Estrogen and progesterone attenuate CD4-positive immune cell traffic to the penumbra region of rat’s ischemic stroke brain by Aboutaleb Tamtaji, Sayyed Alireza Talaei, Homayoun Naderian, Mohammad Ali Atlasi, Nasim Alipour, Abolfazl Azami-Tameh

“…Moreover, E/P treatment could reverse these effects of stroke.…”
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SREBF1 mediates immunoparalysis of dendritic cells in sepsis by regulating lipid metabolism and endoplasmic reticulum stress by Yaolu Zhang, Fangfang Wu, Yan Li, Jiaxin Liu, Liuyan Zhu, Min Zhang, Zhongqiu Lu

“…Mechanistically, SREBF1 activation enhanced lipid biosynthesis in DCs, which triggered endoplasmic reticulum (ER) stress, as evidenced by increased PERK phosphorylation, eIF2α activation, and subsequent ATF4/CHOP induction. SREBF1 silencing attenuated the lipid-induced ER stress and restored DC function, whereas tunicamycin treatment partially reversed these protective effects. …”
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Improving antioxidant scavenging effect of fruit peel waste extracts and their applicability in biodiesel stability enhancement by Usman Bello, Nurul Aini Amran, Muhammad Syafiq Hazwan Ruslan

“…Finally, the peel extracts demonstrate an improved antioxidative performance by prolonging the biodiesel’s induction period of the extracts-blended samples as obtained from Rancimat analysis.…”
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Design and Experimentation of a Height-Adjustable Management Platform for Pineapple Fields by Sili Zhou, Fengguang He, Ganran Deng, Ye Dai, Xilin Wang, Bin Yan, Pinlan Chen, Zehua Liu, Bin Li, Dexuan Pan

“…Field validation demonstrated operational velocities of 0.16–1.77 m/s (forward) and 0.11–0.28 m/s (reverse), with a maximum gradability of 20°. The platform exhibited multifunctional capabilities including weeding, spraying, fertilization, flower induction, harvesting, and transportation, demonstrating its potential to fulfill the operational requirements for pineapple field management. …”
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Morin Mitigates Methamphetamine-Induced Neurotoxicity: Effects on Motor and Cognitive Function by Anyanwu GE, Umeano AV, Ojiakor VO, Katchy AU, Anyanwu CN, Fakorede S

“…Following METH induction, Morin, a natural flavonoid with antioxidant properties, was administered to rats. …”
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Vitamin C stimulates RNA expression of human gingival fibroblasts proliferation and adhesion in cigarette smokers: An in vitro study by Ruaa Alyami, Fahad Ali Alshehri, Reham Al Jasser, Sameerah Shaheen, Amer Mahmood, Mona Ahmed Elsafadi

“…RNA expression analysis using quantitative reverse transcriptase-polymerase chain reaction was performed to analyze the adhesion, proliferation, and extracellular matrix expression. …”
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Effects of the combination of melatonin and N-acetylcysteine on the inflammatory response in a rat model of cerebral ischemia by Pouria Soleimani, Saied Nekoonam, Fariba Zafari, Fatemeh Sabbaghziarani

“…The rats were treated by administering NAC (50 mg/kg), melatonin (5 mg/kg) and the combination of NAC + melatonin by intraperitoneal injection after ischemia induction. The animals were assessed for sensory-motor activity at 24 and 72 h. …”
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Successfully treatment of PLZF-RARα positive acute promyelocytic leukemia by Venetoclax combining with decitabine: a case report and literature review by Ziwei Zhou, Erling Chen, Jiqian Jiang, Lei Xue, Lijun Zhu, Xing Hu, Yingqiao Zhu, Changcheng Zheng, Juan Tong

“…Knowledge of PLZF-RARα (+) APL treatment remains limited understood.Case report: We presented a case of variant APL in a 47-year-old female, who was PLZF-RARα positive detected by reverse transcription polymerase chain reaction (RT–PCR). …”
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Loading diltiazem onto surface-modified nanostructured lipid carriers to evaluate its apoptotic, cytotoxic, and inflammatory effects on human breast cancer cells by Vahid Pouresmaeil, Marwa Mawlood Salman Al-zand, Aida Pouresmaeil, Seyedeh Samira Saghravanian, Masoud Homayouni Tabrizi

“…Flow cytometry was used for cell cycle analysis, and reverse transcription polymerase chain reaction (RT-PCR) was performed to assess the induction of apoptosis. …”
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Blocking variant surface glycoprotein synthesis in Trypanosoma brucei triggers a general arrest in translation initiation. by Terry K Smith, Nadina Vasileva, Eva Gluenz, Stephen Terry, Neil Portman, Susanne Kramer, Mark Carrington, Shulamit Michaeli, Keith Gull, Gloria Rudenko

“…Blocking VSG synthesis by the induction of VSG RNAi triggers an unusually precise precytokinesis cell-cycle arrest.…”
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Epigenetic regulation of the respiratory chain by a mitochondrial distress-related redox signal by Marius W. Baeken, Marius W. Baeken, Ankush Borlepawar, Philipp Kötzner, Holger Richly, Christian Behl, Bernd Moosmann, Parvana Hajieva, Parvana Hajieva

