Olympic combat sports and mental health in children and adolescents with disability: a systematic review of controlled trials by Youngjun Lee, Flavia Guidotti, Flavia Guidotti, Laura Capranica, Caterina Pesce, Valentin Benzing, Janet Hauck, Simone Ciaccioni, Simone Ciaccioni

“…However, not much is known about their mental health impact on this population.MethodsFollowing PRISMA-P protocols (PROSPERO registration: CRD42023452489), we searched seven databases for randomized controlled trials or non-randomized trials that evaluated the impact of OCS on mental health in children and adolescents (5–18 years) with developmental or physical disabilities. …”
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Randomised controlled trial of gradual antipsychotic reduction and discontinuation in people with schizophrenia and related disorders: the RADAR trial (Research into Antipsychotic... by Rachael Hunter, Louise Marston, Nick Freemantle, Sonia Johnson, Joanna Moncrieff, Vanessa Pinfold, Stefan Priebe, Robert Horne, Thomas R E Barnes, Glyn Lewis, Nicola Morant, Lyn J Kent, Ruth Smith, Katherine Darton, Nadia E Crellin, Ruth E Cooper

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Effects of different physical exercise programs on blood pressure in overweight children and adolescents: systematic review and meta-analysis by João Victor Affornali Tozo, Maiara Cristina Tadiotto, Tatiana A Affornali Tozo, Francisco Jose de Menezes-Junior, Jorge Mota, Beatriz Oliveira de Pereira, Rafaela Rosário, Neiva Leite

“…Systematic review registration number PROSPERO no CRD42023469222.…”
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Continuing medical education in Serbia with particular reference to the Faculty of Medicine, Belgrade by Bjegović-Mikanović Vesna, Lalić Nebojša, Wenzel Helmut, Nikolić-Mandić Ružica, Laaser Ulrich

“…Continuing Medical Education (CME), conceptualised as lifelong learning (LLL) aims at improving human resources and continuing professional development. Various documents of European institutions underline its key importance. …”
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Safety and therapeutic potential of allogeneic adipose-derived stem cell spray transplantation in ischemic cardiomyopathy: a phase I clinical trial by Takuji Kawamura, Daisuke Yoshioka, Ai Kawamura, Yusuke Misumi, Takura Taguchi, Daisuke Mori, Shunsuke Saito, Takashi Yamauchi, Hiroki Hata, Shigeru Miyagawa

“…One patient in the ADSC group developed pleural effusion that was resolved with drainage. …”
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Counselling for physical activity, life-space mobility and falls prevention in old age (COSMOS): protocol of a randomised controlled trial by Pekka Kannus, Ari Heinonen, Harri Sievänen, Lasse Kannas, Timo Rantalainen, Johanna Edgren, Saija Karinkanta, Taina Rantanen, Robin Daly, Timo Törmäkangas, Sarianna Sipilä, Outi Teittinen, R Nikander

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Evaluation Methods, Indicators, and Outcomes in Learning Health Systems: Protocol for a Jurisdictional Scan by Shelley Vanderhout, Marissa Bird, Antonia Giannarakos, Balpreet Panesar, Carly Whitmore

“…ConclusionsThis research will characterize the current landscape of LHS evaluation approaches and provide a foundation for developing consistent and scalable metrics of LHS growth, maturity, and success. …”
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Does the degree of limitation in activities of daily living in geriatric patients influence the amount of care and case management required? An analysis from the RubiN project by Simone Gloystein, Heiko Krause, Sonja Laag, Neeltje van den Berg

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Single Herbal Medicine for Insulin Resistance: Protocol for a Systematic Review and Meta-Analysis of Randomized Clinical Trials by Jialing Zhang, Zhinan Zhang, Hoi Ki Wong, Shuyan Zhong, Zhilin Lin, Zhaoxiang Bian

“…The overall certainty of evidence will be assessed using Grading of Recommendations Assessment, Development, and Evaluation (GRADE). The primary outcome will include measurements that assess IR, such as the hyperinsulinemic-euglycemic clamp, homeostatic model assessment, insulin sensitivity index, and oral glucose tolerance test. …”
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Effect of dry needling plus static stretching on plantar flexor spasticity, function, and quality of life in a patient with chronic stroke: a case report by Mahdi Esmaeeli, Nastaran Ghotbi, Kazem Malmir, Noureddin Nakhostin Ansari, Pablo Herrero, Shohreh Jalaie, Elham Loni, Sajede Mazidi

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The Machine Learning Models in Major Cardiovascular Adverse Events Prediction Based on Coronary Computed Tomography Angiography: Systematic Review by Yuchen Ma, Mohan Li, Huiqun Wu

“…Specifically, LR-based ML diagnostic models demonstrated significant clinical potential, particularly when combined with clinical features, and are worth further validation through more clinical trials. Trial RegistrationPROSPERO CRD42024596364; https://www.crd.york.ac.uk/PROSPERO/view/CRD42024596364…”
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Assessment of the differences in Mean Age at Menarche (MAM) among adolescent girls in rural and urban Nigeria: a systematic review by Hilary I. Okagbue, Olugbemisola W. Samuel, Emmanuella C. Nzeribe, Sunday E. Nto, Olukayode E. Dahunsi, Muhammad B. Isa, John Etim, Evelyn E. Orya, Sidney Sampson, Alexey V. Yumashev

