Real-world evaluation of prevalence, cohort characteristics, and healthcare utilization and expenditures among adults and children with autism spectrum disorder, attention-deficit... by Amanda L. Zaleski, Kelly J. Thomas Craig, Raiha Khan, Rebecca Waber, Wei Xin, Makia Powers, Una Ramey, Dorothea J. Verbrugge, Deborah Fernandez-Turner

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Behavioural components and delivery features of early childhood obesity prevention interventions: intervention coding of studies in the TOPCHILD Collaboration systematic review by Brittany J. Johnson, Paul M. Chadwick, Samantha Pryde, Anna Lene Seidler, Kylie E. Hunter, Mason Aberoumand, Jonathan G. Williams, Hei In Lau, Sol Libesman, Jannik Aagerup, Angie Barba, Louise A. Baur, Samantha Morgillo, Lee Sanders, Sarah Taki, Kylie D. Hesketh, Karen Campbell, Alexandra Manson, Alison Hayes, Angela Webster, Charles Wood, Denise A. O’Connor, Karen Matvienko-Sikar, Kristy Robledo, Lisa Askie, Luke Wolfenden, Rachael Taylor, H. Shonna Yin, Vicki Brown, Alexander Fiks, Alison Ventura, Ata Ghaderi, Barry J. Taylor, Cathleen Stough, Christine Helle, Cristina Palacios, Eliana M. Perrin, Elizabeth Reifsnider, Finn Rasmussen, Ian M. Paul, Jennifer S. Savage, Jessica Thomson, Jinan Banna, Junilla Larsen, Kaumudi Joshipura, Ken K. Ong, Levie Karssen, Li Ming Wen, Márcia Vitolo, Margrethe Røed, Maria Bryant, Maribel Campos Rivera, Mary Jo Messito, Natalia Golova, Nina Cecilie Øverby, Rachel Gross, Rajalakshmi Lakshman, Rebecca Byrne, Russell L. Rothman, Sharleen O’Reilly, Stephanie Anzman-Frasca, Vera Verbestel, Claudio Maffeis, Kayla de la Haye, Sarah-Jeanne Salvy, Seema Mihrshahi, Janani Ramachandran, Paola Seffrin Baratto, Rebecca K. Golley, on behalf of the TOPCHILD Collaboration

“…These findings can be used to examine effectiveness of components and inform intervention development and evaluation in future trials. Trial registration PROSPERO registration no. …”
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Glucose metabolism after distal pancreatectomy - deterioration of beta cell function becomes noticeable at an early stage: a retrospective cohort study by Mikheil Kalandarishvili, Florian Oehme, Olga Radulova-Mauersberger, Nicole Kipke, Michele Solimena, Christian Teske, Nicolas Mibelli, Jürgen Weitz, Marius Distler, Sebastian Hempel

“…If possible parenchymal sparing surgical options should be contemplated. Trial registration Not applicable.…”
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Modifying exercise and physical therapy in medical rehabilitation to promote a physically active lifestyle: Protocol for a multicenter controlled hybrid type 2 effectiveness-implem... by Eva Grüne, Johannes Carl, Wolfgang Geidl, Johanna Popp, David Victor Fiedler, Natalie Boss, Regina Brinkmann, Juliane von dem Bussche, Gabi Eichner, Kathrin Kleinert, Christoph Löhr, Florian Mex, Paul Schwanitz von Keitz, Till Richter, Joachim Schmidt, Rainer Tischendorf, Gorden Sudeck, Klaus Pfeifer

“…Methods As part of the STABEKO study, we will use cooperative planning as a co-creation approach for planning, developing, and implementing actions to modify exercise and physical therapy by engaging relevant actors from practice, policy, and research in an equal decision-making process. …”
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Tebipenem pivoxil as an alternative to ceftriaxone for clinically non-responding children with shigellosis: a randomised non-inferiority trial protocol by Subhasish Das, Tahmeed Ahmed, Juliet Addo, Firdausi Qadri, Rachel Gibson, Patricia B Pavlinac, Md Jobayer Chisti, Farhana Khanam, Dilruba Ahmed, Sharika Nuzhat, Md Ridwan Islam, Syed Jayedul Bashar, Samuel L Arnold, Amy Newlands, Elena Fernandez Alvaro

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Longitudinal plasma amino acids during pregnancy and neonatal anthropometry: findings from the NICHD Fetal Growth Studies-Singleton Cohort by Claire Guivarch, Jing Wu, Ruijin Lu, Jagteshwar Grewal, Guoqi Yu, Ling-Jun Li, Jiaxi Yang, Wei Wei Pang, Dong D. Wang, Natalie L. Weir, Zhen Chen, Michael Y. Tsai, Cuilin Zhang

