Evaluating long-term outcomes and the impact of small aortic annulus on valve replacement—a novel systematic review and meta-analysis comparing surgery vs. transcatheter interventi... by Aamir Amin, Cara Mohammed, Sten Kajitani, Khalid AlMashari, Rajanikant Kumar, Alifa Sabir, Paulina Briz-Echeverria, Shiva Mokhtassi, Shashi Kumar Kallikere Lakshmana, Ahmed Bokhari, Muhammad Ehsan, Hasan Ahmad, Raheel Ahmed, Toufan Bahrami

“…SAVR in aortic stenosis patients, as well as their respective impact on patients with small aortic annulus (SAA).MethodsMEDLINE, Embase, Cochrane Library, and ClinicalTrials.gov were searched for randomized controlled trials (RCTs) and comparative observational studies on TAVI vs. …”
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COMPARATIVE STUDY BETWEEN ATK 1a WITH CONSTRICTED POLYETHYLENE VERSUS POSTERO-STABILIZED by Fabiana Alves Costa Menegassi, Guilherme Blois Vasconcelos Pereira, Gabriel Alves Freitas, Rodrigo Balieiro, Sandra Tie Nishibe Minamoto, Alan de Paula Mozella, Rodrigo Sattamini Pires e Albuquerque

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Comparative Analysis of Multidisciplinary Complementary Intervention Versus Routine Physiotherapy Rehabilitation to Reduce Kinesiophobia in Patients with Knee Osteoarthritis Underg... by Hung Tzu-Han, Liu Mei-Chun, Kuo Ya-Wen, Lee Jiann-Der

“…The aim of this systematic review was to compare the effectiveness of multidisciplinary care intervention with that of conventional physical therapy in mitigating kinesiophobia in patients with knee osteoarthritis undergoing joint replacement. Methods This study was registered with the International Prospective Register of Systematic Reviews (registration no. …”
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Synthesis of calcium phosphate particles via the solution combustion method and investigation of the effects of initial pH and heat treatment temperature on the physical and biolog... by Neda Sami, Sahar Mollazadeh Beidokhti, Jalil Vahdati Khaki

“…Fluoroapatite is one of the materials that can release F- ions at a controlled rate. Fluoride ion replacement improves cell proliferation and activation of osteogenic cells to the implant surface.…”
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Comprehensive and robust stability-indicating reversed phase high performance liquid chromatography (RP-HPLC) method for Rivaroxaban: synergistic integration of infrared spectrosco... by Aktham Mestareehi, Aktham Mestareehi, Aktham Mestareehi

“…This stability-indicating method is highly suitable for routine quality control and analytical applications in both raw materials and finished drug products, owing to its simplicity, efficiency, and robustness.…”
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Generalizability of motor modules across walking-based and in-place tasks – a distribution-based analysis on total knee replacement patients by Mahziyar Darvishi, Sajjad Daroudi, Shahabedin Tavasoli, Ali Shafiezadeh, Farzam Farahmand

“…It was concluded that there are shared motor modules across walking-based and in-place tasks in TKR individuals, with their generalizability and representability depending upon the analysis method. This finding highlights the importance of the analysis method in identifying the shared motor modules, as the main building blocks of motor control.…”
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The Effect of Serish Root Gum (Eremurus luteus) as Fat Replacer on Rheological, Physical and Sensory Properties of Low Fat Ice Cream by Fatemeh Sabzmeidani, Masoud Taghizadeh, Mohammad Saleh Hemati Hasan Poor

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Effect of volume replacement during combined experimental hemorrhagic shock and traumatic brain injury in prostanoids, brain pathology and pupil status by Fernando Campos Gomes Pinto, Matheus Fernandes de Oliveira, Ricardo Prist, Maurício Rocha e Silva, Luiz Fernando Ferraz da Silva, Antonio Capone Neto

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Effect of graft sizing in valve-sparing aortic root replacement for bicuspid aortic valve: The Goldilocks ratioCentral MessagePerspective by Perry S. Choi, MD, Amit Sharir, BA, Yoshikazu Ono, MD, Masafumi Shibata, MD, Alexander D. Kaiser, PhD, Yuanjia Zhu, MD, PhD, Alison L. Marsden, PhD, Y. Joseph Woo, MD, Michael R. Ma, MD, Joon Bum Kim, MD, PhD

