Hantaan virus infection induces human mucosal-associated invariant T cell pyroptosis through IRE1α pathway by Yusi Zhang, He Liu, Dalu Liu, Huiyuan Zhang, Ying Ma, Na Li, Chunmei Zhang, Manling Xue, Fenglan Wang, Xiaozhou Jia, Hui Zhang, Kang Tang, Xiaoyue Xu, Shijia Wang, Yiwen Wei, Xiaojing Yang, Jiajia Zuo, Lihua Chen, Boquan Jin, Yun Zhang

“…ER-stress inhibitor can reverse the pyroptosis of MAIT cells during HTNV infection. …”
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Air-gap membrane distillation to desalinate seawater and hypersaline-produced water by Prashan M. Rodrigo, Sana Fatima, Raghava R. Kommalapati, Shankararaman Chellam

“…This research tracked the real-time flux reduction with three distinct saline-level water matrices and assessed the permeate water quality. …”
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Nerve injury inhibits Oprd1 and Cnr1 transcription through REST in primary sensory neurons by Ashok Subedi, Asieh Etemad, Aadhya Tiwari, Yuying Huang, Biji Chatterjee, Samantha M. McLeod, Yungang Lu, DiAngelo Gonzalez, Krishna Ghosh, Mario Sirito, Sanjay K. Singh, Elisa Ruiz, Sandra L. Grimm, Cristian Coarfa, Hui-Lin Pan, Sadhan Majumder

“…Full-length Rest conditional knockout in primary sensory neurons reduced SNI-induced pain hypersensitivity and rescued the SNI-induced reduction in the expression of Oprd1 and Cnr1 in mouse DRG. …”
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Changes of NT-proBNP and sST2 levels for predicting isolated episodes of ventricular tachyarrhythmias and electrical storm in patients with systolic heart failure and various impla... by A. Zh. Gasparyan, E. V. Guseva, G. S. Tarasovsky, S. Yu. Kashtanova, M. D. Utsumueva, T. V. Sharf, N. A. Mironova, S. F. Sokolov, V. P. Masenko, A. A. Skvortsov, N. B. Shlevkov

“…The results obtained indicate that NT-proBNP and sST2 assessment in patients with systolic heart failure is promising for predicting isolated VTA, but not ES. Cardiac reverse remodeling as a result of effective CRT or CCM therapy is associated with a significant risk reduction for isolated VTA and ES.…”
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Gut cannabinoid receptor 1 regulates alcohol binge-induced intestinal permeability by Bin Gao, Luca Maccioni, George Kunos, Szabolcs Dvorácskó, Grzegorz Godlewski, Resat Cinar, Malliga R Iyer

“…Mechanistically, we found that alcohol activated intestinal epithelial CB1R-ERK1/2 pathway with subsequent downregulation of tight junction proteins and reduction in villi length. In addition, targeting intestinal CB1R and downstream ERK1/2 was able to reverse this process, with subsequent upregulation of tight junction proteins and increased villi length, thus improving gut barrier function. …”
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Telomere attrition alters extracellular vesicles conferring adverse impacts on neuronal viability and inflammatory response by Yi Gong, Yunong Wang, Francheska Delgado-Peraza, Carlos Nogueras-Ortiz, Nicole Noren Hooten, Deborah L. Croteau, Mithlesh Temre, Abigail E. Molnar, Monica Bodogai, Ainslee Zou, Kotb Abdelmohsen, Wei Zhu, Yongqing Zhang, Myriam Gorospe, Nan-Ping Weng, Michele K. Evans, Dimitrios Kapogiannis, Yie Liu

“…In generation 3 (G3) Tert−/−mice with shortened telomeres, we observed a significant reduction in plasma EV concentration and tissue-specific changes in EV levels and telomeric DNA content. …”
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Type 2C Protein Phosphatase MoPtc6 Plays Critical Roles in the Development and Virulence of <i>Magnaporthe oryzae</i> by Frankline Otieno Jagero, Abah Felix, Yakubu Saddeeq Abubakar, Meilian Chen, Wilfred M. Anjago, Hatungimana Mediatrice, Nkurikiyimfura Oswald, Osakina Aron, Wei Tang, Zonghua Wang, Jules Biregeya

“…Deletion of <i>MoPTC6</i> led to a drastic reduction in conidiophore development, conidia production, hyphal growth, and stress tolerance. …”
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Relationship between advanced lung cancer inflammation index and all-cause and cause-specific mortality among chronic inflammatory airway diseases patients: a population-based stud... by Zhuanbo Luo, Peixu Chen, Shiyu Chen, Xue Kong, Hongying Ma, Chao Cao

“…For ALI values below 99, a 10-unit rise in ALI was linked to a 14% reduction in the risk of all-cause mortality (HR: 0.86, 95% CI:0.81-0.92, Ptrend=0.01). …”
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GABAB receptor activation contributes to post-surgery cognitive impairments in mice by inducing hippocampal BDNF hypermethylation by Tong Wu, Xiao-Yu Sun, Jing Cao, Kun Tong, Jing-Ru Hao, Nan Sun, Can Gao

“…Our findings suggest that inhibition of GABAB receptor activation to reverse BDNF hypermethylation may represent a potential therapeutic strategy for alleviating PND.…”
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Does outward foreign direct investment improve environmental quality in home country?——Evidence from Chinese firms’ water pollution emissions by Suhua Tian, Qin Xiong

