Seropersistence of SII-ChAdOx1 nCoV-19 (COVID-19 vaccine): 6-month follow-up of a randomized, controlled, observer-blind, phase 2/3 immuno-bridging study in Indian adults by Prasad S. Kulkarni, Chandrasekaran Padmapriyadarsini, Johan Vekemans, Ashish Bavdekar, Madhu Gupta, Praveen Kulkarni, B.S. Garg, Nithya J. Gogtay, Muralidhar Tambe, Sanjay Lalwani, Kiranjit Singh, Renuka Munshi, Sushant Meshram, T.S. Selvavinayagam, Krishna Pandey, Devi Madhavi Bhimarasetty, S.R. Ramakrishnan, Chetanraj Bhamare, Abhijeet Dharmadhikari, Chandrashekhar Budhawant, Cyrille J. Bonhomme, Madhuri Thakar, Swarali N. Kurle, Elizabeth J. Kelly, Manish Gautam, Nivedita Gupta, Samiran Panda, Balram Bhargava, Cyrus S. Poonawalla, Umesh Shaligram, Dhananjay Kapse, Bhagwat Gunale

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THE NEED FOR JOINT PLANNING OF ORTHOPEDIC DENTAL CARE IN COMPLEX TREATMENT OF PATIENTS WITH DEFECTS OF MAXILLOFACIAL LOCALIZATION by L.I. Voloshyna, M.G. Skikevych, D.S. Avetikov, V.V. Bondarenko, N.A. Sokolova, V.D. Ahmerov

“…Exchange of information is easily accessible thanks to the development of modern technology in any region of the country. …”
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Advancing the implementation of quality-assured oncological exercise therapy in Germany: protocol for the IMPLEMENT project by Mirko Brandes, Anika Berling-Ernst, Hansjoerg Baurecht, Wiebke Jensen, Miriam Götte, Anne Herrmann, Daniela Fuhr, Heike Schmidt, Antonia Lucas, Bernardine Madl, Simon Elmers, Thorsten Schmidt, Christine Welker, Andre Golla, Annalena Wehner, Dominik Morlok, Jana Rueter, Janina Meuer, Melanie Reitz, Jane Kersten, Rebecca Zimmer, Yvonne Gadczikowske, Renee Stark, Kathrin Hegenberg, Michael Laxy, Martin Halle, Patrick Jahn, Carsten Bokemeyer, Sebastian Theurich, Hajo Zeeb, Michael Leitzmann, Freerk T. Baumann, on behalf of the IMPLEMENT consortium

