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241
Bisphenol A suppresses colon epithelial cell responses via G0/G1-phase arrest, MAPK and PI3K/AKT pathway modulation, and MMP-2/9 Inhibition by upregulating p21WAF1
Published 2025-07-01“…This BPA-induced regulation of colonic epithelial cell proliferation, migration, invasion, and MAPK/AKT pathway was reversed by silencing p21WAF1 with siRNA. Collectively, our data indicate that BPA inhibits the proliferation and mobility of human colonic epithelial cells via p21WAF1 induction. …”
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242
Transcriptomic evidence for atopic dermatitis as a systemic disease in NC/Nga mice
Published 2024-11-01“…Conclusions Using NC/Nga mice with AD-like symptoms, we compared the transcriptomes of the skeletal muscle (a tissue that is relatively distant from the skin) with those of the skin (the lesion induction site) before and after disease induction, after which Hc was administered. …”
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243
Cardiac Arrest Induces Ischemic Long-Term Potentiation of Hippocampal CA1 Neurons That Occludes Physiological Long-Term Potentiation
Published 2018-01-01“…These results are consistent with a reversal, or depotentiation, of iLTP. Further, depotentiation with LFS partially restored induction of pLTP with theta burst stimulation. …”
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244
The Modulatory Role of Heme Oxygenase on Subpressor Angiotensin II-Induced Hypertension and Renal Injury
Published 2012-01-01“…We next examined whether additional chronic or late induction of SP-AngII-induced HO (using cobalt protoporphyrin; CoPP), prevents or ameliorates renal damage. …”
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245
Comparison of Intramuscular Ketamine–Medetomidine, Ketamine–Dexmedetomidine and Ketamine–Xylazine for Immobilization of Captive Rhesus Macaques (<i>Macaca mulatta</i>)
Published 2025-01-01“…Induction and recovery times were longer for KX than KD or KM (<i>p</i> < 0.05) but did not differ significantly between KD and KM (<i>p</i> > 0.05). …”
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246
Pseudohypoxic stabilization of HIF1α via cyclophilin D suppression promotes melanoma metastasis
Published 2025-07-01“…Overexpression of CypD reversed the pseudohypoxic state and potently inhibited melanoma metastasis. …”
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247
The nitrergic mechanism of geraniol in PTZ-induced seizures
Published 2025-12-01“…All drugs were administered intraperitoneally 30 min before seizure induction by intravenous infusion of PTZ. The last group served as the control for biochemical and molecular tests (no seizure induction). …”
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248
Knockdown of IER3 Promotes Osteogenic Differentiation of Human Mesenchymal Stem Cells
Published 2025-04-01“…Furthermore, inhibition of the MAPK/ERK signaling pathway reversed the enhanced osteogenic differentiation observed following IER3 knockdown. …”
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249
Effect of Remimazolam versus Propofol on Hemodynamics in Elderly Hypertensive Patients Undergoing Gastroenteroscopy: A Multicenter, Randomized Controlled Clinical Trial
Published 2025-07-01“…Flumazenil or placebo was administered for reversal. Hemodynamics were monitored via Continuous Non-Invasive Arterial Pressure (CNAP). …”
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250
Saisir l’« Europe » à la lueur du discours officiel de l’UE : l’analyse de données au service d’une régionalisation critique de l’Europe
Published 2020-11-01“…By using a combination of inductive and deductive methods from data analysis, this article will provide an opportunity to propose a critical and fuzzy regionalization of this political project. …”
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251
Gender Dysphoria in Adolescents
Published 2022-09-01“…Therefore, the individual should be evaluated with the DSM-V diagnostic criteria, and after obtaining the necessary medical consents, puberty should be suppressed with GnRH agonists, which is a reversible treatment, and the next step, puberty induction, should be applied in patients with medical indications. …”
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252
The effects of the urotensin-II receptor antagonist palosuran treatment on the corpora cavernosa of streptozotocin-induced diabetic rats
Published 2025-01-01“…Although induction of diabetes did not change U-II expression in CC significantly, palosuran treatment reduced U-II expression in diabetic CC. …”
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253
Protein kinase CK2 sustains de novo fatty acid synthesis by regulating the expression of SCD-1 in human renal cancer cells
Published 2024-12-01“…Both effects could be reversed by supplementing the growth medium with oleic acid indicating that these effects are specifically caused by reduced expression of SCD-1. …”
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254
Role of Translationally Controlled Tumor Protein in Cancer Progression
Published 2012-01-01“…Previous studies revealed that TCTP is implicated in many biological processes, including cell growth, tumor reversion, and induction of pluripotent stem cell. …”
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255
METTL3-mediated m6A modification regulates D-galactose-induced skin fibroblast senescence through miR-208a-5p
Published 2025-06-01“…Critically, senescent phenotypes induced by METTL3 knockdown or miR-208a-5p mimicry were reversed by pharmacological mitophagy induction (GSK), confirming mitochondrial homeostasis as the pathway's functional nexus.DiscussionThese results establish an m6A-dependent METTL3/miR-208a-5p/OPA1 axis that regulates mitophagy and skin aging. …”
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256
M.R.H. A New Era in Magnetic Head Design
Published 1986-09-01“…To retrieve the information (i.e. playback the recorded signals) the prerecorded tape is swiped across the poles of the inductive head. In this case the reverse of the write cycle occurs i.e. the magnetic field from the tape influence the former in such a manner as to cause a current flow through the coil having the same form as the recorded signal. …”
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257
High-step-up quadratic DC–DC converter based on switched capacitor and coupled inductor techniques
Published 2025-03-01“…The diode-capacitor clamp circuit is utilized to reduce the negative effects caused by the leakage inductance and recover the energy stored in it. The performance of the proposed converter is analyzed in the continuous and discontinuous conduction modes. …”
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258
Study on a Trans-Inverse High Gain SEPIC-Based DC-DC Converter With ZCS Characteristics for Photovoltaic Applications
Published 2025-01-01“…Furthermore, a passive voltage clamp is employed to reduce the voltage stress on the switch and recover the energy stored in the leakage inductance of the coupled inductor. Hence, a switch with low RDS-ON could be used. …”
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259
Staurosporine and extracellular matrix proteins mediate the conversion of small cell lung carcinoma cells into a neuron-like phenotype.
Published 2014-01-01“…Here, we show that four out of five SCLC cell lines reversibly develop a neuron-like phenotype on extracellular matrix constituents such as fibronectin, laminin or thrombospondin upon staurosporine treatment in an RGD/integrin-mediated manner. …”
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260
Generation and evaluation of an IPTG-regulated version of Vav-gene promoter for mouse transgenesis.
Published 2011-03-01“…However, reporter expression was not uniform and the lacO elements introduced into the Vav-gene promoter only conferred limited repression and reversion of lacI-mediated gene silencing after administration of IPTG. …”
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