A suppression-modification gene drive for malaria control targeting the ultra-conserved RNA gene mir-184 by Sebald A. N. Verkuijl, Giuseppe Del Corsano, Paolo Capriotti, Pei-Shi Yen, Maria Grazia Inghilterra, Prashanth Selvaraj, Astrid Hoermann, Aida Martinez-Sanchez, Chiamaka Valerie Ukegbu, Temesgen M. Kebede, Dina Vlachou, George K. Christophides, Nikolai Windbichler

“…Here we present a highly efficient homing gene drive in the African malaria vector Anopheles gambiae that targets the microRNA gene mir-184 and combines suppression with modification. …”
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Queen conch aquaculture remains a conservation symbol and is not yet a fisheries solution by Andrew Kough, Shayle Matsuda, Richard Appeldoorn, Erik Boman, Kayley Galassini, Gabriel Delgado, Nelson Ehrhardt, Robert Glazer, Gaya Gnanalingam, Alexander Tewfik, Allan Stoner

“…Estimates of reproduction to achieve replacement suggest a greater yield from properly protecting natural breeding aggregations. …”
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Cellular and humoral response to SARS-CoV-2 vaccine BNT162b2 in adults with Chronic Kidney Disease G4/5. by Anja Rosdahl, Fredrika Hellgren, Torbjörn Norén, Jessica Smolander, Ursula Wopenka, Karin Loré, Helena Hervius Askling

“…This suggests that immunization prior to RRT is efficient and motivated. (EudraCT-nr 2021-000988-68).…”
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Donor-π-Conjugated Spacer-Acceptor Dye-Sensitized Solid-State Solar Cell Using CuI as the Hole Collector by D. N. Liyanage, K. D. M. S. P. K. Kumarasinghe, G. R. A. Kumara, A. C. A. Jayasundera, K. Tennakone, B. Onwona-Agyeman

“…Dye-sensitized solid-state solar cells (DSSCs) replacing the liquid electrolyte with a p-type semiconductor have been extensively examined to solve the practical problems associated with wet-type solar cells. …”
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A rapid algorithm for millimeter-wave near-field three-dimensional image reconstruction based on FiNUFFT by Letian Zeng, Sheng Zhang, Yuanyuan Huai, Qi Mao, Jingzhao Li, Zhaohui Luo, Yunhuai Zou

“…The proposed algorithm is designed to ensure the reconstruction of high-quality 3D images, with the potential to significantly enhance the efficiency of computation. This provides a more efficient and accurate solution for millimeter-wave near-field 3D imaging. …”
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Self-adaptive evolutionary neural networks for high-precision short-term electric load forecasting by Muhammad Abbas, Yanbo Che, Sarmad Maqsood, Muhammad Zain Yousaf, Mustafa Abdullah, Wajid Khan, Saqib Khalid, Mohit Bajaj, Mohammad Shabaz

“…However, these learnable activation functions introduce a new set of hyperparameters that require careful optimization to ensure efficient training and manage network complexity. To address this, SADE dynamically tunes these hyperparameters, ensuring an optimal balance between accuracy, complexity, and training efficiency. …”
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Construction strategies for 3D printed cardiac tissue repair materials and their application potential by Mingru Kong, Zhen Wu, Zeliang Zheng, Binrui Zhang, Yuting Zeng, Hao Deng, Dongyi Feng, Wenjun Zhang, Congru Li, Xiaodong Fu, Leyu Wang

“…Combined with specific research cases, this review reveals the progress of 3D printing in heart valve replacement, heart patches, vascular stent manufacturing, and composite material development, especially the potential of carbon‐based conductive materials, biomass‐based materials, and bio‐based materials in cardiac tissue repair. …”
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Thermal Conductivity of Sustainable Earthen Materials Stabilized by Natural and Bio-Based Polymers: An Experimental and Statistical Analysis by Rizwan Shoukat, Marta Cappai, Giorgio Pia, Tadeusz Kubaszek, Roberto Ricciu, Łukasz Kolek, Luca Pilia

“…The main objective of bio-stabilization is to substitute high-energy-intensive building materials with more green, thermally efficient substitutions, ultimately reducing indirect emissions. …”
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Research progress and thinking on specialized drilling technology in underground coal mine by Jianlin LIU, Fei LIU, Quanxin LI, Jun FANG, Guiqin LIU, Siyi WANG, Zhiwei CHU, Jianguo ZHAO, Weifeng YANG