“…Based on these findings, a set of implementation strategies (IPS) will be developed, implemented, and evaluated to facilitate the delivery of qOET for cancer patients. …”
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Researching COVID to enhance recovery (RECOVER) pediatric study protocol: Rationale, objectives and design. by Rachel S Gross, Tanayott Thaweethai, Erika B Rosenzweig, James Chan, Lori B Chibnik, Mine S Cicek, Amy J Elliott, Valerie J Flaherman, Andrea S Foulkes, Margot Gage Witvliet, Richard Gallagher, Maria Laura Gennaro, Terry L Jernigan, Elizabeth W Karlson, Stuart D Katz, Patricia A Kinser, Lawrence C Kleinman, Michelle F Lamendola-Essel, Joshua D Milner, Sindhu Mohandas, Praveen C Mudumbi, Jane W Newburger, Kyung E Rhee, Amy L Salisbury, Jessica N Snowden, Cheryl R Stein, Melissa S Stockwell, Kelan G Tantisira, Moriah E Thomason, Dongngan T Truong, David Warburton, John C Wood, Shifa Ahmed, Almary Akerlundh, Akram N Alshawabkeh, Brett R Anderson, Judy L Aschner, Andrew M Atz, Robin L Aupperle, Fiona C Baker, Venkataraman Balaraman, Dithi Banerjee, Deanna M Barch, Arielle Baskin-Sommers, Sultana Bhuiyan, Marie-Abele C Bind, Amanda L Bogie, Tamara Bradford, Natalie C Buchbinder, Elliott Bueler, Hülya Bükülmez, B J Casey, Linda Chang, Maryanne Chrisant, Duncan B Clark, Rebecca G Clifton, Katharine N Clouser, Lesley Cottrell, Kelly Cowan, Viren D'Sa, Mirella Dapretto, Soham Dasgupta, Walter Dehority, Audrey Dionne, Kirsten B Dummer, Matthew D Elias, Shari Esquenazi-Karonika, Danielle N Evans, E Vincent S Faustino, Alexander G Fiks, Daniel Forsha, John J Foxe, Naomi P Friedman, Greta Fry, Sunanda Gaur, Dylan G Gee, Kevin M Gray, Stephanie Handler, Ashraf S Harahsheh, Keren Hasbani, Andrew C Heath, Camden Hebson, Mary M Heitzeg, Christina M Hester, Sophia Hill, Laura Hobart-Porter, Travis K F Hong, Carol R Horowitz, Daniel S Hsia, Matthew Huentelman, Kathy D Hummel, Katherine Irby, Joanna Jacobus, Vanessa L Jacoby, Pei-Ni Jone, David C Kaelber, Tyler J Kasmarcak, Matthew J Kluko, Jessica S Kosut, Angela R Laird, Jeremy Landeo-Gutierrez, Sean M Lang, Christine L Larson, Peter Paul C Lim, Krista M Lisdahl, Brian W McCrindle, Russell J McCulloh, Kimberly McHugh, Alan L Mendelsohn, Torri D Metz, Julie Miller, Elizabeth C Mitchell, Lerraughn M Morgan, Eva M Müller-Oehring, Erica R Nahin, Michael C Neale, Manette Ness-Cochinwala, Sheila M Nolan, Carlos R Oliveira, Onyekachukwu Osakwe, Matthew E Oster, R Mark Payne, Michael A Portman, Hengameh Raissy, Isabelle G Randall, Suchitra Rao, Harrison T Reeder, Johana M Rosas, Mark W Russell, Arash A Sabati, Yamuna Sanil, Alice I Sato, Michael S Schechter, Rangaraj Selvarangan, S Kristen Sexson Tejtel, Divya Shakti, Kavita Sharma, Lindsay M Squeglia, Shubika Srivastava, Michelle D Stevenson, Jacqueline Szmuszkovicz, Maria M Talavera-Barber, Ronald J Teufel, Deepika Thacker, Felicia Trachtenberg, Mmekom M Udosen, Megan R Warner, Sara E Watson, Alan Werzberger, Jordan C Weyer, Marion J Wood, H Shonna Yin, William T Zempsky, Emily Zimmerman, Benard P Dreyer, RECOVER-Pediatric Consortium

“…<h4>Clinical trials.gov identifier</h4>Clinical Trial Registration: http://www.clinicaltrials.gov. Unique identifier: NCT05172011.…”
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Homologous recombination deficiency (HRD) tests for ovarian cancer: a multicenter French phase II study (HERO) by Raphaël Leman, François Cherifi, Marianne Leheurteur, Pierrick Theret, Camille Pasquesoone, Mathilde Saint-Ghislain, Lucie Bresson, Christophe Denoyelle, Nicolas Vigneron, Laurent Poulain, Raphaël Delepee, Benoit Berby, Julie Dremaux, Aurélie Dumont, Cécile Blanc-Fournier, Corinne Jeanne, Mélanie Briand, Nathalie Rousseau, Louis-Ferdinand Pepin, Elodie Deruche, Fabienne Dumont, Alexandra Leconte, Justine Lequesne, Bénédicte Clarisse, Florence Joly, Laurent Castera, Roman Rouzier

“…To fulfil these challenges, our laboratory has recently developed a HRD test named GIScar (Genomic Instability Scar). …”
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What happens between first symptoms and first acute exacerbation of COPD – observational study of routine data and patient survey by Alex Bottle, Alex Adamson, Xiubin Zhang, Benedict Hayhoe, Jennifer K Quint

“…Study registration This study is registered as Researchregistry.com: researchregistry4762. …”
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The use of “Acellbia” – a biosimilar of rituximab in systemic sclerosis by L. P. Ananyeva, L. A. Garzanova, O. V. Desinova, R. U. Shayakhmetova, M. N. Starovoytova, O. A. Koneva, O. B. Ovsyannikova, S. I. Glukhova, E. L. Nasonov

