Feasibility and preliminary efficacy of a physical activity intervention in adults with lymphoma undergoing treatment by Juliana V. Costa, Alexander R. Lucas, Shannon L. Mihalko, Peter H. Brubaker, Alexandra Marshall, Brianna Leitzelar, Brianna R. Wolle, Samuel Norton, R. Lee Franco, Jeremy Via, Victor Yazbeck, Rakhee Vaidya, Mary Beth Seegars, Ralph D’Agostino, Lynne Wagner, W. Gregory Hundley

“…Potential Implications for Cancer Survivors: Physical activity may be beneficial for improving exercise capacity and health-related quality of life in patients undergoing chemotherapy. Trial registration #NCT01719562 ClinicalTrials.gov. Registered July 2, 2019—retrospectively registered.…”
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Study protocol of Elective Para-aortic and pelvic versus Pelvic only Irradiation in pelvic node positive Cervical cancer: a multicentric open labelled phase III randomised controll... by Sudeep Gupta, Supriya Chopra, Akhil Kapoor, Prachi Mittal, Ankita Gupta, Jeevanshu Jain, Satyajit Pradhan, Abhishek Shinghal, Ankita Rungta Kapoor, Vinay Saini, Sanju Sanju, Prashanth Giridhar, Lincoln Pujari, Zachariah Chowdhury

“…Introduction The revision of International Federation of Gynaecology and Obstetrics staging in 2018 with recommendations to include cross-sectional imaging and a separate stage for node positive disease have opened a lot of uncertainties in implementing the correct treatment approach in these patients. …”
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Study protocol for a multi-centre randomised controlled trial of the Thai early intervention for autism: Assistive Technology for Caregivers (TEI4A-ATC) across nine hospitals in he... by Duangkamol Tangviriyapaiboon, Samai Sirithongthaworn, Vallop Thaineua, Siripon Kanshana, Athithan Sriminipun, Suchitporn Lersilp, Kewalin Panyo, Kansinee Changsom, Mallika Panyaphab, Pimwarat Srikummoon, Salinee Thumronglaohapun, Natthanidnan Sricharoen, Patrinee Traisathit

“…The aim of the present study is to investigate the effectiveness of a computer-based intervention programme for caregivers of children with ASD called the Thai Early Intervention for Autism—Assistive Technology for Caregivers (TEI4A-ATC), designed and implemented by a multidisciplinary team.Method and analysis 160 children and their caregivers are being recruited. …”
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Longitudinal study of symptom burden in outpatients with advanced cancers based on electronic Patient-Reported Outcome (ePRO) platform: a single institution, prospective study prot... by Yan Wang, Qiuling Shi, Zimeng Li, Bingmei Wang, Lili Song, Lili Tang, Ying Pang, Xinkun Han, Chengcheng Zhou, Yuhe Zhou, Shuangzhi He, Yening Zhang, Xiumin Li

“…Introduction An electronic Patient-Reported Outcome (ePRO) platform is needed for implementing evidence-based symptom management in outpatients with advanced cancer. …”
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Impact evaluation of a social protection programme paired with fee waivers on enrolment in Ghana’s National Health Insurance Scheme by Tia M Palermo, Clare Barrington, Elsa Valli, Gustavo Ángeles-Tagliaferro, Marlous de Milliano, Clement Adamba, Tayllor Renee Spadafora, Tia Palermo, Richard de Groot, Isaac Osei-Akoto, Joseph K. Darko, Robert Darko Osei, Francis Dompae, Nana Yaw, Gustavo Angeles, Sudhanshu Handa, Frank Otchere, Marlous de Miliano, Akalpa J Akaligaung, Raymond Aborigo

“…NHIS and LEAP could be better streamlined to ensure poor households fully benefit from both services, in a further step towards integrated social protection.Trial registration number RIDIE-STUDY-ID-55942496d53af.…”
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An observational, multigenerational platform for health systems and population health interventions to minimise intergenerational transmission of non-communicable diseases in India... by Vaman Khadilkar, Tarun Reddy Katapally, Jasmin Bhawra, Neha Kajale, Rubina Mandlik, Vivek Patwardhan, Demi Miriam, Dipali Ladkat, Chidvilas More, Ketan Gondhalekar, Anuradha Vaman Khadilkar

