Effectiveness of Kushal Maa, a group-based mhealth interactive education and social support intervention for maternal and neonatal health outcomes: study protocol for a multisite r... by Praveen Kumar, Lakshmi Gopalakrishnan, Nadia Diamond-Smith, Azaz Khan, Abhishek Singh, Rashmi Bagga, Alison M El Ayadi, Anant Bhan, Alka Ahuja, Pushpendra Singh, Mona Duggal, Jasmeet Kaur, Deepak Tugnawat, Tracy Lin, Sujata Saunik, Garima Singh Verma, Shailendrakumar Gujarathi, Dinesh Chandke, Shashi Kant Dhir, Supriya Dhakne-Palwe, Mrunal Patil, Sonam Kumar, Nitin Vasaikar, Laura Weil

“…Results will be published in academic journals and presented at conferences.Trial registration number ClinicalTrials.gov: NCT05268588 Clinical Trials Registry – India: CTRI/2022/07/043889.…”
Get full text

Role of endoscopic ultrasonography in the diagnostic work-up of idiopathic acute pancreatitis (PICUS): study protocol for a nationwide prospective cohort study by Marc G Besselink, Marja A Boermeester, Frank P Vleggaar, Paul Fockens, Marco J Bruno, Hjalmar C van Santvoort, Jeanin E van Hooft, Menno A Brink, Jan-Werner Poley, Robert C Verdonk, Hendrik M van Dullemen, Liesbeth M Kager, Devica S Umans, Hester C Timmerhuis, Nora D Hallensleben, Stefan A Bouwense, Marie-Paule GF Anten, Abha Bhalla, Rina A Bijlsma, Lieke Hol, Wouter L Curvers, Brechje C van Eijck, G Willemien Erkelens, Erwin J M van Geenen, Wouter L Hazen, Chantal V Hoge, Akin Inderson, Sjoerd D Kuiken, Lars E Perk, Rutger Quispel, Tessa EH Römkens, Adriaan CITL Tan, Annemieke Y Thijssen, Niels G Venneman, Annet MCJ Voorburg, Roy LJ van Wanrooij, Ben J Witteman

Get full text

Baseline characteristics of patients with acute ischaemic stroke included in the randomised controlled Find-AF 2 trial by Katrin Wasser, Tobias Uhe, Wolf-Rüdiger Schäbitz, Martin Köhrmann, Martin Dichgans, Johannes Brachmann, Ulrich Laufs, Götz Gelbrich, David Petroff, Christiane Prettin, Dominik Michalski, Johann Pelz, Andrea Kraft, Thorleif Etgen, Hassan Soda, Florian Bethke, Peter D. Schellinger, Katharina Althaus, Gerhard F. Hamann, Martin Grond, Bernd Kallmünzer, Martina Petersen, Lars-Peder Pallesen, Michael Ertl, Philipp Zickler, Sven Poli, Karl Georg Haeusler, Thorsten Steiner, Paul Sparenberg, Pawel Kermer, Anna Kopczak, Lars Kellert, Martin Nückel, Jan Liman, Peter Arthur Ringleb, Meinhard Mende, Marcus Wagner, Deborah Bochert, Marlena Schnieder, Imke Amanzada, Sonja Gröschel, Marianne Hahn, Timo Uphaus, Klaus Gröschel, Rolf Wachter, on behalf of the Find-AF 2 study group

“…The follow-up is ongoing and results are expected within two years. Trial registration ClinicalTrials.gov, Identifier NCT04371055, registered 24 April 2020.…”
Get full text

The effects of computerised decision support systems on nursing and allied health professional performance and patient outcomes: a systematic review and user contextualisation by Carl Thompson, Teumzghi Mebrahtu, Sarah Skyrme, Karen Bloor, Deidre Andre, Anne Maree Keenan, Alison Ledward, Huiqin Yang, Rebecca Randell

“…Higher-quality, theoretically informed, evaluative research that addresses the economics of CDSS development and implementation is still required. Future work Developing nursing CDSS and primary research evaluation. …”
Get full text

Benefits of aldosterone receptor antagonism in chronic kidney disease: the BARACK-D RCT by F D Richard Hobbs, Richard McManus, Clare Taylor, Nicholas Jones, Joy Rahman, Jane Wolstenholme, Louise Jones, Jennifer Hirst, Sam Mort, Ly-Mee Yu

“…Future work These findings might not be applicable to different mineralocorticoid receptor antagonists. Study registration Current Controlled Trials ISRCTN44522369. …”
Get full text

Integrating Palliative Care and Heart Failure: the PalliatHeartSynthesis realist synthesis by Tracey McConnell, Carolyn Blair, Geoff Wong, Claire Duddy, Clare Howie, Loreena Hill, Joanne Reid

