Suggested Topics within your search.
Suggested Topics within your search.
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821
Exercise-Induced Cognitive Improvement Is Associated with Sodium Channel-Mediated Excitability in APP/PS1 Mice
Published 2020-01-01“…Blocking the overexcitation of the neural network may be a promising new strategy to prevent, halt, and even reverse this condition. Physical exercise has been shown to be an effective cognitive enhancer that reduces the risk of AD in elderly individuals, but the underlying mechanisms are far from being fully understood. …”
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822
Gut cannabinoid receptor 1 regulates alcohol binge-induced intestinal permeability
Published 2025-02-01“…Background Endocannabinoids acting via cannabinoid receptor 1 (CB1R) can elicit increased intestinal permeability (a condition also called ‘leaky gut’). Alcohol binge can adversely affect digestive functions, including intestinal permeability; however, the underlying mechanisms remain incompletely understood. …”
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823
The main approaches to the formation of competence in the field of diagnostics of circuits based on FPGA
Published 2018-01-01“…The authors formulated conditions sufficient for the generation of the diagnostic sequence for the detection of constant errors in the combinational circuits on the base of the analytical form. …”
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824
Serum/glucose starvation enhances binding of miR-4745-5p and miR-6798-5p to HNRNPA1 mRNA 3ʹUTR: A novel method to identify miRNAs binding to mRNA 3ʹUTR using λN peptide-boxB sequen...
Published 2025-04-01“…Reporter assays, anti-miRNA and mutated miRNA-based assays, photoactivatable ribonucleoside-enhanced crosslinking and immunoprecipitation/reverse transcribed-quantitative polymerase chain reaction, and transient overexpression of miRNAs showed that miR-4745-5p and miR-6798-5p suppress hnRNP A1 protein levels via enhancement of binding to HNRNPA1 mRNA 3ʹUTR under serum/glucose-starved condition. miR-4745-5p and miR-6798-5p overexpression significantly decreased growth rates, which was rescued by co-transfection with anti-miRNA for miR-4745-5p and miR-6798-5p. …”
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825
GABAB receptor activation contributes to post-surgery cognitive impairments in mice by inducing hippocampal BDNF hypermethylation
Published 2025-12-01“…Our findings suggest that inhibition of GABAB receptor activation to reverse BDNF hypermethylation may represent a potential therapeutic strategy for alleviating PND.…”
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826
Investigation of Transitional Processes and Sliding Motions in Quasi-Relay Follow-Up Systems
Published 2010-12-01“…The paper demonstrates that it is possible significantly to simplify technical realization of sliding modes in quasi-relay follow-up systems having non-reversive direct tract supplemented by a reverse channel. …”
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827
An Experimental Study of the Unsteady Aerodynamics of a Static DU91‐W2‐150 Airfoil at Large Angles of Attack
Published 2025-03-01“…This is owing to separation occurring at the aerodynamic leading edge (geometric trailing edge) in reverse flow. In terms of vortex shedding frequency, the study found a nearly constant normalized Strouhal number (St) of 0.16 across various Re and AoA values in fully separated regions, indicating a consistent pattern under these conditions. …”
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828
弧齿锥齿轮齿面接触应力分析
Published 2012-01-01“…When a spiral bevel gear is working its tooth contact stress has direct effect on its service life and safety.Using reverse engineering technology of CATIA,the 3D model of spiral bevel gear is built.And using the seamless connection interface of CATIA and ABAQUS,the gear model is imported into finite element analysis software ABAQUS.In the ABAQUS Environment set the material of the gears and then contact stress analysis of the spiral bevel gear is completed under the conditions to get the most dangerous place for local stress and strain.…”
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829
Pharmacological and physiological activation of TGR5 in the NTS lowers food intake by enhancing leptin-STAT3 signaling
Published 2025-05-01“…Our findings highlight the potential of targeting TGR5 to reverse leptin resistance in the NTS.…”
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830
Diagnosing a hematopoietic malignancy during shoulder arthroplasty: A case report
Published 2022-01-01“…The patient underwent reverse shoulder arthroplasty. During surgery, a 2.5 × 1.5 × 1 cm sized lymph node was observed near the left cephalic vein. …”
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831
