Digital cognitive behavioural therapy intervention in the workplace: study protocol for a feasibility randomised waitlist-controlled trial to improve employee mental well-being, en... by Nicole K Y Tang, Caroline Meyer, Talar Rita Moukhtarian, Krishane Patel, Carla Toro, Guy Daly, Lukasz Walasek, Sean Russell

“…Digital interventions provide low cost and easily scalable delivery methods to implement psychological interventions in the workplace. …”
Get full text

Randomised controlled trial in women with coronary artery disease investigating the effects of aerobic interval training versus moderate intensity continuous exercise in cardiac re... by Paul I Oh, Leanna S Lee, Ming-Chang Tsai, Dina Brooks

“…The per protocol treatment effect analysis, however, unveiled a 0.95 mL kg-1 min-1 improvement in V̇O2peak in response to AIT over MICE (p<0.001).Conclusions Further research is necessary to elucidate the patient profile and circumstances under which the potential for the implementation of AIT may be individualised, and offered in clinical practice.Trial registration NCT02966158.…”
Get full text

Web-based support for self-management strategies versus usual care for people with COPD in primary healthcare: a protocol for a randomised, 12-month, parallel-group pragmatic trial by André Nyberg, Tobias Stenlund, Sara Lundell, Karin Wadell

“…Findings will be presented at conferences, submitted for publication in peer-reviewed journals and presented to the involved healthcare professionals, participants and patient organisations.Trial registration number NCT03746873…”
Get full text

Reasonable access to brief behavioural insomnia treatment among medical and psychiatric outpatients (RABBIT): a multicentre randomised controlled trial protocol by Toshi A Furukawa, Kenta Matsumura, Masatsugu Sakata, Makie Nagai, Hiroku Noma, Hitomi Oi, Jun Shigematsu, Shun Nakajima

“…The analysis will be performed on an intention-to-treat basis.Ethics and dissemination This study has been approved by the Ethics Committee for Clinical and Epidemiological Research of Toyama University (approval no. R2023152).Trial registration number UMIN000052911; pre-results.…”
Get full text

Impact of public-funded health insurances in India on health care utilisation and financial risk protection: a systematic review by Bhaskaran Unnikrishnan, Shradha S Parsekar, Bhageerathy Reshmi, Eti Rajwar, Ratheebhai Vijayamma, Bhumika Tumkur Venkatesh

“…Cross-sectional studies with comparison, impact evaluations, difference-in-difference design based on before and after implementation of the scheme, pre–post, experimental trials and quasi-randomised trials were eligible for inclusion.Data extraction and synthesis Data extraction was performed by three reviewers independently. …”
Get full text

Effects of a home-based aromatherapy programme for the management of behavioural and psychological symptoms of dementia among older persons with dementia: A randomised controlled t... by Becky Siu Yin Li, Ankie Tan Cheung, Ka Ming Chow, Carmen Wing Han Chan

“…A comprehensive process evaluation was conducted to evaluate programme implementation and participants’ perceptions. The primary outcome was the severity of BPSD in OPWDs, with secondary outcomes being OPWDs’ quality of life (QoL) and caregivers’ distress and care burden. …”
Get full text

Effects of traditional Chinese exercise on lung function and mental health in patients with COPD: a systematic review and meta-analysis by Shuning Liu, Debin Xu

“…This study not only highlights the value of TCE as a nonpharmacological intervention but also offers new directions for psychological management, warranting broader implementation.Systematic review registrationCRD42024586079, https://www.crd.york.ac.uk/PROSPERO/view/CRD42024586079.…”
Get full text

The Review of the Situation on Anthrax in 2024 in the World, the Forecast for 2025 in the Russian Federation by A. G. Ryazanova, D. K. Gerasimenko, T. M. Golovinskaya, O. N. Skudareva, F. V. Logvin, O. V. Semenova, L. Yu. Aksenova, E. I. Eremenko, G. A. Pechkovsky, K. A. Oleynikova, A. V. Nikitina, A. N. Kulichenko

“…The incidence of anthrax in animals and humans in 2025 in the Russian Federation will depend on the scale of animal registration and vaccination measures, the completeness of inclusion of population at risk in immunization scheme and implementation of preventive vaccination plans. …”
Get full text

Mixed-methods feasibility outcomes for a novel ACT-based video game ‘ACTing Minds’ to support mental health by Darren J Edwards, Andrew H Kemp, Tom C Gordon

“…Themes reflect participants’ desire for an engaging therapeutic experience, use of game for exploring emotions, as well as their perspectives on how they had applied their learning to the real world.Secondary results Quantitative results indicated small to large effect sizes associated with decreases in depression (ηp2 = 0.011), anxiety (ηp2 = 0.096) and stress (ηp2 = 0.108), and increases in psychological flexibility (ηp2 = 0.060), social connectedness (ηp2 = 0.021), well-being (ηp2 = 0.011) and participation in usual activities (ηp2 = .307).Conclusions Implementation of the ‘ACTing Minds’ intervention is warranted, based on both qualitative and quantitative outcomes.Trial registration number NCT04566042 ClinicalTrials.gov…”
Get full text

