Genetic association study of TERT gene variants with chronic kidney disease susceptibility in the Chinese population by Yan Su, Yuan Feng, Xinran Lin, Chunyang Ma, Jiali Wei

“…Studies have demonstrated the significance of genetic risk factors in the progression of CKD. Telomerase reverse transcriptase (TERT) may be implicated in the development of CKD. …”
Get full text

Unveiling the complexities of lung transplantation in situs inversus by Chitaru Kurihara, Taisuke Kaiho, Ankit Bharat

“…Because of the significant size mismatch, nonanatomic lung volume reduction over the right middle and left upper lobes was necessary. …”
Get full text

Transcatheter edge‐to‐edge repair of atrial secondary mitral regurgitation positively influences atrial remodelling by Aniela Petrescu, Martin Geyer, Julian Andres Gelves Meza, Omar Hahad, Tobias Ruf, Valeria Maria deLuca, Lukas Hobohm, Theresa Gößler, Felix Kreidel, Philipp Lurz, Ralph Stephan vonBardeleben

“…Conclusions Transcatheter mitral valve repair by edge‐to‐edge therapy represents a safe and effective therapeutic option in symptomatic patients with atrial secondary mitral regurgitation and might have the potential to induce left atrial reverse remodelling.…”
Get full text

Enhancement of D1 dopaminergic responses in aged LRRK2 G2019S knock-in mice by Daniela Mercatelli, Alberto Brugnoli, Anna Di Maio, Federica Albanese, Derya R. Shimshek, Alessandro Usiello, Michele Morari

“…Intrastriatal SCH-233390 was also associated with a prolonged reduction of glutamate release in the substantia nigra reticulata in both genotypes. …”
Get full text

Electrocatalyst of PdNi Particles on Carbon Black for Hydrogen Oxidation Reaction in Alkaline Membrane Fuel Cell by Carolina Silva-Carrillo, Edgar Alonso Reynoso-Soto, Ivan Cruz-Reyes, Moisés Israel Salazar-Gastélum, Balter Trujillo-Navarrete, Sergio Pérez-Sicairos, José Roberto Flores-Hernández, Tatiana Romero-Castañón, Francisco Paraguay-Delgado, Rosa María Félix-Navarro

“…This work reports the synthesis of PdNi bimetallic particles and Pd on Carbon black (Vulcan XC-72) by reverse microemulsion and the chemical reduction of metallic complexes. …”
Get full text

Correlation between clinical data and cytokines parameters in patients with Granulomatosis with Poilyangiitis (Wegener Granulomatosis) by I. A. Lopatina, S. V. Moiseev, P. I. Novikov, L. I. Russu, E. I. Isaeva, M. V. Mezentseva

“…Total negative correlations were between ear disease and IL-12 gene expression; glomerular filtration rate reduction more than 50% and serum IFN-α ( r =-1,00). …”
Get full text

Unveiling Therapeutic Potential of Yoga Mitigating Oxidative Stress and Mitochondrial Dysfunction in PCOS: A Randomized Controlled Trial by Deepika Kumari, Manoj Kumar, Ashish Datt Upadhyay, Neena Malhotra, Reeta Mahey, Vatsala Dadhwal, Tushar Sehgal, Richa Mishra, Rima Dada

“…In addition, the post-yoga group shows a reduction in, lipid peroxidation, inflammatory, OS markers, and an improvement in telomere length. …”
Get full text

SERCA-mediated endoplasmic reticulum stress facilitates hematopoietic stem cell mobilization by Lijun Li, Danhua Xu, Xinxin Huang

“…This inhibition led to a reduction in CXCR4 expression on the surface of HSCs, facilitating their migration from the bone marrow into peripheral circulation. …”
Get full text

Inhibition of LINC00707/miR‐223‐3p/FKBP5 axis has a protective effect on diabetic kidney disease by Hongzhen Ye, Yiting Chen, Hong Xia, Lingbo Lv, Lijun Gao

“…Significantly, the inhibition of miR‐223‐3p was found to reverse these observed effects. Further investigation revealed that miR‐223‐3p directly targets FK506‐binding protein 5 (FKBP5). …”
Get full text

Synergistic amelioration of obesity in high‐fat diet–fed mice by Bifidobacterium longum and green banana powder through targeting multiple pathways by Yi‐Yao Lu, Zhi Jia, Meng‐Yue Zhang, Juan Cheng, Ze‐Xu Yu, Ye Li, Yi‐Xuan Zhang, Xin Wu

“…Overall, this study demonstrates that BL combined with GBP can effectively alleviate dietary obesity, highlighting its potential as a non‐pharmacological intervention for weight reduction.…”
Get full text

Research on the Maximum Regenerative Energy Commutation Control Strategy of a Dual-Mode Synergistic Energy Recovery Pump-Controlled Grinder by Bo Yu, Gexin Chen, Keyi Liu, Guishan Yan, Yaou Zhang, Yinping Liu

