Involvement of Histone Lysine Methylation in p21 Gene Expression in Rat Kidney In Vivo and Rat Mesangial Cells In Vitro under Diabetic Conditions by Xiangjun Li, Chaoyuan Li, Xiaoxia Li, Peihe Cui, Qifeng Li, Qiaoyan Guo, Hongbo Han, Shujun Liu, Guangdong Sun

“…HG-treated RMCs exhibited increased p21 mRNA, H3K4me level, SET7/9 recruitment, and inverse H3K9me, which were reversed by TGF-β1 antibody. These data uncovered key roles of H3Kme and SET7/9 responsible for p21 gene expression in vivo and in vitro under diabetic conditions and confirmed preventive effect of TGF-β1 antibody on DN.…”
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Peculiairities of mRNA TLR-2, TLR-4 expression of the oral cavity epithelium in children under conditions of chronic catarrhal gingivitis and diabetes mellitus by А. V. Kotelban, О. І. Godovanets, G. D. Koval, О. М. Kamyshnyi

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Numerical examination of the chemically reactive MHD flow of hybrid nanofluids over a two-dimensional stretching surface with the Cattaneo–Christov model and slip conditions by Algehyne Ebrahem A., Alamrani Fahad Maqbul, Seada M. M., Saeed Anwar, Bognár Gabriella

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Unstable Transgene Expression Affects Long-Term Efficacy of the Arabidopsis Immune Receptor EFR to Confer Quantitative Resistance to Citrus Canker Under Field Conditions by Mukesh Jain, Gerald V. Minsavage, Naweena Thapa, Diana M. Horvath, Cyril Zipfel, Gloria A. Moore, Latanya C. Fisher, Vladimir Orbović, Jeffrey B. Jones

“…Surprisingly, when two mature transgenic lines were evaluated under field conditions and exposure to natural infection, both were found to be as susceptible as the wild-type under prevalent pathogen load. …”
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Determination and analysis of the gene expression, involved in the differentiation and functioning of beta cells under the conditions of the development of experimental diabetes of... by T. V. Ivanenko, A. V. Vynokurova

“…The aim of the work is to identify and analyze a panel of genes, involved in the differentiation and functioning of beta cells under the conditions of the development of experimental type 2 diabetes. …”
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P–T-t conditions of successive deformation stages during exhumation of orogenically thickened crust; a case study from the Aar Massif, Central Alps, Switzerland by Edwin Gnos, Josef Mullis, Christian A. Bergemann, Thomas Pettke, Emmanuelle Ricchi, Axel. K. Schmitt

“…The combined data indicate that the oldest cleft quartz generation formed c.15 Ma ago during reverse faulting at 450 °C/440 MPa. A major change in the direction of the regional stress field linked with onset of dextral strike-slip movements along the Rhone-Simplon-Centovalli fault system then led to predominant dextral strike-slip faulting starting at c. 12–11 Ma, at P–T conditions between 375 °C/320 MPa and 330 °C/230 MPa. …”
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Comprehensive genomic characterization and differential expression analysis of m6A RNA methylation regulatory proteins (writers, readers, and erasers) in Suaeda Salsa under abiotic... by Yuke Ma, Huijuan Yin, Wenhui Guo, Bao Li, Yu Chen, Jingjing Zhang, Kongshu Ji, Qiong Yu

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X-Ray Crystal and Cryo-Electron Microscopy Structure Analysis Unravels How the Unique Thylakoid Lipid Composition Is Utilized by Cytochrome <i>b</i>₆<i>f</i> for Driving... by Radka Vladkova

“…It introduces a novel and simple approach for reversible protein reorganization driven purely by biophysical mechanisms, with promising implications for various membrane-based applications.…”
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Analysis of Evolution Structure of a Squall Line in Zhejiang Province Based on Multi-band Radar Observation by QIAN Zhuolei, YAN Peiwen, LI Feng, HUANG Ying

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Numerical Investigation of Spontaneous Ignition During Pressurized Hydrogen Release: Effects of Burst Disk Shape and Opening Characteristics by Wanbing Lin, Zhenhua Wang, Guanghu Wang, Juncheng Jiang, Jingnan Wu, Lei Ni, Ru Zhou, Mingguang Zhang, Liang Ma

“…To address the risk of spontaneous ignition during a high-pressure release, three-dimensional (3D) numerical simulations are systematically conducted to investigate the effects of burst conditions on spontaneous ignition behavior. Eight simulation cases are considered, involving two opening processes (instantaneous and 10-step-like), three burst disk shapes (flat, conventional domed, and reverse domed), and five opening ratios (1, 0.8, 0.6, 0.4, and 0.2). …”
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Gene networks governing the response of a calcareous sponge to future ocean conditions reveal lineage‐specific XBP1 regulation of the unfolded protein response by Niño Posadas, Cecilia Conaco

