Propofol protects against high glucose-mediated endothelial injury via inhibition of COX2 and iNOS expressions by Shao Jiayun, Ding Juan, Lu Lihong, Hou Wenting, Wang Fei, Sun Zhirong, Jiang Hui, Zhao Yanjun

“…High glucose increases the abundance of SP1 bound to the ELF3 promoter, which can be reversed by propofol treatment. The protective effect of propofol is reversed by SP1 overexpression. …”
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Alcohol drinking cessation and the risk of laryngeal and pharyngeal cancers: a systematic review and meta-analysis. by Aliasghar Ahmad Kiadaliri, Johan Jarl, Georgios Gavriilidis, Ulf-G Gerdtham

“…On average, alcohol drinking cessation was associated with a 2% yearly reduction in the risk of developing laryngeal and pharyngeal cancers. …”
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A novel obfuscation method based on majority logic for preventing unauthorized access to binary deep neural networks by Alireza Mohseni, Mohammad Hossein Moaiyeri, Mohammad Javad Adel

“…The proposed approach yields 43%, 79%, and 71% reductions in area, average power, and weight modification energy per filter in the neural network structures. …”
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hBMSC-EVs alleviate weightlessness-induced skeletal muscle atrophy by suppressing oxidative stress and inflammation by Mengyuan Chang, Ruiqi Liu, Bingqian Chen, Jin Xu, Wei Wang, Yanan Ji, Zihui Gao, Boya Liu, Xinlei Yao, Hualin Sun, Feng Xu, Yuntian Shen

“…Moreover, intravenous administration of hBMSC-EVs at a concentration of 1 × 1010 particles/mL can effectively reverse the reduction in soleus mass (P < 0.001), CSA (P < 0.01), and grip strength (P < 0.001) in mice caused by weightlessness. …”
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Prepregnancy Obesity Reprograms Offspring Skeletal Muscle Fibre Transition Through H3K9me3 by Yichi Wu, Sujuan Li, Jingyi Zhang, Anran Tian, Xiangyao Wang, Xi Yang, Fucheng Meng, Qing Li, Yuan Gao, Yingying Li, Furong Liang, Minglan Yao, Xiaoping Luo, Cai Zhang

“…Results Male and female offspring of prepregnancy obese dams (mHFD) exhibited a significant reduction in slow‐twitch oxidative fibres (p < 0.001) and an increase in fast‐twitch glycolytic fibres compared with controls. …”
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Sustained natural immunity following SARS-CoV-2 infection against severe COVID-19 outcomes and symptomatic reinfection: analyses of national data for Brazil and Scotland by Aziz Sheikh, Neil Pearce, Mauricio L Barreto, Chris Robertson, Srinivasa Vittal Katikireddi, Syed Ahmar Shah, Kirsten J Hainey, Thiago Cerqueira-Silva, Manoel Barral-Netto, Tristan Millington, Fasih Haider, Vincius de Araujo Oliveira, Viviane Sampaio Boaventura

“…Reinfection was defined as reverse-transcriptase PCR or rapid antigen test confirmed at least 120 days after primary infection.Results From Brazil, we included 30 881 873 tests and 1 301 665 severe COVID-19 outcomes, and from Scotland, we included 1 520 201 tests and 7988 severe COVID-19 outcomes. …”
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Defective Cystic Fibrosis Transmembrane Conductance Regulator Accelerates Skeletal Muscle Aging by Impairing Autophagy/Myogenesis by Ziyi Chen, Jiankun Xu, Peijie Hu, Wanting Du, Junjiang Chen, Xiaotian Zhang, Wei Zhou, Jiayang Gao, Yuantao Zhang, Bingyang Dai, Guangshuai Nie, Jun Hu, Liangbin Zhou, Shunxiang Xu, Hisao Chang Chan, Wing‐hoi Cheung, Ye Chun Ruan, Ling Qin

“…Conclusion Age‐related reduction in skeletal muscle expression of CFTR impairs autophagy and myogenesis, exacerbating skeletal muscle aging. …”
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Circ‐myh8/KAT7 Affects PANoptosis in Pulmonary Arterial Smooth Muscle Cells: Involvement of Super‐Enhancers in FOSL2 Expression by Jingya Zhang, Xinru Wang, Xu Wang, Songyue Li, Jianli Hou, Yibin Zhang, Xinyue Song, Shukun Cao, Ya Xu, Jing Qi, Baoshan Zhao, Xiaodong Zheng, Yan Xing

“…CRISPR‐Cas9‐mediated knockdown of the FOSL2 SE resulted in a reduction in PANoptosis in PASMCs. Additionally, ChIP‐polymerase chain reaction assays revealed that FOSL2 functions as a transcription factor that binds to the promoters of PANoptosis‐related genes. …”
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Effect of Sunflower (Helianthus annus L.) Hulls with Different Particle Sizes on Growth Performance and Physiological Responses of Broiler Chickens Fed Different Levels of Protein by Najibeh Beigzadeh, Smayyeh Salari, Faegheh Zaefarian, Shima Hosseinifar