“…The results show that the proposed strategy effectively maximizes energy capture; experiments indicate a 14.3% increase in energy recovery efficiency and a 25% reduction in commutation time compared to a fixed timing approach. …”
Get full text

Electroacupuncture Improves Ovarian Function in Rats With Tripterygium Glycoside-Induced Diminished Ovarian Reserve by Promoting the Polarization of M2 Macrophages and Inhibiting I... by Jia Luo, Yantong Qin, Yaoyao Zhu, Yaoli Yin, Meihong Shen

“…EA intervention reduced the oestrous cycle disorder rate in the rats compared with that in the DOR group, leading to an increase in growing follicles, a reduction in atretic follicles (AFs) and an enhancement of both the capillary (Cap) network and corpus luteum (CL) structure. …”
Get full text

Serum iron levels and the risk of Parkinson disease: a Mendelian randomization study. by Irene Pichler, Fabiola Del Greco M, Martin Gögele, Christina M Lill, Lars Bertram, Chuong B Do, Nicholas Eriksson, Tatiana Foroud, Richard H Myers, PD GWAS Consortium, Michael Nalls, Margaux F Keller, International Parkinson's Disease Genomics Consortium, Wellcome Trust Case Control Consortium 2, Beben Benyamin, John B Whitfield, Genetics of Iron Status Consortium, Peter P Pramstaller, Andrew A Hicks, John R Thompson, Cosetta Minelli

“…Epidemiological studies suffer from problems of confounding and reverse causation, and mendelian randomization (MR) represents an alternative approach to provide unconfounded estimates of the effects of biomarkers on disease. …”
Get full text

DInSAR Analysis of Ground Deformation Induced by the 2023 Al Haouz Earthquake, Morocco by A. Habib, I. Berrada, A. El Adnani, Y. A. Laaziz, A. Fadili, A. Lagnaoui, A. Lagnaoui, A. Najih, T. Y. Arrad

“…Additionally, these results have important implications for seismic hazard assessment and disaster risk reduction in Morocco's tectonically active regions.…”
Get full text

Establishment and optimization of a tobacco rattle virus -based virus-induced gene Silencing in Atriplex canescens by Shan Feng, Jin-Da Chen, Ai-Ke Bao

“…Systemic photobleaching phenotypes appeared in newly emerged leaves at about 15 days post-inoculation, accompanied by a 40–80% reduction in AcPDS transcript abundance, as confirmed by qRT-PCR. …”
Get full text

Exosomal LncRNA SCAMP1-AS1 enhances osteosarcoma malignancy by regulating the LKB1-AMPK signaling pathway by Yanxia Li, Xiuqi Zou, Xiaomin Feng, Jing Xia, Zhifeng Wu, Haili Ma

“…The results revealed high SCAMP1-AS1 expression in OS, and its silencing in OS cells led to a reduction in cell proliferation, migration, and invasion. …”
Get full text

HDL Improves Cholesterol and Glucose Homeostasis and Reduces Atherosclerosis in Diabetes-Associated Atherosclerosis by Belinda A. Di Bartolo, Siân P. Cartland, Scott Genner, Pradeep Manuneedhi Cholan, Melissa Vellozzi, Kerry-Anne Rye, Mary M. Kavurma

“…Immunohistological analysis of pancreata revealed increased insulin expression/production and a reduction in macrophage infiltration in mice with TRAIL deletion. …”
Get full text

Induced variation in BRASSINOSTEROID INSENSITIVE 1 (BRI1) confers a compact wheat architecture by Manpartik S. Gill, Andrew L. Phillips, Danuše Tarkowská, John Addy, Patrycja Sokolowska, M. John Foulkes, Stephen Pearce, Stephen G. Thomas, Peter Hedden

“…The less severe mutant had a 56% reduction in FLA and was 35% shorter than the wild type, although seed set, seed area and grain weights were also reduced. …”
Get full text

Melatonin alleviates ferroptosis triggered by cadmium via regulating ferritinophagy and iron metabolism in spermatogonia by Didi Jia, Wei Huang, Qizi Yin, Han Wang, Ziyue Wang, Mingming Zhang, Wenjing Gong, Rong Wang, Yan Zhu, Yanli Ji

“…Exposure to Cd resulted in a reduction of the mitochondrial membrane potential of the cells. …”
Get full text

Enhancing the color and stress tolerance of cherry shrimp (Neocaridina davidi var. red) using astaxanthin and Bidens Pilosa. by Wei-Wei Hou, Yu-Tzi Chang, Wen-Chin Yang, Hong-Yi Gong, Yen-Ju Pan, Te-Hua Hsu, Chang-Wen Huang

“…Color parameters were assessed using CIELAB color space, and differential gene expression related to color and stress was analyzed using reverse transcription quantitative polymerase chain reaction (RT-qPCR) to understand the gene regulatory mechanisms affecting color expression and stability. …”
Get full text