Development of hypertensive complications in oocyte donation pregnancy: protocol for a systematic review and individual participant data meta-analysis (DONOR IPD) by Saskia le Cessie, Marie-Louise van der Hoorn, Jan van Lith, Eileen Lashley, Kim van Bentem

“…Results will be disseminated through peer-reviewed journals and international conferences.PROSPERO registration number CRD42021267908.…”
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Determinants of inappropriate antibiotic prescription in primary care in developed countries with general practitioners as gatekeepers: a systematic review and construction of a fr... by Mattijs E Numans, Frederike L Büchner, Martijn Sijbom, Nicholas H Saadah, Mark G J de Boer

“…Objectives This study aimed to identify determinants of inappropriate antibiotic prescription in primary care in developed countries and to construct a framework with the determinants to help understand which actions can best be targeted to counteract development of antimicrobial resistance (AMR).Design A systematic review of peer-reviewed studies reporting determinants of inappropriate antibiotic prescription published through 9 September 2021 in PubMed, Embase, Web of Science and the Cochrane Library was performed.Setting All studies focusing on primary care in developed countries where general practitioners (GPs) act as gatekeepers for referral to medical specialists and hospital care were included.Results Seventeen studies fulfilled the inclusion criteria and were used for the analysis which identified 45 determinants of inappropriate antibiotic prescription. …”
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Health outcomes, healthcare use and development in children born into or growing up in single-parent households: a systematic review study protocol by Pia Hardelid, Jenny Woodman, Katie Harron, Alice Armitage, Elizabeth Ingram, Irina Lut

“…This is consistent for key health and development outcomes including physical health, psychological well-being and educational attainment. …”
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Development of the DONOR prediction model on the risk of hypertensive complications in oocyte donation pregnancy: study protocol for a multicentre cohort study in the Netherlands by Saskia le Cessie, Géraldine C M Lafeber, Vera H W Van der Endt, Yvonne Louwers, Marie-Louise P van der Hoorn, Eileen E L O Lashley

“…Following data collection, a multivariate logistic regression model will be developed for the binary outcome hypertensive complication ‘yes’ and ‘no’. …”
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Development of a core outcome set for studies on prevention and management of pregnancy-associated venous thromboembolism (COSPVenTE): a study protocol by Rohan D’Souza, Alexandria King, Lizabeth Teshler, Nadine Shehata, Ann K Malinowski

“…Introduction Pregnancy and post partum are times of heightened risk for the development of venous thromboembolism (VTE), which in turn is one of the leading causes of maternal mortality and long-term morbidity. …”
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Development and acceptance of a new adherence monitoring package to identify non-adherent patients with polypharmacy in primary care: a feasibility study by Andreas Zeller, Samuel Allemann, Isabelle Arnet, Fine Dietrich

“…Practical tools to assess adherence to polypharmacy in primary care are missing.Aims We aimed to develop an Adherence Monitoring Package (AMoPac) for general practitioners (GPs) to identify patient non-adherence. …”
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Implementation research to develop an optimized delivery model for effective implementation of evidence-based interventions to reduce stillbirth in India: A study protocol. by Gadapani Barsha Pathak, Reema Mukherjee, Vani Kandpal, Abhishek Agarwal, Prem Mony, Maryann Washington, Sarmila Mazumder, N K Arora

“…<h4>Trial registration</h4>ClinicalTrials.gov CTRI-2024/07/069796.…”
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Development and testing of a videogame intervention for symptom management among 8–18 years old children with cancer: a study protocol by Rubina Barolia, Zehra Fadoo, Sehrish Sajjad, Raisa B Gul, Saleem Sayani, Ahmed N Abbasi

“…Moreover, their preferences for the development of the videogame were also elicited. Based on the findings from relevant literature and the interviews, we developed the videogame in collaboration with clinical and digital experts in the study’s second phase. …”
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Value of General Movements Assessment in Predicting Neuromotor Development Outcomes in Neonates with Neonatal Respiratory Distress Syndrome: A Prospective Cohort Study by Hainan Wang, Chun Su, Ming Zhang, Peng Liu, Wei Chen

“…Conclusions: GMA has a favorable predictive value for neuromotor development outcomes in children with NRDS. Clinical Trial Registration: ChiCTR2200061223.…”
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Major Adverse Kidney Events in Hospitalized Older Patients With Acute Kidney Injury: Machine Learning–Based Model Development and Validation Study by Xiao-Qin Luo, Ning-Ya Zhang, Ying-Hao Deng, Hong-Shen Wang, Yi-Xin Kang, Shao-Bin Duan

“…Trial RegistrationChinese Clinical Trial Registry ChiCTR2200061610; https://tinyurl.com/3smf9nuw…”
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iKids study protocol: a longitudinal study to understand the impact of interactive electronic devices on the development and health of young children in England by Jenny Retzler, Daniel Jones, John J Reilly, John Stephenson, Stuart Fairclough, Christine Smith, Amy Hughes, Tony Okely, Liane Beretta De Azevedo, João Paulo de Aguiar Greca, Colette Marr

