Scaling up the Med-South Lifestyle Program in public health settings to reduce chronic disease risk: a hybrid implementation-effectiveness study by Carmen D. Samuel-Hodge, Carmen D. Samuel-Hodge, Lisa Pham, Kiira Lyons, Lindy B. Draeger, Li Jiang, Feng-Chang Lin, Rachel Ram, Jennifer Leeman

“…For sedentary behaviors, daily sitting time was significantly reduced.ConclusionsThese results show successfully adapted implementation and delivery approaches to fit Med-South into the context of public health settings during the COVID-19 pandemic.Trial RegistrationClinicalTrials.gov: NCT05067816, October 5, 2021.…”
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Evaluation on the effectiveness on the implementation of WHO caregiver skills training (CST) programme in Hong Kong: a randomised controlled trial protocol by Wai-Ching Paul Wong, Siu-Lun Chow

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Research and Implementation of Distributed Computing Management System for College Students’ Sports Health Based on Integrated Regional Collaborative Medical Care by Mian Wang, Lijuan Li

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Perceptions of 3R implementation in European animal research: A systematic review, meta-analysis, and meta-synthesis of barriers and facilitators. by Edwin Louis-Maerten, Aoife Milford, David M Shaw, Lester D Geneviève, Bernice S Elger

“…<h4>Objectives</h4>The purpose of this systematic review was to examine how the scientific community in Europe that is involved with research with animals perceives and experiences the implementation of 3R (Replace, Reduce, Refine).<h4>Methods</h4>A systematic search of the literature published in the past ten years was performed in PubMed, Web of Science and Scopus. …”
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Right-restricting measures implemented by Public Health Surveillance services during the COVID-19 pandemic: a systematic review protocol by Tiago Correia, Marcelo Dayrell Vivas, Larissa Bragagnolo, Igor Antônio Lourenço da Silva, Fernando Tureck, Reinaldo Santos, Samara Kielmann, Debora do Carmo, Camila Avarca, Franciele da Silva, Mariana Paes, Luis Fernando Nogueira Tofani, Arthur Chioro

“…The results will be presented in one or more articles to be submitted to scientific journals and may also be presented at scientific conferences and to public policy makers.PROSPERO registration number This systematic review protocol was registered with the International Prospective Register of Systematic Reviews (PROSPERO) on 20 November 2024 (registration number CRD42024613039).…”
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The implementation and appraisal of a novel confirmatory HIV-1 testing algorithm in the Microbicides Development Programme 301 Trial (MDP301). by Ute Jentsch, Precious Lunga, Charles Lacey, Jonathan Weber, Janet Cairns, Gisela Pinheiro, Sarah Joseph, Wendy Stevens, Sheena McCormack

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A mixed methods process evaluation of the implementation of a peer coaching intervention to improve the execution of preventive tasks by occupational physicians by S. Orhan Pees, S. H. van Oostrom, F. G. Schaafsma, K. I. Proper

“…Specifically, the evaluation seeks to: (1) describe the reach and uptake of the intervention program; (2) determine the extent to which the program was implemented as intended; (3) provide insights into experiences of OPs, and (4) identify factors influencing the implementation. …”
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Technology to improve reliable access to oxygen in Western Uganda: study protocol for a phased implementation trial in neonatal and paediatric wards by Graham Moore, Hamish Graham, Rami Subhi, Sheillah Bagayana, Joseph Mugerwa, David Peake, Eleanor Nakintu, Daniel Murokora, Roger Rassool, Marc Sklar, Bryn Sobott

“…Broader dissemination will include publication in peer-reviewed journals and academic conference presentations.Trial registration number ACTRN12621000241831.…”
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Systems thinking with active implementation research (STAIR): Protocol for a school-based randomised control trial for childhood obesity prevention. by Michelle Jackson, Jillian Whelan, Steven Allender, Luke Wolfenden, Melanie Nichols, Vicki Brown, Sze Lin Yoong, Liliana Orellana, Kristy A Bolton, Penelope Love, Prabhat Lamichhane, Nicole Nathan, Colin Bell