“…Our realist analysis developed and refined 6 overarching context–mechanism–outcome configurations and 30 sub context–mechanism–outcome configurations. …”
Get full text

Comparative effectiveness of epilepsy surgery versus additional anti-seizure medications for Lennox–Gastaut syndrome: study protocol for a multicenter, mixed-methods study by Sandi Lam, Sandi Lam, Marc Rosenman, Marc Rosenman, Tracy Dixon-Salazar, Kelly G. Knupp, Liu Lin Thio, Taylor J. Abel, Taylor J. Abel, William P. Welch, William P. Welch, Laurel Reed, Laurel Reed, Stephanie C. Randle, Stephanie C. Randle, Rebecca Garcia-Sosa, Rebecca Garcia-Sosa, Jason S. Hauptman, Carolyn C. Foster, Carolyn C. Foster, Elizabeth R. Alpern, Elizabeth R. Alpern, Lu Zhang, Lu Zhang, Nicole Villalba, Nicole Villalba, Maura Carroll, Anup D. Patel

“…The results of this study may help guide decisions regarding the treatment of LGS and development of computable phenotypes for this rare disease. …”
Get full text

Antitumor immune effects of preoperative sitravatinib and nivolumab in oral cavity cancer: SNOW window-of-opportunity study by David Goldstein, Anna Spreafico, Ilan Weinreb, Trevor J. Pugh, Scott V Bratman, Bayardo Perez-Ordonez, Aaron R Hansen, Lillian Siu, Antony Tin, Alexey Aleshin, Amy Prawira, Jonathan Irish, John de Almeida, Douglas Chepeha, Stephen Smith, Marc Oliva, Daniel V Araujo, J. Javier Diaz-Mejia, Peter Olson, Tina Shek, Andrew Hope, Dax Torti, Jeffrey P. Bruce, Ben X. Wang, Anthony Fortuna, Hirak Der-Torossian, Ronald Shazer, Nickolas Attanasio, Qingyan Au, Jordan Feeney, Himanshu Sethi, Isan Chen

Get full text

PECTIN THERAPY IS A METHOD OF PREVENTION OF REPRODUCTIVE LOSSES ASSOCIATED WITH INTRAPLACENTARY ACCUMULATION OF RADIONUCLIDES by А. Живецька- Денисова, І. Воробйова, Н. Скрипченко, Л. Лозова, О. Шамаєва, Н. Рудакова, С. Стрижак

“…Code VN.20.00.02.18, state registration number 0118U000039, KPKV 6561040. Research results. …”
Get full text

Unveiling biomarkers via plasma metabolome profiling for diabetic macrovascular and microvascular complications by Zhixi Li, Yuhan Ren, Feng Jiang, Kai Zhang, Xuan Meng, Yingfeng Zheng, Mingguang He

“…Trial registration Not applicable.…”
Get full text

Affordable Condominium Housing by Rosa Elena Donoso Gomez

“…Finally it appears that the registration of the policy outcome gives incomplete information for policy evaluation. …”
Get full text

Mixed-methods, descriptive and observational cohort study examining feeding and growth patterns among low birthweight infants in India, Malawi and Tanzania: the LIFE study protocol by Christopher R Sudfeld, Karim Manji, Rodrick Kisenge, Tisungane Mvalo, Melda Phiri, Christopher Duggan, Lauren Spigel, Anne CC Lee, Bethany A Caruso, Laura Subramanian, Megan Marx Delaney, Shivaprasad S Goudar, Linda Vesel, Katherine EA Semrau, Irving F Hoffman, Melissa Young, Friday Saidi, Jnanindra Nath Behera, Roopa M Bellad, Leena Das, Sangappa Dhaded, Gowdar Guruprasad, Sujata Misra, Sanghamitra Panda, Latha G Shamanur, Sunil S Vernekar, Sarah Somji, Linda Adair, Kiersten Israel-Ballard, Stephanie L Martin, Kimberly L Mansen, Krysten North, Emily Benotti, Eliza Fishman, Katelyn Fleming, Natalie Henrich, Kate Miller, Danielle E Tuller

“…The results will be disseminated through peer-reviewed publications and presentations targeting the global and local research, clinical, programme implementation and policy communities.Trial registration numbers NCT04002908 and CTRI/2019/02/017475.…”
Get full text

Retrospective Analysis of Experimental and Clinical Studies of Flakozid in Viral Hepatitis by V. V. Karabaeva, L. V. Krepkova, A. N. Babenko, V. V. Bortnikova, T. V. Fateeva, P. G. Mizina, N. S. Mikheeva, O. N. Karabaeva

“…Viral hepatitis (HV) by its socio-economic significance occupies one of the leading places in human infectious pathology, therefore, the development of fundamentally new methods of prevention, diagnosis and treatment, as well as the creation of new antiviral drugs remain relevant. …”
Get full text

