Spatially mapping the tumour immune microenvironments of non-small cell lung cancer by Lysanne Desharnais, Mark Sorin, Morteza Rezanejad, Bridget Liu, Elham Karimi, Aline Atallah, Anikka M. Swaby, Miranda W. Yu, Samuel Doré, Saskia Hartner, Benoit Fiset, Yuhong Wei, Baharak Kadang, Roni Rayes, Philippe Joubert, Sophie Camilleri-Broët, Pierre-Olivier Fiset, Daniela F. Quail, Jonathan D. Spicer, Logan A. Walsh

“…Abstract Lung cancer is the leading cause of cancer-related deaths. An enhanced understanding of the immune microenvironments within these tumours may foster more precise and efficient treatment, particularly for immune-targeted therapies. …”
Get full text

Ongoing Dynamics of Peak Alpha Frequency Characterize Hypnotic Induction in Highly Hypnotic-Susceptible Individuals by Mathieu Landry, Jason da Silva Castanheira, Floriane Rousseaux, Pierre Rainville, David Ogez, Karim Jerbi

“…Hypnotic phenomena exhibit significant inter-individual variability, with some individuals consistently demonstrating efficient responses to hypnotic suggestions, while others show limited susceptibility. …”
Get full text

Development of a Genotyping‐in‐Thousands by Sequencing (GT‐Seq) Panel for Identifying Individuals and Estimating Relatedness Among Alaska Black Bears (Ursus americanus) by Eleni L. Petrou, Colette D. Brandt, Timothy J. Spivey, Kristen M. Gruenthal, Cherie M. McKeeman, Sean D. Farley, David Battle, Cory Stantorf, Andrew M. Ramey

“…We empirically validated the GT‐seq panel using samples collected at different spatial scales. These samples included tissues (n = 82) obtained from bears within a small geographic area in Anchorage, Alaska, which were likely to be relatives as well as the hunter‐harvested samples collected from geographically widespread locations throughout Southcentral Alaska. …”
Get full text

Harnessing Hazara Virus as a Surrogate for Crimean–Congo Hemorrhagic Fever Virus Enables Inactivation Studies at a Low Biosafety Level by Judith Olejnik, Kristina Meier, Jarod N. Herrera, Daniel J. DeStasio, Dylan J. Deeney, Elizabeth Y. Flores, Mitchell R. White, Adam J. Hume, Elke Mühlberger

“…Importantly, the parameters of the aldehyde inactivation of cell pellets differed from those of the monolayers, highlighting the importance of inactivation validation. …”
Get full text

Recent Advances in Early Earthquake Magnitude Estimation by Using Machine Learning Algorithms: A Systematic Review by Andrés Navarro-Rodríguez, Oscar Alberto Castro-Artola, Enrique Efrén García-Guerrero, Oscar Adrian Aguirre-Castro, Ulises Jesús Tamayo-Pérez, César Alberto López-Mercado, Everardo Inzunza-Gonzalez

“…Machine learning (ML) has emerged as a powerful tool to enhance the accuracy of these applications, enabling more efficient responses to seismic events of different magnitudes. …”
Get full text

R&D Expenditure and Innovation in the EU and Selected Member States by Radka MacGregor Pelikánová

“…Undoubtedly, innovation is indispensable and needs to be financed. However, the relation of involved factors and the related dynamic are unclear and have not received sufficient scientific and academic attention. …”
Get full text

Data and Knowledge Dual-Driven Creep Life Prediction for Austenitic Heat-Resistance Steel by Xiaochang Xie, Mutong Liu, Ping Yang, Zenan Yang, Chengbo Pan, Chenchong Wang, Xiaolu Wei

“…In this study, we collected 216 creep data of austenitic heat-resistant steel, selected a variety of different machine learning algorithms to establish creep life prediction models, calculated and introduced a large amount of physical metallurgy knowledge highly related to creep based on Thermo-Calc, and converted the creep life into the form of the Larson–Miller parameter to optimize the data distribution, which effectively improved the prediction accuracy and interpretability of the model. …”
Get full text

Engineering Moxifloxacin-Encapsulated Liposome-Enriched Alginate Hydrogel Films by Ismail Bal, Meltem Macit, Ali Alasiri, Onur Cem Namli, Muhammad Sohail Arshad, Zeeshan Ahmad, Gulengul Duman, Israfil Kucuk

“…MXF was encapsulated in soy lecithin (SL:MXF:2:1) via the probe sonication method with an average efficiency of 80%. Two different manufacturing methods, including a micropipetting and a T-shaped microfluidic junction (TMJ) device technique, were used to incorporate the MXF-encapsulated liposomes into hydrogel matrices and layered as a coating on polymeric substrate material. …”
Get full text

Study of Probiotics as Biostimulants and Biofortifiers in Seed Germination by Stephany Nefertari Chávez García, Raúl Rodríguez Herrera, Julia Medrano Macías, Sendar Nery Flores, Sonia Yesenia Silva Belmares, Adriana Carolina Flores Gallegos

“…The efficiency of probiotic production was also determined. …”
Get full text

Development of a Correlation Model of Adherence to Sports With the Mental Health of Students Participating in Sports Leisure Time by Ahmad Mahmoudi, Mohammad Ghasemi, Reza Amin Zadeh, Danesh Zamani Rad

“…Therefore, the lowest average rating is related to the depression component and the highest average rating is related to the physical component. …”
Get full text

