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EMT induction in normal breast epithelial cells by COX2-expressing fibroblasts
Published 2025-05-01“…Together, our findings support a model in which PGE2–EP4 signaling contributes to EMT induction, potentially involving SNAI1 regulation, with implications for targeting stromal-epithelial interactions in breast cancer. …”
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Anti‐Osteoporosis Treatment Alleviates Osteoarthritis Symptoms and Partially Reverses Disease Progression
Published 2025-08-01“…In animal studies, OP was induced in rats by ovariectomy, followed by OA induction via anterior cruciate ligament sectioning and meniscectomy. …”
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Posttraining Epinephrine Reverses Memory Deficits Produced by Traumatic Brain Injury in Rats
Published 2016-01-01“…These data indicate that posttraining epinephrine and, to a lesser extent, vehicle injection reduce memory deficits associated with TBI, probably through induction of a low-to-moderate emotional arousal.…”
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HIV Tat as a latency reversing agent: turning the tables on viral persistence
Published 2025-04-01“…The ‘shock and kill’ approach to an HIV cure involves the use of latency reversing agents (LRAs) to reactivate latent HIV, with the aim to induce death of infected cells through virus induced cytolysis or immune mediated clearance. …”
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Identification of pharmacological inducers of a reversible hypometabolic state for whole organ preservation
Published 2024-09-01“…Drugs that induce reversible slowing of metabolic and physiological processes would have great value for organ preservation, especially for organs with high susceptibility to hypoxia-reperfusion injury, such as the heart. …”
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Numerical Simulation Analysis on a Composite Edge Terminal Reverse Blocking IGBT
Published 2022-09-01“…Insulated gate bipolar transistor (IGBT) is usually used in combination with power diode in power electric circuit because it has no reverse blocking ability. In order to reduce cost and parasitic inductance, the freewheeling diode and IGBT are integrated by process method, and a reverse blocking insulated gate bipolar transistor (RB-IGBT) is thus proposed. …”
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Hemopexin and HO-1 induction during acute colitis in mice is dependent on interleukin-22
Published 2025-07-01“…Wild-type (Wt) and Il22ra1-/- mice were used to evaluate the effects of exogenous hemopexin and hemin treatments on colitis severity.ResultsIL-22 signaling was crucial for the induction of hemopexin in the colon, as Il22ra1-/- mice exhibited limited hemopexin induction and more severe colitis, which could be reversed by recombinant hemopexin administration. …”
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The liver-selective thyromimetic T-0681 influences reverse cholesterol transport and atherosclerosis development in mice.
Published 2010-01-01“…<h4>Background</h4>Liver-selective thyromimetics have been reported to efficiently reduce plasma cholesterol through the hepatic induction of both, the low-density lipoprotein receptor (LDLr) and the high-density lipoprotein (HDL) receptor; the scavenger receptor class B type I (SR-BI). …”
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Calpain inhibition in a transgenic model of calpastatin overexpression facilitates reversal of myocardial hypertrophy
Published 2025-06-01“…However, CAST OE mice demonstrated a complete reversal of hypertrophy when angiotensin‐II was removed, whereas hypertrophy persisted in non‐induced controls (CAST OE 5.0 ± 0.5; non‐induced 7.0 ± 0.4; P < 0.0001). …”
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Implementation of regenerative braking on the AC locomotive with a mono phase reversible voltage converter
Published 2022-03-01“…The article consided theoretically possible options for the operation of monophase reversible voltage converters during regenerative braking, in which: 1) the reactive component of the electric locomotive current had a capacitive nature, and the operating current of the electric locomotive was ahead of its reactive component; 2) the reactive component of the electric locomotive current had an inductive nature, and the current of the electric locomotive was ahead of its active component. …”
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Critical role of the virus-encoded microRNA-155 ortholog in the induction of Marek's disease lymphomas.
Published 2011-02-01“…Using viruses modified by reverse genetics of the infectious BAC clone of the oncogenic RB-1B strain of MDV, we show that the deletion of the six-miRNA cluster 1 from the viral genome abolished the oncogenicity of the virus. …”
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Effects of solamargine in hepatic metastasis of colorectal cancer: induction of ferroptosis and elimination of cancer stem cells
Published 2025-07-01“…Methods CCK-8 assay, colony-formation assay, transwell assay, flow cytometry, tumoursphere formation assay, reverse-transcription quantitative PCR (RT-qPCR), Western blotting, transcriptomic sequencing and ferroptosis analysis were performed to reveal the efficacy and the underlying mechanism of SM in CRC cell lines. …”
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SARS-CoV-2-Triggered Hemophagocytic Lymphohistiocytosis with Complications of Posterior Reversible Encephalopathy Syndrome
Published 2024-01-01“…In this article, we describe a novel case of SARS-CoV-2-associated-hemophagocytic lymphohistiocytosis (HLH) complicated by posterior reversible encephalopathy syndrome (PRES). Initially diagnosed with multisystem inflammatory response in children (MIS-C), the patient received a large corticosteroid dose days before the onset of neurological symptoms. …”
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Isolated cerebellar involvement in posterior reversible encephalopathy syndrome in a child with acute lymphoblastic leukemia
Published 2011-01-01“…He improved within few hours and reversibility of the lesions was documented on magnetic resonance imaging after 2 weeks. …”
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Possible Role of N-Methyl-D-Aspartate Glutamate Receptors in The Induction of Acrosome Reaction in Human Sperm
Published 2024-12-01“…The application of MK-801+ L-glutamate could significantly(P=0.047) reverse the effect of L-glutamate on cytosolic Ca2+ levels compared to the L-glutamate group.Conclusion: The results of the present study showed that NMDA glutamate receptors play an essential role not only inthe increase of cytosolic Ca2+ levels but also in the induction of the acrosome reaction in human sperm.…”
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An induction machine‐based drive system and supervisory control for application to smart water‐pumped storage and networks
Published 2024-12-01“…Abstract The authors present an effective induction machine (IM) drive system and intelligent supervisory control for application to smart water‐pumped storage and networks. …”
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New Surgical Technique to Induce Reversible Liver Fibrosis by Surgical Closure of Major Duodenal Orifice in Dogs
Published 2021-12-01“…In conclusion, surgical induction of reversible liver fibrosis in dogs was an easy technique by surgical closure of major duodenal papilla and the results were confirmed by the clinical, ultrasonographical, laboratory and histological examination.…”
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Inducible and reversible Clock gene expression in brain using the tTA system for the study of circadian behavior.
Published 2007-02-01“…Importantly, low, but not high, doses of Dox were completely reversible and led to a rapid reactivation of the tetO transgenes. …”
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