“…Taking a life course perspective, this multigenerational cohort study aims to investigate behavioural, socioecological, and socioeconomic determinants of growth and NCD risk, as well as healthcare access and utilisation among preadolescents and their parents.Methods and analysis The study is being implemented by the Hirabai Cowasji Jehangir Medical Research Institute (HCJMRI) using a prospective, multigenerational cohort design to investigate NCD risk over 15 years. …”
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Modification in ICU design may influence circadian serum cholinesterase activities: a proof-of-concept pilot study by Sebastian Schmidt, Maria Heinrich, Klaus-Dieter Wernecke, Claudia Spies, Laura Hancke, Anika Mueller, Alawi Luetz

“…Modifications to environmental factors could potentially offer neuroprotective benefits and facilitate the realignment of circadian rhythms within the cholinergic system. Clinical trial registration ClinicalTrials.gov: NCT02143661. Registered May 21, 2014.…”
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Economic evaluation of an Australian nurse home visiting programme: a randomised trial at 3 years by Harriet Hiscock, Lisa Gold, Fiona K Mensah, Francesca Orsini, Tracey Bruce, Anna M H Price, Susan Perlen, Shalika Bohingamu Mudiyanselage, Hannah E Bryson, Penelope Dakin, Diana Harris, Kristy Noble

“…Given the relatively high up-front costs of NHV, long-term follow-up is needed to assess the accrual of health and economic benefits over time.Trial registration number ISRCTN89962120.…”
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Understanding the causal effects and heterogeneity between metabolic syndrome and lung function: a nationwide prospective cohort study in China by Jun Wang, Hai-bin Yu, Si-yuan Lei, Huan-rong Ruan, Xiao-chuan Guo, Jian-sheng Li

“…Such causal machine learning models could evolve into clinically useful tools for personalized treatment decisions in MetS. Trial registration Not applicable.…”
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PRO-DIALOG—the effect of a novel dialogue-based parent-teacher conference on mental health in kindergarten children: a cluster randomized controlled trial by Ingvar Bjelland, Gro Janne Wergeland, Christopher Gillberg, Rolf Gjestad, Adrijana Višnjić-Jevtić, Veronica Kibbe Lisæth, Carmela Miniscalco, Amanda Louise Flygel Tufta, Ida Lygre Vermeer, Alicja Renata Sadownik, Philip Wilson, Maj-Britt Posserud

“…Methods Ten kindergartens will be randomly selected to implement DBED, while ten will act as controls, offering ordinary parent-teacher conferences. …”
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Protocol to test the efficacy and safety of frequent applications of skin electrical stimulation for Leber hereditary optic neuropathy: a single-arm, open-label, non-randomised pro... by Sotaro Mori, Yusuke Murai, Kaori Ueda, Mari Sakamoto, Takuji Kurimoto, Yuko Yamada-Nakanishi, Makoto Nakamura, Takayuki Nagai, Fumio Takano

“…In addition, the results of this study will be presented at domestic and international meetings and published in peer-reviewed journals within a year after data is fixed.Trial registration number jRCTs052200033.…”
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Effectiveness of a web-based educational program on climate change awareness, climate activism, and pro-environmental behavior among primary health care in rural areas: a randomize... by Mohamed Hussein Ramadan Atta, Eman Sameh AbdELhay, Islam Sameh AbdELhay, Shaimaa Mohamed Amin, Ahmed Hashem El-Monshed, Sally Mohammed Farghaly Abdelaliem, Amany Anwar Saeed Alabdullah, Rasha Salah Eweida

“…This approach aligns with the World Health Organization’s Global Strategic Directions for Nursing and Midwifery 2021–2025, which aims to achieve global health goals. Trial registration NCT: 06196476.…”
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The magnitude of flaviviruses infection in Ethiopia: a systematic review and meta-analysis by Daniel Gebretsadik Weldehanna, Hussen Ebrahim, Bruktawit Eshetu, Mihret Tilahun, Habtu Debash, Melaku Ashagrie Belete, Agumas Shibabew, Ousman Mohammed, Alemu Gedefie, Saba Gebremichael Tekele, Ermiyas Alemayehu, Zewudu Mulatie

