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  1. 4181

    Effectiveness of virtual reality technology in rehabilitation after anterior cruciate ligament reconstruction: A systematic review and meta-analysis. by Yunchuan Li, Junjie Peng, Jintao Cao, Yang Ou, Jiaming Wu, Weisha Ma, Feng'e Qian, Xiaoqian Li

    Published 2025-01-01
    “…<h4>Background</h4>Anterior cruciate ligament reconstruction (ACLR) can be fully recovered with effective rehabilitation, which also lowers the risk of developing osteoarthritis in the knee. Virtual reality technology (VRT) has been used for rehabilitation after ACLR. …”
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  2. 4182

    Trusted health system implementation strategies to increase vaccination (TRUE SYNERGI): a stepped-wedge cluster randomized trial to reduce HPV-related cancers by Daisy Y. Morales-Campos, Prajakta Adsul, Yuanyuan Liang, Erin Donovan, Leticia R. Moczygemba, Jessica A. Kahn

    Published 2025-04-01
    “…We will conduct baseline assessments at each practice, which will provide data to assist the practice facilitator in engaging with the providers and leadership to develop a tailored implementation plan for each practice. …”
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  3. 4183
  4. 4184

    Cognitive Behavioral Immersion for Depression: Protocol for a Three-Arm Randomized Controlled Trial of Peer-Based Coaching in the Metaverse by Noah Robinson, Francisco N Ramos, Steven D Hollon, Gloria T Han, Iony D Ezawa

    Published 2025-05-01
    “…Cognitive behavioral immersion (CBI)—a cognitive behavioral skills training intervention delivered by peer coaches in the metaverse—has been developed to address these barriers. CBI can be used through a virtual reality headset or via flat-screen devices such as phones, tablets, or computers. …”
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  5. 4185
  6. 4186

    Six-month intervention effect of a digital movement behavior intervention on parent- and child intermediary outcomes—results from the Let’s Grow randomized controlled trial by Johanna Sandborg, Katherine L. Downing, Liliana Orellana, Rachael W. Taylor, Lisa M. Barnett, Valerie Carson, Kylie D. Hesketh

    Published 2025-06-01
    “…Engagement appears to enhance intervention effects, highlighting the importance of strategies to optimize engagement. Trial registration ACTRN12620001280998; U1111-1252–0599.…”
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  7. 4187

    Assessing Sedation Depth with PSI in Elderly ERCP Patients: A Prospective Cohort Study by Huang L, Liu LL, Lu YD, Zhuang MY, Dou W, Liu H, Ji FH, Peng K

    Published 2025-02-01
    “…Five patients (8.8%) experienced PSI < 25 for at least 10 min, and three of them (5.3%) showed EEG burst suppression. No patients developed desaturation or intra-procedural awareness. …”
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  8. 4188

    Efficacy and safety of NeoAdjuvant chemotherapy with or without tIslelizumab followed by debulking surgery for oVarian cancEr (NAIVE study) in China: study protocol of an open-labe... by Ying Zhu, Jianwei Zhou, Zhigang Zhang, Jiaojiao Zhang, Jing Fei, Xiaoqing Zhu

    Published 2025-02-01
    “…Presentations at scientific and professional meetings and publication in peer-reviewed journals will disseminate the results of the study.Trial registration number NCT04815408.…”
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  9. 4189
  10. 4190

    Gaming-Based Tele-Exercise Program to Improve Physical Function in Frail Older Adults: Feasibility Randomized Controlled Trial by Lakshmi Kannan, Upasana Sahu, Savitha Subramaniam, Neha Mehta, Tanjeev Kaur, Susan Hughes, Tanvi Bhatt

    Published 2024-11-01
    “…This contributes to accelerated aging processes, leading to adverse health outcomes and reduced quality of life. We have developed and piloted the design, usability, safety, and feasibility of a gaming-based cognitive-motor (CogXergaming) tele-exercise protocol in prefrail older adults. …”
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  11. 4191

    Social Cognitive Treatment (T-ScEmo) for Various Neurological Patient Groups: Study Rationale and Protocol for a Randomized Control Trial (T-ScEmo4ALL) by A. Heegers, S. E. Rakers, S. van Twillert, V. R. M. Moulaert, M. M. J. Gerritsen, J. van der Naalt, J. M. Spikman, H. J. Westerhof-Evers

