A blended opioid-free anesthesia protocol and regional parietal blocks in laparoscopic abdominal surgery- a randomized controlled trial by Giuseppe Accurso, Dario Rampulla, Mariaconcetta Cusenza, Giovanni Candela, Paolino Savatteri, Luigi Vetrugno, Antonino Giarratano, Santi Maurizio Raineri

“…OFA eliminates the side effects of opioids and decreases patients’ length of stay and early mobilization without requiring additional drugs. Trial registration ISRCTN15228105. Retrospectively registered 02/12/2023.…”
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Does mobile phone instructional video demonstrating sputum expectoration improve the sputum sample quality and quantity in presumptive pulmonary TB cases? Protocol for a prospectiv... by Siddharudha Shivalli, Amrut Hondappagol, Kibballi Madhukeshwar Akshaya, Abhay Nirgude, Narendra Varun, Raveendra Harohally Ramaiah Reddy, Burugina Nagaraja Sharath

“…Investigators will present the results in scientific forums, publish in a scientific journal, and share with RNTCP officers.Trial registration number Clinical Trial Registry of India (CTRI/2019/06/019887).…”
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Prevention and Health Promotion Interventions for Young People in the Context of Digital Well-Being: Rapid Systematic Review by Michelle Colder Carras, Dahlia Aljuboori, Jing Shi, Mayank Date, Fatima Karkoub, Karla García Ortiz, Fasika Molla Abreha, Johannes Thrul

“…Trial RegistrationPROSPERO CRD42023444387; https://www.crd.york.ac.uk/prospero/display_record.php?…”
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Using Artificial Intelligence to Detect Risk of Family Violence: Protocol for a Systematic Review and Meta-Analysis by Kathleen de Boer, Jessica L Mackelprang, Maja Nedeljkovic, Denny Meyer, Ravi Iyer

“… BackgroundDespite the implementation of prevention strategies, family violence continues to be a prevalent issue worldwide. …”
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Improving Explainability and Integrability of Medical AI to Promote Health Care Professional Acceptance and Use: Mixed Systematic Review by Yushu Liu, Chenxi Liu, Jianing Zheng, Chang Xu, Dan Wang

“… BackgroundThe integration of artificial intelligence (AI) in health care has significant potential, yet its acceptance by health care professionals (HCPs) is essential for successful implementation. Understanding HCPs’ perspectives on the explainability and integrability of medical AI is crucial, as these factors influence their willingness to adopt and effectively use such technologies. …”
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Impact of family-oriented gamification on self-management of people with multiple sclerosis: a mixed-methods study protocol by Arezoo Rasti, Leily Zare, Nahid Dehghan nayeri, Fatemeh Bahramnezhad

“…Well-designed gamification may positively impact health behaviours and enhance collaborative care. However, its implementation in the field of MS in Iran is currently limited. …”
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Nutrition and Exercise in Critical Illness Trial (NEXIS Trial): a protocol of a multicentred, randomised controlled trial of combined cycle ergometry and amino acid supplementation... by Daren K Heyland, Andrew Day, G John Clarke, Catherine (Terri) Hough, D Clark Files, Marina Mourtzakis, Nicolaas Deutz, Dale M Needham, Renee Stapleton

“…We plan to disseminate trial results in peer-reviewed journals, at national and international conferences, and via nutritional and rehabilitation-focused electronic education and knowledge translation platforms.Trial registration number NCT03021902; Pre-results.…”
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Cognitive behavioural therapy in practice-nurse led behaviour-intervention for low back pain in German primary care – qualitative process evaluation of a feasibility study by Gregor Feldmeier, Stefan Zutz, Jennifer Höck, Anja Wollny, Peter Kropp, Attila Altiner, Christin Löffler

“…The involvement of specially trained practice nurses could be useful for the implementation of a CBT-based therapy concept in German primary care due to better accessibility and cost-effectiveness. …”
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Perception, attitude, and demand for Korean medicine and Western medicine collaborative treatment of medical occupational groups in Korea: A scoping review by Jungtae Leem, Kwan-Il Kim, Joo Hee Seo, Moon Joo Cheong, Inae Youn

“…Based on research gap in our scoping review, quantitative studies using validated questionnaire and in-depth interview are needed to identify on-site demand to improve KWCT implementation. Protocol registration: https://www.researchregistry.com/ (reviewregistry830).…”
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Mapping the interactions of critical factors in China’s first-contact healthcare systems using causal loop diagrams by Wenjun He, Yusupujiang Tuersun, Tao Yang, Yuting Wan, Minji Yong, Zizhen Huang, Zhiyong Xiao, Menglin Luo, Yujia Zhang, Yujie Liu, Tao Yang, Yi Qian, Dong Roman Xu

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Integrating artificial intelligence in community-based diabetes care programmes: enhancing inclusiveness, diversity, equity and accessibility a realist review protocol by Valeria E Rac, Joanna Bielecki, Samah Hassan, Sarah Ibrahim, Aleksandra Stanimirovic, Suja Mathew, Ryan Hooey, James Marshall Bowen

