Leveraging machine learning for duration of surgery prediction in knee and hip arthroplasty – a development and validation study by Benedikt Langenberger, Daniel Schrednitzki, Andreas Halder, Reinhard Busse, Christoph Pross

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Development of an Approach to Integrated Epidemiological Zoning of West Nile Fever Endemic Territory (by the Example of the Volgograd Region) by D. N. Nikitin, S. K. Udovichenko, K V Zhukov, E. V. Putintseva, D. V. Viktorov, A. V. Toporkov

“…Aims. To develop a methodology for differentiating the territory according to the degree of potential epidemic hazard of West Nile virus (WNV) infection and to test it by the example of the Volgograd region. …”
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Protocol to develop a core outcome set in incisional hernia surgery: the HarMoNY Project by Ben Griffiths, Neil Smart, Lisa Massey, Manuel López-Cano, Marc Miserez, Deena Harji, Agneta Montgomery, Christophe Thomas, Stavros Antoniou, Harsha Chandraratan, B Todd Heniford, Liam Horgan, Ferdinand Koeckerling, Filip Muysoms, Benjamin Poulose, Wolfgang Reinpold

“…This study has been registered with the Core Outcome Measures in Effectiveness Trials initiative.PROSPERO registration number CRD42018090084.…”
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Wearable sensors for measuring spontaneous upper limb use in children with unilateral cerebral palsy and typical development by Elena Beani, Mattia Franchi de ’Cavalieri, Silvia Filogna, Veronica Barzacchi, Matteo Cianchetti, Martina Maselli, Giada Martini, Valentina Menici, Giuseppe Prencipe, Elisa Sicola, Giovanni Cioni, Giuseppina Sgandurra

“…Trial registration Clinical Trials.gov (NCT03054441).…”
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Development of a predictive model for systemic lupus erythematosus incidence risk based on environmental exposure factors by Qianjin Lu, Ying Zhang, Cheng Zhao, Yu Lei, Hui Jin, Qilin Li

“…Leave-one-out cross-validation confirmed that the ForestMDG model had the best accuracy (0.8338). Finally, we developed a dynamic nomogram for practical use, which is accessible via the following link: https://yingzhang99321.shinyapps.io/dynnomapp/.Conclusion We created a user-friendly dynamic nomogram for predicting the relative risk of SLE onset based on occupational and living environmental exposures.Trial registration number ChiCTR2000038187.…”
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CRISPR/Cas9-Mediated Development of Potato Varieties with Long-Term Cold Storage and Bruising Resistance by Gabriela Alejandra Massa, Cecilia Andrea Décima Oneto, Matías Nicolás González, Anabela Poulsen Hornum, Ailín Arizmendi, Sofía Sucar, Silvina Beatriz Divito, Sergio Enrique Feingold

“…Using CRISPR/Cas9, we developed gene-edited potato lines with improved resistance to browning and CIS. …”
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Developing an AI-powered wound assessment tool: a methodological approach to data collection and model optimization by Alessio Stefanelli, Sofia Zahia, Guillaume Chanel, Rania Niri, Swann Pichon, Sebastian Probst

“…The AI-based wound segmentation model, developed using the Deeplabv3 + architecture with a ResNet50 backbone, achieved a DICE score of 92% and an Intersection-over-Union (IOU) score of 85%. …”
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Development of a statewide network hub for screening, referral, and enrollment into food as medicine programs across Kentucky by Christa Mayfield, Carolyn Lauckner, Joshua Bush, Ethan Cosson, Lauren Batey, Alison Gustafson, Alison Gustafson

“…The University of Kentucky Food as Health Alliance first piloted the development of a statewide hub facilitating referral to, enrollment in, and evaluation of food as medicine programs across two healthcare providers (one urban and one rural). …”
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Characterization of medical device constituents and development of duration-based non-cancer threshold of toxicological concern values by Taylor Builee, Todd A. Kennedy, Valériane Levelut, Megan A. Hahn, Stephen Bond, Michael K. Peterson, Frances K. Hsia, Alessia Stornetta, Kristin J. Erickson, Kimberly D. Ehman, Bindu Prabhakar, Bradford D. Bagley, Sherry P. Parker

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Design and development of the Pediatric Urology Recovery After Surgery Endeavor (PURSUE) multicentre pilot and exploratory study by Kyle O Rove, Andrew C Strine, Duncan T Wilcox, Gino J Vricella, Timothy P Welch, Brian VanderBrink, David I Chu, Rajeev Chaudhry, Rebecca S Zee, Megan A Brockel, Douglas E. Coplen, Paul F. Austin, Erica J. Traxel, Jacob AuBuchon, Robert P. Moore, Vijaya M. Vemulakonda, Brian T. Caldwell, Carter J. Sevick, Nicholas Burjek, Elizabeth B. Yerkes, Yvonne Y. Chan, C.D. Anthony Herndon