Patterns of antibiotic use, pathogens, and prediction of mortality in hospitalized neonates and young infants with sepsis: A global neonatal sepsis observational cohort study (NeoO... by Neal J Russell, Wolfgang Stöhr, Nishad Plakkal, Aislinn Cook, James A Berkley, Bethou Adhisivam, Ramesh Agarwal, Nawshad Uddin Ahmed, Manica Balasegaram, Daynia Ballot, Adrie Bekker, Eitan Naaman Berezin, Davide Bilardi, Suppawat Boonkasidecha, Cristina G Carvalheiro, Neema Chami, Suman Chaurasia, Sara Chiurchiu, Viviane Rinaldi Favarin Colas, Simon Cousens, Tim R Cressey, Ana Carolina Dantas de Assis, Tran Minh Dien, Yijun Ding, Nguyen Trong Dung, Han Dong, Angela Dramowski, Madhusudhan Ds, Ajay Dudeja, Jinxing Feng, Youri Glupczynski, Srishti Goel, Herman Goossens, Doan Thi Huong Hao, Mahmudul Islam Khan, Tatiana Munera Huertas, Mohammad Shahidul Islam, Daniel Jarovsky, Nathalie Khavessian, Meera Khorana, Angeliki Kontou, Tomislav Kostyanev, Premsak Laoyookhon, Sorasak Lochindarat, Mattias Larsson, Maia De Luca, Surbhi Malhotra-Kumar, Nivedita Mondal, Nitu Mundhra, Philippa Musoke, Marisa M Mussi-Pinhata, Ruchi Nanavati, Firdose Nakwa, Sushma Nangia, Jolly Nankunda, Alessandra Nardone, Borna Nyaoke, Christina W Obiero, Maxensia Owor, Wang Ping, Kanchana Preedisripipat, Shamim Qazi, Lifeng Qi, Tanusha Ramdin, Amy Riddell, Lorenza Romani, Praewpan Roysuwan, Robin Saggers, Emmanuel Roilides, Samir K Saha, Kosmas Sarafidis, Valerie Tusubira, Reenu Thomas, Sithembiso Velaphi, Tuba Vilken, Xiaojiao Wang, Yajuan Wang, Yonghong Yang, Liu Zunjie, Sally Ellis, Julia A Bielicki, A Sarah Walker, Paul T Heath, Mike Sharland

“…We aimed to describe patterns of antibiotic use, pathogens, and clinical outcomes, and to develop a severity score predicting mortality in neonatal sepsis to inform future clinical trial design.…”
Get full text

TASCI—transcutaneous tibial nerve stimulation in patients with acute spinal cord injury to prevent neurogenic detrusor overactivity: protocol for a nationwide, randomised, sham-con... by Lucas M Bachmann, Armin Curt, Patrick Freund, Nikolai Pfender, Martin Schubert, Xavier Jordan, Margret Hund-Georgiadis, Veronika Birkhäuser, Martina D Liechti, Collene E Anderson, Sarah Baumann, Michael Baumberger, Lori A Birder, Sander M Botter, Silvan Büeler, Célia D Cruz, Gergely David, Susanne Friedl, Oliver Gross, Knut Husmann, Miriam Koschorke, Lorenz Leitner, Eugenia Luca, Ulrich Mehnert, Sandra Möhr, Freschta Mohammadzada, Katia Monastyrskaya, Helen Sadri, Andrea M Sartori, Kai Sprengel, Stephanie A Stalder, Jivko Stoyanov, Cornelia Stress, Aurora Tatu, Cécile Tawadros, Stéphanie van der Lely, Jens Wöllner, Veronika Zubler, Jürgen Pannek, Thomas M Kessler

“…Findings will be disseminated through peer-reviewed publications.Trial registration number NCT03965299.…”
Get full text

Clinical characteristics and prognosis of acute stroke in pregnancy and puerperium (ASPP) patients and their offspring: a retrospective, observational, nationwide, multicenter stud... by Zhongji Zhang, Zihan Yin, Tong Liu, Xiaolin Zhang, Qihang Zhang, Junlin Lu, Long Mu, Yang Dong, Juning Liu, Yi Xiao, Yanming Chen, Chenyang Song, Zengguang Wang, Yuheng Liu, Wei Ding, Li Zhang, Huaizhang Shi, Jingtao Qi, Bin Tang, Fei Wang, Pin Guo, Yongjun Tang, Mingsheng Yu, Wenjian Zheng, Qinglong He, Jian Yu, Aihua Zhu, Dazhao Fang, Gang Li, Yu Bai, Yushuang Zhang, Jiaxi Li, Yuli Wang, Faliang Gao, Yonggang Ma, Yifan Liu, Li Ma, Bao Yang, Yahui Zhao, Xun Ye, Qian Zhang, Yan Zhang, Xingju Liu, Jizong Zhao, on behalf of the ASPP Study Group