“…One patient developed calf vein thrombosis and lung cancer was diagnosed in one case.Conclusion. …”
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Protocol for a cluster randomised trial evaluating a multifaceted intervention starting preconceptionally—Early Interventions to Support Trajectories for Healthy Life in India (EIN... by Mary Barker, Janis Baird, K S Joseph, Cindy-Lee Dennis, Zulfiqar A Bhutta, Prakesh S Shah, Saumyadipta Pyne, Nalini Singhal, Murali Krishna, Prabhat Jha, Harshpal Singh Sachdev, Kalyanaraman Kumaran, Caroline H D Fall, Stephanie Atkinson, Stephen Lye, Stephen G Matthews, Daniel Sellen, Ghattu V Krishnaveni, Kumar Gavali Suryanarayana, Manohar Prabhu Prasad, Antonisamy Belavendra, Ramaswamy Balasubramaniam, Robert H J Bandsma, Giriraj Ratan Chandak, Elena M Comelli, Sandra T Davidge, Geoffrey L Hammond, Sadhana R Joshi, Kang Lee, Patrick McGowan, Pablo Nepomnaschy, Vivek Padvetnaya, Sirazul Ameen Sahariah, Jacquetta Trasler, Chittaranjan S Yajnik, Marie-Claude Martin, Nusrat Husain

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Climate footprint of industry-sponsored in-human clinical trials: life cycle assessments of clinical trials spanning multiple phases and disease areas by Michael Collins, Thomas Costelloe, Jason Keith LaRoche, Rodrigo Alvarenga, Wouter De Soete, Jeremy Faludi, Kristel Rens, Jason Lanier, Annemie Chiau, Hugh Whetherly

“…Across the multisite phase 2, 3 and 4 trials we analysed, a combination of the observed five largest contributors to GHG emissions were responsible for no less than 79% of GHG emissions for any one trial.Conclusions Based on our LCAs of seven clinical trials spanning all four phases of development and multiple disease areas, there are five activities that drive no less than 79% of the average clinical trial’s GHG footprint. …”
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Supporting African communities to increase resilience and mental health of kids with developmental disabilities and their caregivers using the World Health Organization’s Caregiver... by Melissa Washington-Nortey, Vibian Angwenyi, Mekdes Demissie, Eva Mwangome, Tigist Eshetu, Hanna Negussie, Kimberley Goldsmith, Andrew Healey, Merga Feyasa, Girmay Medhin, Amanuel Belay, Temesgen Azmeraw, Medhanit Getachew, Rahel Birhane, Carophine Nasambu, Tsegereda Haile Kifle, Angela Kairu, Beatrice Mkubwa, Fikirte Girma, Rehana Abdurahman, Ruth Tsigebrhan, Liya Tesfaye, Leonard Mbonani, Nadine Seward, Tony Charman, Andrew Pickles, Erica Salomone, Chiara Servili, Edwine Barasa, Charles R. Newton, Charlotte Hanlon, Amina Abubakar, Rosa A. Hoekstra

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GUIDE: a prospective cohort study for blood-based early detection of gastrointestinal cancers using targeted DNA methylation and fragmentomics sequencing by Ao Huang, De-Zhen Guo, Zhi-Xi Su, Yun-Shi Zhong, Liang Liu, Zhi-Guo Xiong, Dong-Li He, Bin Yan, Quan-Lin Li, Zhen Feng, Wen-Quan Wang, Pin-Xiang Lu, Meng-Jiang He, Zhi-Peng Qi, Qi Guo, Jian-Wen Cheng, Shi-Yu Zhang, Wei Guo, Qing Li, Guo-Yong Lin, Hui-Chuan Sun, Shuang-Jian Qiu, Qi-Ye He, Jia Fan, Ajay Goel, Rui Liu, Gang Jin, Xin-Rong Yang, Jian Zhou

