Effectiveness of care coordination interventions delivered to stroke survivors in low and middle-income countries: Systematic review and meta-analysis protocol. by Stephanopoulos Kofi Junior Osei, Anthony Danso-Appiah

“…This systematic review will identify the key components of stroke care coordination interventions implemented in low and middle-income countries (LMICs) and assess their effectiveness on stroke outcomes such as motor recovery, cognitive function, mental health, stroke type and the role of stroke severity, type, and the nature of the interventions in influencing these outcomes.…”
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Assessing and Enhancing Nutrition and Physical Activity Environments in Early Childhood Education and Care Centers: Scoping Review of eHealth Tools by Joyce Hayek, Kelsi Dickson, Lynne M Z Lafave

“… BackgroundEarly childhood is a critical period for shaping lifelong health behaviors, making early childhood education and care (ECEC) environments ideal for implementing nutrition and physical activity interventions. eHealth tools are increasingly utilized in ECEC settings due to their accessibility, scalability, and cost-effectiveness, demonstrating promise in enhancing educators’ practices. …”
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Mamá Empoderada: study protocol for a pilot trial of a novel parenting and mental health prevention intervention for migrant mothers with young children at the Mexico-US border by Gudelia Rangel, Shira M Goldenberg, Eileen Pitpitan, Kaylee Ramage, Ietza Bojorquez-Chapela, Cecilia Martinez-Torteya, Katherine Rosenblum, Chelsie Hernandez, Monica Alvarez

“…If efficacious, this intervention is highly promising as a novel, low-cost, and feasible model that could be implemented in border settings in Mexico, the USA and elsewhere. …”
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A Novel Presurgical Risk Prediction Model for Chronic Post-Surgical Pain in Adults Undergoing Surgical Procedures: Development and Internal Validation of the P4-Prevoque Questionna... by Wildemeersch D, Wauters E, Roelant E, Verhaegen I, De Clerck GR, Dankerlui R, Saldien V, Hans GH

“…Using four straightforward and readily available questions, the proposed user-friendly prediction model has the strength to be easily implemented in daily practice. Future research should focus on its further validation.Trial Registration: ClinicalTrials.gov NCT05526976, Ethics Committee B3002022000112.Keywords: chronic post-surgical pain, clinical prediction model, perioperative care, postoperative pain, preoperative evaluation, recovery after surgery…”
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Health Navigator intervention to address the unmet social needs of populations living with cancer attending outpatient treatment at a major metropolitan hospital in Australia: prot... by Sean Martin, Kate Neadley, Annabel Smith, Mark Boyd, Christopher Hocking, Cheryl Shoubridge

“…Most HN interventions are implemented in primary care, despite evidence that disadvantaged populations face substantial barriers to accessing such care, and these interventions are limited in Australia. …”
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Long-term biological and behavioural impact of an adolescent sexual health intervention in Tanzania: follow-up survey of the community-based MEMA kwa Vijana Trial. by Aoife M Doyle, David A Ross, Kaballa Maganja, Kathy Baisley, Clemens Masesa, Aura Andreasen, Mary L Plummer, Angela I N Obasi, Helen A Weiss, Saidi Kapiga, Deborah Watson-Jones, John Changalucha, Richard J Hayes, MEMA kwa Vijana Trial Study Group

“…Since January 1999, an adolescent sexual and reproductive health (SRH) intervention has been implemented in ten randomly chosen intervention communities in rural Tanzania, within a community randomised trial (see below; NCT00248469). …”
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Safety and Efficacy of Modular Digital Psychotherapy for Social Anxiety: Randomized Controlled Trial by Mona M Garvert, Jessica McFadyen, Stuart Linke, Tayla McCloud, Sofie S Meyer, Sandra Sobanska, Paul B Sharp, Alex Long, Quentin J M Huys, Mandana Ahmadi

“…We developed a novel digital adaptation of CBT for social anxiety that is both modular and fully digital without a therapist in the loop and implemented it in the smartphone app Alena. …”
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SToP (See, Treat, Prevent) skin sores and scabies trial: study protocol for a cluster randomised, stepped-wedge trial for skin disease control in remote Western Australia by Marianne J Mullane, Timothy C Barnett, Jeffrey W Cannon, Jonathan R Carapetis, Ray Christophers, Juli Coffin, Frieda Mc Loughlin, Vicki O'Donnell, Rebecca Pavlos, Bec Smith, Andrew C Steer, Steven Y C Tong, Roz Walker, Asha C Bowen

