The Prehabilitation Radiotherapy Exercise, smoking Habit cessation and Balanced diet Study (PREHABS) protocol to explore the feasibility of embedding behavioural modifications into... by Matthew Callister, Kevin Franks, Rachael L Murray, Jenny Hewison, Gillian Williams, Alison Boland, Emma Morgan, Carole Burnett, Cecilia Pompili, Janine Bestall, Shaunna Burke, Samuel Greenwood-Wilson, Andy Sloss

“…Feasibility will be assessed by measuring acceptability, demand and implementation. The duration of the study is 24 months. …”
Get full text

Evaluation of the feasibility, acceptability, and impact of Group Antenatal Care at the health post level on continuation in antenatal care and facility based delivery in Ethiopia... by Reena Sethi, Rediet Fasil, Walelegn W. Yallew, Della Berhanu, Yenealem Woldemariam, Gayane Yenokyan, Alemayehu Worku, Dedefo Teshite, Konjit Wolde, Anne Hyre, Stephanie Suhowatsky, Lisa Noguchi

“…The design will include three time periods: first is a six-month control period with no G-ANC implementation, followed by another six months period where G-ANC will be introduced in half (n=18) of the study health posts, then final six months where G-ANC will be implemented in the remaining 18 health posts. …”
Get full text

Smartphone intervention for pregnancy smoking cessation with peer support: the study protocol of the SmokeFree Together 2.0 (SFT 2.0) randomised controlled trial by Ken Resnicow, Kristie Foley, Daniel Muresan, Oana M Blaga, Marina D Dascal, Alexandra Onișor, Teodora Frățilă, Andreea Morar, Dan Mihu, Cristian I Iuhas, Gabriela Caracostea, Cristian I Meghea

“…Herein, we report the methods used to develop, implement and test the feasibility and effectiveness of a novel adaptive mobile pregnancy tobacco cessation app-based intervention using deep tailoring and a self-nominated supporter.Methods and analysis The study is a type II hybrid effectiveness-implementation randomised controlled trial. …”
Get full text

Prevalence of hematological malignancies in Africa: A systematic review and meta-analysis by Zewudu Mulatie, Dereje Mengesha Berta, Alemu Gedefie, Hussen Ebrahim, Brukitawit Eshetu, Tesfaye Gessese, Mihret Tilahun, Seada Ali, Habtu Debash, Yeshimebet Kassa, Ermiyas Alemayehu

“…We evaluated publication bias through the implementation of a funnel plot and Egger’s test and conducted a sensitivity analysis. …”
Get full text

A cash transfer plus gender transformative economic empowerment intervention seeking to improve the wellbeing of caregivers of children and adolescents living with HIV in South Afr... by Darshini Govindasamy, Nwabisa Shai, Nelly Mwandacha, Stanley Carries, Nokwanda Sithole, Kalysha Closson, Arvin Bhana, Lovemore Sigwadhi, Laura Washington, Andrew Gibbs, Angela Kaida

“…The primary outcomes include consent rate, overall retention rate, workshops retention rate, cash transfer protocol adherence, staff perceptions on implementation, psychological wellbeing, depressive symptoms, and IPV. …”
Get full text

The Australian Traumatic Brain Injury Initiative: Review and Recommendations for Outcome Measures for Use With Adults and Children After Moderate-to-Severe Traumatic Brain Injury by Jennie L. Ponsford, Amelia J. Hicks, Matthew K. Bagg, Ruby Phyland, Sarah Carrier, Amelia C. James, Natasha A. Lannin, Nick Rushworth, Terence J. O'Brien, Peter A. Cameron, D. Jamie Cooper, Regina Hill, Belinda J Gabbe, Melinda Fitzgerald

“…These 11 outcome measures will be included as common data elements in the AUS-TBI data dictionary. Review Registration PROSPERO (CRD42022290954).…”
Get full text

Bedside counseling on complementary medicine as a new model in pediatric cancer care—protocol of the SiKOM multicenter prospective cohort study by Lara Nowak, Daniela Reis, Rebecca Büttner, Melanie Schwermer, Jennifer Bals, David D. Martin, David D. Martin, Thomas Ostermann, Alfred Längler, Alfred Längler, Heidemarie Haller, Tycho Zuzak, Tycho Zuzak