“…To address this clinical need, we developed GutSeer, a blood-based assay combining DNA methylation and fragmentomics for multi-GI cancer detection. …”
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Investigation of the use of a sensor bracelet for the presymptomatic detection of changes in physiological parameters related to COVID-19: an interim analysis of a prospective coho... by Stefanie Aeschbacher, David Conen, Diederick E Grobbee, Raphael Twerenbold, Thomas Lung, Theo Rispens, Jakob Kjellberg, Lorenz Risch, Martin Risch, Marianna Mitratza, Harald Renz, Spiros Denaxas, Billy Franks, Diederick Grobbee, Martina Rothenbühler, Janneke Wijgert, Santiago Montes, Richard Dobson, Hans Reitsma, Christian Simon, Titia Leurink, Charisma Hehakaya, Patricia Bruijning, Kirsten Grossmann, Ornella C Weideli, Marc Kovac, Fiona Pereira, Nadia Wohlwend, Corina Risch, Dorothea Hillmann, Daniel Leibovitz, Vladimir Kovacevic, Andjela Markovic, Paul Klaver, Timo B Brakenhoff, George S Downward, Ariel Dowling, Maureen Cronin, Brianna M Goodale, Brianna Goodale, Ornella Weideli, Regien Stokman, Hans Van Dijk, Eric Houtman, Jon Bouwman, Kay Hage, Lotte Smets, Marcel van Willigen, Maui Chodura, Niki de Vink, Tessa Heikamp, Timo Brakenhoff, Wendy van Scherpenzeel, Wout Aarts, Alison Kuchta, Antonella Chiucchiuini, Steve Emby, Annemarijn Douwes, George Downward, Nathalie Vigot, Pieter Stolk, Duco Veen, Daniel Oberski, Amos Folarin, Pablo Fernandez Medina, Eskild Fredslund

“…Our proposed RNN algorithm identified 68% of COVID-19 positive participants 2 days prior to SO and will be further trained and validated in a randomised, single-blinded, two-period, two-sequence crossover trial.Trial registration numberISRCTN51255782; Pre-results.…”
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Patterns of Postablation Recurrence and Adverse Cardiovascular Outcomes in Patients With Atrial Fibrillation by Sitong Li, Jingrui Zhang, Song Zuo, Jue Wang, Yiwei Lai, Mingxiao Li, Zejun Yang, Zixu Zhao, Manlin Zhao, Lan Ren, Zhen Wang, Chao Jiang, Liu He, Xueyuan Guo, Xiaoxia Liu, Ribo Tang, Ning Zhou, Caihua Sang, Deyong Long, Xin Du, Jianzeng Dong, Changsheng Ma

“…Conclusions Postablation PersAF recurrence was associated with significantly higher risks of cardiovascular death and thromboembolism, compared with paroxysmal AF recurrence and nonrecurrence, indicating the prognostic importance of recurrence patterns. Registration URL: www.chictr.org.cn/; unique identifier: ChiCTR‐OCH‐13003729.…”
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CD22-targeted chimeric antigen receptor-modified T cells for children and adults with relapse of B-cell acute lymphoblastic leukemia after CD19-directed immunotherapy by Clare Taylor, Carl H June, Joseph A Fraietta, Boris Engels, Gabriela Plesa, Marco Ruella, Stephan A Grupp, Hongyan Liu, Colleen Callahan, Shannon L Maude, Regina M Myers, Caroline Diorio, Yimei Li, Vanessa Gonzalez, Julie K Jadlowsky, Amanda M DiNofia, Gerald Wertheim, Donald L Siegel, Emma Iannone, Laura Shinehouse, Jennifer L Brogdon, Elizabeth O Hexner, Diane Baniewicz, Richard Aplenc, Allison Barz Leahy, Susan E McClory, Susan R Rheingold, Lisa Wray, Noelle V Frey

“…In vivo cellular kinetic data revealed robust CART22-65s proliferation by quantitative PCR peaking at a median of 20 days postinfusion, with the cells persisting out to month 42 in one patient who achieved a long-term remission with CART22-65s alone.Conclusions The favorable safety profile and high remission rates in exceedingly refractory B-ALL support the continued development of CART22-65s but also highlight the need to use the product in combination with HCT or other novel strategies.Trial registration numbers NCT02650414 and NCT03620058.…”
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Analytical treatment interruption among women with HIV in southern Africa who received VRC01 or placebo in the Antibody Mediated Prevention Study: ATI stakeholder engagement, imple... by Shelly Karuna, Fatima Laher, Sufia Dadabhai, Pei‐Chun Yu, Doug Grove, Catherine Orrell, Joseph Makhema, Mina C. Hosseinipour, Carrie‐Anne Mathew, William Brumskine, Nyaradzo Mgodi, Philip Andrew, Lucio Gama, Carissa Karg, Gail Broder, Kagisho Baepanye, Jonathan Lucas, Michele Andrasik, Simbarashe Takuva, Manuel Villaran, Azwidihwi Takalani, Randall Tressler, Lydia Soto‐Torres, Amanda S. Woodward Davis, Ames Dhai, Ian M. Sanne, Myron S. Cohen, Lawrence Corey, Glenda Gray, Allan C. deCamp, Katharine J. Bar