Genetic background of body reserves in laying hens through backfat thickness phenotyping by Bédère, Nicolas, Dupont, Joëlle, Baumard, Yannick, Staub, Christophe, Gourichon, David, Frédéric, Elleboudt, Le Roy, Pascale, Zerjal, Tatiana

“…The two lines largely differed in body fatness: the efficient line had larger backfat and lower chemerin levels compared to the inefficient line. …”
Get full text

Optimization of In Vivo Studies by Combining Planar Dynamic and Tomographic Imaging: Workflow Evaluation on a Superparamagnetic Nanoparticles System by Maritina Rouchota, Alessio Adamiano, Michele Iafisco, Eirini Fragogeorgi, Irineos Pilatis, Gilles Doumont, Sébastien Boutry, Daniele Catalucci, Argyro Zacharioudaki, George C. Kagadis

“…Molecular imaging holds great promise in the noninvasive monitoring of several diseases with nanoparticles (NPs) being considered an efficient imaging tool for cancer, central nervous system, and heart- or bone-related diseases and for disorders of the mononuclear phagocytic system (MPS). …”
Get full text

Dissecting the Affinity of Neighboring Malvaceae Genera; <i>Brachychiton</i> and <i>Sterculia</i> Through Morphological, Anatomical, and Molecular Approaches by Fatma A. Hamada, Doaa M. Elkholy, Rim Hamdy, Mohamed Zamzam, Ahmed M. El-Taher, Hammad Ahmad Jan, Nagwan H. Atia

“…While the morphological and anatomical features demonstrated a close relationship between the studied intrageneric species, the DNA barcoding analysis proved very efficient in distinguishing the two neighboring genera. …”
Get full text

Dissecting genomes of multiple yak populations: unveiling ancestry and high-altitude adaptation through whole-genome resequencing analysis by Sheikh Firdous Ahmad, Munish Gangwar, Amit Kumar, Amod Kumar, Mahesh Shivanand Dige, Girish Kumar Jha, Gyanendra Kumar Gaur, Triveni Dutt

“…The study included 105 individuals from three distinct yak populations i.e., Indian yak (n = 29); Chinese yak (n = 61) and wild yak (n = 15), hypothesized to be related along the evolutionary timescale. Efficient variant calling and quality control in GATK and PLINK programs resulted in around 1 million (1,002,970) high-quality (LD-independent) SNPs with an average genotyping rate of 96.55%. …”
Get full text

Salt-Tolerant Bacteria Support Salinity Stress Mitigating Impact of Arbuscular Mycorrhizal Fungi in Maize (<i>Zea mays</i> L.) by Randa M. Zaki, Aida H. Afify, Eman H. Ashour, Ahmed M. El-Sawah

“…We isolated ninety-seven salt-tolerant bacterial isolates, and these isolates show a high ability to grow under different concentrations of NaCl. The nine most efficient isolates show a high ability to produce indole acetic acid (IAA), gibberellic acid (GA), P-solubilized exopolysaccharides (EPS), proline, and antioxidants under different NaCl concentrations. …”
Get full text

Statistical analysis of the established salary in small and medium enterprises by Yu. S. Pin’kovetskaya

“…The quality of the developed models was checked according to the Kolmogorov-Smirnov, Pearson and Shapiro-Wilk criteria.The obtained results have some theoretical significance, in particular, when conducting research related to the justification of the proposed wage of employees of enterprises different in number, the formation of measures for increasing efficiency of the entrepreneurial sector activity. …”
Get full text

Unrecorded Butterfly Species and Potential Local Extinctions: The Role of Citizen Science and Sampling by S. Alberti, A. Pollo, C. Cerrato, R. Viterbi, E. Balletto, L. Dapporto, S. Bonelli, I. Piccini

“…The study also aims to assess the extinction potential of the butterflies in relation to functional traits. The results showed that even if there were significant differences in the number of records between the three sources, there were no significant differences for species recorded. …”
Get full text

Movement competency in rowing: the key to an effective stroke by Natalie Legge, Katie Slattery, Katie Slattery, Mark Watsford, Mark Watsford, Damien O’Meara, Frank Nugent, Frank Nugent

“…The concept of sport-specific movement competency for rowing could provide benefits for rowing participation, technical rowing efficiency, injury prevention and performance enhancement.…”
Get full text

Development and characterization of a high internal phase Pickering emulsion stabilized by whey protein–based nanoparticles with excellent antioxidant activity for 3-dimensional pr... by Yaoyao Ji, Yidan Sun, Yanjiao Chang, Haiqing Ye, Xue Shen

“…Herein, whey protein–based nanoparticles with curcumin (Cur) and different amounts of proanthocyanins (PC) incorporated exerted reduced surface tension, enhanced particle size, Cur loading efficiency, 3-phase contact angle, interfacial protein adsorption, and surface load with increasing PC content, making them excellent Pickering stabilizers for HIPPE. …”
Get full text

Effects of low glucose microenvironment on the proliferation, migration and senescence of meniscus-derived stem cells by Jiabei Tong, Badr Alzahrani, Suresh Kumar Subbiah, Sanjiv Rampal, Rajesh Ramasamy, Zhijie Ma, Xiaoyun Wu, Pooi Ling Mok

“…Large-scale cell expansion in vitro is usually accompanied by decreased proliferation and migration and increased senescence, leading to a decrease in treatment efficiency. Therefore, the present study aimed to compare the effects of different concentrations of glucose on the proliferation, migration, senescence and protein expression of MeSCs. …”
Get full text