“…This prototype support care model will serve as a framework for implementing complementary medicine counseling both within and beyond inpatient pediatric oncology settings. …”
Get full text

Effectiveness of a standardised and interactive intervention to prevent preschooler unintentional injury in rural China: a cluster randomised controlled trial by Jie Li, Guoqing Hu, David C Schwebel, Min Zhao, Peishan Ning, Wanhui Wang, Jieyi He, Weiqiang Li

“…Sensitivity analyses supported the principal findings.Conclusion The 9-month interactive intervention decreased unintentional injury incidence and substantially increased preschooler’s safety knowledge in rural China, offering an effective option for implementing or integrating in multifactorial interventions in resource-limited areas.Trial registration number Chinese Clinical Trial Registry, CHiCTR2000038025.…”
Get full text

Comparison of the four co-created interventions to improve snacking and physical activity behaviour in European adolescents: the SEEDS project by Judit Queral, Elisabet Llauradó, Annemieke Wargers, Wilma Jansen, Yannis Manios, Amandine Senequier, Craig A. Williams, Dimitris Vlachopoulos, Rosa Solà, Lucia Tarro

“…Abstract Background New approaches involving adolescents in designing and implementing interventions are an opportunity to improve healthy lifestyles. …”
Get full text

Screening for depression among Spanish-speaking patients in primary care settings within the USA: a scoping review protocol to inform clinical practices by Andrew Creamer, Aden Littlewood, Linda E Guzman, Hannah E Frank

“…While some research exists on depression screening in linguistically diverse settings, the use of validated Spanish-language screenings in primary care settings is underexplored when it comes to implementing the USPSTF’s recommendation. This scoping review addresses this knowledge gap by (1) assessing the extent to which Spanish-speaking patients in the USA receive depression screening in Spanish and (2) using the Consolidated Framework for Implementation Research (CFIR) 2.0 to categorise barriers and facilitators to implementing Spanish-language depression screening tools in USA primary care settings. …”
Get full text

Nurse-led weaning protocols—a systematic review and meta-analysis by Yingying Wang, Yingying Wang, Yan Wang, Su Gu, Liqun Zhu, Ruixiao Jia, Min Tan, Shaoyong Ma

“…Further high-quality, large-scale research is needed to confirm the effectiveness and safety of nurse-led weaning protocols in diverse clinical settings.Systematic review registrationIdentifier: CRD42023487455, https://www.crd.york.ac.uk/prospero.…”
Get full text

Performance of an ultrasound diagnostic algorithm for acute dyspneic patients in the emergency department: an EMERALD-US protocol by Adrien Bassand, Tahar Chouihed, Nicolas Girerd, Xavier Lepage, Ludovic Merckle, Anthony Chauvin, Aurélien Buessler, Deborah Jaeger, Kevin Duarte, Charlene Duchanois, Jérôme Bokobza, Alice Penine, Gaetan Giacomin, Cyrielle Brossard

“…Misdiagnosis of dyspneic patients on ED admission has been associated with inappropriate treatment, prolonged hospital stays and increased mortality, particularly among elderly patients. The implementation of protocols like the EMERALD-US algorithm can help physicians in expedited decision-making and diagnosis without increasing ED visit durations.Trial registration number NCT03691857.…”
Get full text

Attitudes and expectations toward medication review among community pharmacy customers in Germany: a cross-sectional study by Cathrin J. Vogt, Annika Wiegand, Kire Trajkov, Michael Metzner, Viktoria S. Wurmbach, Anja Braem, Hanna M. Seidling

“…By clearly explaining the purpose and expected benefits of medication reviews, the outreach and impact could be increased.Trial registration: German Clinical Trials Register identifier: DRKS00032446.…”
Get full text

An Automated Conversational Agent Self-Help Program: Randomized Controlled Trial by Heather M Foran, Christian Kubb, Janina Mueller, Spencer Poff, Megan Ung, Margaret Li, Eric Michael Smith, Akinniyi Akinyemi, Melanie Kambadur, Franziska Waller, Mario Graf, Y-Lan Boureau

“…ObjectiveThis study aims to develop and test the effectiveness and implementation of a new, widely targeted conversational agent prevention program (Zenny) designed to enhance well-being. …”
Get full text

