Effects of evidence-based ICU care on long-term outcomes of patients with sepsis or septic shock (ILOSS): protocol for a multicentre prospective observational cohort study in Japan by Alan Kawarai Lefor, Takayuki Ogura, Kunihiko Takahashi, Kensuke Nakamura, Toru Kotani, Daisuke Taniguchi, Daisuke Kasugai, Keibun Liu, Yasunari Morita, Kenji Fujizuka, Takai Chihiro, Kenzo Ishii, Daisetsu Yasumura, Tomohiro Hamagami, Nobutake Shimojo, Masakazu Nitta, Takashi Hongo, Kazuki Akieda, Maeda Atsuo, Tadashi Kaneko, Yutaka Sakuda, Kohkichi Andoh, Akiyoshi Nagatomi, Yukiko Tanaka, Yuhei Irie, Hiroshi Kamijo, Manabu Hanazawa, Matsuoka Ayaka, Kenji Oike, Hajime Katsukawa

“…The findings will be published in peer-reviewed journals and presented at scientific conferences.Trial registration number UMIN000041433.…”
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Direct maternal morbidity and the risk of pregnancy-related deaths, stillbirths, and neonatal deaths in South Asia and sub-Saharan Africa: A population-based prospective cohort stu... by Fahad Aftab, Imran Ahmed, Salahuddin Ahmed, Said Mohammed Ali, Seeba Amenga-Etego, Shabina Ariff, Rajiv Bahl, Abdullah H Baqui, Nazma Begum, Zulfiqar A Bhutta, Godfrey Biemba, Simon Cousens, Vinita Das, Saikat Deb, Usha Dhingra, Arup Dutta, Karen Edmond, Fabian Esamai, Amit Kumar Ghosh, Peter Gisore, Caroline Grogan, Davidson H Hamer, Julie Herlihy, Lisa Hurt, Muhammad Ilyas, Fyezah Jehan, Mohammed Hamad Juma, Michel Kalonji, Rasheda Khanam, Betty R Kirkwood, Aarti Kumar, Alok Kumar, Vishwajeet Kumar, Alexander Manu, Irene Marete, Usma Mehmood, Nicole Minckas, Shambhavi Mishra, Dipak K Mitra, Mamun Ibne Moin, Karim Muhammad, Sam Newton, Serge Ngaima, Andre Nguwo, Muhammad Imran Nisar, John Otomba, Mohammad Abdul Quaiyum, Sophie Sarrassat, Sunil Sazawal, Katherine E Semrau, Caitlin Shannon, Vinay Pratap Singh, Sajid Soofi, Seyi Soremekun, Atifa Mohammed Suleiman, Venantius Sunday, Thandassery R Dilip, Antoinette Tshefu, Yaqub Wasan, Kojo Yeboah-Antwi, Sachiyo Yoshida, Anita K Zaidi, Alliance for Maternal and Newborn Health Improvement (AMANHI) maternal morbidity study group

“…We used standard operating procedures, data collection tools, and training to harmonise study implementation across sites. Three home visits during pregnancy and 2 home visits after birth were conducted to collect maternal morbidity information and maternal, foetal, and newborn outcomes. …”
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Effectiveness of Group Problem Management Plus, a brief psychological intervention for adults affected by humanitarian disasters in Nepal: A cluster randomized controlled trial. by Mark J D Jordans, Brandon A Kohrt, Manaswi Sangraula, Elizabeth L Turner, Xueqi Wang, Pragya Shrestha, Renasha Ghimire, Edith Van't Hof, Richard A Bryant, Katie S Dawson, Kedar Marahatta, Nagendra P Luitel, Mark van Ommeren

“…<h4>Trial registration</h4>ClinicalTrials.gov NCT03747055.…”
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Improving access and efficiency of acute ischemic stroke treatment across four Canadian provinces: a stepped-wedge trial by Noreen Kamal, Noreen Kamal, Noreen Kamal, Elena A. Cora, Elena A. Cora, Simone Alim, Judah Goldstein, Judah Goldstein, David Volders, David Volders, Shadi Aljendi, Heather Williams, Patrick T. Fok, Patrick T. Fok, Patrick T. Fok, Etienne van der Linde, Trish Helm-Neima, Renee Cashin, Brian Metcalfe, Brian Metcalfe, Julie Savoie, Wendy Simpkin, Cassie Chisholm, Michael D Hill, Bijoy K. Menon, Stephen Phillips, Stephen Phillips