    Published 2025-03-01
    “…Recently, the first multi-faceted treatment, T-ScEmo (Treatment for Social Cognition and Emotion Regulation) has been developed and evaluated for patients with TBI. T-ScEmo showed to be effective in improving social cognitive functioning, participation, relationships, and quality of life. …”
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  12. 4192

    Lipid-Lowering Efficiency and Safety of Alirocumab 300 mg Using a 2-mL Autoinjector Device in Real-World Practice: The MARS Study by Klaus G. Parhofer, Peter Bramlage, Constanze Gries, Cornelia Harder, Christiane Look, W. Dieter Paar, Ursula Rauch-Kröhnert

    Published 2025-01-01
    “…Recently, a 2-mL prefilled autoinjector has been developed to support the monthly 300-mg dosing regimen with a single-injection administration. …”
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  13. 4193
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  15. 4195

    Use of Technology to Support Health Care Providers Delivering Care in Low- and Lower-Middle-Income Countries: Systematic Umbrella Review by Adam Craig, Harriet Lawford, Maggie Miller, Liuyi Chen-Cao, Leanna Woods, Siaw-Teng Liaw, Myron Anthony Godinho

    Published 2025-06-01
    “…DHIs should be seen not as a stand-alone solution but as a complementary tool to strengthen health systems. Trial RegistrationPROSPERO CRD42024586285; www.crd.york.ac.uk/PROSPERO/view/CRD42024586285…”
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  16. 4196

    Effectiveness of transitional care interventions in patients with serious illness and their caregivers: a systematic review and metanalysis of randomized controlled trial by Marco Di Nitto, Angela Durante, Gabriele Caggianelli, Jacopo Fiorini, Silvia Sferrazza, Kusumam Pampoorickel, Roberto Accettone, Dhurata Ivziku, Daniela D’Angelo

    Published 2025-05-01
    “…Evidence certainty was evaluated using the Grading of Recommendations Assessment, Development, and Evaluation (GRADE) approach. Results We included 16 studies with 3781 participants. …”
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  17. 4197

    Global epidemiological characteristics of malnutrition in cancer patients: a comprehensive meta-analysis and systematic review by Jinhui Zhang, Yumeng Quan, Xiaolin Wang, Xiaolei Wei, Xueli Shen, Xue Li, Tao Liang

    Published 2025-07-01
    “…The Global Leadership Initiative on Malnutrition (GLIM) criteria, published in 2019, were established to compare the prevalence of malnutrition globally, drive the development of standardized care practices, and promote improved clinical outcomes. …”
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  18. 4198

    An Automated Conversational Agent Self-Help Program: Randomized Controlled Trial by Heather M Foran, Christian Kubb, Janina Mueller, Spencer Poff, Megan Ung, Margaret Li, Eric Michael Smith, Akinniyi Akinyemi, Melanie Kambadur, Franziska Waller, Mario Graf, Y-Lan Boureau

    Published 2024-12-01
    “…ObjectiveThis study aims to develop and test the effectiveness and implementation of a new, widely targeted conversational agent prevention program (Zenny) designed to enhance well-being. …”
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  19. 4199

    sCD40 and sCD40L as candidate biomarkers of rheumatic diseases: a systematic review and meta-analysis with meta-regression by Angelo Zinellu, Arduino A. Mangoni, Arduino A. Mangoni

    Published 2025-03-01
    “…Large, appropriately designed prospective studies in a wide range of RDs are warranted to investigate whether measuring sCD40 and sCD40L can significantly improve the performance of currently available diagnostic criteria and serological biomarkers. (PROSPERO registration number: CRD42024577430).Systematic review registrationhttps://www.crd.york.ac.uk/PROSPERO/view/CRD42024577430, identifier PROSPERO CRD42024577430.…”
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  20. 4200

    Testing the Recruitment Frequency, Implementation Fidelity, and Feasibility of Outcomes of the Heart Failure Activity Coach Study (HEALTHY): Pilot Randomized Controlled Trial by Andreas Blomqvist, Maria Bäck, Leonie Klompstra, Anna Strömberg, Tiny Jaarsma

    Published 2025-01-01
    “…Adherence to the Activity Coach app was high, and it may be able to support older adults with HF in being physically active. Trial RegistrationClinicalTrials.gov NCT05235763; https://clinicaltrials.gov/study/NCT05235763…”
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