“…Ethics approval will be obtained from the University of Toronto; however, following the completion of the realist review for patients and community members’ engagement to support knowledge mobilisation and dissemination to ensure practical application and reciprocity.PROSPERO registration number This protocol was registered at PROSPERO (CRD42025636284).…”
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Effects of neuromuscular electrical stimulation during hemodialysis on muscle strength, functional capacity and postural balance in patients with end-stage renal disease: a randomi... by Amal Machfer, Nadia Fekih, Achraf Ammar, Hayfa Ben Haj Hassen, Wael Daab, Hassen Ibn Hadj Amor, Mohamed Amine Bouzid, Hamdi Chtourou

“…Trial registration Pan African Clinical Trial Registry Identifer: PACTR202206634181851 Registered on 21/06/2022. …”
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Systematic description of the development of a complex health intervention of information and support in a new pregnancy after pregnancy loss by Emily Koert, Sarah Fredsted Villadsen, Rebecca Mackel, Helene Cagara, Tanja Schlaikjær Hartwig, Henriette Svarre Nielsen, Lone Schmidt

“…Through such case study, we hope that future researchers will be inspired to include co-production in their own intervention development projects by seeing that it is valuable and can be feasible and done with limited resources. Trial registration Not applicable.…”
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It’s safe to move! A protocol for a randomised controlled trial investigating the effect of a video designed to increase people’s confidence becoming more active despite back pain... by Ian A Harris, Adrian C Traeger, James H McAuley, Siobhan M Schabrun, Benedict Martin Wand, Aidan Cashin, Christopher Michael Williams, Edel O'Hagan, Sean O'Neill

“…Introduction Social media provide promising contemporary platforms for sharing public health information with a broad audience. Before implementation, testing social media campaigns that are intended to engage audiences and initiate behaviour change is necessary. …”
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Non-randomised prospective clinical trial to improve follow-up adherence, survivorship knowledge and late effects documentation at a childhood cancer clinic in Western Kenya: a stu... by Festus Njuguna, Gertjan Kaspers, Gilbert Olbara, Terry Vik, Jesse Lemmen, Susan Mageto

“…Findings will also be shared with governmental and non-governmental organisations that support children with cancer in Kenya to inform their target audiences and guide their policy development.Lessons learnt from this study could inform healthcare providers and policy makers on how to shape survivorship programmes in the Kenyan context and possibly implement similar programmes in other centres in Sub-Saharan Africa.Trial registration number NCT06680687.…”
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Development and evaluation of an intervention based on the provision of patient feedback to improve patient safety in Spanish primary healthcare centres: study protocol by Joana Ripoll, Joan Llobera, Ignacio Ricci-Cabello, Jose Maria Valderas, Maria J Serrano-Ripoll, Guadalupe Pastor-Moreno, Antonio Olry de Labry Lima

“…The results will be disseminated in peer-reviewed publications and national and international conferences.Trial registration number NCT03837912; pre-results.…”
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Co-Designed Mobile-Based Cognitive Training for Older Chinese Americans: Protocol for a Pilot Randomized Controlled Trial Assessing Feasibility and Acceptability by Tingzhong Xue, Aybey Amy Wei, Bei Wu, Camilla Sanders, Eleanor Schildwachter McConnell, Hanzhang Xu

“…Trial RegistrationClinicalTrials.gov NCT05355870; https://clinicaltrials.gov/study/NCT05355870 International Registered Report Identifier (IRRID)PRR1-10.2196/69303…”
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Sustainability of Interprofessional Education: Protocol for a Scoping Review by Nathalia Hanany Silva de Oliveira, Renata Fonsêca Sousa de Oliveira, Juliana Pontes Soares, Janete Lima de Castro

“…Trial RegistrationOpen Science Framework 5VNJS; https://osf.io/5vnjs/ International Registered Report Identifier (IRRID)DERR1-10.2196/60763…”
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Study protocol on advance care planning in multiple sclerosis (ConCure-SM): intervention construction and multicentre feasibility trial by Alberto Gajofatto, Simone Veronese, Leigh Manson, Andrea Giordano, Ludovica De Panfilis, Michela Bruzzone, Marta Cascioli, Maria Grazia Grasso, Paola Kruger, Sara Montepietra

“…Findings from both phases will be disseminated widely through peer-reviewed publications, conferences and workshops.Trial registration number ISRCTN48527663; Pre-results.…”
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Just-in-time adaptive interventions for adolescent and young adult health and well-being: protocol for a systematic review by Caroline A Figueroa, Kathleen W Guan, Christopher Adlung, Loes Keijsers, Crystal R Smit, Annabel Vreeker, Eva Thalassinou, Eeske van Roekel, Mark de Reuver

“…We will disseminate the review findings through peer-reviewed journal publication, conferences and stakeholder meetings to inform participatory research.PROSPERO registration number CRD42023473117.…”
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