New soluble CSF-1R-dimeric mutein with enhanced trapping of both CSF-1 and IL-34 reduces suppressive tumor-associated macrophages in pleural mesothelioma by Sophie Deshayes, Christophe Blanquart, Erwan Mortier, Judith Fresquet, Noémie Joalland, Agnès Quéméner, Romain Humeau, Mike Maillasson, Héloïse LeBihan, Apolline Salama, Séverine Remy, Carole Guillonneau, Ignacio Anegon

“…Thus, there is a need for a more specific and yet integrative approach.Methods A human mutated form of the extracellular portion of CSF-1R was in silico modelized to trap both IL-34 and CSF-1 with higher affinity than the wild-type CSF-1R by replacing the methionine residue at position 149 with a Lysine (M149K). …”
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Small Target Detection Algorithm for UAV Aerial Images Based on Improved YOLOv7-tiny by ZHANG Guanghua, LI Congfa, LI Gangying, LU Weidang

“…This study proposes a small target detection algorithm for UAV aerial images using a ConvMixer detection head based on the improved YOLOv7-tiny to address the problems of missed detection and false detection caused by significant variations in target scale, densely distributed small-sized targets and complex backgrounds in UAV aerial images.MethodsFirst, the activation function LeakyReLU is replaced with SiLU to compensate for the limited nonlinear expression of LeakyReLU and to enhance convergence speed and model generalization during training. …”
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A Comparative study of Daiva's Sin and its Evolution in the Stories of Ancient Iran and Ta'ziehs of Daiva's Tying Thumb Based on Six Poetic Verses by Mahdi mohamadi, Adel Meghdadian, Abolfazl Tajik

“…His greed and arrogance disappeared in this austerity and rationality replaced it.   2.Methodology The method of this research is descriptive-comparative. …”
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Cell therapy in Sjögren's syndrome: opportunities and challenges by Yangyang Lu, Rongjing Shi, Wenqin He, Qi An, Jingwen Zhao, Xinnan Gao, Baiyan Zhang, Liyun Zhang, Ke Xu, Dan Ma

“…Treatment mainly consists of glucocorticoids, disease-modifying antirheumatic drugs and biological agents, which can only control inflammation but not repair the tissue. Therefore, identifying methods to regulate immune disorders and repair damaged tissues is imperative. …”
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Perceived workplace stressors and professional experiences of clinical embryologists working in Italy and Spain: a pilot qualitative study by Giancarlo Astro, Monica Gatti, Mauro Costa, Arianna Cosmelli, Alessandra Alteri, Attilio Anastasi, Attilio Anastasi, Danilo Cimadomo, Danilo Cimadomo, Lucia De Santis, Lucia De Santis, Francesca Gioia Klinger, Francesca Gioia Klinger, Emanuele Licata, Emanuele Licata, Laura Sosa Fernandez, Laura Sosa Fernandez, Giovanna Tomasi, Giovanna Tomasi, Elena Vegni, Irene Cuevas Sáiz, Nicolas Prados, Nicolas Prados, Nicolas Prados, Valerio Pisaturo, Valerio Pisaturo

“…Embryologists manage complex tasks that require high precision and involve significant responsibilities, ranging from manual laboratory procedures to quality control and patient communication. This study aimed to investigate the perceptions of clinical embryologists regarding their occupational well being and to examine their subjective experiences within MAR centers.MethodsQualitative interview study of 28 Italian and Spanish embryologists working at both public and private centers. …”
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Comparative legal analysis of the labor law status of a higher school lecturer by T. F. Vysheslavova, S. A. Lukinova

“…In the process of research, a whole complex of theoretical principles, logical techniques and special methods and means of cognition of state and legal phenomena (historical and legal, comparative legal, etc.) was used. …”
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Spatial pattern of Trees in the Riparian Forests (Case Study: Wildlife Refuge of Karkhe) by Shaieste Gholami

“…This method allows assessment of consistency of spatial patterns as well as the scale at which they are expressed. …”
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Effect of salt stress on yield and yield components in chickpea (Cicer arietinum L. cv. Azad) by Gholam Reza Doraki, Gholam Reza Zamani, Mohammad Hassan Sayyari

“…Also, the highest salinity levels as compared to control reduced pod number by 33.33%, grain yield by 59.83%, 100 grain weight by 44.44% and by 39.34% total dry weight per plant. …”
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The Validity of Cryptocurrency Transactions and the Analysis of Associated Disputes by Hossein Qahari, Javad Hosseinzadeh

“…Cryptocurrency is one of the modern tools that aims to replace money and is sometimes traded among citizens as a commodity or a means of debt payment. …”
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Effect of breathing phase number on the 4D robust optimization for pancreatic cancer intensity modulated proton therapy by Xiaoying Fan, Shuting Wang, Weijie Li, Tengxiang Li, Yong Yin, Tianyuan Dai

“…Abstract Purpose Respiratory movement, as one of the main challenges in proton therapy for pancreatic cancer patients, could not only lead to harm to normal tissues but also lead to failure of the tumor control, resulting in irreversible consequences. Including respiratory movements into the plan optimization, i.e. 4D robust optimization, may mitigate the interplay effect. …”
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Comparison of Clinical Outcomes between the Fourth Day and the Fifth Day Embryo Transfer in IVF/ICSI Cycles: A Retrospective Cohort Study before and after PSM by Yasong Geng, Fangfang Dai, Meiyang Du, Linlin Tao, Haoyang Dai, Bo Zheng, Shusong Wang