Pulmonary and Physical Virtual Reality Exercises for Patients With Blunt Chest Trauma: Randomized Clinical Trial by Tjitske D Groenveld, Indy GM Smits, Naomi Scholten, Marjan de Vries, Harry van Goor, Vincent MA Stirler

“…Patient experiences and barriers and facilitators toward implementation were assessed through interviews. …”
Get full text

Effectiveness of physical therapy on pain, disability and quality of life in women with lumbopelvic pain in postpartum period: a systematic review with evidence gap map and meta-an... by Fatih Özyurt, Esra Üzelpasacı, Abdulhamit Tayfur, Türkan Akbayrak

“…Systematic review registration number (PROSPERO) CRD42023485978.…”
Get full text

Anaesthesiologists’ guideline adherence in pre-operative evaluation: a retrospective observational study by Simone Maria Kagerbauer, Jennifer Wißler, Manfred Blobner, Ferdinand Biegert, Dimislav Ivanov Andonov, Gerhard Schneider, Armin Horst Podtschaske, Bernhard Ulm, Bettina Jungwirth

“…Abstract Background Surveys suggest a low level of implementation of clinical guidelines, although they are intended to improve the quality of treatment and patient safety. …”
Get full text

Uptake and use of a minimum data set (MDS) for older people living and dying in care homes in England: a realist review protocol by Claire Goodman, Julienne Meyer, Karen Spilsbury, Barbara Hanratty, Lisa Irvine, Sarah Kelly, Massirfufulay Kpehe Musa, Gizdem Akdur, Adam Gordon, Guy Peryer, Anne Killett, Jennifer Burton, Sue Fortescue, Ann-Marie Towers

“…The aim of this realist review is to develop a theory-driven understanding of how care home staff implement and use MDS to plan and deliver care of individual residents.Methods and analysis A realist review will be conducted in three research stages.Stage 1 will scope the literature and develop candidate programme theories of what ensures effective uptake and sustained implementation of an MDS.Stage2 will test and refine these theories through further iterative searches of the evidence from the literature to establish how effective uptake of an MDS can be achieved.Stage 3 will consult with relevant stakeholders to test or refine the programme theory (theories) of how an MDS works at the resident level of care for different stakeholders and in what circumstances. …”
Get full text

Co-Benefits of Largescale Organic farming On huMan health (BLOOM): Protocol for a cluster-randomised controlled evaluation of the Andhra Pradesh Community-managed Natural Farming p... by Lindsay M Jaacks, Lilia Bliznashka, Peter Craig, Michael Eddleston, Alfred Gathorne-Hardy, Ranjit Kumar, Sailesh Mohan, John Norrie, Sheril Rajan, Aditi Roy, Bharath Yandrapu, Nikhil Srinivasapura Venkateshmurthy, Poornima Prabhakaran

“…The BLOOM study (co-Benefits of Largescale Organic farming On huMan health) aims to determine if a government-implemented agroecology programme reduces pesticide exposure and improves dietary diversity in agricultural households. …”
Get full text

Triage test for all-oral drug-resistant tuberculosis (DR-TB) regimen: a phase IV study to assess effectiveness, feasibility, acceptability and cost-effectiveness of the Xpert MTB/X... by Kogieleum Naidoo, Derek J Sloan, Wilber Sabiiti, Bariki Mtafya, Stephen H Gillespie, Aderonke Agbaje, Nyanda Elias Ntinginya, Morten Ruhwald, Agnes Gebhard, Anushka Naidoo, Rubeshan Perumal, Getachew Tollera, Evaezi Okpokoro, Alash'le G Abimiku, Everdina W Tiemersma, Sabine M Hermans, Sophia B Georghiou, Kalkidan Yae, Shewki Moga, Hannelise Feyt, Takondwa Kachoka, Marothi P Letsoalo, Andrea M Cabibbe, Letitia Shunmugam, Daniela M Cirillo, Salah Foraida

“…Trial results will be disseminated through conference presentations, peer-reviewed publications and the clinical trial registry.Trial registration number Clinicaltrials.gov; Trial registration number: NCT05175794; South African National Clinical Trials Register (SANCTR DOH-27-012022-4720)…”
Get full text