Combining genetic and non-genetic factors to predict the risk of pancreatic cancer in patients with new-onset diabetes mellitus by Yu Zhou, Zhuo Wu, Liangtang Zeng, Rufu Chen

“…We developed a NODM-PC risk prediction model to stratify PC risk in patients with NODM. Methods This study utilized data from the UK Biobank, including 238 NODM-PC cases and 14,825 cancer-free T2DM controls. …”
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ENVIRONMENTAL ASPECTS OF MODERNIZATION OF HIGH POWER WATER-HEATING BOILERS by P. M. Glamazdin, D. P. Glamazdin, Yu. P. Yarmolchick

“…As a result of experiments, it was observed that if a decrease of the twist rate takes place the emission of nitrogen oxides is reduced. The methods of further reduction of emissions of nitrogen oxides have been determined, viz. the device recirculation of flue gases by mixing them in a blast air; conducting the process at low excess of air with controlled chemical underburning when complete oxidation of carbon to CO2 accomplishes outside the furnace at the initial section of the convection part; hydration of blowing air into the humidification amount of 1.5–2.0 % of the nominal output of the boiler.…”
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Experimental Study of the Kinematics of a Double-Row Planetary Mechanism Using Two Elliptical External Gears by A. A. Prikhodko, N. N. Belina, A. V. Novitskiy, M. M. Shchetinin

“…The experimental study of kinematics was performed on a laboratory stand containing a model of a planetary mechanism with a set of replaceable gear wheels, absolute encoders on the input and output shafts of the mechanism, a controller, and a PC for recording and processing the signal. …”
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Retinal Vessel Diameter Reductions Are Associated with Retinal Ganglion Cell Dysfunction, Thinning of the Ganglion Cell and Inner Plexiform Layers, and Decreased Visual Field Globa... by Andrew Tirsi, Nicholas Leung, Rohun Gupta, Sungmin Hong, Derek Orshan, Joby Tsai, Corey Ross Lacher, Isabella Tello, Samuel Potash, Timothy Foster, Rushil Kumbhani, Celso Tello

“…An identical regression analysis where the RVD was replaced with the PERG parameters showed a significant association between the MagD and almost all GCI-IPLT measurements. …”
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Current Applications, Challenges, and Future Directions of Artificial Intelligence in Emergency Medicine: A Narrative Review by Mehrdad Farrokhi, Amir H Fallahian, Erfan Rahmani, Ali Aghajan, Morteza Alipour, Parisa Jafari Khouzani, Hossein Boustani Hezarani, Hamed Sabzehie, Mohammad Pirouzan, Zahra Pirouzan, Behnaz Dalvandi, Reza Dalvandi, Parisa Doroudgar, Habib Azimi, Fatemeh Moradi, Amitis Nozari, Maryam Sharifi, Hamed Ghorbani, Sara Moghimi, Fatemeh Azarkish, Soheil Bolandi, Hooman Esfahani, Sara Hosseinmirzaei, Arezou Niknam, Farzaneh Nikfarjam, Parham Talebi Boroujeni, Mahyar Noorbakhsh, Parham Rahmani, Fatemeh Rostamian Motlagh, Khadijeh Harati, Masoud Farrokhi, Sina Talebi, Lida Zare Lahijan

“…Since emergency medicine involves various clinical decision-making scenarios based on classifications, flowcharts, and well-structured approaches, future well-designed prospective studies are necessary to achieve the goal of replacing conventional methods with new AI and machine learning techniques. …”
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Estimating the prediction ability of reverse degree-based entropy indices for the physicochemical properties of lymes disease drugs by Guoping Zhang, Guoping Zhang, Yali Li, Yali Li, Abdul Rauf, Muhammad Aamir Afzal, Parvez Ali, Adnan Aslam