“…Communication and dissemination will require ongoing consultation with Aboriginal communities to determine appropriate formats.Trial registration number ACTRN12618000520235.…”
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The Combined Effect of Multisensory Stimulation and Therapist Support on Physical and Mental Health of Older Adults Living in Nursing Homes: Pilot Randomized Controlled Trial by Sewar Khatib, Yuval Palgi, Yoni K Ashar, Natalya Polyvyannaya, Pavel Goldstein

“…Trial RegistrationClinicalTrials.gov NCT05394389; https://clinicaltrials.gov/ct2/show/NCT05394389…”
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Health-related quality of life in populations with diabetes, prediabetes, and normal glycemic levels in Guangzhou, China: a cross-sectional study by Meichen Li, Na Liu, Guli Jiang, Hongli Zeng, Jianwen Guo, Darong Wu, Darong Wu, Hui Zhou, Zehuai Wen, Zehuai Wen, Li Zhou, Li Zhou

“…These findings emphasize the clinical necessity for implementing targeted interventions to optimize HRQoL outcomes in these high-risk subgroups, which aligns with the fundamental objectives of contemporary diabetes management frameworks.Clinical trial registrationClinicalTrials.gov ID: NCT05315895.…”
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Early mental health intervention and supported self-care for LGBTQ+ young people in the UK: a mixed-methods study by Elizabeth McDermott, Rachael Eastham, Elizabeth Hughes, Emily Pattison, Katherine Johnson, Stephanie Davis, Steven Pryjmachuk, Ceu Mateus, Olu Jenzen, Felix McNulty

“…Study registration This study is registered as PROSPERO CRD42019135722. …”
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Supporting self-management with an internet intervention for low back pain in primary care: a RCT (SupportBack 2) by Adam W A Geraghty, Taeko Becque, Lisa C Roberts, Jonathan Hill, Nadine E Foster, Lucy Yardley, Beth Stuart, David A Turner, Gareth Griffiths, Frances Webley, Lorraine Durcan, Alannah Morgan, Stephanie Hughes, Sarah Bathers, Stephanie Butler-Walley, Simon Wathall, Gemma Mansell, Malcolm White, Firoza Davies, Paul Little

“…To use a mixed-methods process evaluation to explore issues with the implementation of the interventions, potential mechanisms and contextual factors affecting outcomes. …”
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STatin TReatment for COVID-19 to Optimise NeuroloGical recovERy (STRONGER): study protocol for a randomised, open label clinical trial in patients with persistent neurological symp... by Sharon L Naismith, Mark Woodward, Ruth Peters, Xia Wang, Craig S Anderson, Sophia Zoungas, Cheryl Carcel, Paula Muñoz-Venturelli, Karin Leder, Ian H Harding, Meng Law, Julian Elliott, Owen Hutchings, Carlos Delfino, Xiaolei Lin, Nirupama Wijesuriya, Ximena Stecher

“…All participants provided written informed consent.Trial registration number The study protocol is registered at Clinicaltrials.gov (NCT04904536).…”
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Comparing and assessing physical activity and sedentary behaviour guidelines for different populations with and without chronic conditions and/or disabilities: a systematic review... by George P Nassis, Hashel Al Tunaiji, Ashokan Arumugam, Jean-Philippe Chaput, Paddy C Dempsey, Suzanne McDonough, Arto J Pesola, Reime Jamal Shalash, Raneen Mohammad Qadah, Nour Alsaafin, Shima A Mohammad Zadeh, Senthil Kumaran D, Sarah J Moss, Tamrin Veldsman, Sivapriya Ramakrishnan, Raja Regan, Esha Arora, Sulfikar Ali A, Monica Raja Kumari Raghunathan, Ovidiu Constantin Baltatu, Charlotte Häger

“…Additionally, we will highlight current knowledge gaps and potential shortcomings in existing guidelines. PROSPERO registration number: CRD42023491339.…”
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Non-inferiority of sodium zirconium cyclosilicate versus potassium-restricted diet in achieving normokalaemia in patients with type 2 diabetes mellitus: protocol for a multicentre,... by Masahiro Yamazaki, Michiaki Fukui, Masahide Hamaguchi, Yoshitaka Hashimoto, Toru Tanaka, Noriyuki Kitagawa, Shinichi Mogami, Akinori Kogure, Michiyo Ishii, Naoto Nakamura, Hiroshi Okada, Takuya Fukuda, Takeshi Tsutsumi, Takafumi Osaka, Junya Hironaka, Genki Kobayashi, Muhei Tanaka, Kazuteru Mitsuhashi, Takashi Yoshimura, Miho Yano, Akane Kitamura, Akio Kishi, Ryo Bamba, Eiko Sato

