Generation of a fluorescent hESC reporter line (Kle033-A-1) for the isolation of distinct midbrain progenitor cell types by Emilía Sif Ásgrímsdóttir, Ernest Arenas

“…Midbrain dopaminergic (mDA) neurons derived from human pluripotent stem cells (hPSCs) offer a promising cell source for cell replacement therapy in Parkinson’s disease (PD). Single-cell RNA sequencing (scRNA-seq) of the developing human ventral midbrain has identified four cell types expressing markers used to define correctly patterned mDA progenitors. …”
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Experimental Study on the Shear Strength of Dune Sand Concrete Beams by Zhiqiang Li, Rui Ma, Gang Li

“…The failure mode, crack pattern, load deflection, and stirrup strain were investigated. …”
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Syntactic Analysis of Spatial Structure Characteristics of Traditional Villages Along the Yellow River in Western Shanxi Province by Chenge GAO, Fang WANG

“…After undergoing diachronic iterative changes and processes such as the anchoring, disappearance, replacement, and permeation of spatial functions, these traditional villages exhibit diverse spatial structure characteristics.ConclusionThe internal spatial structure of traditional villages is subject to complex adaptive changes influenced by local internal and external spatial factors, which in turn affects aspects such as spatial use, pedestrian distribution, social interaction, and behavioral patterns. …”
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Mechanical behavior of waste rock-based geopolymer as a sustainable backfill material: Strength evolution and fracture mechanisms by Yu Tian, Zhile Wang, Shiyuan Li, Chuning Ji, Chuangang Gong, Abdoul Wahab, Shengkang Zhang, Zhongchen Ao

“…Results demonstrated high-temperature treatment improves the compressive and flexural strength of waste rock-based paste, with calcined waste rock powder effectively enhancing fly ash reactivity. Increasing slag replacement reduces compressive strength linearly, with 5 MPa decline per 10 % increase in slag content. …”
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Accuracy of information on the underlying cause of death: An analysis in Colombia during the COVID-19 pandemic in 2021. by Pablo Chaparro-Narváez, Jessika Alexandra Manrique Sanchez, Laura Berrio-Parra, Diana Carolina Urrego Ricaurte, Luis José Torres-Rojas, Nidia Patricia Orjuela Cantor, Claudia Patricia Mora Aguirre, Yesid Rojas Quevedo, Clara Suárez, Carlos Castañeda-Orjuela

“…Measures of concordance, patterns of false positives and negatives, and a kappa value were utilized as metrics to evaluate the death certificates quality.…”
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Investigation of the Flow Field Characteristics of Aortic Bileaflet Mechanical Heart Valves with Different Leaflet Shapes Using PIV by Y. Qiang, T. C. Duan, M. Z. Zhang, L. Qi, L. J. Wei

“…Non-physiological flow patterns generated by bileaflet mechanical aortic valves are closely associated with thromboembolism following valve replacement surgery. …”
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Management and Outcome of Patients with Acetabular Fractures: Associated Injuries and Prognostic Factors by Do-Hyun Yeo, Jong-Keon Oh, Jae-Woo Cho, Beom-Soo Kim

“…The posterior wall and both column fracture were the most common (37.8%) fracture patterns. Excellent and good clinical grades of MDA included 28 patients (75.6%) and fair and poor grades included nine (24.3%), respectively. …”
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Rapid intraspecific evolution of miRNA and siRNA genes in the mosquito Aedes aegypti. by Scott A Bernhardt, Mark P Simmons, Ken E Olson, Barry J Beaty, Carol D Blair, William C Black

“…Silencing of exo-siRNA pathway genes in mosquitoes orally infected with arboviruses leads to increased viral replication, but little is known about the comparative patterns of molecular evolution among the exo-siRNA and miRNA pathways genes in mosquitoes. …”
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Identification of druggable targets in acute kidney injury by proteome- and transcriptome-wide Mendelian randomization and bioinformatics analysis by Jiachen Liu, Dianjie Zeng, Yinhuai Wang, Fei Deng, Shuiqing Wu, Zebin Deng

“…Abstract Background Acute kidney injury (AKI) remains a critical condition with limited therapeutic options, predominantly managed by renal replacement therapy. The challenge of developing targeted treatments persists. …”
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Combined Analysis of Endothelial, Hematopoietic, and Mesenchymal Stem Cell Compartments Shows Simultaneous but Independent Effects of Age and Heart Disease by Carine Ghem, Lucinara Dadda Dias, Roberto Tofani Sant’Anna, Renato A. K. Kalil, Melissa Markoski, Nance Beyer Nardi

