BMI matters: understanding the link between weight and severe psoriasis by Huiwei Wang, Suchun Hou, Xiaojing Kang, Chen Yu, Bin Yang, Yuling Shi, Fuqiu Li, Wei Li, Jun Gu, Mingjun Lei, Youkun Lin, Gang Wang, Hongzhong Jin, Xiaoming Liu

“…Clinicaltrials.gov: ChiCTR1900024852, date of registration: 2019-07-31.…”
Get full text

In-person vs mobile app facilitated life skills education to improve the mental health of internally displaced persons in Nigeria: protocol for the RESETTLE-IDPs cluster randomized... by Ejemai Eboreime, Chisom Obi-Jeff, Rita Orji, Tunde M Ojo, Ihoghosa Iyamu, Bala I Harri, Jidda M Said, Funmilayo Oguntimehin, Abdulrahman Ibrahim, Omolayo Anjorin, Andem Effiong Etim Duke, Umar Baba Musami, Linda Liebenberg, Raquel Crider, Lydia Wagami, Asmau MC Dahiru, Jesse C. Uneke, Sanni Yaya, Vincent IO Agyapong

“…Trial sponsor Dalhousie University, 6299 South St, Halifax, NS B3H 4R2, Canada. Trial registration ClinicalTrials.gov, NCT06412679  Registered 15 May 2024.…”
Get full text

Effect of opioid-free anaesthesia on postoperative delirium in elderly patients undergoing gastrointestinal surgery: study protocol for a single-centre, prospective, randomized con... by Yuehan Du, Mengjie Liu, Xiaoling Yang, Jianbo Wu, Xiaojun Gao, Qiuyue Liu, Lina Chen, Xiaxuan Sun, Min Zhang, Yongtao Sun

“…This study aims to investigate the effects of OFA on the development of POD in elderly patients following gastrointestinal surgery. …”
Get full text

Improvement of neuropsychological and cognitive functions in older adults through transcranial vibroacoustic stimulation: a double blind, randomized, comparative trial by Jang-Han Bae, Jang-Han Bae, Jae-Young Ha, Jai Jun Choung, Min-Woo Cho, Byung-In Oh, Kun Ho Lee, Kun Ho Lee, Young Chul Youn, SangYun Kim, Dong-Keun Song, Chang-Ho Shin, Chang-Ho Shin

“…Recent research has focused on developing non-invasive methods for cognitive enhancement with the potential to slow cognitive decline. …”
Get full text

Evaluating the psychometric measurement properties of patient-reported outcome measures for uterine fibroids using the Consensus-based Standards for the selection of health Measure... by Wei Yan, Fei Liu, Ya Li, Shixuan Wang, Minli Zhang, Wenwen Wang, Suzhen Yuan, Shuhao Yang, Qing Yan, Tao Xiang

“…The UFS-QoL and BPD were classified as ‘A’ and were recommended, demonstrating the potential to promote outcome measurements in future studies.PROSPERO registration number CRD42023474806.…”
Get full text

Medicines support and social prescribing to address patient priorities in multimorbidity (MIDAS): protocol for a definitive, multi-arm, cluster randomised, controlled trial in Iris... by Susan M Smith, Fiona Boland, Frank Moriarty, Molly Byrne, Farah Tahsin, Barbara Clyne, Paul Doody, Laura O’Connor, Paddy Gillespie, Bridget Kiely, Andrew W Murphy, Eanna Kenny

“…A formal knowledge dissemination plan has been developed for the trial, which includes peer-reviewed publications, conference presentations and reports to healthcare professionals, commissioners and policymakers.Trial registration number ISRCTN11585238.…”
Get full text

Flow cytometric lyophilised reagent tube assay for peripheral blood neutrophil myeloperoxidase expression to rule out myelodysplastic neoplasms at a university hospital: a diagnost... by Sophie Park, José Labarère, Arnaud Seigneurin, Lysiane Molina, Raymond Merle, Tatiana Raskovalova, Laura Scheffen, Marie-Christine Jacob, Simon Chevalier, Sylvie Tondeur, Bénédicte Bulabois, Mathieu Meunier, Gautier Szymanski, Christine Lefebvre, Charlotte Planta, Nicolas Gonnet, Frédéric Garban, Radu Chiriac, Claire Paradis

“…It may obviate the need for invasive bone marrow aspiration in up to 40% of patients with suspected MDS.Trials registration number NCT04399018.…”
Get full text