“…Objective: To investigate the effect of graft sizing on valve performance in valve-sparing aortic root replacement for bicuspid aortic valve. Methods: In addition to a diseased control model, 3 representative groups—free-edge length to aortic/graft diameter (FELAD) ratio <1.3, 1.5 to 1.64, and >1.7—were replicated in explanted porcine aortic roots (n = 3) using straight grafts sized respective to the native free-edge length. …”
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Improving nerve and muscle function: an exploration of targeted nerve function replacement following differential delay periods in a rat model by Chunxiao Tang, Yuanheng Li, Xinxian Fan, Jiamei Guo, Yifeng Lin, Yifan Gao, Lin Yang

“…This study evaluates TNFR efficacy in restoring denervated muscle function across different postoperative intervals in a rat model. Methods Thirty Sprague–Dawley rats (220–250 g) were divided into five equal groups (n = 6 per group): control (no transection), denervated (transection without repair), immediate TNFR after median nerve transection, 2-week delayed TNFR, and 4-week delayed TNFR. …”
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The effect of hormone replacement therapy on cervical cancer risk in perimenopausal women: a systematic review and meta-analysis of observational studies by Yingna Zhou, Jie Wei, Youqin Ruan

“…BackgroundHormone replacement therapy (HRT) alleviates menopausal symptoms in perimenopausal women and help improve their quality of life, but its increased risk of cervical cancer (CC) remains to be evaluated.MethodsA system review and meta-analysis was conducted to retrieve literature related to HRT and CC risk by searching Pubmed, Embase, Science Direct, Web of Science, and Google Scholar databases. …”
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Manual Dilution of Continuous Renal Replacement Therapy Fluids in Anuric Patients with Severe Hyponatremia: A Case Report and Systematic Review by Mark V. Koning, Lassima Reijnen, Femy Kemperman, Eugenie Schipper-Reintjes

“…Manual dilution of the fluids during continuous renal replacement therapy (CRRT) is a method that can lead to a controlled correction of sodium. …”
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Verification Technical Scheme for Deep Learning Algorithm Based on Interactive Zero Knowledge Protocol by LYU Yanfeng, LYU Xuesheng, HUANG Shenghui, LIANG Qinglei

“…Although there are corresponding military control verification methods now, the shielding methods for sensitive information are still not perfect. …”
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Single-nucleus RNA sequencing reveals the specific molecular signatures of myeloid cells responding to brain injury after microglial replacement by Xiao-Yi Xiong, Xiao-Yi Xiong, Xiao-Yi Xiong, Haicheng Yuan, Ying Mu, Yi He, Fang Xie, Xiao-Shuang Feng, Jia-Xin Xie, Xin-Ru Pan, Yu-Fei Wang, Jian Gong, Xiaoming Zheng, Peng-Fei Wang

“…BackgroundMyeloid cells, such as resident microglia (MG), infiltrating monocytes (Mo), macrophages (MΦ), and CNS border-associated macrophages (BAM) in the brain, participate in aged brain injury. Aged microglial replacement is protective against brain injury in aged mice; however, whether/how the molecular changes in myeloid cells are affected by this replacement in injured brains remains unclear.MethodsAged microglia in mice were eliminated by PLX3397 for 21 consecutive days and repopulated following withdrawal for 21 days; then, intracerebral hemorrhage (ICH) models were constructed. …”
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Forecasting framework for dominant SARS-CoV-2 strains before clade replacement using phylogeny-informed genetic distances by Kyuyoung Lee, Atanas V. Demirev, Sangyi Lee, Seunghye Cho, Hyunbeen Kim, Junhyung Cho, Jeong-Sun Yang, Kyung-Chang Kim, Joo-Yeon Lee, Woojin Shin, Soyoung Lee, Sejik Park, Philippe Lemey, Man-Seong Park, Man-Seong Park, Man-Seong Park, Jin Il Kim, Jin Il Kim, Jin Il Kim

