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Combined genome and transcriptome analysis identifies molecular signatures of aortic disease in patients with Marfan syndrome
Published 2025-09-01“…Smooth muscle cells (SMCs) were cultured directly from the proximal aortic tissues of MFS cases undergoing aortic root replacement and controls during heart transplant. Genome sequencing (GS) analysis was combined with mRNA-sequencing (mRNA-seq) and single-cell gene expression profiling of SMCs. …”
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1522
A phase 3 study of ravulizumab to protect patients with chronic kidney disease from cardiac surgery-associated acute kidney injury and major adverse kidney events (ARTEMIS)
Published 2025-05-01“…The ARTEMIS (RAvulizumab to PRotect PaTients with Chronic Kidney DisEase froM CSA-AKI and Subsequent Major Adverse Kidney Events) trial will assess the efficacy and safety of ravulizumab (a complement C5 inhibitor) in reducing the risk of major adverse kidney events (MAKE) in patients with preoperative CKD undergoing non-emergent cardiac surgery with CPB. Methods This trial is currently recruiting patients with CKD who have planned cardiac surgery requiring CPB including coronary artery bypass grafting, valve replacement or repair, or combined procedures. …”
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1523
Importance of D-dimmer testing in ambulatory detection of atypical and 'silent' phlebothrombosis
Published 2010-01-01“…The patients were randomly divided into the control and DD group. In the control group (629 patients) only US examination of lower limbs deep vein was done. …”
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1524
Effects of Prehabilitation With Advanced Technologies in Patients With Musculoskeletal Diseases Waiting for Surgery: Systematic Review and Meta-Analysis
Published 2024-12-01“…ObjectiveWe aim to evaluate the effects of prehabilitation delivered with advanced technologies on clinically relevant outcomes among patients affected by musculoskeletal diseases and waiting for surgery. MethodsWe searched the PubMed, EMBASE, Cochrane Library, PEDro, and CINAHL databases up to February 2, 2023. …”
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1525
Effects of single femoral nerve block and continuous femoral nerve block on perioperative analgesia and muscle strength in elderly patients undergoing total knee arthroplasty, a ra...
Published 2025-06-01“…ObjectiveTo investigate the effect of single femoral nerve block (SFNB) with 0.2% ropivacaine 50 ml on postoperative pain and muscle strength in elderly patients undergoing knee replacement.MethodsNinety-four patients scheduled for primary total knee arthroplasty (TKA) were randomized into two groups. …”
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1526
Evaluation of Laboratory Toxicities and Field Application of Plant Spray Oil and Its Mixture with <i>Metarhizium anisopliae</i> Against <i>Diaphorina citri Kuwayama</i> (Hemiptera:...
Published 2025-06-01“…Its efficacy further increased to 96.28% by the 8th day, demonstrating its potential to replace chemical control methods. This study provides a practical example for exploring biopesticides and leveraging the synergistic effects of biogenic pesticides in preventing and controlling pests.…”
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1527
The effect of combined training program on clinical competence and professional commitment of perioperative nursing students in laparoscopic surgery: a quasi-experimental study
Published 2025-06-01“…Methods A quasi-experimental pre-test-post-test control group design was employed. …”
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1528
The effect of active learning on academic performance in a Norwegian primary school setting–the Health Oriented Pedagogical Project (HOPP)
Published 2025-07-01“…Active learning, partially replacing traditional classroom methods with physical tasks, yielded significant academic benefits. …”
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1529
Study on the evolution mechanism of mechanical properties of recycled concrete excited by different alkali content at high temperature
Published 2025-04-01“…IntroductionAt present, the gradual reduction of sand and gravel stock is very unfavorable to the preparation of recycled concrete.MethodsTherefore, this study focused on alkali excited recycled concrete with different dosage of copper slag, and set different high temperature methods to test its mechanical properties.ResultsThe results showed that: 1) The residual compressive strength of the control group was not as good as that of the experimental group under other high temperature effects except for the experimental group under 400°C; 2) After high temperature action at 200°C, the ratios of A30, B30 and C30 relative to normal temperature are 1.07, 1.11 and 1.12 respectively, which are slightly higher than those after high temperature action at 400°C, indicating that the use of a certain amount of copper slag to replace fine aggregate quartz sand is helpful to improve the performance of alkali-stimulated recycled concrete at high temperature; 3) The flexural strength of A30 and A60 was 1.410 times and 1.371 times that of the control group after high temperature reaction at 800°C, indicating that the addition of copper slag had a positive impact on the flexural strength of alkali stimulated recycled concrete. 4) After treatment at 200°C, the bending strength ratios of control groups, A30, A60 and A100 were 0.676, 0.748, 0.728 and 0.687, respectively, while after treatment at 600°C, the corresponding ratios were 0.349, 0.440, 0.437 and 0.382, respectively, indicating that the addition of copper slag in high temperature environment, the bending strength ratio of control groups was 0.676, 0.748, 0.728 and 0.687, respectively.DiscussionIt can improve the flexural strength of alkali excited recycled concrete. …”