“…Prompt prevention and control strategies should be implemented particularly in outbreak prone areas.…”
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The burden and predictors of hospital-acquired infection in intensive care units across Sub-Sahara Africa: systematic review and metanalysis by Ousman Adal, Yeshimebet Tamir Tsehay, Birhanu Ayenew, Teshager Woldegiyorgis Abate, Gebrehiwot Berie Mekonnen, Sileshi Mulatu, Sosina Tamre Mamo, Temesgen Ayenew, Mengistu Abebe Messelu, Asnake Gashaw Belayneh

“…Strengthening the quality of care and implementing effective infection control measures are recommended to reduce the burden of healthcare-associated infections (HAIs) in sub-Saharan Africa.…”
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The Effectiveness of a Chatbot Single-Session Intervention for People on Waitlists for Eating Disorder Treatment: Randomized Controlled Trial by Gemma Sharp, Bronwyn Dwyer, Alisha Randhawa, Isabella McGrath, Hao Hu

“…Furthermore, the System Usability Scale was implemented at T2 for the chatbot intervention group only. …”
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The Effects of Acupoint Stimulation Combined With Transcutaneous Electrical Nerve Stimulation on Labor Pain: Protocol for a Stepped Wedge Cluster Randomized Controlled Trial by Yiyun Gu, Xiaojiao Wang, Chunxiang Zhu, Hui Min, Jialu Zhang, Liping Mao, Hua Gao, Hangyun Sun, Xinli Zhu, Chunyi Gu

“…MethodsThis is a 12-month stepped wedge cluster randomized trial to be conducted in 4 labor and delivery units (LDUs) at the Obstetrics and Gynecology Hospital of Fudan University. Each unit will implement 4 types of interventions: TENS, acupoint stimulation, TENS combined with acupoint stimulation, and a control group. …”
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Effectiveness of Mobile Health–Based Gamification Interventions for Improving Physical Activity in Individuals With Cardiovascular Diseases: Systematic Review and Meta-Analysis of... by Tianzhuo Yu, Monica Parry, Tianyue Yu, Linqi Xu, Yuejin Wu, Ting Zeng, Xin Leng, Qian Tong, Feng Li

“…The 95% PI suggests that implementing gamification interventions in similar populations in the future will lead to actual effects in promoting PA in the vast majority of cases. …”
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Machine Learning Approaches in High Myopia: Systematic Review and Meta-Analysis by Huiyi Zuo, Baoyu Huang, Jian He, Liying Fang, Minli Huang

“…The meta-analysis was implemented using a bivariate mixed-effects model. In the validation set, subgroup analyses were conducted based on the ML target events (diagnosis and prediction of high myopia and diagnosis of pathological myopia and high myopia-associated glaucoma) and modeling methods. …”
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Text Messaging to Extend School-Based Suicide Prevention: Pilot Randomized Controlled Trial by Anthony R Pisani, Peter A Wyman, Ian Cero, Caroline Kelberman, Kunali Gurditta, Emily Judd, Karen Schmeelk-Cone, David Mohr, David Goldston, Ashkan Ertefaie

“…This study was conducted in a single high school that was already implementing Sources of Strength, so the bar for showing a distinct effect from texting alone was high. …”
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A Classroom-Based Intervention for Reducing Sedentary Behavior and Improving Spinal Health: Pragmatic Stepped-Wedge Feasibility Randomized Controlled Trial by Dominic Fisher, Rentia Maart, Lehana Thabane, Quinette Louw

“…Furthermore, we recommend contextualized teacher training on how sit-stand desks and HEMVs can be used as classroom management tools. Trial RegistrationPan African Trials Registry PACTR201811799476016; https://tinyurl.com/y4upoys8 International Registered Report Identifier (IRRID)RR2-10.2196/18522…”
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