provinces. …”
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A systematic review on natural products with antimicrobial potential against WHO’s priority pathogens by SeyedAhmad SeyedAlinaghi, Esmaeil Mehraeen, Pegah Mirzapour, Soudabeh Yarmohammadi, Soheil Dehghani, Sarina Zare, Shayan Gholami, Niloofar Attarian, Amene Abiri, Farid Farahani Rad, Amir Tabari, Fatemeh Afroughi, Amirhossein Gholipour, Mohammad Mahdi Roozbahani, Shayesteh Jahanfar

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Targeting CD38 in Antibody-Mediated Rejection by Katharina A. Mayer, Klemens Budde, Matthias Diebold, Matthias Diebold, Philip F. Halloran, Georg A. Böhmig

“…Previous case reports and series suggested that off-label daratumumab treatment could effectively reverse AMR. Felzartamab has now demonstrated safety and efficacy in a phase 2 trial for late AMR. …”
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Insights into the role of miR-877 and histidine-rich glycoprotein in preeclampsia by Eman Khairy, Abeer Zakariyah, Rimah Saleem, Hosam Hemeda, Mai Nabil

“…However, there were significant reductions in HRG serum levels along with significant increases in placental HRG levels among patients with PE. …”
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Transition Metal Complexes of Naproxen: Synthesis, Characterization, Forced Degradation Studies, and Analytical Method Verification by Md. Sharif Hasan, Ruhul Kayesh, Farida Begum, S. M. Abdur Rahman

“…Complexes were subjected to acidic, basic, and aqueous hydrolysis as well as oxidation, reduction, and thermal degradation. Also the reversed phase high-performance liquid chromatography (RP-HPLC) method of Naproxen outlined in USP was verified for the Naproxen-metal complexes, with respect to accuracy, precision, solution stability, robustness, and system suitability. …”
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The effects of smoking, alcohol consumption, obesity, and physical inactivity on healthcare costs: a longitudinal cohort study by Younhee Kim

“…Former smokers had lower costs than current smokers, with reductions of 9.9% for males and 13.2% for females. …”
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Androgen receptor activation inhibits endothelial cell migration in vitro and angiogenesis in vivo by Yen-Nien Huo, Hsiang-Yu Yang, Hung-Yen Ke, Chih-Yuan Lin, Chien-Sung Tsai

“…Our data demonstrates that treatment of human umbilical vein endothelial cells (HUVECs) with AR agonists, metribolone (R1881) or dihydrotestosterone (DHT), results in a dose-dependent reduction in migration, which can be reversed by AR antagonists or AR knockdown. …”
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Nutraceutical COMP-4 confers protection against endothelial dysfunction through the eNOS/iNOS-NO-cGMP pathway. by Monica G Ferrini, Andrea Abraham, Revecca Millán, Leslie Graciano, Sriram V Eleswarapu, Jacob Rajfer

“…Co-incubation of COMP-4 with H2O2 reversed detrimental effects of H2O2 on endothelial function, evidenced by improvement in NO availability and abrogation of the pro-inflammatory milieu. …”
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In Vivo Antimalarial Activity of Leaf Latex of Aloe melanacantha against Plasmodium berghei Infected Mice by Gebrehiwot Kiros Gebremariam, Haile Kassahun Desta, Tekleab Teka Teklehaimanot, Tsgab Gebrecherkos Girmay

“…The latex also reversed the PCV reduction significantly (P<0.05) at 200 mg/kg and 400 mg/kg doses and prevented rectal temperature dropping significantly (P<0.05) at all doses. …”
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Electron deficient nanoclusters of platinum and palladium on porous silicon by N. A. Yashtulov

“…The platinum and palladium nanoparticles on the porous silicon were synthesized by radiation - chemical reduction in the solution of reversed micelles. The Pt and Pd nanoclusters obtained are electron deficient.…”
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