“…Analysis of MPTP-treated mice recapitulated the PHT-reversible induction of histone acetylation and DNMT3B suppression in vivo. …”
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Limonene as a potential cardioprotective agent: mechanistic intuitions into antioxidant and anti-apoptotic properties in isoproterenol-induced ischemia in rats by Sepehr Ebrahimi-Dehkordi, Zahra Lorigooini, Elham Bijad, Zahra Rezaei, Fariba Hooshmand, Hossein Amini-Khoei

“…ISO-I is associated with a decrease in Bcl-2 (0.880±0.118 versus 1.74±0.178) and an increase in BAX (2.75±0.124 versus 1.08±0.0938) gene expression in comparison to the control group (P<0.001 for both genes). LIM could reverse the aforementioned heart damage-related biomarkers in the serum and heart samples. …”
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Electroacupuncture Alleviates Neuropathic Pain and Negative Emotion in Mice by Regulating Gut Microbiota by Feng C, Pan H, Zhang Y, Ye Z, Zhou Y, Zou H, Wang K

“…However, EA could partially reverse changes in the diversity of gut microbiota. …”
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Chronic, Low-Dose Methamphetamine Reveals Sexual Dimorphism of Memory Performance, Histopathology, and Gene Expression Affected by HIV-1 Tat Protein in a Transgenic Model of NeuroH... by Indira S. Harahap-Carrillo, Dominic Fok, Frances Wong, Gabriel Malik, Ricky Maung, Xinru Qiu, Daniel Ojeda-Juárez, Victoria E. Thaney, Ana B. Sanchez, Adam Godzik, Amanda J. Roberts, Marcus Kaul

“…Seven months after transient Tat induction and five months after METH exposure ended, we detected behavioral changes in the Barnes maze (BM) spatial memory task in the Tat and METH groups but not the combined Tat + METH group. …”
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Impact of MiRNAs on Wnt-related gene activity in breast cancer by Tomasz Sirek, Agata Sirek, Nikola Zmarzły, Marcin Opławski, Katarzyna Król-Jatręga, Dariusz Boroń, Michał Chalcarz, Piotr Ossowski, Konrad Dziobek, Damian Strojny, Joanna Szymańska, Julia Gajdeczka, Przemysław Borawski, Kacper Boroń, Beniamin Oskar Grabarek

“…Its disruption may promote the induction of breast cancer and its further development. …”
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Ursolic acid inhibiting excessive reticulophagic flux contributes to alleviate ochratoxin A-induced endoplasmic reticulum stress- and mitochondrial-mediated apoptosis by Huiqiong Deng, Wenying Chen, Lingyun Han, Boyang Zhang, Xun Luo, Song Yao, Hongwei Wang, Yao Zhou, Shuangchao Liu, Xiao Li Shen

“…Additionally, excessive induction of endoplasmic reticulum (ER)-phagy exacerbates OTA-induced apoptosis. …”
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Molecular mechanisms of anticancer activity of deoxyelephantopin in cancer cells by Farha Arakkaveettil Kabeer, Dhanya Sethumadhavan Rajalekshmi, Mangalam Sivasankaran Nair, Remani Prathapan

“…Moreover, apoptosis induction was associated with mitochondrial permeability and endoplasmic reticulum stress. …”
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Discovery of drug transporter inhibitors tied to long noncoding RNA in resistant cancer cells; a computational model -in silico- study by Mohanad Diab, Amel Hamdi, Feras Al-Obeidat, Wael Hafez, Wael Hafez, Ivan Cherrez-Ojeda, Ivan Cherrez-Ojeda, Muneir Gador, Gowhar Rashid, Sana F. Elkhazin, Mahmad Anwar Ibrahim, Tarek Farag Ismail, Samar Sami Alkafaas

“…These inhibitors can reverse multi-drug resistance and induce the sensitivity of resistant cancer cells toward chemotherapy based on in silico molecular docking. …”
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In vitro antibacterial and antibiofilm activities of isobavachalcone against Enterococcus faecalis clinical isolates from China by Lili Ouyang, Zhicao Xu, Yuanyuan Tang, Duoyun Li, Zhijian Yu, Zewen Wen, Haigang Zhang, Chaoqin Zhang

“…Abstract Background The pharmacological activities of the natural product isobavachalcone, such as antimicrobial activity, reverse transcriptase blockade, and antioxidant property have been extensively reported. …”
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Safe Use of Butorphanol–Azaperone–Medetomidine to Immobilize Free‐Ranging White‐tailed Deer by Joseph R. McDermott, Wendy Leuenberger, Caleb A. Haymes, Garrett B. Clevinger, Jonathan K. Trudeau, Tim C. Carter, John T. Hast, Gabriel S. W. Jenkins, Will E. Bowling, John J. Cox

“…Times to first signs of induction and the induction period were longer for adults than for juveniles, while times to the first sign of reversal, lifting head, and standing were longer for juveniles than adults. …”
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