An observational study of haemophilia A patients without inhibitors using the French national claims (SNDS) database by Marc Trossaërt, Aletta Falk, Laurène Gautier, Nana Kragh, Olivia Van Hinloopen, Remi Varin

“…Objectives: To describe clinical characteristics, factor consumption, and events of interest in patients with haemophilia A without inhibitors receiving prophylaxis in France, and the clinical impact of switching to Elocta® in this population.Methods: This retrospective, observational study using the Système National des Données de Santé database, analysed data from patients with haemophilia A without inhibitors using prophylactic factor VIII (FVIII) replacement therapy during 2016–2019. Clinical characteristics, treatment patterns and switches, factor consumption, and rate of events of interest were determined. …”
Get full text

Bronchopulmonary Dysplasia in Post-Surfactant Era: Results of an Objective Assessment of the Disease by I. V. Davydova, A. V. Anikin, O. V. Kustova, A. V. Sidenko, E. Yu. Basargina, E. V. Pavlyukova, V. K. Pozharishchenskaya

“…In this connection, an objective assessment of the efficacy of surfactant replacement therapy is required. The article presents the results of studying the patterns of development of bronchopulmonary dysplasia in premature infants (n =121) of different gestational age. …”
Get full text

Five-Year Sales Trends of Osteoporosis Medications in Korea: A Market Analysis Based on IMS Health Sales Audit Data (2018–2023) by Jung Yoon Park, Youn-Jee Chung, Mee-Ran Kim, Jae-Yen Song

Get full text

Effect of Irrigation Interval and Corn (Zea mays L.)-Sorghum (Sorghum bicolor L.) Intercropping on the Quantitative and Qualitative Characteristics of Fodder by Saeed Sadeghzadeh Hemayati, Hamed Mansouri, Mohsen Shahsavarpour

Get full text

Does partial replacement of corn with glycerin in beef cattle diets affect in vitro ruminal fermentation, gas production kinetic, and enteric greenhouse gas emissions? by Pedro Del Bianco Benedeti, Mozart Alves Fonseca, Teshome Shenkoru, Marcos Inácio Marcondes, Eduardo Marostegan de Paula, Lorrayny Galoro da Silva, Antonio Pinheiro Faciola

“…Five in vitro experiments were conducted with the following objectives: 1) To evaluate the ruminal fermentation of three different single ingredients: corn, glycerin, and starch (Exp. 1 and 2); 2) To assess effects of partially replacing corn with glycerin in beef cattle diets on ruminal fermentation pattern (Exp. 3 and 4); and 3) To evaluate the effects of glycerin inclusion on the extension of ruminal DM digestibility of feeds with high (orchard hay) and low (corn) fiber content (Exp. 5). …”
Get full text

Risk factors and predictive models for post-operative moderate-to-severe mitral regurgitation following transcatheter aortic valve replacement: a machine learning approach by Zhenzhen Li, Jianing Fan, Jiajun Fan, Jiaxin Miao, Dawei Lin, Jingyan Zhao, Xiaochun Zhang, Wenzhi Pan, Daxin Zhou, Junbo Ge

“…Shapley Additive Explanation (SHAP) values were used to interpret predictive patterns and develop a clinically relevant model. Results Among the evaluated models, the random forest model exhibited the highest predictive performance for post-operative moderate-to-severe MR after TAVR. …”
Get full text

Enhanced antibiotic release and biocompatibility with simultaneous addition of N-acetylcysteine and vancomycin to bone cement: a potential replacement for high-dose antibiotic-load... by Tzu-Hao Tseng, Chih-Hao Chang, Chien-Lin Chen, Hongsen Chiang, Jyh-Horng Wang, Tai-Horng Young

Get full text

Open reduction, internal fixation of Vancouver B1, C & D type periprosthetic femoral fractures with use of an antiglide plate at fracture apex - The “Apex Plate” by Roland Bell, Mohammed Remtulla, Bryan Riemer

“…The complex nature and varied pattern of these injuries requires a range of specialized surgical techniques and tools. …”
Get full text

Rifampin-loaded Mesoporous Silica Nanoparticles Improved Physical and Mechanical Properties and Biological Response of Acrylic Bone Cement by Mohammad Reza Shafiei, Nader Nezafati, Saeed Karbasi, Anousheh Zargar Kharazi