“…<h4>Introduction</h4>This paper presents the protocol for the effectiveness-implementation trial: Systems Thinking with Active Implementation Research (STAIR) for childhood obesity prevention. …”
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The Use of Digital Technologies for the Purpose of Improving Methodological Approaches to the Creation of a Pharmaceutical Quality System at Enterprises for the Production of Medic... by V. V. Goryachkin, V. А. Smirnov, V. N. Shestakov, R. A. Abramovich

“…Their active use at pharmaceutical enterprises is intended to contribute to ensuring the proper implementation and uninterrupted functioning of pharmaceutical quality systems, through constant monitoring of the quality of manufactured products and registration of manufactured batches in high-precision information storage systems.…”
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Efficacy and safety of the early implementation of a multimodal rehabilitation program in mechanically ventilated patients: A randomized clinical trial protocol. by Jorge Iván Alvarado Sánchez, Laura Maria Castillo Morales, Yenny Rocio Cardenas Bolivar, Valentina Montañez Nariño, Maria Valentina Stozitzky Ríos, Catherine Lissell Arévalo Guerrero, Miguel Leonardo Pulido Bobadilla, Diana Marcela Melo Rojas, Ana Gabriela López Rubio, Diana Carolina Ortíz Moreno, Paula Andrea Barreto Garzón, Marisol Murillo, Andrés Felipe Mora-Salamanca

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Digital solution for salutogenic brain health: a pilot sequential multiple assignment randomised trial (SMART) protocol for clinical implementation by Nick Sevdalis, Nicholas Graves, Jing Xu, Bibhas Chakraborty, Wentao Zhou, Yuanxi Jia, Yanhong Dong, Nicole Yun Ching Chen, Claire See Ying Chang, Vanessa Phua, Xiang Cong Tham, Wei Fong Liau

“…Data will be analysed by study team members and findings will be published in peer-reviewed journals.Trial registration number NCT06582316.…”
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Evidence based QUality Improvement for Prescribing Stewardship in ICU (EQUIPS-ICU): protocol for type III hybrid implementation-effectiveness study by Duncan Wagstaff, John Amuasi, Sumaiya Arfin, Diptesh Aryal, Mohd Basri Mat Nor, Joseph Bonney, Arjen Dondorp, David Dongelmans, Layoni Dullawe, Fathima Fazla, Aniruddha Ghose, Eva Hanciles, Rashan Haniffa, Madiha Hashmi, Adam Hewitt Smith, Bharath Kumar, Yen Lam Minh, Ramani Moonesinghe, Luigi Pisani, Cornelius Sendagire, Mohd Shahnaz Hasan, Maryam Shamal Ghalib, Moses Siaw Frimpong, Otavio Ranzani, Menbeu Sultan, David Thomson, Swagata Tripathy, Louise Thwaites, Rabiul Alam Md. Erfan Uddin, Mohd Zulfakar Mazlan, Wangari Waweru-Siika, Abigail Beane

“…Evaluation of implementation, and the determinants of its success, is informed by the RE-AIM framework and the Consolidated Framework for Implementation Research respectively. …”
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Factors affecting the implementation of calcium supplementation strategies during pregnancy to prevent pre-eclampsia: a mixed-methods systematic review by Taryn Young, Ana Pilar Betran, Hema Mistry, Richard Riley, Shakila Thangaratinam, Guillermo Carroli, Edgardo Abalos, Zahida P Qureshi, John Allotey, Anna Thorson, Meghan A Bohren, Rana Islamiah Zahroh, G Justus Hofmeyr, Juan Pablo Peña-Rosas, Alfredo Palacios, Thaís Rocha, Joshua Peter Vogel, Luc Smits, Gabriela Cormick, Koiwah Koi Larbi, Kym IE Snell, Hellen Moraa, George N Gwako