“…The study included 36 patients referred for coronary artery bypass grafting or valve replacement surgery. A decreased frequency of stem cells was observed in both groups of patients. …”
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Methodological and environmental implications for coastal soil identification as support for land management by Gabriel Phelipe Nascimento Rosolem, Yuzi Anaí Zanardo Rosenfeldt, Esdras Coivo Vilella, Daniel Alexandre Heberle, Arcângelo Loss

“…The study focused on identifying ecological patterns and impacts associated with acid-sulfate soils. …”
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Temporal Trends in Internal vs. External Referrals for TAVR in a Large Academic Center: Patients Characteristics and Outcomes by Aurelie Merlo, Audrey Khoury, Mohsin Shah, Tabitha Linville, John Ikonomidis, Matthew Cavender, John Vavalle, Thomas Caranasos

“…This study presents the referral pattern to a large TAVR center in North Carolina. …”
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Reduced periprosthetic fracture rate for a cemented anatomical versus a tapered polished stem in hip arthroplasty: A 6‐year follow‐up of a prospective observational cohort study... by Anna Josefsson, Michael Axenhus, Raéd Itayem, Sebastian Mukka, Martin Magnéli

“…Methods A prospective single‐centre cohort study included 1077 patients operated with a cemented hip replacement at Danderyd Hospital, Stockholm, Sweden, between 2012 and 2015. …”
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Trajectory-based analysis of early mechanical ventilation PEEP levels and physiological parameter trajectories in ARDS patients and their association with the occurrence of gastroi... by Shi-Tao Huang, Kai-Hua Yu, Xiong-Bin Ma, Yi-Bo Sun, Zhong-Ya Huang, Di Chen, Hong-Lei Li, Li-Ping Liu

“…Kaplan–Meier curves revealed a consistent pattern with Group 1 showing the highest cumulative incidence of GI events. …”
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Mapping Disorders with Neurological Features Through Mitochondrial Impairment Pathways: Insights from Genetic Evidence by Anna Makridou, Evangelie Sintou, Sofia Chatzianagnosti, Iasonas Dermitzakis, Sofia Gargani, Maria Eleni Manthou, Paschalis Theotokis

“…A comprehensive table synthesizes genetic causes, inheritance patterns, and neurological manifestations across disorders. …”
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Docosahexaenoic Acid (DHA) Down-regulates Cellular, and Exosomal Overexpressed Mammalian Target of Rapamycin (mTOR) in Breast Cancer Cells Under Hypoxic Condition by Sepideh Maralbashi, Farhad Salari, Cynthia Aslan, Houman Kahroba, Milad Asadi, Zahra Asghari, Tohid Kazemi

“…Also, miRNA replacement therapy would be useful by suppressing the expression of mTOR in BC treatment.…”
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Flow analysis of steady state forward flow of aortic valve prostheses using Particle Image Velocimetry by Lenz Christopher, Borowski Finja, Oldenburg Jan, Brandt-Wunderlich Christoph, Stiehm Michael, Schmitz Klaus-Peter

“…Transcatheter aortic valve replacement (TAVR) has become the standard therapy for aortic valve stenosis in patients with high surgical risk. …”
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Sedimentary Characteristics and Petroleum Geological Significance of the Middle–Upper Triassic Successions in the Wushi Area, Western Kuqa Depression, Tarim Basin by Yahui Fan, Mingyi Hu, Qingjie Deng, Quansheng Cai

“…This study focuses on the Wushi Sag, systematically analyzing the sedimentary facies types, the evolution of sedimentary systems, and the distribution patterns of the Triassic Kelamayi and Huangshanjie formations. …”
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Abnormal hyperactivity of specific striatal ensembles encodes distinct dyskinetic behaviors revealed by high-resolution clustering by Cristina Alcacer, Andreas Klaus, Marcelo Mendonça, Sara F. Abalde, Maria Angela Cenci, Rui M. Costa

“…Summary: L-DOPA-induced dyskinesia (LID) is a debilitating complication of dopamine replacement therapy in Parkinson’s disease and the most common hyperkinetic disorder of basal ganglia origin. …”
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Decision-Making Model for Life Cycle Management of Aircraft Components by Igor Kabashkin, Vitaly Susanin

“…These studies showcase the model’s versatility in handling different failure patterns and maintenance requirements. This study introduces a data-driven decision-making framework for optimizing the life cycle management of aircraft components, focusing on reliability, cost-effectiveness, and safety. …”
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