Forecasting framework for dominant SARS-CoV-2 strains before clade replacement using phylogeny-informed genetic distances by Kyuyoung Lee, Atanas V. Demirev, Sangyi Lee, Seunghye Cho, Hyunbeen Kim, Junhyung Cho, Jeong-Sun Yang, Kyung-Chang Kim, Joo-Yeon Lee, Woojin Shin, Soyoung Lee, Sejik Park, Philippe Lemey, Man-Seong Park, Man-Seong Park, Man-Seong Park, Jin Il Kim, Jin Il Kim, Jin Il Kim

“…Furthermore, we introduced a forecasting framework to estimate the potential of emerging variants leading to clade replacement by analyzing non-synonymous and synonymous genetic distances from clade roots, which reflect global herd immune pressure.MethodsNon-synonymous and synonymous genetic distances from both Wuhan and clade root strains were assessed to predict whether a clade would become dominant or extinct within 3 months before the clade replacement.ResultsThrough five observed clade replacements up to January 2024, we captured the quantifiable heterogeneity in non-synonymous and synonymous genetic distances of the S gene from clade roots between dominant and extinct variants, as measured by the extent of novelty, whether through gradual or drastic change.DiscussionOur framework demonstrated high predictability for identifying the next clade root before replacement in both training and test datasets (area under the receiver operating characteristic curve [AUROC] > 0.90) by incorporating differential weighting of non-synonymous and synonymous genetic distances. …”
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Mortality after transcatheter aortic valve replacement in young multimorbid patients as compared to an age-, gender- and comorbidity-matched background population by Pernille Steen Bække, Vilhelmas Bajoras, Vilhelmas Bajoras, Vilhelmas Bajoras, Jawad Butt, Thomas Pilgrim, Nicholas Joseph Montarello, Maurizio Taramasso, Didier Tchetche, Liesbeth Rosseel, Ričardas Kundelis, Ričardas Kundelis, Kristijonas Česas, Alexander Sedaghat, Jan-Malte Sinning, Rik Adrichem, Mizuki Miura, Magdalena Erlebach, Stephan Windecker, Darren Mylotte, Raj Makkar, Emil Fosbøl, Nicolas Van Mieghem, Ole De Backer

“…IntroductionContrary to the current guidelines patients with symptomatic severe aortic stenosis and ≤65 years of age are often referred for transcatheter aortic valve replacement (TAVR). However, the outcome after TAVR in this patient cohort remains unclear.ObjectivesThis study aimed to assess the rationale for denial of surgical aortic valve replacement (SAVR) in young multimorbid patients referred for TAVR, to evaluate 3-year all-cause mortality and to compare outcomes with a matched control cohort.Patients and methodsRetrospective data were collected on all consecutive patients ≤65 years of age with severe aortic stenosis treated with TAVR at 9 centres between 2010 and 2019. …”
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Distributed Control Strategy for Automatic Power Sharing of Hybrid Energy Storage Systems with Constant Power Loads in DC Microgrids by Tian Xia, He Zhou, Bonan Huang

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Incidence of Coronary Obstruction During Aortic Valve Implantation: Meta-Analysis and Mixt-Treatment Comparison of Self-Expandable Versus Balloon-Expandable Valve Prostheses by Yu Fei Wang, Zai Qiang Liu, Xiao Teng Ma, Li Xia Yang, Zhi Jian Wang, Yu Jie Zhou

“…Background: Recently, the transcatheter aortic valve replacement (TAVR) indications have expanded; meanwhile, valve systems have continuously evolved and improved. …”
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Active power filter control strategy based on repetitive quasi-proportional resonant control with linear active disturbance rejection control. by Yifei Gao, Liancheng Zhu, Xiaoyang Wang, Hongshi Wei, Xiaoguo Lv

“…Thus, in this paper, a repetitive quasi-proportional resonant (QPR) with linear active disturbance rejection control (LADRC) is proposed. Firstly, QPR control is introduced to replace PI control. …”
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Reduction of the Electrical Resistance of Grounding Devices by the Use of a Soil Replacement Mixture Based on Graphite and Hydrogel to Stabilize the Electrophysical Parameters of t... by I. A. Pavlovich, S. M. Baraishuk

“…Therefore, the paper also considers other ways to reduce the resistance of the ground loop; in particular, the authors propose a method for reducing the resistance of a grounding device based on the method of partial replacing the soil in the near-electrode region with a mixture with a lower resistivity capable of collecting moisture based on graphite and hydrogel. …”
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The pre- and post-COVID-19 pandemic dengue fever patterns in southeastern coastal China in 2019 and 2024: molecular evolution and strain replacement by Tianran Zhang, Yaqi Shi, Leyi Zhang, Jian Wang, Chengchao Yu, Binbin Lv, Sisi Wu, Yiru Huang, Xuewei Liu, Hupiao Dai, Mingshi Zhou, Yanjuan Liao, Wei Wang, Guankai Lin

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Research on digital valve-controlled hydraulic system for active radial control of wheelsets by NI Wenbo, LIU Shuwei, WANG Xuemei

“…This approach mitigates heat generation at its source by replacing the servo valve control with high-speed on/off valve-based PCM control, with a focus on the main contributing elements. …”
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Tailored surgical strategies for mini-access open total arch repairCentral MessagePerspective by Soo Jin Park, MD, PhD, Hong Rae Kim, MD, PhD, Ho Jin Kim, MD, Joon Bum Kim, MD, PhD

“…To evaluate comparative outcomes, contemporary cases undergoing total arch replacement via sternotomy with similar eligibility criteria served as a control group, and the inverse-treatment-weighting method was used to adjust for baseline characteristics. …”
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En bloc excision and customized prosthesis replacement for Campanacci III giant cell tumours of the distal radius: five cases report and a review of the literature by Ningjun Wan, Zhen Wang, Shaowei Xu, Bin Hao