“…These review findings can inform implementation to ensure effective and equitable provision and scale-up of calcium interventions.PROSPERO registration number CRD42021239143.…”
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Kangaroo Mother Care implementation research to develop models for accelerating scale-up in India and Ethiopia: study protocol for an adequacy evaluation by Anteneh Asefa, Rajiv Bahl, Sarmila Mazumder, Nita Bhandari, Jose Martines, Lynn M Sibley, Nalini Singhal, Khalid Aziz, Thomas Brune, Araya Abrha Medhanyie, Hibret Alemu, Selemawit Asfaw Beyene, Fisseha Ashebir Gebregizabher, Habtamu Beyene, Grace Chan, John N Cranmer, G Darmstadt, Dereje Duguma, Addisalem Fikre, Bizuayehu Gashaw Andualem, Abebe Gebremariam Gobezayehu, Tedros Hailu Abay, H L Mohan, Arun Jadaun, K Jayanna, F N U Kajal, Arin Kar, Raghav Krishna, Aarti Kumar, Vishwajeet Kumar, Tarun Kumar Madhur, Mulusew Lijalem Belew, Rajini M, Hajira Amin, Prem K Mony, Mekonnen Muleta, Cynthia Pileggi-Castro, Suman Pn Rao, Abiy Seifu Estifanos, Henok Tadele, Abraham Tariku, Ephrem Tekle Lemango, Birkneh Tilahun Tadesse, Ravi Upadhyay, Bogale Worku, Marta Yemane Hadush, Grace J Chan, Gary Lee Darmstadt, HL Mohan, Krishnamurthy Jayanna, M Rajini, Jose Carlos Martines, Hajira Mohammed Amin, Suman Rao, Ravi Prakash Upadhyay

“…Results of the project will be submitted to a peer-reviewed journal for publication, in addition to national and global level dissemination.Study status WHO approved protocol: V.4—12 May 2016—Protocol ID: ERC 2716. Study implementation beginning: April 2017. Study end: expected March 2019.Trial registration number Community Empowerment Laboratory, Uttar Pradesh, India (ISRCTN12286667); St John's National Academy of Health Sciences, Bangalore, India and Karnataka Health Promotion Trust, Bangalore, India (CTRI/2017/07/008988); Society for Applied Studies, Delhi (NCT03098069); Oromia, Ethiopia (NCT03419416); Amhara, SNNPR and Tigray, Ethiopia (NCT03506698).…”
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Supervised exercise-based rehabilitation for people with intermittent claudication-Study protocol for a Danish implementation process (StRiDE). by Sara Fredslund Hajdú, Helle Bøgard, Thomas Vedste Aagaard, Stine Gundtoft Roikjær, Charlotte Simonÿ, Anne Dalhoff, Kim Houlind, Alexander Luijk, Ida Ulriksen, Lotte Therkildsen Jensen, Søren T Skou, Lars Hermann Tang

“…This is a protocol presenting the implementation process of supervised exercise therapy and smoking cessation in a region of Denmark.…”
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Study protocol for assessing the effectiveness, implementation fidelity and uptake of attachment & child health (ATTACH™) Online: helping children vulnerable to early adversity by Nicole Letourneau, Lubna Anis, Cui Cui, Ian D. Graham, Kharah Ross, Kendra Nixon, Jan Reimer, Miranda Pilipchuk, Emily Wang, Simone Lalonde, Suzanna Varro, Maria Jose Santana, Ashley Stewart-Tufescu, Angela Soulsby, Barbara Tiedemann, Leslie Hill, Tiffany Beks, Martha Hart

“…Registration number: NCT05994027. Date of registration: July 22, 2023. …”
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Multiple-family group intervention programming to improve mental health of adolescents living with HIV/AIDS in Ghana: An implementation science study protocol. by Dorothy Serwaa Boakye, Samuel Adjorlolo

“…<h4>Date of trial registration</h4>24 November, 2024.…”
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Process evaluation of a cluster randomised implementation trial examining strategies to increase early access to exercise for people with knee osteoarthritis: protocol by Jocelyn L Bowden, Kathryn Mills, Justine M Naylor, Joseph Descallar, Robert Boland, Margery Pardey, Amy Orsatti

“…Registration occurred in December 2022…”
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The implementability and proximal effects of a transdiagnostic mental health intervention for adolescents (Kort): protocol for a mixed-methods intensive longitudinal study by Thomas Engell, Siri Saugestad Helland, Emily Gabriela Vira, Silje Berg, Line Solheim Kvamme, John Kjøbli, Josefine Bergseth, Inga Brenne, Ragnhild Bang Nes, Espen Røysamb, Line Brager-Larsen, Anette Jeneson, Ane Lønsetteig, Ole-Martin Vangen, Knut-Petter Leinan, Anneli Mellblom

“…Abstract Background This protocol describes a study designed to test the implementability and proximal effects of a transdiagnostic mental health intervention for adolescents in school health services. …”
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