“…We anticipate this study will take 4 years to fully accrue with completed follow-up.Trial registration number NCT03245242; Pre-results.…”
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Identification of luteolin-7-glucoside metabolites after oral administration and development of a method for their quantitative analysis by G. V. Adamov, O. L. Saybel, A. N. Babenko, E. S. Melnikov, A. I. Radimich, O. Yu. Kulyak, L. V. Krepkova

“…Introduction. The development and registration of antiviral drugs is an urgent task. …”
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Addressing the Socioemotional Dimension of Medical Education: Protocol for a Scoping Review of Student-Driven Development Strategies by Cintia Canato Martins, Marco Antônio Ribeiro Filho, Christian Guilherme Capobianco dos Santos, Luana Ribeiro Altrão lorino, João Daniel de Souza Menezes, Matheus Querino da Silva, Loiane Letícia dos Santos, Emerson Roberto dos Santos, Natalia Almeida de Arnaldo Silva Rodriguez Castro, Helena Landin Gonçalves Cristóvão, Randolfo dos Santos Júnior, Gerardo Maria de Araújo Filho, Patrícia da Silva Fucuta, Alba Regina de Abreu Lima, Vânia Maria Sabadoto Brienze, Denise Cristina Móz Vaz Oliani, Neide Aparecida Micelli Domingos, Maria Cristina de Oliveira Santos Miyazaki, Júlio César André

“…Protocol development and registration was completed in January 2025. …”
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THE ROLE OF THE RIAU PROVINCIAL GOVERNMENT IN ENHANCING REGIONAL ECONOMIC DEVELOPMENT THROUGH POTENTIAL GEOGRAPHICAL INDICATION PRODUCTS by Ledy Diana, Adi Tiaraputri, Evi Deliana HZ, Ricki Musliadi

“…Using empirical legal research, this research finds that the Riau Provincial Government can strengthen the regional economy by mapping GI potential, facilitating registrations, developing protected products, and promoting legal protection and recognition at national and international levels. …”
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Congress "Chemical-Pharmaceutical and Biological Drugs: pharmaceutical and clinical development in accordance with the rules of the EAEU" took place in Moscow by article Editorial

“…The conference is traditionally organized by the Center for Pharmaceutical Analytics LLC and the journal Drug development & registration. The event was attended by 149 visitors.…”
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Develop Bactra system to determine Mutagens in the Environment, Food III: use emulators nitrogenous bases 5 - Bromeuruasil by Baghdad Science Journal

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Developing an integrated cadastre model of land and real estate in a single setting in Ukraine: key aspects and problems by Nazar Stupen, Mariia Melnyk

“…The authors outline the major directions and prospects for the development of such a model. The introduction of a hybrid 3D cadastre model, as an intermediate stage in the transition to a fully developed 3D cadastre, is expected to facilitate the integration of Ukraine’s existing State Land Cadastre and registration system into European and global cadastral systems. …”
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Development and Validation of a Method for the Quantification of an Alkaloid Fraction of Himatanthus lancifolius (Muell. Arg.) Woodson by Ultraviolet Spectroscopy by Patrícia M. S. S. Barros, Nádia M. G. de Couto, Andressa S. B. Silva, Wagner L. R. Barbosa

“…For the registration of phytomedicines and their availability to the population, National Agency of Sanitary Surveillance (ANVISA) establishes quality, security, and efficacy parameters, stipulating control requirements similar to those applied to synthetic medicines. …”
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Development and content validation of the Childhood Early Oral Aging Syndrome (CEOAS) index for the deciduous dentition: Research protocol. by Amanda Rafaelly Honório Mandetta, Thais Gimenez, Ana Paula Taboada Sobral, Sandra Gouveia Spinola, Marcela Leticia Leal Gonçalves, Paulo Vinícius Soares, Elaine Marcilio Santos, José Carlos Pettorossi Imparato, Anna Carolina Ratto Tempestini Horliana, Raquel Agnelli Mesquita-Ferrari, Lara Jansiski Motta, Kristianne Porta Santos Fernandes, Sandra Kalil Bussadori

“…Trial registration: ClinicalTrials.gov ID: NCT06378385.…”
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Development of a Thermal Infrared Network for Volcanic and Environmental Monitoring: Hardware Design and Data Analysis Software Code by Fabio Sansivero, Giuseppe Vilardo, Ciro Buonocunto

“…The processing of TIR imagery is carried out using ASIRA (Automated System of InfraRed Analysis), a free software package, now developed for GNU Octave. ASIRA performs quality filtering and co-registration, and applies various seasonal correction methodologies to extract time series of deseasoned surface temperatures, estimate heat fluxes, and track variations in thermally anomalous areas. …”
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The drospirenone only pill as a contraceptive option for breastfeeding women: First data on users’ acceptability and newborn development by Pedro Antonio Regidor, Enrico Colli, Artur Jakimiuk

“…The study aimed to analyze for those successful users the impact on new-born development, the bleeding profile and evaluate user satisfaction.Results Analysis of the newborns showed that their growth parameters length and weight, were within the expected range of standard development. …”
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