“…Associations were observed as early as 10 GW and varied by type of AAs and gestational age. Trial registration Clinical Trial Registry number: NCT 00912132.…”
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Evidence adaptation and tailored implementation of family bereavement support in specialised palliative care: A multi-method study by Myrta Kohler, Qëndresa Thaqi, Silke Kuske, Torsten Schwalbach, Marco Riguzzi, Rahel Naef

“…Adapting evidence to specific contexts and understanding potential barriers and facilitators is necessary to prepare implementation. Registration: https://osf.io/qgr7y…”
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Effectiveness of care coordination interventions delivered to stroke survivors in low and middle-income countries: Systematic review and meta-analysis protocol. by Stephanopoulos Kofi Junior Osei, Anthony Danso-Appiah

“…Study selection will be done using a study selection flow chart developed from the pre-specified eligibility criteria defined by the PICOS elements (P ─ patient, I ─ intervention, C ─ comparator, O ─ outcomes and S ─study). …”
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How do we measure dysarthria after stroke? A systematic review to guide the core outcome set for dysarthria by Jamie J Kirkham, Claire Mitchell, Audrey Bowen, Joshua Cheyne, Paul Conroy, Sabrina El Kouaissi, Martha Duncan-Zaleski, Brooke-Mai Whelan, Sarah J Jane Wallace

“…There is a need for further psychometric testing of these and the development of new measurement instruments to cover all aspects of intelligibility, conversations, living well with dysarthria and communication partner skills.PROSPERO registration number CRD42022302998.…”
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Effects of the Informed Health Choices secondary school intervention on the ability of lower secondary students in Kenya to think critically about health choices: 1-year follow-up... by Faith Chesire, Margaret Kaseje, Violet Gisore, Michael Mugisha, Ronald Ssenyonga, Matt Oxman, Allen Nsangi, Daniel Semakula, Christopher James Rose, Laetitia Nyirazinyoye, Simon Lewin, Nelson K. Sewankambo, Sarah Rosenbaum, Jenny Moberg, Andrew D. Oxman

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Frontal Pole Neuromodulation for Impulsivity and Suicidality in Veterans With Mild Traumatic Brain Injury and Common Co-Occurring Mental Health Conditions: Protocol for a Pilot Ran... by Alyssa Bernanke, Rebecca Hasley, Niki Sabetfakhri, Harriet de Wit, Bridget M Smith, Lei Wang, Lisa A Brenner, Colleen Hanlon, Noah S Philip, Olusola Ajilore, Amy Herrold, Alexandra Aaronson

“…MethodsThis is a pilot, double-blinded, randomized controlled trial. In developing this protocol, we referenced the SPIRIT (Standard Protocol Items: Recommendations for Interventional Trials) guidelines. …”
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Impaired creatinine-based estimated glomerular filtration rate in Thai individuals switching to dolutegravir: illustrating the role of cystatin C testing to aid clinical decision m... by Carlo Sacdalan, Curtis Austin, Aswathy Varma, Suteeraporn Pinyakorn, Eugène Kroon, Donn J. Colby, Phillip Chan, Orlanda Goh, Krittaporn Pornpaisakul, Jintana Intasan, Tassanee Luekasemsuk, Merlin L. Robb, Nitiya Chomchey, Nittaya Phanuphak, Jintanat Ananworanich, Sandhya Vasan, Denise Hsu, the SEARCH 010/RV254 study group

“…During EFV-based ART, an additional 17 (8%) developed eGFRcre < 90 ml/min/1.73 m2, nearly all transient, while mean eGFRcre remained stable and within normal range. …”
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A systematic review of machine learning-based prognostic models for acute pancreatitis: Towards improving methods and reporting quality. by Brian Critelli, Amier Hassan, Ila Lahooti, Lydia Noh, Jun Sung Park, Kathleen Tong, Ali Lahooti, Nathan Matzko, Jan Niklas Adams, Lukas Liss, Justin Quion, David Restrepo, Melica Nikahd, Stacey Culp, Adam Lacy-Hulbert, Cate Speake, James Buxbaum, Jason Bischof, Cemal Yazici, Anna Evans-Phillips, Sophie Terp, Alexandra Weissman, Darwin Conwell, Philip Hart, Mitchell Ramsey, Somashekar Krishna, Samuel Han, Erica Park, Raj Shah, Venkata Akshintala, John A Windsor, Nikhil K Mull, Georgios Papachristou, Leo Anthony Celi, Peter Lee