“…Unlike traditional experimental methods mandated by regulatory authorities for Chemistry, Manufacturing, and Controls (CMC) processes, our approach provides a supplementary predictive framework to streamline early-stage drug property estimation. …”
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Aggregate index of systemic inflammation tied to increased fatty liver disease risk: insights from NHANES data by Meng Zhang, Yuan Yuan, Chenglong Wang, You Huang, Mingli Fan, Xiangling Li, Zujie Qin

“…Participants were chosen based on the availability of controlled attenuation parameter (CAP) scores derived from transient elastography (TE), a technique utilized for assessing liver steatosis. …”
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Feasibility of Long-Term Physical Activity Measurement With a Wearable Activity Tracker in Patients With Axial Spondyloarthritis: 1-Year Longitudinal Observational Study by Emil Eirik Kvernberg Thomassen, Anne Therese Tveter, Inger Jorid Berg, Eirik Klami Kristianslund, Andrew Reiner, Sarah Hakim, Laure Gossec, Gary J Macfarlane, Annette de Thurah, Nina Østerås

“…ObjectivesThis study aimed to explore the feasibility of recording physical activity using a wearable activity tracker and describe wear-time patterns among patients with axSpA. MethodsData from a randomized controlled trial (NCT: 05031767) were analyzed. …”
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Growth Promotion and Economic Benefits of the Probiotic <i>Lactiplantibacillus plantarum</i> in Calves by Kazumasa Osawa, Saya Taharaguti, Chiaki Ito, Tadashi Takino, Katsuro Hagiwara

“…The LP1 group was fed lyophilized LP1 (10⁹ CFU/head/day) in milk replacer for 40 days. The CN group was fed the same diet only. …”
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Prognostic stratification in myocardial infarction using the modified CONUT score: a multidimensional biomarker from the MIMIC-IV cohort by Weixu Yu, Weixu Yu, Yanting Luo, Qingyuan Cai, Jin Yang, Wanling Deng, Ruimin Dong, Xujing Xie

“…We introduced an innovative modified Controlling Nutritional Status (mCONUT) score, which replaces total cholesterol with non-HDL cholesterol, aiming to improve the stratification of atherosclerotic risk and to assess its prognostic utility in predicting MI outcomes.MethodsIn this retrospective cohort study, we analyzed a total of 3,730 patients diagnosed with MI, extracted from the MIMIC-IV database, and stratified them into Normal, Mild, and Worse groups based on the mCONUT score. …”
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Flow and heat transfer characteristics of 3D printed sheet and solid triply periodic minimal surfaces porous structures by Jiajie Hu, Wei Xu, Huixin Liang, Jianping Shi, Wenlai Tang, Baocheng Guo, Jiquan Yang, Liya Zhu

“…Abstract Triply periodic minimal surfaces (TPMS) are recently widely employed in thermal engineering applications due to their smooth surfaces, high surface area to volume ratio and mathematically controlled geometry features. Although the sheet-type TPMS shows good heat transfer capacity between the fluid and the skeleton surface, the pressure drop of this structure is large resulting from its partially disconnected surface. …”
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Optimising cardiac surgery outcomes in people with diabetes: the OCTOPuS pilot feasibility study by Richard IG Holt, Katharine Barnard-Kelly, Mayank Patel, Philip Newland-Jones, Suvitesh Luthra, Jo Picot, Helen Partridge, Andrew Cook

“…Although the intervention could be applied to any surgical discipline, cardiothoracic surgery was chosen because 30–40% of those undergoing elective cardiac revascularisation have diabetes. Methods The project had three phases: (1) designing the intervention, (2) a pilot study of the intervention and (3) a multicentre randomised controlled study in United Kingdom cardiothoracic centres to assess whether the intervention could improve surgical outcomes. …”
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ADVANCES IN THALASSEMIA MANAGEMENT AND CHELATION THERAPY by Barbaros Şahin Karagün