“…This research may offer new insights into the long-term impacts of pregnancy-related stroke. Trial registration ClinicalTrials.gov (NCT06527807).…”
Get full text

Effectiveness of Chlorthalidone Plus Amiloride for the Prevention of Hypertension: The PREVER‐Prevention Randomized Clinical Trial by Sandra Costa Fuchs, Carlos E. Poli‐de‐Figueiredo, José A. Figueiredo Neto, Luiz César N. Scala, Paul K. Whelton, Francisca Mosele, Renato Bandeira de Mello, José F. Vilela‐Martin, Leila B. Moreira, Hilton Chaves, Marco Mota Gomes, Marcos R. de Sousa, Ricardo Pereira e Silva, Iran Castro, Evandro José Cesarino, Paulo Cesar Jardim, João Guilherme Alves, André Avelino Steffens, Andréa Araujo Brandão, Fernanda M. Consolim‐Colombo, Paulo Ricardo de Alencastro, Abrahão Afiune Neto, Antônio C. Nóbrega, Roberto Silva Franco, Dario C. Sobral Filho, Alexandro Bordignon, Fernando Nobre, Rosane Schlatter, Miguel Gus, Felipe C. Fuchs, Otávio Berwanger, Flávio D. Fuchs

“…The primary outcome was incidence of hypertension. Development or worsening of microalbuminuria, new‐onset diabetes mellitus, and reduction of left ventricular mass were secondary outcomes. …”
Get full text

Effects of pharmacological and non-pharmacological interventions for the management of sleep problems in people with fibromyalgia: a multi-methods evidence synthesis by Mari Imamura, Clare Robertson, Jemma Hudson, Daniel Whibley, Lorna Aucott, Katie Gillies, Marcus Beasley, Martin J Stevens, Paul Manson, Debra Dulake, Abhishek Abhishek, Nicole KY Tang, Gary J Macfarlane, Miriam Brazzelli

“…When possible, for studies that included PROMs originally developed in non-fibromyalgia patients, we consulted the original development study to inform our analysis. …”
Get full text

A mixed methods study protocol for CONFIVAC, an intervention to enhance paediatric nurses' and paediatricians' skills to promote vaccination and vaccine confidence by Elisabet Henderson, Sara Valmayor, Victoria Porthé, Alba Asensio, Xavier Bruna, Usue Elizondo-Alzola, Anna Ramirez-Morros, Gemma Ricós, Josep Vidal-Alaball, M. Isabel Pasarín, Cristina Rius, Elena Roel, Elia Díez

“…By enhancing their skills and confidence, we aim to improve vaccination uptake and streamline vaccine-related tasks in primary care settings.Trial registration: ClinicalTrials ID: NCT06489236…”
Get full text

Systematic review and network meta-analysis with individual participant data on cord management at preterm birth (iCOMP): study protocol by Stuart B Hooper, Peter G Davis, Anup C Katheria, Venkataseshan Sundaram, Lisa Askie, Martin Kluckow, Shigeharu Hosono, Eugene Dempsey, Walid El-Naggar, William Tarnow-Mordi, Heike Rabe, Ronny Knol, Lelia Duley, Thomas Debray, Amir Kugelman, Kellie Murphy, Anna Lene Seidler, Kylie E Hunter, Michael Meyer, Catalina De Paco Matallana, John Kattwinkel, Judith Mercer, Justin Josephsen, Karen Fairchild, Ola Andersson, Vikram Datta, Graeme Polglase, Angie Barba, John Simes, Ava Grace Tan-Koay, Anu George, Anu Sachdeva, Arjan Te Pas, Ashish K C, Bimlesh Kumar, Carl Backes, Chamnan Tanprasertkul, Chayatat Ruangkit, G Ram Mohan, Gillian Gyte, Guillermo Carroli, Heidi Al-Wassia, Hytham Atia, Islam Nour, Jiangqin Liu, John Bauer, Kristy Robledo, Lakhbir Dhaliwal, Laura Perretta, Lin Ling, Manoj Varanattu, Maria Goya, Musa Silahli, Neelam Kler, Neil Finer, Omar Kamlin, Peter Giannone, Pharuhad Pongmee, Prisana Panichkul, Sandeep Kadam, Sangkae Chamnanvanakij, Shiraz Badurdeen, Simone Pratesi, Thomas Ranjit, Victor Lago Leal, Waldemar Carlo

“…Results will be relevant to clinicians, guideline developers and policy-makers, and will be disseminated via publications, presentations and media releases.Registration number Australian New Zealand Clinical Trials Registry (ANZCTR) (ACTRN12619001305112) and International Prospective Register of Systematic Reviews (PROSPERO, CRD42019136640).…”
Get full text