Inversion of electric field component Ex in the SOTEM method based on the improved particle swarm optimization algorithm
Published 2025-04-01“…To address this challenge, this study proposed an improved particle swarm optimization (PSO) algorithm that integrates the center of gravity reverse learning strategy. MethodsBased on the center of gravity reverse learning strategy, the improved PSO algorithm can dynamically adjust learning factors and the value of the adaptive inertia weight, thus improving the global search capability and convergence efficiency effectively. …”
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832
Rheology study of the starch gelatinization to understand the hematite depression process
Published 2024-11-01“…The main aim was to highlight how starch gel preparation can influence hematite depression in cationic reverse flotation. The steady and dynamic shear rheological measurements plus optical micrographs were assessed for the starch gel gelatinization process for different SNMR conditions. …”
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833
Perturb, Attend, Detect, and Localize (PADL): Robust Proactive Image Defense
Published 2025-01-01“…PADL’s key objective is to provide a secure and adaptive protection mechanism that ensures the authenticity of images by detecting and localizing manipulations, drastically reducing the possibility of reverse engineering. The method consists of two key components: an encoder, which conditions a learnable perturbation on the input image to ensure uniqueness and robustness against attacks, and a decoder, which extracts the perturbation and leverages it for manipulation detection and localization. …”
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834
Optimization of glycine and thiotriazoline compound analysis by high-performance liquid chromatography
Published 2020-08-01“…Іt was found that the determination of the active substances should be carried in the conditions of pair chromatography on the reverse phase when using tetrabutylammonium eluent with the simultaneous use of acid buffer – 0.05 % solution of trifluoroacetic acid…”
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835
THE INDUSTRIAL ORGANIZATION MANAGEMENT IN TERMS OF THE DIGITAL ECONOMY
Published 2018-11-01“…The overview of key production and information technologies, providing a competitive advantage for an industrial or-ganization in the field of digitalization, has given. The necessary conditions for the ef-fective interaction of service and production units within the production company on the base of the Internet of things, additive production and reverse engineering have spec-ified. …”
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836
Astaxanthin ameliorates benzalkonium chloride–induced dry eye disease through suppressing inflammation and oxidative stress via Keap1‐Nrf2/HO‐1 signaling pathways
Published 2025-06-01“…In vivo experiments demonstrated an improved overall condition in AST‐administered mice in contrast to the control group. …”
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837
A mechanistic systems biology model of brain microvascular endothelial cell signaling reveals dynamic pathway-based therapeutic targets for brain ischemia
Published 2024-12-01“…Through high-throughput model sensitivity analyses and virtual target perturbations in model-based single cells, our model predicted that targeting succinate could effectively reverse the detrimental cell phenotype of BMECs under oxygen and glucose deprivation/reoxygenation, a condition that mimics stroke pathogenesis, and we experimentally validated the utility of this new target in terms of regulating inflammatory factor production, free radical generation and tight junction protection in vitro and in vivo. …”
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838
Nonspecific craniovertebral spondylitis: features of surgical tactics
Published 2024-12-01“…In the rest patients, the sequence of surgical treatment had the reverse order. In 6 cases, combined operations were performed simultaneously, and in one case — with an interval of 7 days. …”
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839
Defective autophagy is a key feature of cerebral cavernous malformations
Published 2015-09-01“…Cerebral cavernous malformation is a genetic disease that may arise sporadically or be inherited as an autosomal dominant condition with incomplete penetrance and variable expressivity. …”
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840
ODONTALGIA IN MAXILLOFACIAL REGION
Published 2021-06-01“…More often the pain radiates to the frontal region, orbit, or ear. The reverse development of the syndrome may also occur: pain sensations begin in the face and spread to the cervico-occipital region. …”
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