“…Furthermore, we introduced a forecasting framework to estimate the potential of emerging variants leading to clade replacement by analyzing non-synonymous and synonymous genetic distances from clade roots, which reflect global herd immune pressure.MethodsNon-synonymous and synonymous genetic distances from both Wuhan and clade root strains were assessed to predict whether a clade would become dominant or extinct within 3 months before the clade replacement.ResultsThrough five observed clade replacements up to January 2024, we captured the quantifiable heterogeneity in non-synonymous and synonymous genetic distances of the S gene from clade roots between dominant and extinct variants, as measured by the extent of novelty, whether through gradual or drastic change.DiscussionOur framework demonstrated high predictability for identifying the next clade root before replacement in both training and test datasets (area under the receiver operating characteristic curve [AUROC] &gt; 0.90) by incorporating differential weighting of non-synonymous and synonymous genetic distances. …”
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Mortality after transcatheter aortic valve replacement in young multimorbid patients as compared to an age-, gender- and comorbidity-matched background population by Pernille Steen Bække, Vilhelmas Bajoras, Vilhelmas Bajoras, Vilhelmas Bajoras, Jawad Butt, Thomas Pilgrim, Nicholas Joseph Montarello, Maurizio Taramasso, Didier Tchetche, Liesbeth Rosseel, Ričardas Kundelis, Ričardas Kundelis, Kristijonas Česas, Alexander Sedaghat, Jan-Malte Sinning, Rik Adrichem, Mizuki Miura, Magdalena Erlebach, Stephan Windecker, Darren Mylotte, Raj Makkar, Emil Fosbøl, Nicolas Van Mieghem, Ole De Backer

“…IntroductionContrary to the current guidelines patients with symptomatic severe aortic stenosis and ≤65 years of age are often referred for transcatheter aortic valve replacement (TAVR). However, the outcome after TAVR in this patient cohort remains unclear.ObjectivesThis study aimed to assess the rationale for denial of surgical aortic valve replacement (SAVR) in young multimorbid patients referred for TAVR, to evaluate 3-year all-cause mortality and to compare outcomes with a matched control cohort.Patients and methodsRetrospective data were collected on all consecutive patients ≤65 years of age with severe aortic stenosis treated with TAVR at 9 centres between 2010 and 2019. …”
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Incidence of Coronary Obstruction During Aortic Valve Implantation: Meta-Analysis and Mixt-Treatment Comparison of Self-Expandable Versus Balloon-Expandable Valve Prostheses by Yu Fei Wang, Zai Qiang Liu, Xiao Teng Ma, Li Xia Yang, Zhi Jian Wang, Yu Jie Zhou

“…Background: Recently, the transcatheter aortic valve replacement (TAVR) indications have expanded; meanwhile, valve systems have continuously evolved and improved. …”
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Active power filter control strategy based on repetitive quasi-proportional resonant control with linear active disturbance rejection control. by Yifei Gao, Liancheng Zhu, Xiaoyang Wang, Hongshi Wei, Xiaoguo Lv

“…Thus, in this paper, a repetitive quasi-proportional resonant (QPR) with linear active disturbance rejection control (LADRC) is proposed. Firstly, QPR control is introduced to replace PI control. …”
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Enhanced cancer cell sorting using lab-on-a-disk pattern design with magnetic and centrifugal forces by Bill Cheng, Wei-Cheng Chao, Yi-Han Chen, Yao-Tsung Lin

“…Using microfluidic flow for biological detection is a non-invasive method that can replace traditional invasive testing methods to achieve fast and accurate results. …”
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Early Sweet Potato Plant Detection Method Based on YOLOv8s (ESPPD-YOLO): A Model for Early Sweet Potato Plant Detection in a Complex Field Environment by Kang Xu, Wenbin Sun, Dongquan Chen, Yiren Qing, Jiejie Xing, Ranbing Yang

“…Traditional methods of pest control for sweet potatoes cause the waste of pesticides and land pollution, but the target detection algorithm based on deep learning can control the precise spraying of pesticides on sweet potato plants and prevent most pesticides from entering the land. …”
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