“…En bloc resection of Campanacci grade III giant cell tumours of the distal radius has been promoted as a reliable method for achieving local control, associated with the dual problem of bone defect reconstruction and functional recovery. …”
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Can virtual reality replace conventional vestibular rehabilitation tools in multisensory balance exercises for vestibular disorders? A non-inferiority study by Gaël Le Perf, Guillaume Thebault, Claire Duflos, Fanchon Herman, Sylvie Cauquil-Gleizes, Isabelle Laffont

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Urea-ka: replacing inorganic nitrogen fertilizer with Azolla pinnata maintains rice yields with reduced input costs in the Senegal River Valley by Xorla S. Ocloo, Moussa Mbaye, Abou Sy Dit Tid Mouline Counta, Gonzalo M. Vazquez-Prokopec, Nicolas Jouanard, Momy Seck, Silvain Leonard Thierry Sow, David J. Civitello

“…We assessed the feasibility of Azolla-rice intercropping in Saint-Louis, Senegal using a mixed-methods approach. We conducted interviews with farmers to assess their perceptions of Azolla-rice farming while they participated in an experiment to compare rice yields among four treatments: control plots (the existing practices of the farmer), Azolla plots (existing practices and adding fresh Azolla), low input plots (a 50% reduction of urea), and low input + Azolla plots (reduced urea + Azolla) in farmers’ paddies located in the Senegal River Valley. …”
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Growth performance and carcass traits of growing and finishing pigs fed diets with a partial to total replacement of soybean meal with Spirulina powder by Gregorio Don, Diana Giannuzzi, Alessandro Toscano, Stefano Schiavon, Luigi Gallo

“…Methods Eighty-eight pigs, gilts and barrows mixed together, with initial body weight of 52.4 ± 4.2 kg, were allotted into 4 isoenergetic, isoproteic, and isoaminoacidic dietary treatments, which included a conventional control diet based on cereals and soybean meal and one of 3 diets formulated by replacing nearly 33%, 66% or 100% soybean with Spirulina. …”
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Midterm outcomes of Bentall procedure versus isolated aortic valve replacement for bicuspid aortic valve with severe stenosis and ascending aortic dilation by LI Shijie, LI Tianbo, YANG Zhipeng

“…Methods‍　‍A retrospective cohort study was conducted on 96 eligible patients who underwent surgical treatment in our institute between January 2018 and December 2022. …”
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Increased levels of inflammatory markers and carotid intima-media thickness in asymptomatic patients with Sheehan syndrome without growth hormone replacement therapy by Shahnaz Ahmad Mir, Asif Ahmad Naik, Basharat Dar, Hardeep Singh, Bashir Ahmad Laway, Ahila Ashraf, Naseer Ahmad Khan

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Fabry Cardiomyopathy: Myocardial Fibrosis, Inflammation, and Down‐Regulation of Mannose‐6‐Phosphate Receptors Cause Low Accessibility to Enzyme Replacement Therapy by Andrea Frustaci, Romina Verardo, Michele Magnocavallo, Emanuela Frustaci, Matteo Antonio Russo, Cristina Chimenti

“…The pathologic mechanisms involved are still unclear. Methods and Results Ten male patients with advanced Fabry disease cardiomyopathy on enzyme replacement therapy, whose disease progressed from maximal wall thickness of 15.4±2.2 to 19.3±2.1 mm in 8.6±1.4 years of follow‐up, underwent left ventricular endomyocardial biopsy before and 4 hours after β‐agalsidase infusion (1 mg/kg). …”
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The efficacy of enhanced recovery program compared to routine care for patients undergoing knee replacement surgery: a systematic review and meta-analysis by Yanyan Ju, Guangling Wang, Xinglei Xiao

“…Abstract Objectives This meta-analysis compared enhanced recovery program with routine care for patients undergoing knee replacement surgery. Methods PubMed, Scopus, Web of Science, and the Cochrane Library, were systematically searched up to December 20, 2024, to identify randomized controlled trials comparing the effects of enhanced recovery with routine care on the outcomes of patients undergoing total knee replacement. …”
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Cytisine Use Vs Nicotine Replacement Therapy in Relapsed Smokers with Heart Disease: Feasibility Results from a Pilot Randomized Trial by Hassan Mir, MD, MHI, MPH, FRCPC, FACP, Kerri-Anne Mullen, PhD, Javad Heshmati, PhD, Ashley Baldwin, BAHsc, Evyanne Quirouette, BSc, Emilie Serano, RN, MN, Mustafa Coja, BPHE, BA, Andrew L. Pipe, MD, Robert D. Reid, PhD

“…We plan to investigate whether cytisine use is effective for relapse recovery and conducted a pilot randomized trial to assess the feasibility of a definitive trial. Methods: A 2-group, single-site pilot randomized controlled trial was conducted. …”
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Comparison between Combination of Proximal Adductor Canal Block and Infiltration between Popliteal Artery and Capsule of Knee (iPACK) with Large-Volume Distal Adductor Canal Block... by Pryambodho Pryambodho, Lawrence Kwan, Aida Rosita Tantri, Andri Maruli Tua Lubis

“…Background: Adductor canal block (ACB) and infiltration between popliteal artery and capsule of knee (iPACK) are popular block methods for analgesia after total knee replacement (TKR), covering both the anterior and posterior knee. …”
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The Use of Perceval Valves in Older Patients: A Systematic Review by Ivo Deblier, Dina De Bock, Inez Rodrigus, Wilhelm Mistiaen

“…Results: A total of six propensity score-matched series and four randomized controlled trials were identified after removing articles with data from the same patient population. …”
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