“…The typical application scenarios of specialized drilling technology are summarized, such as precise gas control in soft-fragmented coal seam, replacing tunnel with borehole for relieved gas drainage in roof, mine water detection and release, and grouting reinforcement of water-resisting layer.It delves into the key technical challenges encountered during implementation.Focusing on drilling equipment upgrade, innovative drilling method, and drilling parameter optimization, the study comprehensively reviews the current development status, critical technological advancements, and practical outcomes.The specialized drilling technology suitable for soft-fragmented coal seam, hard rock strata, and fractured and water sensitive strata are outlined, and the existing technical bottlenecks and challenges are identified.Given the evolving trends of diversified demand, equipment intelligence, and region-specific adaptation in underground specialized drilling technology, future research priorities are proposed: ① To enhance air directional drilling technology for soft-fragmented coal seam to improve formation adaptability and process compatibility. ② To advance high-efficiency drilling acceleration technology and tool for hard rock strata to boost rock-breaking efficiency and service life of impact drilling tool. ③ To overcome theoretical and technical barrier in pressure-controlled drilling under near-horizontal condition to strengthen borehole formation capability in fractured and water-sensitive strata of roof or floor. ④ To accelerate the improvement of the reliability and stability of intelligent drilling technology and equipment in underground coal mine, and promote the realization of the transformation of specialized drilling technology from equipment intelligence to engineering intelligence. ⑤ To research and constructe specialized drilling technology system of regional, mining area and mine, and promote their wide application and in-depth development in the coal mining industry.The study can provide an important reference for the technological innovation and efficiency improvement of drilling process in underground coal mine.…”
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High accuracy identification of maize seed varieties based on a lightweight improved YOLOv8 by Siqi Niu, Xiaolin Xu, Ao Liang, Yuliang Yun, Fengqi Hao, Jinqiang Bai, Wenyi Sheng, Dexin Ma

“…Firstly, the backbone was replaced with FasterNet, which reduced redundant computation and memory access, allowing more efficient extraction of spatial features. …”
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Preimplantation genetic testing for four families with severe combined immunodeficiency: Three unaffected livebirths by Lingyun Zhang, Lei Feng, Hao Shi, Wenbin Niu, Yanchi Wang, Bei Bu, Yidong Liu, Xiao Bao, Wenyan Song, Haixia Jin, Yingpu Sun

“…Conclusion This study revealed that karyomapping is an efficient approach for identifying SCID. Through PGT-M with karyomapping linkage analysis, healthy babies were born to families carrying mutations in the SCID pathogenic gene.…”
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YOLO-SRMX: A Lightweight Model for Real-Time Object Detection on Unmanned Aerial Vehicles by Shimin Weng, Han Wang, Jiashu Wang, Changming Xu, Ende Zhang

“…By synthesizing these principles, a novel composite receptive field lightweight convolution, DRFAConvP, is proposed to further optimize multi-scale feature fusion efficiency and promote model lightweighting. Finally, the Wise-IoU loss function is adopted to replace the traditional bounding box loss. …”
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URT-YOLOv11: A Large Receptive Field Algorithm for Detecting Tomato Ripening Under Different Field Conditions by Di Mu, Yuping Guou, Wei Wang, Ran Peng, Chunjie Guo, Francesco Marinello, Yingjie Xie, Qiang Huang

“…First, the UniRepLKNet block replaces the C3k2 module in the standard network, improving computational efficiency, expanding the receptive field, and enhancing multi-scale target recognition. …”
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Review on the properties and mechanisms of asphalt modified with bio-oil and biochar by Xinxing Zhou, Ziyang Zhang, Haopeng Wang, Meizhu Chen, Shaopeng Wu, Song Xu, Xinglin Zhou, Maoping Ran, Linglin Li, Guangjun Lu, Zhibin Ma

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The IAA-Producing Rhizobacterium <i>Bacillus</i> sp. SYM-4 Promotes Maize Growth and Yield by Yumeng Song, Qifei Chen, Juan Hua, Shaobin Zhang, Shihong Luo

“…In this study, the replacement of a proportion of conventional fertilizer with a microbial substitute demonstrates a new technique with great potential for the green and efficient cultivation of maize.…”
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Study on Operating Modes of a Biofuel Diesel Engine by V. A. Likhanov, O. P. Lopatin

“…The diesel engine was started using rapeseed oil, after which the ethanol supply was switched on, replacing the rapeseed oil until the set optimum value was reached. …”
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Optimal Design of a Liquid Hydrogen Centrifugal Pump Impeller by Catur Harsito, Jeong-Eui Yun, Joon-Young Shin, Jae-Min Kim

“…Fossil energy sources are now being replaced with renewable energy, and hydrogen is one of such alternatives. …”
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Studying the performance of YOLOv11 incorporating DHSA BRA and PPA modules in railway track fasteners defect detection by Chengwei Zhang, Jiawei Zhu, Yihao Ma, Qingmei Huang

“…Abstract With the development of railway transportation and the advancement of deep learning, object detection algorithms are increasingly replacing manual inspection of track fasteners. However, current algorithms struggle with low accuracy in complex weather conditions or low-contrast backgrounds. …”
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Influence of Innovative Digital Tools in Retail on the Purchasing Behaviour: An Empirical Study Based on a Customer Observation and on a Customer Survey by Daniela Ludin, Sophia Bayha, Alexander Loew, Mike Tilmann

“…Innovative digital tools, such as self-checkout systems, are becoming increasingly important and are not only influencing process efficiency but also the purchasing behaviour of consumers. …”
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Lightweight vision transformer model for pine wilt disease detection using aerial RGB image and adversarial data augmentation by Qing Li, Wenhui Chen

“…Finally, MPDIoU loss replaces GIoU loss, improving bounding box regression accuracy in overlapping scenarios. …”
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