Relationship between endotoxin core and staphylococcal antibody levels and outcome following transcatheter aortic valve implantation (TAVI) by Andrew Smith, James Fullerton, John Whittle, James Moon, Michael Mullen, Paul Scully, Colin Hamilton-Davies

“…Primary outcome measure was post-procedure length of stay (LOS) in hospital with secondary outcome being development of infective complications. Correlations were examined using Spearman rank order or Kendall Tau-b methods. …”
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Phase 1 Trials of Gatralimab, a Next-Generation Humanized Anti-CD52 Monoclonal Antibody, in Participants with Progressive Multiple Sclerosis by Fredrik N. Albach, Christian Geier, Christian Keicher, Maximilian G. Posch, Stephan J. Schreiber, Gerald Grütz, Levent Akyüz, Xiaodong Luo, Annaig Le-Halpere, Philippe Truffinet, Frank Wagner

“…Trial registration NCT02282826, NCT02977533, NCT02313285.…”
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Parallels of structural-functional parameters the myocardium, C-type natriuretic peptide and endothelin-1 plasma concentrations in women with uncomplicated essential hypertension by V. V. Petrovska, B. M. Zhebel

“…The development of endothelial dysfunction (DE)plays an important role in the pathogenesis of essential hypertension (EH). …”
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SLEEP DISORDERS AND THE RISK OF MYOCARDIAL INFARCTION AND STROKE IN MEN OF NOVOSIBIRSK CITY by V. V. Gafarov, E. A. Gromova, I. V. Gagulin, A. V. Gafarova, D. O. Panov

“…The program of screeing examination included the registration of social and demographic data, sleep disorders assessment with Jenkins C. …”
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Nurse-led weaning protocols—a systematic review and meta-analysis by Yingying Wang, Yingying Wang, Yan Wang, Su Gu, Liqun Zhu, Ruixiao Jia, Min Tan, Shaoyong Ma

“…The certainty of evidence was assessed using the Grades of Recommendation, Assessment, Development, and Evaluation (GRADE) profiler Guideline Development Tool.ResultsOur analysis included a total of six relevant studies. …”
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A phase 3 randomised study of enzalutamide plus leuprolide and enzalutamide monotherapy in high-risk non-metastatic hormone-sensitive prostate cancer with rising PSA after local th... by Ugo De Giorgi, Martin Gleave, Brad Rosbrook, Stephen J Freedland, Qi Shen, Jennifer Sugg, Gabriel P Haas, Neal D Shore

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Neurocognitive and emotional long-term effects of COVID-19 infections in children and adolescents: results from a clinical survey in Bavaria, Germany by Julia Hauke-Gleißner, Irina Jarvers, Silke Jordan, Stephan Gerling, Michael Kabesch, Romuald Brunner, Stephanie Kandsperger

“…Patients with allergies exhibited a higher risk of developing a post-COVID adjustment disorder. For the post-COVID attention deficit disorder, age, sex, obesity, pre-existing psychiatric diagnosis, and the virus variant were relevant factors. …”
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A Personalized, Texting-Based Conversational Agent to Address Sleep Disturbance in Individuals Who Have Survived Breast Cancer: Protocol for a Pilot Waitlist Randomized Controlled... by Chi-shan Tsai, Warren Szewczyk, Michelle Drerup, Jason Liao, Alexi Vasbinder, Heather Greenlee, Jaimee L Heffner, Rachel Yung, Kerryn W Reding

“…Despite the potential for wider dissemination of CBTi via digital means, these modalities have unique challenges, including technology barriers and poor adherence. We developed a conversational agent (CA) to deliver CBTi via a SMS text messaging intervention, supported by mobile-ready web content. …”
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The feasibility of conducting a randomized controlled trial that compares immediate versus optional delayed surgical repair for treatment of acute Anterior cruciate ligament injury... by Feryal Ghafelzadeh Ahwaz, Annemie Smeets, Stijn Bogaerts, Pieter Berger, Koen Peers

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Efficacy of virtual reality assisted guided imagery (VRAGI) in a home setting for pain management in patients with advanced cancer: protocol for a randomised controlled trial by Andrew Todd, Rosalba Hernandez, George Hartshorn, Matthew Browning, Kapil Chalil Madathil, Fredric Mau, Shyam Ranganathan, Jeff Bertrand, Allison Maynard, Olivia McAnirlin, Kailan Sindelar, Teny Henry Gomez

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New opportunities for preclinical diagnostics of antitumor therapy cardiotoxicity: results of an observational study by Yu. A. Vasyuk, D. A. Vyzhigin, E. Y. Shupenina, E. O. Novosel, E. A. Ulyanova

“…During the observation of oncological patients receiving chemo- and targeted therapy, it was found that a specific pattern, previously not described, was revealed in patients with developed systolic dysfunction upon visual assessment of the longitudinal strain of the LV. …”
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Study protocol: A national cross‐sectional study on psychology and behavior investigation of Chinese residents in 2023 by Diyue Liu, Siyuan Fan, Xincheng Huang, Wenjing Gu, Yifan Yin, Ziyi Zhang, Baotong Ma, Ruitong Xia, Yuanwei Lu, Jingwen Liu, Hanjia Xin, Yumeng Cao, Saier Yang, Runqing Li, Han Li, Ji Zhao, Jin Zhang, Zheng Gao, Yaxin Zeng, Yixiao Ding, Zhuolun Ren, Yan Guan, Na Zhang, Jia Li, Yan Ma, Pei Wei, Jingjing Dong, Yajing Zhou, Yong Dong, Yan Qian, Chen Chen, Yujie Zhao, Yimiao Li, Yujia Zheng, Rongyi Chen, Xiaomeng Li, Yuke Han, Yaoyao Xia, Huixin Xu, Zhaolin Wu, Mingyou Wu, Xinrui Wu, Junyi Hou, Yuelai Cai, Xiaofan Dai, Wenbo Li, Ting Nie, Chongzhe Zhang, Xiaoya Wang, Dan Li, Siyao Yan, Zhiheng Yi, Chenxi Liu, Xinyue Zhang, Lei Shi, Haomiao Li, Feng Jiang, Xiaoming Zhou, Xinying Sun, Yibo Wu, Psychology and Behavior Investigation of Chinese Residents project team

