Synthesis and kinetic evaluation of analogs of (E)-4-amino-3-methylbut-2-en-1-yl diphosphate, a potent inhibitor of the IspH metalloenzyme by Petit, Benoît Eric, Jobelius, Hannah, Bianchino, Gabriella Ines, Guérin, Mélina, Borel, Franck, Chaignon, Philippe, Seemann, Myriam

“…After synthesis of the derivatives, enzymatic assays demonstrated that none of these AMBPP analogs is an efficient IspH inhibitor.…”
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Advances in data‐assisted high‐throughput computations for material design by Dingguo Xu, Qiao Zhang, Xiangyu Huo, Yitong Wang, Mingli Yang

“…Abstract Extensive trial and error in the variable space is the main cause of low efficiency and high cost in material development. The experimental tasks can be reduced significantly in the case that the variable space is narrowed down by reliable computer simulations. …”
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Photon number resolution without optical mode multiplication by Vetlugin Anton N., Martinelli Filippo, Dong Shuyu, Soci Cesare

“…Yet, these methods suffer from an inherent trade-off between the efficiency of photon number discrimination and photon detection rate. …”
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Enhancing Power Quality in Distributed Energy Resource Systems Through Permanent Magnet Retrofitting of Single-Phase Induction Motors by Huan Wang, Fangxu Han, Renjie Fu, Bo Zhang

“…However, the power quality is often compromised by inefficient customer-side equipment, such as single-phase induction motors, which suffer from low efficiency and poor power factor. To address this issue, this paper proposes a permanent magnet retrofitting method for single-phase induction motors, which replaces the squirrel-cage rotor with a permanent magnet rotor while preserving the original stator and winding structure. …”
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Generation of Zebrafish Maternal Mutants via Oocyte-Specific Knockout System by Chong Zhang, Wenlu Wei, Tong Lu, Yizhuang Zhang, Jiaguang Li, Jiasheng Wang, Aijun Chen, Fenfen Wen, Ming Shao

“…Here, we provide an alternative approach to generate zebrafish maternal mutants rapidly and efficiently by introducing four tandem sgRNA expression cassettes into Tg(zpc:zcas9) embryos. …”
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Digital rural construction and agricultural green total factor productivity: the role of land finance, land resource misallocation, and agricultural technology innovation by Zhenyang Zhang, Zhenyang Zhang, Tianxiang Hu, Jinghui He

“…The effects of DRC on AGTFP are notably more pronounced in the central and western regions of China, non-major grain-producing areas, and regions with lower land transfer efficiency. Our insights clarify the influence pathways through which DRC facilitates the enhancement of AGTFP, offering fresh theoretical insights and practical implications for further guiding DRC and leveraging the efficiency of AGTFP.…”
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Improved Trimming Ant Colony Optimization Algorithm for Mobile Robot Path Planning by Junxia Ma, Qilin Liu, Zixu Yang, Bo Wang

“…Additionally, the traditional heuristic function is replaced with an artificial potential field attraction function, dynamically adjusting the potential field strength to enhance search efficiency. …”
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Antenna Optimization Design Based on Deep Gaussian Process Model by Xin-Yu Zhang, Yu-Bo Tian, Xie Zheng

“…It is shown that the DGP network model proposed in this paper can replace the electromagnetic simulation software in the optimization process, so as to reduce the time required for optimization while ensuring the design accuracy.…”
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Evaluación del desempeño productivo y económico de pollos de engorde alimentados con harina de gliricidia sepium by Dixon Fabián Flórez-Delgado, Dubel Reinaldo Cely-Leal

“…The linear and quadratic effects of replacing CFB with G. sepium were evaluated using orthogonal contrasts. …”
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Robust Schnorr-based subgroup multi-signature scheme by ZHANG Zhenqi, ZHU Qiuchi, WANG Zhiwei

“…However, current consensus mechanisms have encountered three issues: low consensus efficiency, low reliability and security, and high computational complexity. …”
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USE OF RENEWABLE SOURCES OF ENERGY FOR NUTRITION OF OWN REQUIREMENTS OF OIL PIPELINE by K. V. Suslov, I. N. Shushpanov, D. V. Vorontsov