Get full text

Impact of sex and menopausal hormonal therapy on cardiovascular diseases in people with diabetes or prediabetes by Do Kyeong Song, Yeon-Ah Sung, Young Sun Hong, Min-ho Kim, Hyejin Lee

Get full text

Is the treatment of ankle osteoarthritis changing over time in Italy? Analysis of temporal trends for fusion and arthroplasty in a population-based study from 2001 to 2022 on the N... by Adriano Cuccu, Elena Manuela Samaila, Enrico Ciminello, Umberto Alfieri Montrasio, Fabrizio Cortese, Stefania Ceccarelli, Tiziana Falcone, Marina Torre

“…The analysis of the number of procedures performed on inhabitants by region and that performed by all the hospitals in the region showed a different pattern across Italy. Conclusions The substantial increase in TARs may be owing to improved implant designs and innovative surgical technologies, which allow the treatment of more severe cases and deformities, previously untreated or treated by a fusion. …”
Get full text

A Hierarchical Cache Architecture-Oriented Cache Management Scheme for Information-Centric Networking by Yichao Chao, Rui Han

“…This paper proposes a cache management scheme for hierarchical cache architectures in ICN, which introduces a differentiated replica replacement policy to accommodate the varying request access patterns at different cache layers, thereby enhancing overall cache performance. …”
Get full text

Effect of partially replacing crushed oyster shell as fine aggregate on the shear behavior of short RC beams using GFRP rebar strengthened with TRC: Experimental and numerical stud... by Tu Sy-Quan, Nguyen Huy-Cuong, Ngo Dang-Quang

“…The crushed oyster shell (COS) was replaced partially with natural sand in different mixtures. …”
Get full text

Infantile Pompe disease: Clinical picture, diagnosis, and treatment by N. P. Kotlukova, S. V. Mikhailova, T. M. Bukina, E. Yu. Zakharova

“…It is characterized by a progressive pattern and a fatal outcome during the first year of life. …”
Get full text

Muscle MRI / whole-body MRI in diagnosis and dynamic evaluation of neuro-muscular disorders by Robert Carlier

Get full text

Real-world effectiveness of hemodialysis modalities: a retrospective cohort study by Yan Zhang, Anke Winter, Belén Alejos Ferreras, Paola Carioni, Otto Arkossy, Michael Anger, Robert Kossmann, Len A. Usvyat, Stefano Stuard, Franklin W. Maddux

“…Compared with hemodialysis, hemodiafiltration was associated with an adjusted hazard ratio (HR) for all-cause mortality of 0.78 (95% confidence interval [Cl], 0.76–0.80), irrespective of COVID-19 infection. The pattern of a beneficial effect of hemodiafiltration was consistently observed among all analyzed subgroups. …”
Get full text

Gaps in the management of adrenal insufficiency in melanoma survivors: a retrospective cohort studyResearch in context by Wei Lin, Wei Wang, F. Stephen Hodi, Le Min

“…We compared glucocorticoid management patterns, quality of life using distress scores, and the impact of different glucocorticoid types on survival outcomes using Kaplan–Meier analysis. …”
Get full text

Effects of Bacillus subtilis-fermented soybean meal replacing fish meal on antioxidant activity, immunity, endoplasmic reticulum stress and hepatopancreas histology in Pacific whit... by Songming Chen, Jieyu Dai, Yan Chen, Qiang Chen, Fen Dong, Congcong Wang, Yulong Sun, Jiteng Wang, Tao Han

“…Subsequently, we investigated the response patterns of different organs to FSBM substitution from antioxidant, endoplasmic reticulum stress and immunity. …”
Get full text

Building a pre-surgical multiparametric-MRI-based morphologic, qualitative, semiquantitative, first and high-order radiomic predictive treatment response model for undifferentiated... by Raul F. Valenzuela, Elvis Duran-Sierra, Mathew Antony, Behrang Amini, Sam Lo, Keila E. Torres, Robert S. Benjamin, Jingfei Ma, Ken-Pin Hwang, R. Jason Stafford, Dejka Araujo, Andrew J. Bishop, Ravin Ratan, Wei-Lien Wang, Jossue Espinoza, Pia V. Valenzuela, Chengyue Wu, John E. Madewell, William A. Murphy, Colleen M. Costelloe

Get full text

Safeguarding Self-Governance by Connie B. Berthelsen, Kirsten Frederiksen

“…The aim of this study was to generate a grounded theory of older patients’ pattern of behavior in relation to their relatives’ involvement in fast-track programs during total joint replacement. …”
Get full text