Pharmacological and structural characterization of vibostolimab, a novel anti-TIGIT blocking antibody for cancer immunotherapy by Hongmei Wang, Maribel Beaumont, Wendy Blumenschein, Laurence Fayadat-Dilman, Mingmei Cai, Jing Yuan, Douglas Wilson, Thierry O Fischmann, Jeanne Baker, Tanya Keenan, Daniel Malashock, Eunseon Ahn, Komal Pradhan, Jeffery Grein, Srishti Chakravorty, Soheila Bahmanjah, David Ban, Ellen Chien, Mark Hsieh, Todd Mayhood, Janica C Wong, Mark A McCoy, Sybil M G Williams, Wolfgang Seghezzi, Jin-Hwan Han

“…The clinical relevance of vibostolimab, based on these mechanisms, in combination with pembrolizumab was recently tested in registrational trials.…”
Get full text

Exploring meso- and macro-level contextual factors associated with inequalities in program adoption during statewide scale-up of TransformUs Primary, a whole-school physical activi... by Elly Ganakas, Jo Salmon, Jiani Ma, Karen E. Lamb, Lisa Barnett, Adrian Bauman, Amanda Telford, Nicola D. Ridgers, Anna Timperio, Harriet Koorts

Get full text

A Systematic Review and Meta-analysis of the Association Between ACTN3 R577X Genotypes and Performance in Endurance Versus Power Athletes and Non-athletes by El Mokhtar El Ouali, Benjamin Barthelemy, Juan Del Coso, Anthony C. Hackney, Ismail Laher, Karuppasamy Govindasamy, Abdelhalem Mesfioui, Urs Granacher, Hassane Zouhal

“…Results After screening 476 initial registrations, 25 studies were included in the final analysis (13 different countries; 14,541 participants). …”
Get full text