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1530
Bonne nature, mauvais artifice ? L’Église catholique et l’écologie : retour sur Laudato Si’
Published 2017-12-01“…It observes that suspicion toward artificial methods and preference given to natural methods has become during the 20th century one of the main distinctions in the Catholic Church’s position regarding birth control. …”
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1531
Evaluation of Retention and Fracture Strength of All Ceramic Crowns with Three Different Esthetic Cast Post–Core Systems
Published 2023-01-01“…There were no discernible distinctions among the three study methods regarding fracture strength. Nonetheless, the retention strength of the IPS group resembled that of the control group, surpassing that of the composite and ceramic groups.…”
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1532
Effects of Optimized Fertilization and Organic Fertilizer Subsitution Technology on the Growth and Soil Fertility of Chinese Flowering Cabbage
Published 2024-10-01“…Field plot tests were conducted and seven treatments were set: the control (CK), customary fertilization (T1), optimized fertilization (T2), optimized fertilization + 15% organic fertilizer replacing N (T3), optimized fertilization + 30% organic fertilizer replacing N (T4), optimized fertilization + 15% biochar-based organic fertilizer replacing N (T5), and optimized fertilization + 30% biochar-based organic fertilizer replacing N (T6). …”
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1533
Anchored and epoxied ferrocement strips for improving flexural performance of two-way reinforced concrete slabs
Published 2025-07-01“…The research explores the effectiveness of various strip configurations, including orthogonal and diagonal arrangements, bonded with either epoxy alone or epoxy combined with steel anchors. By replacing a portion of the slab's concrete cover with ferrocement strips, this method aims to enhance the load-carrying capacity, ductility, and crack resistance of the slabs while optimizing material usage and minimizing additional weight. …”
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1534
Immunological and pathobiological characteristics of a novel live Salmonella Typhimurium-vectored Campylobacter vaccine candidate for layer chickens
Published 2025-03-01“…Although autogenous vaccines are in use in some countries with limited efficacy, no vaccine is currently licensed for widespread use.MethodsThis study developed and characterized a live Salmonella Typhimurium vector strain designed to deliver the conserved Campylobacter N-glycan heptasaccharide as a target antigen against C. hepaticus.ResultsThe replacement of the S. …”
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1535
Comparative drug release kinetics of Terminalia arjuna mediated SeNPs NanoGel and ZnONPs NanoGel – An in-vitro study
Published 2025-01-01“…The sustained release profiles of both formulations suggest effective control over drug release, maintaining therapeutic drug levels over an extended period. …”
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Three simple and cost-effective assays for AAC(6′)-Ib-cr enzyme activity
Published 2025-04-01“…In a word, this study presented three simple, efficient, and cost-effective methods for detecting APE, suitable for clinical microbiology laboratories under various conditions for the prevention and control of hospital infections.…”
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1538
The Growth-Inhibitory Effect of Glass Ionomer Liners Reinforced with Fluoride-Modified Nanotubes
Published 2025-06-01“…The aim of this research was to compare the growth-inhibitory effect of halloysite-based nanotubes preloaded with sodium fluoride incorporated into two commercial glass ionomers (Vitrebond 3M<sup>TM</sup> and Ionobond VOCO) for indirect pulp capping. Methods: Sixty samples were prepared and were distributed into two control groups, two positive control groups and two experimental groups. …”
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1539
Crisis conformity as affiliation defense under mortality salience: a TMT perspective
Published 2025-07-01“…Study 1b used an improved TMT paradigm, replacing neutral controls with economic crisis manipulations to isolate existential threats from nonspecific emotional arousal. …”
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1540
The development and application of mini-barcodes from mitochondrial DNA for identifying medicinal leeches from traditional medicines
Published 2025-07-01“…Mislabeled species have been uncovered in proprietary Chinese medicine, notably the claimed Hirudo nipponia, which was replaced by W. pigra. The results highlight the value of mini-barcodes in enhancing product quality control and offer a reliable method for accurate species identification in traditional and commercial leech-based medicines. …”
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