“…In-person activities might be critical to ensure fidelity of the intervention.Clinical trial registrationISRCTN11109800, https://www.isrctn.com/ISRCTN11109800.…”
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Exploring the factors that influence engagement with and experiences of integrated care for adults at risk of cardiovascular disease and mild-to-moderate mental health concerns in... by Alison R. McKinlay, Neil Howlett, Vivi Antonopoulou, Fabiana Lorencatto, Laura J. McGowan, David Osborn, Amy O’Donnell, Emily J. Oliver, Ivo Vlaev, Falko F. Sniehotta, Michael P. Kelly, Susan Michie, Caroline Kemp, Yannis Pappas, Gurch Randhawa, Nasreen Ali, Emily Munro, Angel M Chater

“…Systematic review registration: PROSPERO (CRD42024554282.…”
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Management and outcomes of gastrointestinal congenital anomalies in low, middle and high income countries: protocol for a multicentre, international, prospective cohort study by Yang Liu, Nick Sevdalis, Melika Akhbari, Niyi Ade-Ajayi, Justine Davies, Dan Poenaru, Dominique Vervoort, Hannah Thompson, Lubna Samad, Stephen Tabiri, Muhammad Arshad, Emily Smith, Lars Hagander, Kokila Lakhoo, Godfrey Sama Philipo, Adesoji Ademuyiwa, Emmanuel Ameh, Cristiana Riboni, Naomi Jane Wright, Laura Herrera, Nana Adofo-Ansong, Harmony Ubhi, Samuel Parker, Sadi Abukhalaf, Ahmad Alhamid, Osaid H. Alser, Emrah Aydin, Yousra-Imane Benaskeur, Shrouk M. Elghazaly, Safa Abdal Elrais, Sophia Hashim, Gabriella Hyman, Henang Kwasau, Bruno Martinez-Leo, Kelly Naranjo, Ibrahim Nour, Mahmoud Saleh, Patricia Shinondo, Marcus Sim, Agota Vaitkiene, Isabelle Williams, Aayenah Yunus, Muhammad Amjad Chaudhary, Muhammad Adnan Khan Khattak, Muhammad Bin Amjad, Marlene Dominguez Anaya, Samiul Hasan, Paolo Bragagnini, Segundo Rite, Hana Arbab, Aqil Soomro, Raed Nael Al-Taher, Ibrahim Rabi Nour, Osama Abdul Kareen Sarhan, Taimur Qureshi, Hina Yousaf, Candy S.C. Choo, Doris Mae Dimatatac, Shireen Anne Nah, Vijay Anand Ismavel, Ann Miriam, Shajin T, Monica Ivanov, Andreea Serban, Eva Blazquez-Gomez, Luis Garcia-Aparicio, Marti Iriondo, Jordi Prat, Xavier Tarrado, Emma Svensson, Alhassan Abdul-Mumin, Dominic Bagbio, Sheila Owusu, Dayang Anita Abdul Aziz

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Cluster randomised controlled trial of double-dose azithromycin mass drug administration, facial cleanliness and fly control measures for trachoma control in Oromia, Ethiopia: the... by Robert Butcher, David Macleod, Helen Anne Weiss, Matthew J Burton, Esmael Habtamu, Bart Versteeg, Virginia Sarah, Anthony Solomon, James G Logan, Anna R Last, Alexandra Czerniewska, Oumer Shafi Abdurahman, Katie Greenland, Ailie Robinson, Claire Collin, Edao Sinba Etu, Meseret Guye, Demitu Legesse, Kedir Temam Nuri, Gemeda Shuka, Munira Haji Mohammed Yousuf, Gaddisa Dheressa, Gebeyehu Dumessa, Melesse Akalu, Mesfin Tadesse, Dereje Adugna Kumsa, Fikre Seife Gebretsadik, Aida Abashawl, Wondu Alemayehu

“…Multiple rounds of SAFE implementation have proven insufficient to eliminate trachoma in Ethiopia, where over 50% of the global trachoma burden remains. …”
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Health outcomes, utility and costs of returning incidental results from genomic sequencing in a Canadian cancer population: protocol for a mixed-methods randomised controlled trial by Mark Robson, Christine Elser, Wanrudee Isaranuwatchai, Melyssa Aronson, Salma Shickh, Marc Clausen, Chloe Mighton, Mariana Gutierrez Salazar, Kathleen-Rose Zakoor, Rita Kodida, Emma Reble, Andrea Eisen, Seema Panchal, Tracy Graham, Susan Randall Armel, Chantal F Morel, Ramzi Fattouh, Emily Glogowski, Kasmintan A Schrader, Jada G Hamilton, Kenneth Offit, June C Carroll, Raymond H Kim, Jordan Lerner-Ellis, Kevin E Thorpe, Andreas Laupacis, Yvonne Bombard