“…All data obtained from this study will be published in a peer-reviewed journal.Trial registration number jRCTs051230067.…”
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Quasiexperimental intervention study protocol to optimise the use of new antibiotics in Spain: the NEW_SAFE project by Jesús Rodríguez-Baño, Zaira R Palacios-Baena, Clara M Rosso-Fernández, Pilar Retamar, Lucia Valiente de Santis, Natalia Maldonado, Irene Borreguero, Carmen Herrero-Rodríguez, Salvador López-Cárdenas, Franciso J Martínez-Marcos, Andrés Martín-Aspas, Patricia Jiménez-Aguilar, Juan J Castón, Guillermo Ojeda-Burgos, M Pilar Aznarte-Padial, Julia Praena-Segovia, Juan E Corzo-Delgado, M Ángeles Esteban-Moreno

“…The results will be published in peer-reviewed journals and disseminated at national and international conferences.Trial registration number NCT03941951; Pre-results.…”
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Effectiveness of school-based active breaks on classroom behavior, executive functions and physical fitness in children and adolescent: a systematic review by Tomás Reyes-Amigo, Gabriel Salinas-Gallardo, Edgardo Mendoza, Camilo Ovalle-Fernández, Jessica Ibarra-Mora, Nicolás Gómez-Álvarez, Hernaldo Carrasco-Beltrán, Jacqueline Páez-Herrera, Juan Hurtado-Almonácid, Rodrigo Yañez-Sepúlveda, Rafael Zapata-Lamana, Rafael Zapata-Lamana, Felipe Sepúlveda-Figueroa, Jorge Olivares-Arancibia, Jorge Mota

“…More research is needed to fully understand the benefits of implementing active break programs in the classroom.Systematic review registrationPROSPERO, CRD42023448267, available from: https://www.crd.york.ac.uk/prospero/display_record.php?…”
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Effect of HPV integration on prognosis of young women with CIN2 in China: protocol for a multicentre prospective cohort study by Yan Zhang, Huachun Zou, Wei Zhang, Xiaoyuan Huang, Yuan Ren, Ting Hu, Wenyu Lin, Pengming Sun, Kelvin Stefan Osafo, Binhua Dong, Yuhang Zhang, Xiaowen Pu, Xunyuan Tuo, Qiongying Lyu, Wenrong Huang, Huifeng Xue, Shuxia Xu, Jue Su

“…Results will be published in peer-reviewed scientific journals, presented at academic meetings and conferences and released to the public through press releases.Trial registration number ClinicalTrials.gov (NCT05282095); Pre-results.…”
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Atorvastatin and telmisartan do not reduce nasopharyngeal carriage of SARS-CoV-2 in mild or moderate COVID-19 in a phase IIb randomized controlled trial by Fabrice Bonnet, Adama Doumbia, Vanessa Machault, Frederic Nogbou Ello, Pantxika Bellecave, Corine Bernice Akpovo, Baba Toumany Sidibe, Laura Fernandez, Antoine Kouamé, Edgard Adjogoua, Mireille Dosso, Serge Niangoran, Valérie Journot, Serge Paul Eholié

“…Among adults with mild to moderate COVID-19 infection, the addition of telmisartan or atorvastatin, to the standard LPVr treatment is not associated with a better virological or clinical outcome. Trial registration: NCT04466241, registered on 10/07/2020…”
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Understanding and maximising the community impact of seasonal malaria chemoprevention in Burkina Faso (INDIE-SMC): study protocol for a cluster randomised evaluation trial by John Bradley, Alphonse Ouedraogo, Issiaka Soulama, Chris Drakeley, Teun Bousema, Alfred B Tiono, Denise Hien, Sodiomon Bienvenu Sirima, Issa N Ouedraogo, Jean Baptist Yaro, Aïssata Barry, Seyi Soremekun, Marta Moreno, Jean Sawadogo, Markus Gmeiner, Samuel S Sermé, Isabel Byrne, Jordache Ramjith, Lynn Grignard, Simon Koele, Rob ter Heine, Amidou Z Ouedraogo, Edith Sanogo

“…Findings will be published irrespective of their results.Trial registration number NCT05878366.…”
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