“…To achieve this goal, it is proposed to replace diesel generators with plants using renewable energy sources. …”
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Improved YOLOv8n based helmet wearing inspection method by Xinying Chen, Zhisheng Jiao, Yuefan Liu

“…Additionally, the original Detect structure is substituted with the PC-Head decoupling head, leading to a significant reduction in parameter count and an enhancement in model efficiency. Moreover, the original Detect structure is replaced by the PC-Head decoupling head, significantly reducing parameter count and enhancing model efficiency. …”
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MINI Logic 1-Bit Adder: A Comparison with Hybrid NMOS-Memristor-Logic Styles Using Ta2O5/Al2O3 Based RRAM Device by NITHYA, N., PARAMASIVAM, K.

“…By replacing conventional PMOS transistors with memristors in CMOS logic, the study leverages the high-off resistance and low-voltage operation of RRAM devices to develop more compact and energy-efficient circuits. …”
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Optimizing the axis ratio of elliptical PCM encasement for enhanced thermal performance in radiant floor heating systems by Zhenyu Wang, Weijun Gao, Jian Sun, Yanna Gao

“…However, traditional encased PCM radiant floor heating systems (RFHS) exhibit drawbacks including slow thermal response, low thermal efficiency, and excessive structural layer thickness. …”
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An attractive path to use of green resources for production of antibacterial and antioxidant wool yarns by Somayeh Baseri

“…The influence of the main process parameters on the dyeing efficiency was evaluated and an efficient mathematical model was developed to provide the best dyeing conditions at minimum materials and energy costs. …”
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Photon shielding properties of TiO2 and WO2 incorporated into ordinary concrete: Evaluation for radiotherapy applications by Cecília Borges Moreto, Eduardo De Paiva

“…Results demonstrate that concrete enhanced with TiO2 and WO2 shows a significant improvement in photon shielding efficiency compared to conventional concrete, particularly at higher photon energy. …”
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Exploring the hydrophobic effects of quaternary ammonium copolymers on corrosion of casing and tubing steel in acidic solution. by Ghadeer Mubarak, Chandrabhan Verma, Mohammad A Jafar Mazumder, Imad Barsoum, Akram Alfantazi

“…The results showed that AMCs act as efficient corrosion inhibitors, with over 90% inhibition efficiency ([Formula: see text] ) at 20 ppm concentration. …”
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Dexamethasone administration restored growth in dairy calves exposed to heat stress by Z. Yu, J.M. Cantet, M.R.R. Nair, A.G. Ríus

“…An ENV × INT interaction showed that heat stress with saline decreased ADG by 35% and tended to decrease feed-use efficiency by 36%, but the use of dexamethasone to treat heat stress restored ADG and feed-use efficiency comparable to their basal levels. …”
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First Responder Virtual Reality Simulator to train and assess emergency personnel for mass casualty response by Nicholas E. Kman, Alan Price, Vita Berezina‐Blackburn, Jeremy Patterson, Kellen Maicher, David P. Way, Jillian McGrath, Ashish R. Panchal, Katherine Luu, Alex Oliszewski, Scott Swearingen, Douglas Danforth

“…Eventually, we hope that the First Responder system will serve both as an effective replacement for expensive conventional training methods as well as a safe and efficient platform for research on current triage protocols.…”
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Unlocking Testosterone Production by Biotransformation: Engineering a Fungal Model of <i>Aspergillus nidulans</i> Strain Deficient in Steroid 11α-Hydroxylase Activity and Expressin... by Lidia Ortega-de los Ríos, Luis Getino, Beatriz Galán, José Luis García, José M. Luengo, Alejandro Chamizo-Ampudia, José M. Fernández-Cañón

“…Testosterone holds significant medical and economic importance, with the global market for testosterone replacement therapies valued at approximately USD 1.9 billion in 2023. …”
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