Safety and efficacy of genomic biomarker-guided neoadjuvant therapy for locally advanced and oligometastatic prostate cancer (SEGNO): study protocol for an open-label prospective p... by Haichao Huang, Tao Wang, Wei Li, Zhun Wu, Xuegang Wang, Jinchun Xing, Bin Chen, Kaiyan Zhang

“…Trial registration Clinicaltrial.gov, NCT06387056.…”
Get full text

Perinatal mortality: Trends in prevalence and association with birth weight by Violetta A. Vybornykh

“…Special emphasis should be placed on strengthening efforts aimed at achieving shared goals with the WHO: enhancing the capacity of the healthcare system during the perinatal period; improving the quality of care for mothers and newborns from pregnancy through the postpartum period; and advancing methods for monitoring, program implementation, and accurate registration of every newborn and every stillbirth. …”
Get full text

Community-Engaged Mental Health and Wellbeing Initiatives in Under-Resourced Settings: A Scoping Review of Primary Studies by Muhammad Chutiyami, Natalie Cutler, Sopin Sangon, Tusana Thaweekoon, Patcharin Nintachan, Wilai Napa, Phachongchit Kraithaworn, Jo River

“…Studies conducted in English language, involving community members in the initiatives’ design or implementation and targeting 1 or more mental health/wellbeing outcomes, were included. …”
Get full text

A mixed-methods formative process evaluation of the falls management exercise programme in an English county by Patricia Jessiman, Ruth Salway, Rona Campbell

“…Study registration Researchregistry9560.…”
Get full text

Effect of the COVID-19 pandemic and lockdown on cancer stage distribution and time to treatment initiation using cancer registry data of the Swiss cantons of Zurich and Zug from 20... by Flurina Suter, Miriam Wanner, Andreas Wicki, Dimitri Korol, Sabine Rohrmann

“…However, we cannot exclude that the implementation of the new Swiss law on cancer registration in 2020 explains part of our observations.…”
Get full text

Effectiveness and acceptability of exergaming in people with mild cognitive impairment: protocol for an overview of systematic reviews and network meta-analysis by Xi Chen, Dian Jiang, Yifei Chen, Yishu Zhu, Hongting Ning, Hui Feng

“…Systematic review registration PROSPERO CRD42023421052.…”
Get full text

Effect of computerised, knowledge-based, clinical decision support systems on patient-reported and clinical outcomes of patients with chronic disease managed in primary care settin... by Nikolaos Mastellos, Marie line El Asmar, Kanika I Dharmayat, Antonio J Vallejo-Vaz, Ryan Irwin

“…Further research is needed to provide evidence on the intervention effect and the interplay between healthcare setting features, CDSS characteristics and implementation processes.PROSPERO registration number CRD42020218184.…”
Get full text

Сost-effectiveness of the second wave of protease inhibitors in the treatment of chronic hepatitis C (genotype 1) in patients not previously treated with antiviral drugs, and for r... by A. V. Rudakova, D. A. Gusev, A. N. Uskov, L. N. Konovalova, Yu. V. Lobzin

“…Due to substantial variability of PI prices, it is advisable to take into account local pricing at regional programs implementation.…”
Get full text

PEPsy-CM study protocol: impact of a 3-year program for early psychosis based on case-management on relapse rate, a French multicenter randomized trial by Aurélie Schandrin, Julie Jourdan, Sihame Chkair, Sophie Bouvet, Pascale Fabbro-Peray, Mocrane Abbar, for the PEPsy-CM working group

“…The medico-economic evaluation is a strength of the study, as economic objectives are too infrequently considered in such studies. Trial registration www.clinicaltrials.gov number NCT05116514 registered on 05/10/2021…”
Get full text

The impact of enhanced cleaning on bacterial contamination of the hospital environmental surfaces: a clinical trial in critical care unit in an Egyptian hospital by Nermine Mahmoud Hassan Hamed, Osama Ahmed Deif, Aleya Hanafy El-Zoka, Magda Mohamed Abdel-Atty, Mohamed Fakhry Hussein

“…Clinical trial registration number PACTR202402531001186, date: 15 February 2024, ‘retrospectively registered’.…”
Get full text

Enhancing Adherence to Continuous Positive Airway Pressure Therapy in Patients With Obstructive Sleep Apnea Using Augmented Reality: Protocol for a Randomized Controlled Trial by Ming-Che Chen, Yen-Chin Chen, Cheng-Yu Lin

“…ObjectiveThis clinical trial aims to examine the feasibility of AR implementation and the effect of AR on improving CPAP adherence in patients with OSA. …”
Get full text