The comparative evidence of efficacy of non-invasive brain and nerve stimulation in diabetic neuropathy: a systematic review and network meta-analysis by Ping-Tao Tseng, Bing-Yan Zeng, Chih-Wei Hsu, Chao-Ming Hung, Brendon Stubbs, Yen-Wen Chen, Tien-Yu Chen, Jiann-Jy Chen, Wei-Te Lei, Yow-Ling Shiue, Chih-Sung Liang

“…Future well-designed RCTs with longer treatment durations are recommended to further validate the long-term efficacy of these interventions. Trial registration PROSPERO CRD42024587660.…”
Get full text

The Vertebral Bone Marrow clot as cell therapy and multifunctional bioscaffold for spinal fusion surgery: protocol for a randomized clinical trial by Maria Sartori, Giuseppe Tedesco, Paolo Spinnato, Antonio Mazzotti, Antonio Mazzotti, Alessandro Gasbarrini, Alessandro Gasbarrini, Cesare Faldini, Cesare Faldini, Marco Miceli, Gianluca Giavaresi, Francesca Salamanna

“…Among these, Vertebral Bone Marrow Aspirate (vBMA) clot emerges as an innovative and promising avenue for future development. The primary challenge in using vBMA clot for SF procedures lies in the lack of high-level clinical evidence demonstrating whether its combination with bone allograft chips is superior to using bone allograft chips alone. …”
Get full text

Students’ motives for enrolling in the master of nursing program in Croatia despite degree recognition uncertainties: a cross-sectional study by Andrea Vuksa, Vesna Mijoc, Ivica Matic, Marta Civljak, Marin Cargo, Snježana Cukljek, Kata Ivanisevic, Mario Marendic, Zrinka Puharic, Natasa Skitarelic, Sanja Zoranic, Marijana Neuberg, Dijana Majstorovic, Alen Brecek, Ivana Barac, Livia Puljak

“…Aligning Croatia’s educational and healthcare systems to recognize and utilize MN graduates effectively could strengthen the nation’s healthcare workforce. Clinical trial registration Not applicable. This study was not a clinical trial.…”
Get full text

Supportive supervision visits in a large community hypertension programme in Nigeria: implementation methods and outcomes by Mark D Huffman, Dike Ojji, Lisa Hirschhorn, Namratha R Kandula, Eugenia N Ugwuneji, Gabriel Lamkur Shedul, Boni M Ale, Nanna Ripiye, Erica L Jamro, Ikechukwu A Orji, Grace Julcit Shedul, Emmanuel Okpetu, Samuel Osagie, Abigail S Baldridge

“…This approach can be modelled for supporting HEARTS implementation in other settings.Trial registration number The trial was prospectively registered at www.clinicaltrials.gov under NCT04158154 on 8 November 2019; https://clinicaltrials.gov/ct2/show/NCT04158154.…”
Get full text

Patient Voices: Multimethod Study on the Feasibility of Implementing Electronic Patient-Reported Outcome Measures in a Comprehensive Cancer Center by Cinzia Brunelli, Sara Alfieri, Emanuela Zito, Marco Spelta, Laura Arba, Linda Lombi, Luana Caselli, Augusto Caraceni, Claudia Borreani, Anna Roli, Rosalba Miceli, Gabriele Tine', Ernesto Zecca, Marco Platania, Giuseppe Procopio, Nicola Nicolai, Luigi Battaglia, Laura Lozza, Morena Shkodra, Giacomo Massa, Daniele Loiacono, Giovanni Apolone

“… Background“Patient Voices” is a software developed to promote the systematic collection of electronic patient-reported outcome measures (ePROMs) in routine oncology clinical practice. …”
Get full text

Safety and feasibility of allogeneic cord blood-derived cell therapy in preterm infants with severe brain injury (ALLO trial): a phase-1 trial protocol by Atul Malhotra, Lin Liu, Abdul Razak, Rod W Hunt, Suzanne L Miller, Graham Jenkin, Michelle Martin, Kristyn Connelly, Courtney A McDonald, Lindsay Zhou, Madison CB Paton, Cathie Hart, Ngaire J Elwood

“…Findings will be disseminated through peer-reviewed publications and conference presentations, contributing to the development of novel neuroreparative therapies for preterm brain injury.Trial registration number ACTRN12623001352695 (The Australian New Zealand Clinical Trials Registry).…”
Get full text

Access and use of general and mental health services before and during the COVID-19 pandemic: a systematic review and meta-analysis by Marianna Purgato, Federico Tedeschi, Corrado Barbui, Emiliano Albanese, Eleonora Prina, Beatrice Bano, Camilla Sculco, Monica Bianca Bartucz