“…Clinical Trial Registration NCT04860323…”
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Circadian rhythm dysfunction and psychopathology in the offspring of parents with bipolar disorder: a high-risk study in the Chinese population by Jing Wang, Tao Li, Yun Kwok Wing, Jihui Zhang, Jie Chen, Bin Zhang, Weidong Song, Chao Jiang, Jiyang Pan, Kun Zhang, Yaping Liu, Ngan Yin Chan, Hongliang Feng, Lulu Yang, Binbin Lei, Qunfeng Wang, Jessie Chi Ching Tsang, Joey W.Y. Chan, Kathleen Ries Merikangas

“…The findings of the specific age-related and stage-related developmental patterns of psychopathologies and circadian dysfunction in children and adolescent offspring of parents with bipolar disorder paved the way to develop specific and early clinical intervention and prevention strategies.Trial registration number NCT03656302.…”
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Effects of a liquefied petroleum gas stove and fuel intervention on head circumference and length at birth: A multi-country household air pollution intervention network (HAPIN) tri... by Hina Raheel, Sheela Sinharoy, Anaité Diaz-Artiga, Sarada S. Garg, Ajay Pillarisetti, Kalpana Balakrishnan, Marilu Chiang, Amy Lovvorn, Miles Kirby, Usha Ramakrishnan, Shirin Jabbarzadeh, Alexie Mukeshimana, Michael Johnson, John P. McCracken, Luke P. Naeher, Ghislaine Rosa, Jiantong Wang, Joshua Rosenthal, William Checkley, Thomas F. Clasen, Jennifer L. Peel, Lisa M. Thompson

“…Background: Air pollution may impair child growth and cognitive development, with potential markers including birth length and head circumference. …”
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Global HPV vaccination programs and coverage rates: a systematic reviewResearch in context by Jingjing Han, Li Zhang, Yuqing Chen, Yuelun Zhang, Le Wang, Ruyu Cai, Minge Li, Yuxin Dai, Le Dang, Hongda Chen, Lan Zhu

“…Strategies to effectively enhance HPV vaccination coverage must be identified, developed, and implemented to address this gap. Funding: CAMS Innovation Fund for Medical Sciences (2021-I2M-1–004, 2023-I2M-3-019); National High Level Hospital Clinical Research Funding (2022-PUMCH-D-003); Supported by Sanming Project of Medicine in Shenzhen (SZSM202311011).…”
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Adherence to Physical Activity and Incident Mobility Disability in Older Adults With Mobility Limitations by Alejandro Álvarez‐Bustos, Helio José Coelho‐Junior, Riccardo Calvani, Leocadio Rodriguez‐Mañas, Matteo Tosato, Matteo Cesari, Antonio Cherubini, Alfonso J. Cruz‐Jentoft, Pálmi V. Jónsson, Fabrizia Lattanzio, Marcello Maggio, Regina Roller‐Wirnsberger, Ingrid Rýznarová, Annemie M. W. J. Schols, Cornel C. Sieber, Alan J. Sinclair, Anna Skalska, Timo Strandberg, Achille Tchalla, Eva Topinková, Bruno Vellas, Stephan vonHaehling, Francesco Landi, Emanuele Marzetti, for the SPRINTT consortium

“…This benefit depends on the degree of adherence as well as baseline physical performance. Trial Registration: ClinicalTrials.gov NCT02582138…”
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A peer-support lifestyle intervention for preventing type 2 diabetes in India: A cluster-randomized controlled trial of the Kerala Diabetes Prevention Program. by Kavumpurathu R Thankappan, Thirunavukkarasu Sathish, Robyn J Tapp, Jonathan E Shaw, Mojtaba Lotfaliany, Rory Wolfe, Pilvikki Absetz, Elezebeth Mathews, Zahra Aziz, Emily D Williams, Edwin B Fisher, Paul Z Zimmet, Ajay Mahal, Sajitha Balachandran, Fabrizio D'Esposito, Priyanka Sajeev, Emma Thomas, Brian Oldenburg

“…After a median follow-up of 24 months, diabetes developed in 17.1% (79/463) of control participants and 14.9% (68/456) of intervention participants (relative risk [RR] 0.88, 95% CI 0.66-1.16, p = 0.36). …”
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