“…It is important to explore whether the fourth day morulae could be a widely used alternative transplantation option to replace the fifth day blastocysts. Methods: This study involved 1167 patients undergoing their first in in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) cycles. …”
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The Circular Kitchen by Bas Jansen

“…Economic viability is crucial for feasibility, thus an life cycle costing (LCC) method is developed. Research goal 1 (RG1) is therefore to develop an LCC method that determines the economic performance of circular building components. …”
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Investigating the relationship between the monetary policy shock through the exchange rate channel on the management quality index in the banking system: by examining the productiv... by Farhad Sharifi Bagha, Jafar Haqiqat, Zahra Karimi Takanloo

“…The adoption of monetary policies is the process by which the central bank or the country's monetary authority controls the supply of money or other monetary variables and imposes fluctuations on the economy as a type of economic policies.…”
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Management and Operation Transformation of Urban Park Green Spaces from the Perspectives of Public Goods Provision and Fiscal Sustainability by Peiyi JIA

“…While historical reliance on state control ensured public service provision, it also entrenched inefficiency and fiscal dependency. …”
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Ivacaftor–tezacaftor–elexacaftor, tezacaftor–ivacaftor and lumacaftor–ivacaftor for treating cystic fibrosis: a systematic review and economic evaluation by Steven J Edwards, Benjamin G Farrar, Kate Ennis, Nicole Downes, Victoria Wakefield, Isaac Mackenzie, Archie Walters, Tracey Jhita

“…Objectives To appraise the clinical effectiveness and cost-effectiveness of elexacaftor–tezacaftor–ivacaftor, tezacaftor–ivacaftor and lumacaftor–ivacaftor within their expected marketing authorisations for treating people with cystic fibrosis and at least one F508del mutation, compared with each other and with established clinical management before these treatments. Methods A de novo systematic literature review (search date February 2023) was conducted searching electronic databases (MEDLINE, EMBASE, Cochrane Central Register of Controlled Trials), bibliographies of relevant systematic literature reviews, clinical trial registers, recent conferences and evidence provided by Vertex Pharmaceuticals (Boston, MA, USA). …”
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CREATING THE KULTUK POLYGON FOR EARTHQUAKE PREDICTION: VARIATIONS OF (234U/238U) AND 87SR/86SR IN GROUNDWATER FROM ACTIVE FAULTS AT THE WESTERN SHORE OF LAKE BAIKAL by S. V. Rasskazov, E. P. Chebykin, A. M. Ilyasova, E. N. Vodneva, I. S. Chuvashova, S. A. Bornyakov, A. K. Seminsky, S. V. Snopkov, V. V. Chechel'nitsky, N. A. Gileva

“…In 1970s and 1980s, only quite laborious methods were available for measuring uranium isotopic ratios. …”
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Evaluation of peripheral enthesitis in spondyloarthritis: Ultrasonography versus clinical examination by Anupam Wakhlu, Saumya Ranjan Tripathy, Archana Wakhlu, Durgesh Srivastava, Rasmi Ranjan Sahoo

“…The present study aimed to find the prevalence and pattern of entheseal involvement assessed clinically and by USG. Methods: Fifty-two spondyloarthritis, 26 rheumatoid arthritis, and 26 healthy controls were evaluated for enthesitis by clinical examination and by USG using 2014 OMERACT consensus group definitions at bilateral Achilles insertion on the calcaneus, plantar fascia attachment on the calcaneus, quadriceps tendon insertion on the patella, patellar tendon origin from the inferior pole of the patella, and patellar tendon insertion on the tibial tuberosity. …”
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HEALTH STATUS AND DEMOGRAPHIC PROCESSES OF THE POPULATION OF THE REPUBLIC OF TYVA AT THE BEGINNING OF THE XXI CENTURY by Людмила Салчаковна Эрдыниева

“…The purpose of the study is to assess the state of health and demographic processes in the Republic of Tyva at the beginning of the XXI century. Materials and methods. The paper uses analytical and statistical research methods, including component analysis and T. …”
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Cisplatin or not in advanced gastric cancer: a systematic review and meta-analysis. by Fausto Petrelli, Alberto Zaniboni, Andrea Coinu, Mary Cabiddu, Mara Ghilardi, Giovanni Sgroi, Sandro Barni

“…The purpose of this meta-analysis study was to compare the efficacy of chemotherapy with and without cisplatin in patients with advanced GC.<h4>Methods</h4>Randomised trials that compared first-line cisplatin-based chemotherapy with regimens in which cisplatin was replaced by other agents were identified by electronic searches of PubMed, EMBASE, the Web of Science, and the Cochrane Central Register of Controlled Trials. …”
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TROV - A Model and Vocabulary for Describing Transparent Research Objects by Meng Li, Timothy McPhillips, Craig Willis, Nikolaus Parulian, Bertram Ludäscher, Kacper Kowalik, Lars Vilhuber, Thu-Mai Lewis, Mandy Gooch

“…The Transparent Research Object Vocabulary (TROV) is a key element of the Transparency Certified (TRACE) approach to ensuring research trustworthiness. In contrast with methods that entail repeating computations in part or in full to verify that the descriptions of methods included in a publication are sufficient to reproduce reported results, the TRACE approach depends on a controlled computing environment termed a Transparent Research System (TRS) to guarantee that accurate, sufficiently complete, and otherwise trustworthy records are captured when results are obtained in the first place. …”
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