“…PROSPERO Registration CRD42024529497…”
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Evaluating the effects of a resistance exercise intervention for sarcopenia in patients receiving neoadjuvant chemotherapy for breast cancer: study protocol for a randomized contro... by Min Kyeong Jang, Seho Park, Justine Y. Jeon, Min Jae Kang, Chang Park, Ardith Z. Doorenbos, Sue Kim

“…Trial registration This trial was prospectively registered in the Clinical Research Information Service (reference number KCT0008961) in the Republic of Korea on November 16, 2023.…”
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Population pharmacokinetics and pharmacodynamics of two dosing regimens of antenatal corticosteroids: protocol for a prospective nested study in a randomised controlled trial by Adejumoke Idowu Ayede, Olufemi T Oladapo, Rekha Bharti, Nitya Wadhwa, Tina Lavin, Nicole Minckas, Ebunoluwa A Adejuyigbe, Shivaprasad S Goudar, William Jusko, Shuchita Gupta, Ayesha De Costa, Adesina Olubukola Adeponle, Ramana Moorthy Aripaka, Francis Olubanji Awoniyi, Nurudeen Ola Bello, Anjali Dabral, Zubair Hasan, Dennis Anthony Isah, Ranjit P Kangle, Wojciech Krzyzanski, Olatunji Okikiola Lawal, Elijah-David Ukpahiu-Ojo Ogwu, Kabir Olatunde Oyeniyi, Amaresh P Patil, Yeshita V Pujar, Subramanian Ramachandran, Sunil Ranga, Ezekiel Onoja Ray, Suresh Sivasankaran, Manjunath S Somannavar, Jyotsna Suri

“…The study results will be published in a peer-reviewed journal and presented at scientific conferences.Trial registration number ISRCTN11434567.…”
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Mobile Health–Based Motivational Interviewing to Promote SARS-CoV-2 Vaccination in Rural Adults: Protocol for a Pilot Randomized Controlled Trial by Ashlea Braun, Sarah Corcoran, Khue Tu Doan, Cameron Jernigan, Cate Moriasi, Michael Businelle, Thanh Bui

“…ObjectiveThis study aims to develop and evaluate the feasibility, acceptability, and preliminary efficacy of our mHealth-based MI intervention to diminish SARS-CoV-2 vaccine hesitancy (MOTIVACC). …”
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Patients’ Experiences of Digital Health Interventions for the Self-Management of Chronic Pain: Systematic Review and Thematic Synthesis by Ashleigh Main, Haruno McCartney, Maryam Ibrar, Fiona Muirhead, Alexandra Mavroeidi, Harleen Kaur Rai, Roma Maguire

“…Trial RegistrationPROSPERO CRD42023445100; https://www.crd.york.ac.uk/PROSPERO/view/CRD42023445100 International Registered Report Identifier (IRRID)RR2-10.2196/52469…”
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Are there differences in efficacy and safety between local and imported direct-acting antiviral agents for hepatitis C in China? by Zhitao Wang, Youbing Ran, Yihan Fu, Jing Sun, Yuanli Liu

“…It is critical for local DAA developers to generate more evidence with expanded patient population in terms of age, treatment experience and genotype of hepatitis C virus, conducting head-to-head studies directly comparing the efficacy and safety. …”
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Implementation and Effects of an Online Intervention Designed to Promote Sleep During Early Infancy: A Randomized Trial by Anzman-Frasca S, Goldsmith J, Hassinger AB, Savage JS, Gupta V

“…Parent perspectives support acceptability of the approach and highlight the potential for further development of this scalable online intervention and examination of its impacts on additional aspects of well-being.Clinical Trial Registration: The study was registered prior to participant enrollment at clinicaltrials.gov (NCT05322174). …”
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PHOENIX (Picking up Hidden Osteoporosis Effectively during Normal CT Imaging without additional X-rays): protocol for a randomised, multicentre feasibility study by Lee Shepstone, Jane Fleming, Stephen K Kaptoge, Emma Clark, Adam P Wagner, Kenneth E S Poole, Daniel D G Chappell, Thomas D Turmezei, Karen Willoughby

“…Dissemination will be through the Royal Osteoporosis Society (to patients and public) as well as to clinician peers via national and international bone/rheumatology scientific and clinical meetings.Trial registration number ISRCTN14722819.…”
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Investigation into repetitive concussion in sport (RECOS): study protocol of a prospective, exploratory, observational cohort study by Kamal M Yakoub, David J Davies, Conor Bentley, Callum N Watson, Mario Forcione, Emma Toman, Douglas Hammond, Antonio Belli, Vijay Sawlani, Zhangjie Su, Jon Bishop, Lauren Cooper, Aron K Barbey, Michael J Grey

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