“…The mechanism analysis suggests that firms primarily attain emission reductions through reverse technology spillovers stemming from OFDI in host countries with more stringent environmental regulations. …”
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RATE CONSTANTS FUR THE ELECTRODE REACTIONS OF QUINONES IN CHLOROFORM: THE DEPENDENCE ON ELECTRODE MAmRIAL,S AND APPARENT STANDARD POENTIALS

“…The results obtained from this study reveal that the reduction of the quinones is two one-electron processes, the first reduction to the serniquinone anion radical is nearly reversible and the second to the dianion is quasireversib'te. …”
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Antisense oligonucleotides targeting the SARS-CoV-2 nucleocapsid gene decrease viral titers in hamsters by Christopher Fitzpatrick, Nicolas Meunier, Sophie Lepoder, Sophie Dhorne-Pollet, Bruno Da Costa, Bernard Klonjkowki, Jean-François Eléouët, Verónica A. Burzio, Bernard Delmas, Eric Barrey

“…ASO-N1 induced a sustained reduction in viral RNA and inflammatory cytokine expression in the nasal mucosa and efficiently decreased infectious viral titers in nasal swabs at day 3 post infection. …”
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Brucella secretory protein VceA promotes FOXO1 entry into the nucleus to shift host cell metabolism toward glycolysis by Cao Shuzhu, Han Xinxin, Deng Xingmei, Guo Jia, Liu Liangbo, Zhang Yu, Suleimenov Maratbek, Zhao Tianyi, Li Wei, Ding Jian, Xie Songsong, Zhang Hui

“…Conversely, in a VceA mutant strain (S2308-ΔVceA), we note a significant reduction in the ability of FOXO1 to enter the nucleus, accompanied by a decrease in glycolysis level. …”
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Doxycycline-Induced Apoptosis in Brucella suis S2-Infected HMC3 Cells via Calreticulin Suppression and Activation of the IRE1/Caspase-3 Signaling Pathway by Wang Z, Yang J, Zhang DE, Qiao X, Yang SL, Wang ZH, Yang Q

“…The same parameters were measured in B. suis S2-infected HMC3 cells following treatment with 160 μM Dox.Results: Treatment with 160 μM Dox for 12 hours resulted in a reduction in CALR protein levels and the induction of apoptosis in HMC3 cells. …”
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Association between lncRNA H19 and osteoporosis in postmenopausal patients with type 2 diabetes mellitus by Teng Yang, Xiuli Feng, Na Wang, Tongyu Zhang, Zhichen Zheng, Guofeng Wang

“…Clinical data and laboratory parameters were collected, and quantitative reverse transcription polymerase chain reaction (qRT-PCR) was used to quantitatively determine the expression of lncRNA H19 in PBMCs. …”
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A biomass-driven polygeneration system for electricity, cooling, and desalinated water: Exergoeconomic analysis and multi-objective optimization by Ehsanolah Assareh, Aminhossein Jahanbin, Seyed Mohammad Salehan, Ehsan Darouneh, Umberto Berardi

“…The proposed configuration combines a modified Brayton cycle (BC), reverse osmosis (RO) desalination unit, steam Rankine cycle (SRC), absorption chiller, and thermoelectric generator (TEG), which recovers waste heat from biomass combustion to enhance overall efficiency. …”
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Bovine lactoferrin alleviates aflatoxin B1 induced hepatic and renal injury in broilers by mediating Nrf2 signaling pathway by Hong Chen, Jameel Ahmed Buzdar, Roshan Riaz, Dalia Fouad, Nisar Ahmed, Qurban Ali Shah, Shulin Chen

“…The results highlight that AFB1 toxicity in birds exhibited low feed intake, reduction in weight gain, and a decrease in FCR while, bLF regulated these adverse effects. …”
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Ergothioneine attenuates psoriasis symptoms through modulation of M1/M2 macrophage polarisation via the NF-κB/JAK-STAT3 pathway by Ang Li, Yanjie Liu, Peiling Yu, Zhiyuan Zhang, Tengxiao Huang, Hang Li, Songzhi Wu, Xiaoyu Rong, Wensheng Liao, Hongqiang Wang, Yanzheng Gao

“…Furthermore, EGT was observed to reverse the LPS induced increase in the ratio of M1 to M2 macrophages. …”
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mindLAMPVis as a Co-Designed Clinician-Facing Data Visualization Portal to Integrate Clinical Observations From Digital Phenotyping in Schizophrenia: User-Centered Design Process a... by Karthik Sama, Jaya Sreevalsan-Nair, Soumya Choudhary, Srilakshmi Nagendra, Preethi V Reddy, Asher Cohen, Urvakhsh Meherwan Mehta, John Torous

“…The data were taken from the mindLAMP app and processed using multivariate analysis and dimensionality reduction to make it easy and manageable for clinicians to analyze. …”
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Mesenchymal stem cells improve ovarian function by suppressing fibrosis through CTGF/FAK signalling in systemic lupus erythematosus by Min Xu, Hui Yang, Lingyun Sun, Hongwei Chen, Yueyang Zhang, Haiwei Zhang, Yingyi Wu, Yirui Shi

“…Ovarian tissue samples were histologically evaluated for follicle count and fibrosis via H&amp;E and Masson’s trichrome staining. Quantitative reverse-transcriptase-PCR, western blot, immunofluorescence and immunohistochemistry were employed to evaluate inflammatory cytokines, fibrotic factors, hormone receptors and signalling proteins. …”
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