“…Alternative dimerization between these XBP1 gene products suggests a clathrinid‐specific mechanism to reversibly sequester the transcription factor into an inactive form, enabling the rapid regulation of pathways linked to the UPR in clathrinid calcareous sponges. …”
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Classification of Individuals With COVID-19 and Post–COVID-19 Condition and Healthy Controls Using Heart Rate Variability: Machine Learning Study With a Near–Real-Time Monitoring C... by Carlos Alberto Sanches, Andre Felipe Henriques Librantz, Luciana Maria Malosá Sampaio, Peterson Adriano Belan

“… BackgroundHeart rate variability (HRV) is a validated biomarker of autonomic and inflammatory regulation and has been associated with both acute COVID-19 and post–COVID-19 condition. Although reverse transcription polymerase chain reaction remains the diagnostic gold standard for acute infection, there is a lack of accessible, noninvasive physiological tools to support ongoing monitoring and stage differentiation of COVID-19 and its sequelae. …”
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Survival Strategies of <i>Staphylococcus aureus</i>: Adaptive Regulation of the Anti-Restriction Gene <i>ardA</i>-H1 Under Stress Conditions by Flavia Costa Carvalho de Andrade, Mariana Fernandes Carvalho, Agnes Marie Sá Figueiredo

“…This study investigates the regulatory mechanisms controlling <i>ardA-</i>H1 expression in <i>S. aureus</i> under various stress conditions, including acidic pH, iron limitation, and vancomycin exposure, and explores the roles of the Agr quorum sensing system. …”
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Treatment of atypical hemolytic uremic syndrome with eculizumab in a patient presenting with neuropsychiatric prodrome: a case report by Hanze Yang, Jingdong Zhang, Hao Wu, Hongzhao Xu, Zhonggao Xu

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Structural and Functional Fundamentals of Alcoholic Disease by V. S. Paukov, T. M. Voronina, Yu. A. Kirillov, E. M. Malysheva

“…It is noted that, while the morphological changes are considered to be reversible during the first two stages, they become irreversible at the stage of alcoholism.Conclusion. …”
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Individualized intervention and growth dynamics assessment in TRAP sequence with conjoined twins based on radiofrequency ablation by Hua Lai, Huiting Zhu, Jinliang Zhang, Juhua Xiao, Mengjiao Liu, Danping Liu, Zengming Li, Xin Zhou

“…Abstract Background Twin reversed arterial perfusion (TRAP) sequence with conjoined twins (CTs) represents an exceedingly rare and critical complication in monochorionic monoamniotic (MCMA) twin pregnancies. …”
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Mesurer l’impact du travail sur la santé : du longitudinal, oui, mais lequel ? by Thomas Coutrot, Loup Wolff

“…This lack of efficiency is probably due to the greatest reversibility of the disorders in the case of disappearance of the exposure, a phenomenon which the “standard” model confuses with negative correlation between the exposure and the disorder.…”
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ATP Supply from Cytosol to Mitochondria Is an Additional Role of Aerobic Glycolysis to Prevent Programmed Cell Death by Maintenance of Mitochondrial Membrane Potential by Akane Sawai, Takeo Taniguchi, Kohsuke Noguchi, Taisuke Seike, Nobuyuki Okahashi, Masak Takaine, Fumio Matsuda

“…This mechanism likely contributes to cell survival under conditions of fluctuating oxygen availability.…”
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Energy savings in SWRO desalination via PRO hybridization: a parametric study by Ahmed S. Alghamdi, Amr Mohamed Mahmoud, Sultan Ahmed

“…This study investigates the potential for energy reduction in a full-scale Seawater Reverse Osmosis (SWRO) desalination plant through hybrid integration with Pressure Retarded Osmosis (PRO). …”
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Analysis of Sandbar–Trough Bed Level Changes Under Regular Wave Conditions—A Case Study of Ten-Mile Silver Beach, Hailing Island, China by Xiaodong Bian, Zhiqiang Li, Yan Sun, Daoheng Zhu, Tao Chen, Chunhua Zeng

“…Understanding the evolution of the sandbar–trough system under regular wave conditions is essential for revealing the dynamic responses of coastal morphology in non-extreme environments and provides a scientific basis for long-term beach stability assessments and coastal erosion management. …”
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