“…Introduction There is evidence of both positive and negative impacts of interactive electronic devices (IEDs), such as tablets and smartphones, on young children’s development and health outcomes. Consultations with early years practitioners, parents and policy makers recognise IEDs as a valuable resource for early-year learning. …”
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The effect of acute branched-chain amino acids ingestion on rate of force development in different time intervals: a controlled crossover study by Xi-Nuan Zhang, Long-Ji Li, Yan-Hao Tu, Li-Feng Zhang, Hua-Yu Shang, Meng Liu, Ming-Da Li

“…However, their impact on the rate of force development (RFD), an indicator of explosive muscle strength, has not yet been validated. …”
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Development and feasibility of a conceptual model for planning individualised physical exercise training (IPET) for older adults: a cross-sectional study by Karen Søgaard, Lars Holm, Sanel Teljigovic, Louise Fleng Sandal, Tina Dalager, Nina Odgaard Nielsen, Gisela Sjøgaard, Mette Bahn Ejvang

“…Eight of 20 training combinations were used, clustering the 115 participants primarily in three main training combinations.Discussion This study shows that older adults vary in physical functioning, indicating that exercise preferences and rehabilitation needs are individual.Trial registration number NCT04862481.…”
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Development of an Online Scenario-Based Tool to Enable Research Participation and Public Engagement in Cystic Fibrosis Newborn Screening: Mixed Methods Study by Louise Moody, Samantha Clarke, Matt Compton, Rachael Hughson-Gill, Felicity Boardman, Corinna Clark, Pru Holder, James R Bonham, Jane Chudleigh

“…MethodsAround 4 development workshops with policymakers, parents, and other stakeholders informed the design of an interactive activity, including the structure, content, and questions posed. …”
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Protocol for developing a core outcome set for medicines safety at transitions of care: a systematic review, qualitative study and Delphi consensus by Fiona Boland, Patrick Redmond, Tamasine C Grimes, Carmel Hughes, Mariam Molokhia, Ibidun Fakoya, Lise M Bjerre, C Alice Oborne, Ryan Jayesinghe

“…The findings of this project will be disseminated through peer-reviewed publications, conference presentations and registration with the COMET Initiative. Members of the Delphi panel will receive summaries of the outputs, and findings will also be shared with the patient and public involvement groups involved in the study through lay summaries. …”
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Core Outcome Set Development for Tension-Type Headache Treatment Using Traditional Chinese Medicine: Protocol for a Delphi Consensus Study by Guojing Fu, Yunmeng Chen, Xiao Liang, Chunli Guo, Xueming Fan, Xiao Gong, Wenjie Chen, Jing Teng, Jun Tang, Xing Liao, Jingjing Wei, Yunling Zhang

“…ObjectiveThis study aims to develop a COS for future clinical studies on the treatment of TTH with TCM. …”
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Development and validation of a sliding type continuous passive motion automation device for evaluation and rehabilitation of frozen shoulder: a pilot study by Jewoo Lee, Sung-sik Yun, Kyung Rok Oh, Kyung Rok Oh, Sun Gun Chung, Sun Gun Chung, Wonjae Hwang, Wonjae Hwang, Keewon Kim, Keewon Kim, Kyu-jin Cho

“…Pain levels and SPADI scores decreased across all groups, with no statistically significant differences noted between the intervention and the postive control groups.ConclusionsThe developed robotic CPM device demonstrated potential in improving ROM and reducing passive stiffness in FS patients, showing comparable results to therapist-assisted exercise. …”
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Developing an HIV-specific falls risk prediction model with a novel clinical index: a systematic review and meta-analysis method by Sam Chidi Ibeneme, Eunice Odoh, Nweke Martins, Georgian Chiaka Ibeneme

“…Evidence quality and bias were assessed using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) and the Mixed Method Appraisal Tool (MMAT), respectively. …”
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Development and Evaluation of a Patient–Family Caregiver Dyad mHealth Intervention for Heart Failure Self-Care: Quasi-Experimental Study by Youn-Jung Son, JiYeon Choi, Hyue Mee Kim, Hoyoun Won, Jong-Chan Youn, Sang-Wook Kim, Wang-Soo Lee, Jun Hwan Cho, Kyung‑Taek Park, Joonhwa Hong, Da-Young Kim

“…MethodsWe developed a dyadic mHealth program with 2 main features: a basic feature app and an interactive text-based chatbot. …”
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Development of a lung perfusion automated quantitative model based on dual-energy CT pulmonary angiography in patients with chronic pulmonary thromboembolism by Linfeng Xi, Jianping Wang, Anqi Liu, Yifei Ni, Jie Du, Qiang Huang, Yishan Li, Jing Wen, Hongyi Wang, Shuai Zhang, Yunxia Zhang, Zhu Zhang, Dingyi Wang, Wanmu Xie, Qian Gao, Yong Cheng, Zhenguo Zhai, Min Liu

“…Abstract Objective To develop PerAIDE, an AI-driven system for automated analysis of pulmonary perfusion blood volume (PBV) using dual-energy computed tomography pulmonary angiography (DE-CTPA) in patients with chronic pulmonary thromboembolism (CPE). …”
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