“…Clinical studies are constantly being conducted on new treatment methods, which aim to further improve patients' response to treatment. …”
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Utility and cost-effectiveness of LiverMultiScan for MASLD diagnosis: a real-world multi-national randomised clinical trial by Elizabeth Shumbayawonda, Marika French, Jane Elizabeth Carolan, Cayden Beyer, Paula Lorgelly, Dimitar Tonev, Rajarshi Banerjee, Michael H. Miller, Christopher D. Byrne, Janisha Patel, Saima Ajaz, Kosh Agarwal, Johanna Backhus, Minneke J. Coenraad, Jelte J. Schaapman, Andrew Fraser, Miguel Castelo Branco, Stephen Barclay, Matthias M. Dollinger, Daniel J. Cuthbertson, Daniel Forton, Hildo J. Lamb

“…Methods: RADIcAL-1, a 1:1 randomised controlled trial (standard-of-care [SoC] vs. imaging arm [IA; SoC+mpMRI]) included 802 participants from Germany, Netherlands, Portugal and UK. …”
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Abstract 072: Risk Factors for Developing Ischemic Strokes While Taking Non‐Vitamin K Antagonist Oral Anticoagulants by Alvin S. Das, Elif Gokcal, Avia Abramovitz Fouks, Mitchell Horn, Robert Regenhardt, Anand Viswanathan, Aneesh Singhal, Lee Schwamm, Steven Greenberg, Edip Gurol

“…Results 112 patients with ischemic stroke and 94 controls (free of ischemic stroke) were included in the study. …”
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Remission definitions guiding immunosuppressive therapy in rheumatoid arthritis: which is best fitted for the purpose? by Désirée van der Heijde, Laure Gossec, Pedro M Machado, Johannes W G Jacobs, Paco M J Welsing, José António Pereira Da Silva, Ricardo J O Ferreira, Cátia Duarte

“…Objective To assess which definition of remission best predicts good radiographic outcome (GRO) and good functional outcome (GFO) in rheumatoid arthritis, focusing the updated American College of Rheumatology/European Alliance of Associations for Rheumatology criteria.Material and methods Meta-analyses of individual patient data (IPD) from randomised controlled trials (RCTs). …”
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USE OF METHOTREXATE IN PATIENTS WITH CALCIUM PYROPHOSPHATE CRYSTAL DEPOSITION DISEASE by M. S. Eliseev, S. A. Vladimirov, E. L. Nasonov

“…Objective: to compare the efficacy of methotrexate (MTX) and colchicine in patients with chronic arthritis in calcium pyrophosphate crystal deposition disease (CPPDD).Subjects and methods. Data from a controlled prospective cross-sectional study of 10 patients (8 women and 2 men) with chronic arthritis in CPPDD are presented. …”
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Multidimensional comparative evaluation of first-line therapies for extensive-stage small cell lung cancer: a systematic review and network meta-analysis of clinical efficacy and s... by Ziyao Jiang, Fangrui Zhao, Butuo Li, Junyi He, Huiwen Yang, Yuhan Ji, Bing Zou, Jinming Yu, Linlin Wang

“…Conclusions Incorporating anlotinib into the Chemo + PD-L1 regimen can be a viable first-line option for patients with high tumor burden, but cannot fully replace the current first-line standard-of-care (SOC). …”
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Cognitive costs in motor-cognitive performance assessments depend on movement complexity and cognitive task design by Gülsa Erdogan, Lutz Vogt, Florian Giesche, David Friebe, Winfried Banzer, Winfried Banzer, Andreas Mierau, Andreas Mierau, Thorben Hülsdünker, Thorben Hülsdünker

“…Cognitive costs were determined by comparing reaction time and error rate between conditions (cognitive vs. motor-cognitive) while controlling for differences in measurement technology, neuromuscular conduction delay, and movement amplitude. …”
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Optimal early endpoint for second-line or subsequent immune checkpoint inhibitors in previously treated advanced solid cancers: a systematic review by Jingqiu Li, Xiaoding Zhou, Lei Wu, Jiabao Ma, Yan Tan, Songke Wu, Jie Zhu, Qifeng Wang, Qiuling Shi

“…However, early efficacy endpoints are not recommended in RCTs to replace OS.…”
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