“…A well-developed gizzard also enhances reverse peristalsis, which churns food back up the digestive tract. …”
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The role of adipose-derived stem cells in knee osteoarthritis treatment: insights from a triple-blind clinical study by Simin Sajadi, Mohammad Amin Khadembashiri, Gholamreza Raissi, Mohamad Mehdi Khadembashiri, Korosh Mansouri, Homayoun Hadizadeh-Kharazi, Mohammad Taghi Joghataei, Seyed Pezhman Madani, Bijan Forogh, Sina Parsipour

“…Despite its prevalence, no medical treatment can reverse the joint cartilage degradation, leading many patients to undergo invasive procedures such as arthroplasty. …”
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If you are for market creation, you should be for market destruction! Ethics and the relations between exnovation and innovation for changing direction by Lukas Fuchs, Rafael Ziegler

“…In addition, we show that they support an independent focus on exnovation, where the latter relies on reversion to old technologies or on overall reduction of economic activity. …”
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The Impact of COVID-19 on DTP3 Vaccination Coverage in Europe (2012–2023) by Ines Aguinaga-Ontoso, Sara Guillen-Aguinaga, Laura Guillen-Aguinaga, Rosa Alas-Brun, Miriam Guillen-Aguinaga, Luc Onambele, Enrique Aguinaga-Ontoso, Esperanza Rayón-Valpuesta, Francisco Guillen-Grima

“…Background: The COVID-19 pandemic disrupted routine child immunization efforts, threatening to reverse progress in controlling vaccine-preventable diseases. …”
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Vasoprotective Effects of Hyperoside against Cerebral Ischemia/Reperfusion Injury in Rats: Activation of Large-Conductance Ca2+-Activated K+ Channels by Wen-Ming Hong, Yue-Wu Xie, Meng-Yu Zhao, Tian-Hang Yu, Li-Na Wang, Wan-Yan Xu, Shen Gao, Hua-Bao Cai, Yan Guo, Fang Zhang

“…Furthermore, the protective effect against I/R-induced increases of MDA and reduction of SOD as well as CBF induced by Hyp was significantly reversed by iberiotoxin (IbTX). …”
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INTERFERENCE OF ALUMINIUM WITH CARBOHYDRATE METABOLISM IN MALE RATS: A MODEL STUDY OF DIALYSIS PATIENTS

“…Daily injections of 2mgkg aluminium without citrate led to the reduction of liver glycogen by 60 percent, whereas if aluminium (2mg/kg) is injected in complex with citric acid this effect is reversed. …”
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The impact of frailty syndrome on skeletal muscle histology: preventive effects of exercise by Fujue Ji, Hae Sung Lee, Haesung Lee, Jong‐Hee Kim

“…Frailty syndrome led to increased body weight and ECM content, coupled with reductions in myofiber size and number, reflecting substantial structural and functional impairments in skeletal muscle. …”
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Towards net-zero in steel production: Process simulation and environmental impacts of carbon capture, storage and utilisation of blast furnace gas by Harish K. Jeswani, Santiago Zapata-Boada, Vincenzo Spallina, Adisa Azapagic

“…The results indicate that the CCU-based scenarios can reduce the climate change impact of steel production by 11–45 %, while the CCS scenarios can achieve reductions of 17–34 %. However, these reductions come with significant increases in other environmental impacts. …”
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Randomised, placebo-controlled, double-blinded trial of fecal microbiota transplantation in severe obesity: a study protocol by Rasmus Goll, Per-Christian Valle, Hege Marie Hanssen, Maria Serafia Fjellstad, Linn Skjevling, Peter Holger Johnsen, Kristin Helen Almå

“…Conservative treatment has a low success rate, and bariatric surgery is typically not reversible, with the risk of complications and recurrences. …”
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Cyclic Voltammetry of Human Dimeric Cystathionine by Sebastián Carballal, Fernando Zinola, Ruma Banerjee and Beatriz Alvarez

“…In this study, we have assessed the redox behavior of CBS by direct electrochemistry and we have estimated its reduction potential by cyclic voltammetry. Human dimeric CBS, a variant lacking the C-terminal domain, showed a quasi-reversible response on a platinum electrode, with anodic and cathodic peaks at -0.325 V and -0.454 V vs NHE, respectively, yielding an estimated formal reduction potential of -0.158 V vs NHE at pH 6.46. …”
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Cranial radiation disrupts dopaminergic signaling and connectivity in the mammalian brain by Die Zhang, Riya Thomas, Thanh Thai Lam, Ines Veselinovic, David R. Grosshans

“…These findings pave the way for novel research to prevent or reverse radiation-induced injury, ultimately improving the quality of life for brain tumor survivors.…”
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Stochastic Effect of Grain Elongation on Nanocrystalline Materials Strain and Strain Rate Produced by Accumulative Roll-Bonding and Equal Channel Angular Pressing by P. Baonhe Sob, A. Alfayo Alugongo, T. Ba Bob Tengen

“…The varying approaches of measuring grain radius reveal a common trend of Hall-Petch and Reverse Hall-Petch Relationship but with different critical grain sizes. …”
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