“…Increasingly machine learning (ML) techniques are being used to develop high-performing prognostic models in AP. However, methodologic and reporting quality has received little attention. …”
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Evaluating associations between patient-to-nurse ratios and mortality, process of care events and vital sign documentation on paediatric wards: a secondary analysis of data from th... by Orsola Gawronski, Corrado Cecchetti, Emanuela Tiozzo, Marta Luisa Ciofi degli Atti, Massimiliano Raponi, Karen Dryden-Palmer, Christopher S Parshuram, George Tomlinson, Immacolata Dall'Oglio, Leah Szadkowski, Ari Robin Joffe

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Low-value clinical practices in adult traumatic brain injury: an umbrella review protocol by Belinda J Gabbe, Henry Thomas Stelfox, Patrick Archambault, François Lauzier, Fiona Lecky, Francois Lamontagne, Michaël Chasse, Pier-Alexandre Tardif, Lynne Moore, Imen Farhat, John Kortbeek, Paule Lessard-Bonaventure, Catherine Truchon, Alexis F Turgeon

“…This work will support the development of metrics to measure the use of low-value practices, inform policy makers on potential targets for deimplementation and in the long term reduce the use of low-value clinical practices in acute TBI care.PROSPERO registration number CRD42019132428.…”
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Four 2×2 factorial trials of smartphone CBT to reduce subthreshold depression and to prevent new depressive episodes among adults in the community–RESiLIENT trial (Resilience Enhan... by Toshi A Furukawa, Pim Cuijpers, Tatsuo Akechi, Masaru Horikoshi, Yan Luo, Hisashi Noma, Takeo Nakayama, Helen Christensen, Naoki Kondo, Norito Kawakami, Aran Tajika, Ronald C Kessler, Shingo Fukuma, Masatsugu Sakata, Rie Toyomoto, James M S Wason

“…In addition, there has been no platform for iCBT that can accommodate ongoing evolution of internet technologies.Methods and analysis Based on our decade-long experiences in developing smartphone CBT apps and examining them in randomised controlled trials, we have developed the Resilience Training App Version 2. …”
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Establishing best practices in cancer online support groups: protocol for a realist review by Geoff Wong, Holly Witteman, Henry Potts, Andrea C Tricco, Olga Perski, Marina Englesakis, Jacqueline L Bender, Charlene Soobiah, Mary Jane Esplen, Richard Wassersug, Stephanie Babinski, Alaina B Cyr, Colleen Young, Victoria Forster, Janet Papadakos, Colleen Fox, Alison Gothard-Huang

“…We will follow Pawson’s five steps and existing quality standards to develop a program theory that explains how cancer online support groups work, for whom and in what circumstances. …”
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Phototherapy for neonatal hyperbilirubinemia and childhood eczema, rhinitis and wheeze by Elizabeth Huiwen Tham, Evelyn Xiu Ling Loo, Anne Goh, Oon Hoe Teoh, Fabian Yap, Kok Hian Tan, Keith M. Godfrey, Hugo Van Bever, Bee Wah Lee, Yap Seng Chong, Lynette Pei-Chi Shek

“…There were also no associations between mean bilirubin peak levels within the phototherapy group with development of eczema, rhinitis and early onset wheeze in the first 5 years of life. …”
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Mental health and sexual and reproductive health services for girls, young women and gender-diverse youth with intersectional identities: protocol for a realist review by Terri Rodak, Sean Kidd, Meaghen Quinlan-Davidson, Jamie Gibson, Amy Gajaria, Jo L Henderson, June Sing Hong Lam, Debbie Chiodo, Jordan Donovan, Mahalia Dixon, Devon Walpole, Karleigh Darnay, Anna I R van der Miesen

“…Findings will be disseminated through peer-reviewed publications, youth-friendly materials and webinars and national and international conferences.PROSPERO registration number CRD42024532422.…”
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Association between long-term use of calcium channel blockers (CCB) and the risk of breast cancer: a retrospective longitudinal observational study protocol by Christopher M Reid, Rachael Moorin, Sallie-Anne Pearson, Max K Bulsara, David B Preen, Gita Mishra, David Youens, Jeffery David Hughes, Ninh Thi Ha, Bruno H Stricker, Rikje Ruiter, Cameron Wright, Chau Ho, Walter P Abhayaratna, Christobel M Saunders, Frank J A van Rooij

“…Results of the proposed study will be published in high-impact journals and presented at key scientific meetings.Trial registration number NCT05972785.…”
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