“…However, large-scale implementation of genomic sequencing faces challenges, especially with regard to the return of incidental results, which refer to genetic variants uncovered during testing that are unrelated to the primary disease under investigation, but of potential clinical significance. …”
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Accurate Fruit Phenotype Reconstruction via Geometry-Smooth Neural Implicit Surface by Wei Ying, Kewei Hu, Ayham Ahmed, Zhenfeng Yi, Junhong Zhao, Hanwen Kang

“…To quantitatively evaluate the performance of this method, traditional point cloud registration on 3D scanning data is implemented for comparison. …”
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Model Solutions and Pragmatism in Developing ICT for Public Consultations by Anna Przybylska

“…No less important for the institutionalization of deliberative public consultations is the controversy over registration and verification, and consequently, the recruitment of participants. …”
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Barriers and enablers for the deployment of large language model-based conversational robots for older adults: A protocol for a systematic review of qualitative studies. by Ravi Shankar, Anjali Bundele, Amartya Mukhopadhyay

“…This systematic review will provide timely insights to guide the responsible development and deployment of AI companions for seniors.<h4>Trial registration</h4>ClinicalTrials.gov CRD42024601264.…”
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Therapeutic exercise protocol for the prevention of anterior cruciate ligament injuries in female soccer players with dynamic knee valgus (RCT) by Amanda Coves García, Emilio José Poveda Pagán

“…Discussion This protocol aims to be one of the first to implement an ACL injury prevention program for women footballers with DKV. …”
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An audit of the death certification process in Wales by Indrajit Nair, V Adhiyaman

“…We reaudited the process in February 2025 and collected data on the following timelines: informing and making the notes available to the MES, time for medical scrutiny, time to complete the Medical Certificate for the cause of death (MCCD), mistakes in MCCD, and time to registration of death.Results Discussion: Our results showed that there were considerable delays after implementing the statutory system. …”
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Assessing the Land Consolidation Projects from the Perspective of Farmers (A Case Study in Artova District of Tokat Province in Turkey) by Esra Kaplan, Hayriye Sibel Gülse Bal

“…This study was aimed to measure and assess the knowledge, expectation and attitudes of farmers on the land consolidation project planned to be implemented for some villages in Artova District of Tokat Province, Turkey. …”
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Effectiveness of unguided internet-based computer self-help platforms for eating disorders (with or without an associated app): A systematic review. by Alessandra Diana Gentile, Yosua Yan Kristian, Erica Cini

“…<h4>Trial registration</h4>Prospero (CRD42024520866).…”
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Evaluating the efficacy of support groups in the metaverse for Ukrainian refugees: a protocol for a randomized clinical trial by Cezar Giosan, Cătălina-Maria Popoviciu, Saltanat Zhamaliyeva, Iuliana Zaborot, George Deac

“…Traditional support group interventions might be challenging to implement for geographically dispersed populations, making the metaverse an innovative and inclusive platform for providing much-needed support to such populations. …”
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Validation of visual analog scales of mood and anxiety at the workplace. by Frédéric Dutheil, Clara Palgen, Georges Brousse, Thomas Cornet, Martial Mermillod, Ines Lakbar, Guillaume Vallet, Julien S Baker, Jeannot Schmidt, Barbara Charbotel, Bruno Pereira, Louis Delamarre

“…We recommend validated questionnaires for at-risk patients.<h4>Trial registration</h4><h4>Clinicaltrials</h4>gov: NCT02596737. …”
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A Critical Review of Bangladesh's Child Labor Regulations and Policies by Md Mahmudul Hoque

“…Institutional bodies collaborate to implement and monitor these policies and programs designed to reduce child labor. …”
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Regulation of the geographical indications as a intensifying for exporting Ukrainian companies’ goods to EU markets by K.V., V.V., V.A.

“…In the system of international trade law there is a separate subsystem for regulating trade aspects of intellectual property rights, particular with regard to geographical indications. Due to the need to implement the Association Agreement with the EU, the problem of implementing the requirements of the relevant WTO agreement and related EU directives and regulations is becoming important. …”
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Measurement methods updating for tandem-generator EGP-10K with using of digital technology by I. P. Dryapachenko, V. E. Kovtun, E. M. Mozhzhukhin, V. V. Ostashko, Yu. M. Pavlenko, O. I. Rundel, A. F. Sharov

“…This paper presents the results of modernization of infrastructure of the experimental studies with the beams of the accelerator EGP-10K using the latest equipment and modern digital technique for beam diagnostics, registration of the reaction products and visualization of the obtained data.…”
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