“…We observed significant differences in effect sizes across studies (τ2=5.44; p<0.001 and τ2=0.090; p<0.001).Conclusion By considering MH, our study provides consolidated evidence and quantifies the reduction in the use of health services during the COVID-19 pandemic.PROSPERO registration number CRD42023403778.…”
Get full text

Evaluating SinergiAPS, an intervention based on patient feedback to improve patient safety in primary care: a cluster randomized trial by Maria Antònia Fiol-deRoque, José María Valderas, María Jesús Serrano-Ripoll, Montserrat Gens-Barbarà, Francisco Martín-Luján, Encarna Sánchez-Freire, Juan José Montaño, Sofía Mira-Martínez, Guadalupe Pastor-Moreno, Rocío Zamanillo-Campos, Pau Riera-Serra, Ignacio Ricci-Cabello

“…Conclusions In the context of the health emergency caused by the COVID-19 pandemic, SinergiAPS did not improve patient safety in Spanish PHC centres. Trial registration ClinicalTrials.gov (NCT03837912).…”
Get full text

Prevalence and associated factors of chronic pain among nurses: a national cross-sectional study by Zhenhui Ren, Jiaxin Yang, Chongmei Huang, Qiang Yu, Xuting Li, Zengyu Chen, Dan Zhang, Chunhui Bin, Meng Ning, Yiting Liu, Jianghao Yuan, Yamin Li, Yusheng Tian

“…Abstract Background Musculoskeletal pain is common among nurses and can lead to absenteeism, reduced productivity and impaired physical and mental health. Long-term pain may develop into chronic pain, which is a more serious and longer-lasting condition that will cause further harm to nurses’ health. …”
Get full text

The Comprehensive Adaptive Multisite Prevention of University Student Suicide Trial: Protocol for a Randomized Controlled Trial by Kyla Blalock, Jacqueline Pistorello, Shireen L Rizvi, John R Seeley, Francesca Kassing, James Sinclair, Linda A Oshin, Robert J Gallop, Cassidy M Fry, Ted Snyderman, David A Jobes, Jennifer Crumlish, Hannah R Krall, Susan Stadelman, Filiz Gözenman-Sapin, Kate Davies, David Steele, David B Goldston, Scott N Compton

“…ObjectiveThe Comprehensive Adaptive Multisite Prevention of University Student Suicide (CAMPUS) Trial evaluates 4 treatment sequences within UCCs to develop evidence-based treatment guidelines. …”
Get full text

Layer-by-Layer Multifractal Scanning of Optically Anisotropic Architectonics of Blood Plasma Films: Fundamental and Applied Aspects by Alexander Ushenko, Natalia Pavlyukovich, Oksana Khukhlina, Olexander Pavlyukovich, Mykhaylo Gorsky, Iryna Soltys, Alexander Dubolazov, Yurii Ushenko, Olexander Salega, Ivan Mikirin, Jun Zheng, Zhebo Chen, Lin Bin

“…In the proposed model, algorithms were developed to relate the real and imaginary parts of the complex elements of the Jones matrix to the theziograms of linear and circular birefringence. …”
Get full text

Cost-effectiveness analysis of the Assessment of Burden of Chronic Conditions (ABCC) tool in primary care in the Netherlands by Manuela A Joore, Esther A Boudewijns, Mascha Twellaar, Onno CP van Schayck, Merel L Kimman, Loraine HL Peters, Annerika HM Gidding-Slok, Lotte CEM Keijsers, Jean WM Muris

“…The per-protocol analysis suggested that the ABCC tool can be cost-effective when actually used.Trial registration number NCT04127383.…”
Get full text

Evaluating the performance of an automated respiratory rate counter in detecting fast breathing pneumonia in children using a reference video expert panel by Ahad Mahmud Khan, Md Shafiqul Islam, Nabidul Haque Chowdhury, Salahuddin Ahmed, Rezwana Tabassum, Sadia Afrin, Zannatul Ferdush Amin, Kazi Sazzadul Haque, Afroza Yeasmin Rumi, Jawata Rahman, Rakib Bhuiyan, Rizouan Ur Rashid, Kamrun Nahar, Robynne Simpson, Ayaz Ahmed, Md Mozibur Rahman, Ting Shi, Abdullah H. Baqui, Steve Cunningham, Eric D. McCollum, Harry Campbell

“…To address this gap, we introduced an automated RR counter and developed a reference video expert panel (VEP) to evaluate its performance. …”
Get full text