“…Discussion Data collection has been finished, and scientific outputs based on this data will support the development of health promotion strategies in China and globally. …”
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Efficacy and safety of early treatment with sarilumab in hospitalised adults with COVID-19 presenting cytokine release syndrome (SARICOR STUDY): protocol of a phase II, open-label,... by Jesús Rodríguez-Baño, Antonio Luque-Pineda, Julian Torre-Cisneros, M Ángeles Esteban-Moreno, Rafael León López, Sheila Cárcel Fernández, Laura Limia Pérez, Alberto Romero Palacios, María Concepción Fernández-Roldán, Eduardo Aguilar Alonso, Inés Pérez Camacho, Nicolás Merchante, Julián Olalla, Marta Santos

“…Introduction About 25% of patients with COVID-19 develop acute respiratory distress syndrome (ARDS) associated with a high release of pro-inflammatory cytokines such as interleukin-6 (IL-6). …”
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Protocol of the follow-up of patients with transthyretin amyloid cardiomyopathy by multimodality imaging (FAITH) study: a prospective observational study in patients with ATTR-CM u... by Bettina Heidecker, Jeanette Schulz-Menger, Ingolf Sack, Carsten Schwenke, Jan Gröschel, Gina Barzen, Jasmin Zernikow, Edyta Blaszczyk, Katrin Hahn, Helena F Pernice, Elena Romero Dorta, Phillip van Dijck, Sebastian Spethmann

“…The final statistical analysis will be based on developing a multiparametric score for the prediction of treatment response. …”
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Effectiveness and safety of acupuncture therapy for inflammatory bowel disease: a protocol of systematic review and meta-analysis by Fan-rong Liang, Ning Sun, Rui-Rui Sun, Yuan-Fang Zhou, Shi-Rui Cheng, Xiao-Dong Deng, Xiang-Yin Ye, Zheng-Jie Li, Gui-Xing Xu, Yu-Zhu Qu, Liu-Yang Huang

“…The results will be published and diffused in a peer-reviewed journal or relative conferences.Trial registration number CRD42020157903.…”
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Neuroeducational Environment for Acquisition of Competencies in the Field of End-To-End Digital Technologies (Neurotechnology) in the Conditions of Digital Transformation by M. E. Mazurov, A. A. Mikryukov, V. A. Titov, I. G. Fedorov

“…A software tool for teaching standard and selective neurotechnologies was developed and proposed, for which a certificate of state registration of a computer program was obtained. …”
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Effect of spironolactone on cardiovascular morbidity and mortality in patients with hypertension and glucose metabolism disorders (ESCAM): a study protocol for a pragmatic randomis... by Nanfang Li, Lin Wang, Qin Luo, Jing Hong, Yuanyuan Li, Mengyue Lin, Mulalibieke Heizhati, Jina Yili, Xiaoguang Yao, Qing Zhu

“…Introduction Hypertension combined with diabetes and hypokalemia is more likely to develop hyperaldosteronism and is at higher risk of cardiovascular events. …”
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MultiAgency, prospective, exploratory, non-intervention, cohort Study on Human Impact Exposure oNboard high-speed boats (MASHIEN): protocol by Stephen D Myers, Ola Rolfson, Yohan Robinson, Spyros D Masouros, John J Fraser, Yann Daniel, Johan Ullman, Kai-Thorsten Bretschneider, Karen R Kelly, Victor Hurpin, Justus Kaehler, Jan Ivar Kåsin, Knut Hveding, Neil Mansfield, Daniel Perl, Nicole Wijnands, Isabelle Vallee, Veerle Stevens

“…The findings will be disseminated through technical reports, articles in peer-reviewed journals, conference presentations and direct engagement with military and maritime stakeholders to enhance training protocols and safety measures.Trial registration number NCT05299736.…”
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Design of a Cost-Effective Ultrasound Force Sensor and Force Control System for Robotic Extra-Body Ultrasound Imaging by Yixuan Zheng, Hongyuan Ning, Eason Rangarajan, Aban Merali, Adam Geale, Lukas Lindenroth, Zhouyang Xu, Weizhao Wang, Philipp Kruse, Steven Morris, Liang Ye, Xinyi Fu, Kawal Rhode, Richard James Housden

“…To address these challenges, we developed a cost-effective, lightweight, 3D-printed force sensor and a hybrid position–force control strategy tailored for robotic ultrasound scanning. …”
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RadBone: bone toxicity following pelvic radiotherapy – a prospective randomised controlled feasibility study evaluating a musculoskeletal health package in women with gynaecologica... by Janelle Yorke, Sarah O’Connell, Sally Taylor, Karen Johnson, Robert G Bristow, Martin Eden, Kate Haslett, John Moore, Rohit Kochhar, Victoria Chatzimavridou Grigoriadou, Lisa H Barraclough, Ivona Baricevic-Jones, Zoe Merchant, Thomas Westwood, Anthony David Whetton, Claire E Higham

“…Introduction Patients receiving radiotherapy are at risk of developing radiotherapy-related insufficiency fractures, which are associated with increased morbidity and pose a significant burden to patients’ quality of life and to the health system. …”
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